• Title/Summary/Keyword: 비정상 전도

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An Improvement on the Analysis Techniques of Environmental Radioactivity Around Nuclear Power Plants (원전주변 환경방사능 분석기술의 개선(I))

  • Kim, Soong-Pyung;Chae, Gyung-Sun;Chung, Woon-Kwan
    • Journal of Radiation Protection and Research
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    • v.20 no.1
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    • pp.8-15
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    • 1995
  • An estimate of a change in radioactivity's circumstances around the nuclear power plant is validated with the results of the radioactivity measurements are compared. In this study, to further enhance the reliability of the results obtained from the environmental radioactivity measurements and analysis around the nuclear power plants that have been carried out up to the present. In the korea standard, there is the technical analysis guide for general stable chemical element's, but there is not the technical analysis guide for the radionuclei. therefore the environmental sample collection, the pretreatment of the sample and radionuclide analysis in the sample, the result's of the environmental radioactivity measurements by each organization, etc. are different. It is not sufficient for the database to forecasting a change in radioactivity's circumstances. A comparative study of collection and pretreatment techniques for the soil sample, the results by comparison, the method of minimizing the relative error are proposed. At one side of sample collection, there are going to considered that the surroundings of sample collection like the lay of the land, the provision of the selection standard for the area and pathway of radionuclide adhesion, the coherence of sample collection, etc.. at another side of pretreatment of the sample and measurement in the case of soil sample, how to do homogeneously the soil particle size and the standard tools, i.e. kinds of meshes, must to be selected.

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Treatment of Infection after Anterior Cruciate Ligament Reconstruction: Graft Retention (전방 십자 인대 재건술 후 감염의 치료: 이식건의 보존)

  • Kim, Hyoung-Jun;Koh, Hae-Seok;Moon, Chan-Woong;Choi, Nam-Yong;In, Yong;Kim, Min-Woo
    • Journal of the Korean Arthroscopy Society
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    • v.11 no.2
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    • pp.99-103
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    • 2007
  • Purpose: To report the results of graft retention treatment for infection cases after anterior cruciate ligament(ACL) reconstruction. Materials and Methods: From a group of 511 consecutive ACL reconstruction patients, we report 5 who sustained septic arthritis. All patients underwent arthroscopic lavage, debridement, synovectomy with graft retention, and treatment with intravenous antibiotics. Results: All patients were evaluated at an average of 34 months after operation. The infection was successfully eradicated. No patient showed instability with KT-2000 arthrometer testing. The clinical outcome was inferior to normal ACL reconstruction patients. Two patients were graded as nearly normal and 3 patients were graded as abnormal with International Knee Documentation Committee evaluation form. Conclusion: There were no recurrences of septic arthritis or bone infection with graft retention treatment for infection patients after ACL reconstruction.

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The Effect of Low-Intensity Treadmill Exercise on Blood Levels of Glucose, Insulin and Lipids in Streptozotocin-Induced Diabetic Rats (저강도 treadmill 운동이 streptozotocin 유도 당뇨쥐의 혈당, 인슐린 및 지질 농도에 미치는 영향)

  • 김세종;서혜림;고정림;염종우;예정복;이선주;김경환;손원협;장은숙
    • Journal of Life Science
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    • v.14 no.2
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    • pp.245-251
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    • 2004
  • Exercise is beneficial to the diabetic patients and streptozotocin-induced diabetic rat has been used for the study of exercise effect. The purpose of this study was to establish the optimal condition of induction of hyperglycemic diabetic rat using streptozotocin and to examine the preventive effect of treadmill exercise on the diabetic rat before and after streptozotocin injection. Intraperitoneal injection of increasing amount of streptozotocin up to 40 mg/kg dose-responsively induce hyperglycemic diabetic rat and inversely reduced the blood insulin level. Body weight was also gradually reduced with the increasing amount of streptozotocin. Control and diabetic rats exercised for 4 weeks before streptozotocin injection. The exercise was performed in the treadmill for 25 minutes a day and 5 times a week with low intensity (0 degree tilt, 15 m/min velocity). Following streptozotocin injection, the blood glucose level was measured every week and the rat was sacrificed after 4 weeks to measure the concentration of insulin and blood lipids. The blood levels of glucose and insulin was significantly reduced with exercise before streptozotocin injection, while those were not changed after streptozotocin injection. The levels of blood lipids such as total cholesterol, HDL-cholesterol, LDL-cholesterol and triglyceride were close to normal control rats. From this study, researchers found the optimal condition of preparation of streptozotocin-induced hyperglycemic diabetic rat, and the mild treadmill exercise has beneficial effect on preventing hyperglycemia and hyperlipidemia. Thus, even low intensive running prevent not only diabetes but also diabetic vascular complications.

