• Journal of The Korean Society of Grassland and Forage Science
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• v.33 no.4
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• pp.313-318
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• 2013

A study was conducted to determine if subacute ruminal acidosis (SARA) induced by feeding high level of non-structural carbohydrates results in increases in lipopolysaccharides (LPS) of peripheral blood in dairy cattle. In this experiment four Holstein steers, two of which having ruminal canulae with indwelling probes placed for measuring long term pH changes, were alloted into two dietary treatments in a cross-over design, where an acidogenic diet (AD) was formulated by including high amount of non-structural carbohydrates (NSC) based on corn silage and corn flake as TMR ingredients. Data for ruminal pH change and plasma LPS concentration were compared against normal diet (ND) which contained grass hay as forage and low NSC ingredients. Feeding AD for more than 14 days to animals brought about a pH change as low as less than 5.8 for more than 4 hours, which made good contrast to ND fed animals. Decreased ruminal pH also had an effect on LPS concentrations which showed significantly higher level for AD compared with ND. Therefore, plasma LPS concentration may be used as an effective indicator to verify acidosis whether it is acute or chronic. Na-bentonite and Propylene glycol, which are frequently included in dairy TMR as additives, helped decrease ruminal pH by buffering and then ultimately alleviates SARA. Therefore, it could also be helpful to lower the occurrence of laminitis which is often caused by increased blood endotoxin (LPS) concentration.

• 정보화사회
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• s.134
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• pp.32-34
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• 1999

삼보컴퓨터 이용태 회장은 우리나라에 컴퓨터를 처음 도입한 분으로 잘 알려져 있다. 아마도 그래서 최근의 컴퓨터 산업이 누리고 있는 호황을 바라보는 이 회장의 감회는 그만큼 남다를 것이다. 국내 컴퓨터 산업의 산증인인 이용태 회장을 만나 우리나라 컴퓨터 산업의 역사와 21세기 전망을 들어보았다.

• 베이커리
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• no.1 s.426
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• pp.70-71
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• 2004

한국 제과역사의 산증인 (사)대한제과협회 조승환 고문이 미수가 가까운 나이에 한국 제과업계의 역사에 한 획을 긋는 큰일을 해냈다. 5년이라는 긴 세월 동안 우리나라는 물론 미국과 일본에 있는 자료까지 샅샅이 훑어서 100여 년의 한국 제과 역사가 고스란히 담겨있는 <한국 빵 과자문화사>를 펴내 후손들에게 우리나라 제과업계의 소중한 기록을 남길 수 있도록 한 것이다.

• The Science & Technology
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• v.28 no.2 s.309
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• pp.67-69
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• 1995

"21세기를 움직이는 역사의 원동력은 과학기술환경사관입니다" 우리나라 국토건설사업의 산증인인 전교통부장관 안경모박사는 79세라는 나이도 잊은채 환경운동자금을 마련하겠다고 대덕연구단지안에 '녹원'이라는 음식점을 차려 운영하고 있다.

• KAPE Magazine
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• s.240
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• pp.10-11
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• 2016

전국 최대 단일규모의 직영농장인 <소백양계>. 매일 50만 개 이상의 건강한 계란만을 담아내는 이곳에 60여 년간 한 길을 걸어온 사람이 있다. 바로 대한민국 양계의 산증인이라 말할 수 있는 손병원 대표(83), "계란이 내 인생의 전부"라고 단언할 수 있는 명인을 만나 양계에 대한 조언을 들어본다.

• The monthly packaging world
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• s.315
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• pp.92-95
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• 2019

'여러 방면에 박식한 사람'을 뜻하는 '만물박사(萬物博士)'라는 말이 있다. 포장과 관련된 방면에 박식한 '포장만물박사(包裝萬物博士)'라 말할 수 있는 인물이 있다. 김선창 (주)남경 회장이다. 그는 (사)한국포장협회 7대와 8대 회장을 역임한 한국 포장산업의 산증인이자 국내 최고의 연포장 전문가이다. 김선창 회장을 만나 우리나라 연포장 기술 개발의 역사를 들어보았다.

• Childhood Kidney Diseases
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• v.8 no.1
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• pp.63-67
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• 2004

A 5-year-old girl was admitted because of an acute onset of weakness in her extremities. She had experienced a similar episode before but had recovered spontaneously. She had previously been diagnosed with distal renal tubular acidosis(RTA) at the age of 2 months. During the period of acute paralysis, her serum potassium level was 1.8 mmol/L and the muscle enzymes were markedly raised suggesting massive rhabdomyolysis. Although hypokalemia is common in renal tubular acidosis, acute paralytic presentation is uncommon and is rarely described in children. We report a case of distal RTA complicated with hypokalemic paralysis with a brief review of related literatures.