Optimization for Inspecdtion Planning of Ship Structures Considering Corrosion Effects (부식효과를 고려한 선체구조 검사계획안의 최적화)

  • Sung-Chan Kim;Jang-Ho Yoon;Yukio Fujimoto
    • Journal of the Society of Naval Architects of Korea
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    • v.36 no.4
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    • pp.137-146
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    • 1999
  • Inspection becomes to be important in the safety of structure and economical viewpoint, because structural damage accompanies lots of economical cost and social problems. Especially ship structure is composed of a lot of members and it is impossible to inspect all members continuously. The purpose of this paper is to get optimal inspection plan containing inspection time and method. Crack is one of major modes on the structural failure and can lead to collapse of structure. In this paper, the deteriorating process, which contains inspection to detect the crack before the propagation to large crack, is idealized as Markov chain model. Genetic algorithm is also used to accomplish the optimization of inspection plan. Especially, the probabilistic characteristics of cracks are changed, because ship is operating in corrosive environments and the scantling of structural members is reduced due to corrosion. Non-stationary Markov chain model is used to represent the process of corrosion in structural members. In this paper, the characteristics of indivisual inspection plan are compared by numerical examples for the change of corrosion rate, the cost due to scheduled system down and target failure probability. From the numerical example, it can be seen that the improvement of fatigue life for the members with short fatigue life is the most effective way in order to reduce total maintenance cost.

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Flood Mapping Using Modified U-NET from TerraSAR-X Images (TerraSAR-X 영상으로부터 Modified U-NET을 이용한 홍수 매핑)

  • Yu, Jin-Woo;Yoon, Young-Woong;Lee, Eu-Ru;Baek, Won-Kyung;Jung, Hyung-Sup
    • Korean Journal of Remote Sensing
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    • v.38 no.6_2
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    • pp.1709-1722
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    • 2022
  • The rise in temperature induced by global warming caused in El Nino and La Nina, and abnormally changed the temperature of seawater. Rainfall concentrates in some locations due to abnormal variations in seawater temperature, causing frequent abnormal floods. It is important to rapidly detect flooded regions to recover and prevent human and property damage caused by floods. This is possible with synthetic aperture radar. This study aims to generate a model that directly derives flood-damaged areas by using modified U-NET and TerraSAR-X images based on Multi Kernel to reduce the effect of speckle noise through various characteristic map extraction and using two images before and after flooding as input data. To that purpose, two synthetic aperture radar (SAR) images were preprocessed to generate the model's input data, which was then applied to the modified U-NET structure to train the flood detection deep learning model. Through this method, the flood area could be detected at a high level with an average F1 score value of 0.966. This result is expected to contribute to the rapid recovery of flood-stricken areas and the derivation of flood-prevention measures.

Estimation of Design Rainfalls Considering BCM2 Simulation Results (BCM2 모의 결과를 반영한 목표연도 확률강우량 산정)

  • Lee, Chang Hwan;Kim, Tae-Woong;Kyoung, Minsoo;Kim, Hung Soo
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.30 no.3B
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    • pp.269-276
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    • 2010
  • Climatic disasters are globally soaring due to recent acceleration of global warming. Especially the occurrence frequency of heavy rainfalls is increasing since the rainfall intensity is increasing due to the change of rainfall pattern, This study proposed the non-stationary frequency analysis for estimating design rainfalls in a design target year, considering the change of rainfall pattern through the climatic change scenario. The annual rainfalls, which are regionally downscaled from the BCM2 (A2 scenario) and NCEP data using a K-NN method, were used to estimate the parameters of a probability distribution in a design target year, based on the relationship between annual mean rainfalls and distribution parameters. A Gumbel distribution with a probability weighted method was used in this study. Seoul rainfall data, which are the longest observations in Korea, were used to verified the proposed method. Then, rainfall data at 7 stations, which have statistical trends in observations in 2006, were used to estimate the design rainfalls in 2020. The results indicated that the regional annual rainfalls, which were estimated through the climate change scenario, significantly affect on the design rainfalls in future.