• Tuberculosis and Respiratory Diseases
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• v.60 no.5
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• pp.548-553
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• 2006

Background : Alcoholic ketoacidosis(AKA) is a metabolic disturbance that is caused by prolonged and excessive alcohol consumption. Though the prognosis is reportedly good, its outcome is unclear in some cases that are combined with multi-organ failure. There are few reports of an analysis of cases admitted to an intensive care unit(ICU) Method: Cases of AKA admitted to the ICU over the last 5 years were retrospectively analyzed. Severe AKA was characterized by multi-organ failure that required treatment in an ICU Results : All patients were males with a history of excessive alcohol consumption. Five of them (50%) mainly complained of gastrointestinal symptoms (nausea, vomiting, diarrhea), showing metabolic acidosis with an increased asmolar and anion gap. Rhabdomyolysis with acute renal failure was the most common combined organ failure. Mechanical ventilation was performed in 80%. Six patients died and 4 patients survived. In the surviving patients, the arterial blood gas analysis(ABGA) was normalized within 12 hours after admission. Conclusion : In severe AKA patients, rhabdomyolysis with acute renal failure was the most common complication. The mortality rate was high and death from shock occurred within 3 days.

• Neonatal Medicine
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• v.17 no.2
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• pp.254-261
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• 2010

Little is known about neonatal mitochondrial disease, though mitochondrial metabolic disorders may often present in the neonatal period because of the high energy requirement of neonate. In newborn period, common presentations are not specific and the disease course may be rapid and fatal. In this study, we report three cases of neonatal mitochondrial disease. The first case was strongly suspected because of sudden seizure and mental change with severe lactic acidosis, and multiorgan failure. Plasma lactate/pyruvate (L/P) ratio was increased to 55.6 with marked lactic aciduria and increased plasma alanin up to 2,237 nmol/mL. In the second patient, a peritoneal dialysis was performed for acute adrenal and renal failure, but metabolic acidosis persisted. Plasma L/P ratio was increased to 23.9, and MRC I (mitochondrial respiratory chain defect) was diagnosed through the enzymatic analysis of the muscles. The third case showed repetitive episode of lactic acidosis during the first two months of life, hypotonia, failure to thrive and feeding difficulties. We found markedly increased cerebrospinal fluid L/P ratio up to 57 though plasma L/P ratio(19.4) was borderline with increased plasma lactate. The lactate peak was prominent in brain magnetic resonance spectroscopy (MRS). MRC II was confirmed through muscle biopsy. Plasma lactate level and lactate peak of brain MRS were normalized after conservative treatment.

• Childhood Kidney Diseases
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• v.10 no.1
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• pp.58-64
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• 2006

In the clinical state of vitamin D deficiency, it is possible that associated phosphate depletion, parathyroid hormone excess, and hypocalcemia may all depress the proximal tubular reabsorption of bicarbonate, in addition to abnormal skeletal modeling or remodeling, Although nutritional rickets is considered a rare disease in developed countries nowadays, cases of vitamin D deficient rickets caused by various unhealthy lifestyles such as insufficient exposure to sunlight, breast feeding infants without giving vitamin D supplements, unbalanced vegetarian diets of breast feeding mothers, low-birth weight, and maternal deficiency of vitamin D or calcium are increasing. Here, we present the case of an 8 month old girl, who was completely breastfed without any weaning diet or infant vitamin supplements. She visited our emergency room with hypocalcemic seizure and subsequently was diagnosed with vitamin D deficient rickets accompanied by overt bone changes and proximal renal lobular acidosis. After intravenous(IV) and oral calcium replacement therapy(IV calcium gluconate injection 1 mEq/kg/day for 6 days, 2 mEq/kg/day for 4 days followed by oral calcium gluconate administration 4 g/day for 3 days) with vitamin D supplement(Alfacalcidol 0.5 mcg/day) during admission, serum calcium level was normalized with clinical improvement. Oral sodium bicarbonate(0.6 g/day) was administered from the $2^{nd}$ hospital day for 2 weeks, which normalized the serum bicarbonate(measured by $tCO_2$) level. Calcium and vitamin D replacement were continued for 2 weeks and 3 months each. After discontinuing medications, follow up laboratory findings showed good maintenance of serum calcium, alkaline phosphate and bicarbonate levels with complete improvement of bone X-ray findings.