NORMOBARIC OXYGEN($O_2$) ADMINISTRATION EFFECT ON ATTENTION AND MEMORY FUNCTION IN TEENAGE ADOLESCENTS (10대 청소년의 주의력과 기억능력에 미치는 정상기압 산소흡입 효과)

  • Kim, Byung-Hyo;Kim, Young-Mi;Cho, Soo-Churl;Kim, Boong-Nyun
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.13 no.1
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    • pp.76-84
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    • 2002
  • Objectives:This study was conducted to investigate the effect of oxygen on attention and memory functions in healthy adolescents. Methods:The participant subjects were recruited from local advertisement. All subjects are students attending ordinary middle and high school. Their degree of achievement was average or below average. Before the study, its nature and purpose were fully explained to the patients and their parents, and a written informed consent was obtained from each child's parent and a written assent from each child for entire the procedure. The Ethics Committee and Clinical Research Committee of Gyeongsang National University Hospital approved the protocol. For baseline assessment, all subjects received tests for attention and memory. All tests were conducted by a certified psychologist. Stroop test, continuous performance test and trail making test A and B were used for evaluation of attention. As memory tests, we used memory assessment scale(MAS), standardized memory assessment tools. Ten to fourteen days after initial assessments, same tests was applied to the same subjects after prior 5 minute oxygen inhalation. Results:1) Attention test:Improved performances in trail making part B, and stroop test were found in normobaric oxygen inhalation group compared to air inhalation group. Improved reaction time in those tests seemed to reflect the enhanced executive prefrontal activity. 2) Memory test:More words and digits memorization were found in short-term memory subscale score in MAS in oxygen inhalation group compared to air inhalation group. This finding suggested the improved working memory function after oxygen inhalation. Conclusion:Though interpreted cautiously, these results suggested that normobaric oxygen inhalation could enhance executive function and working memory of prefrontal lobe. Further study, however, should be performed to investigate the mechanism of effects of oxygen on cognitive enhancement.

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Longitudinal flowcytometric measurement of respiratory burst activity of neutrophils in patients with pneumonia (폐렴경과 중 순환 호중구의 Respiratory Burst 활성도 변화)

  • Lee, Jae Myung;Lee, Jong Min;Kim, Dong Gyu;Choi, Jeong Eun;Mo, Eun Kyung;Park, Myung Jae;Lee, Myung Goo;Hyun, In Gyu;Jung, Ki-Suck;Park, Chan Jeoung
    • Tuberculosis and Respiratory Diseases
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    • v.43 no.5
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    • pp.728-735
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    • 1996
  • Background : Recognition and ingestion of opsonized microorganisms by neutrophils induces the burst of oxidative metabolic activity. Products of the respiratory burst activity provide powerful oxygen dependent killing mechanism. Measurement of respiratory burst activity has been a major indicator of the functional capacity of neutrophils. We determined the respiratory burst activity of neutrophils in patients with pneumonia and observed the changes during the clinical course of pneumonia. Methods: The EDTA blood was drawn from 24 normal controls and same numbers of pneumonia patients. The respiratory burst activity(with the production of $H_2O_2$ which changes nonfluorescent DCF-DA to green fluorescent DCF) in the non-stimulated state and the stimulated state with fMLP and PMA of neutrophils was measured by flowcytometry at day 1, 3, 5, 7 and 9 of admission. Results: The respiratory burst activity of neutrophils was mildly increased by stimulation with fMLP. But there was no statistical significance between normal control and patients with pneumonia. The respiratory burst activity of neutrophils was markedly increased by stimulation with PMA in both groups. There was a significant difference in response to PMA between normal control and patients with pneumonia. The production of hydrogen peroxide from neutrophils was decreased during early course of pneumonia and it was recuperated gradually to normal level in 9 days. Conclusion : Hydrogen peroxide production from neutrophils was suppressed during early course of pneumonia and restored after treatment. It is suggested that the production of oxygen radical in response to PMA stimulation from each neutrophils is decreased rather than increased during the early course of pneumonia.

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Effects of Vitamin E on the Metallothionein Synthesis in Streptozotocin-induced Diabetic Rats (Streptozotocin유발 당뇨쥐에 있어서 Metallothionein 합성에 미치는 비타민 E의 영향)

  • 이순재;최원경
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.24 no.2
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    • pp.183-194
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    • 1995
  • The purpose of this study was to investigate the effect of vitamin E on the synthesis of the metallothionein in the liver of streptozotocin (STZ)-induced diabetic rats. Sprague-Dawley male rats($220{\pm}10mg$) were randomly assigned to one control and three STZ-diabetic groups. Diabetic groups were classified to STZ-0E(vitamine E free diet), STZ-40E(40mg vitamin E/kg of diet) and STZ-400E(400mg vitamin E/kg of diet) according to the level of vitamin E supplementation. Blood glucose levels of STZ-diabetic rats were three times higher than that of control. The contents of vitamin E in liver were lower signifciantly STZ-0E, STZ-40E groups by 50%, 36% compared with that of control. Lipid peroxide values(LPO) in liver were higher 5.6 and 2.5 times in STZ-0E and STZ-40E groups than that of control. Plasma cortisol levels were higher STZ-0E and STZ-40E groups compared with those of control, but cortisol levels were lower significantly in STZ-400E group compared with those of the STZ-0E and the STZ-40E groups. The plasma insulin levels were lower in all three STZ-diabetic group compared with that of control, but were not affected by the level of dietary vitamin E. The metallothionein (MT) contents in liver, kidney and small intestine were five times higher in STZ-0E, STZ-40E and STZ-400E compared with that of control, but STZ-400E group was lower in the MT contents in tissues compared with that of STZ-40E group. Zn-MT peak in STZ-diabetic rats liver increased than that of control by Sephadex G-75, and Zn-MT peak divided into MTI and MTII peaks by DEAE Sephadex A-25 column chromatography. The present results indicate that STZ-induced diabetic rats are more sensitive to oxidative stress, leading to the acceleration of lipid peroxidation process, which can be more promoted low level of dietary vitamin E. And the result may that increase synthesis of MT induced in the liver of diabetic rats increased so it can be sure that the diabetes is one of the MT induce factor by free radical generation. And high vitamin E supplementation reduced total MT contents of liver, kidney and small intestine and the peak of purified Zn-MT. Through the results of these experiments, we can conclude that MT might be the free radical scavenger.

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Protective Effects of Korean Panax Ginseng Extracts against TCDD-induced Toxicities in Rat (랫드에서 TCDD 투여에 의해 유도된 생체독성의 고려홍삼 추출물에 의한 억제 효과)

  • Choi, Soo-Jin;Sohn, Hyung-Ok;Shin, Han-Jae;Hyun, Hak-Cheol;Lee, Dong-Wook;Song, Yong-Bum;Lee, Soo-Hyun;Gang, Dong-Ho;Lim, Hak-Seob;Lee, Cheol-Won;Moon, Ja-Young
    • Journal of Ginseng Research
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    • v.32 no.4
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    • pp.382-389
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    • 2008
  • To achieve a better understanding of protective effects of water extracts of Panax ginseng against TCDD-induced toxicities, we monitored physiological and clinical changes in rat for 4 weeks after administrations of each Panax Ginseng extract or TCDD, and co-administration of the two materials. For this study, 120 male Sprague-Dawley (SD) rats weighing 190-210 g each (8 weeks old) were divided into four groups: TCDD-administered, co-administered group with TCDD and ginseng extract, ginseng extract-administered, and control group. The TCDD-administered group received single dose of TCDD in a corn oil vehicle ($25\;{\mu}g/kg$ body weight) by intraperitoneal administration on Day 1. The Panax ginseng extracts-administered group received intraperitoneally 100 mg/kg body weight every other day for one month. For the co-administered group with TCDD and ginseng extracts, Panax ginseng extracts were intraperitoneally administered to rats at 100 mg/kg body weight every other day for one month after a single intraperitoneal dose of $25\;{\mu}g$ of TCDD/kg body weight on Day 1. Panax ginseng extracts attenuated the mortality induced by TCDD administration. The extracts also slightly attenuated the TCDD-induced body weight loss. Administration of TCDD alone increased liver weight at 2, 5, and 16 days after administration of TCDD. Administration of Panax ginseng extracts rather decreased liver weight through whole the experimental period, but which was statistically insignificant. Administration of TCDD alone at $25\;{\mu}g/kg$ body weight increased both serum enzyme activities of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) at 32 days, indicating that liver damage occurred maximally at that time. Ginseng extract administration caused insignificant changes in serum ALT, but gradually decreased in AST as the exposure time increased. Coadministration of TCDD and ginseng extracts caused serum AST activity to significant recovery to normal value at 16 days and 32 days after exposure to TCDD. The extracts also significantly decreased the TCDD-induced ALT activity after 16 days of TCDD administration. These results suggest that Panax ginseng extracts may possess a protective effect against TCDD-induced toxicities including hepatotoxicity in rats.