• Title/Summary/Keyword: 비정상 전도

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The Elimination of ion Implantation Damage at the Source/Drain Junction of Poly-Si TFTs (이온주입에 의한 소오스/드레인 접합부 결함을 제거한 다결정 실리콘 박막 트렌지스터)

  • Kang, Su-Hyuk;Jung, Sang-Hoon;Lee, Min-Cheol;Park, Kee-Chan;Han, Min-Koo
    • Proceedings of the KIEE Conference
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    • 2002.07c
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    • pp.1410-1412
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    • 2002
  • TFT의 게이트 전극을 형성하기 전에 소오스/드레인 이온 주입과 ELA를 수행함으로써 이온 주입에 의해 발생하는 결정 결함을 줄이는 새로운 poly-Si TFT를 제안한다. 한번의 ELA 공정을 통해서 채널 실리콘 박막의 결정화와 소오스/드레인의 불순물 활성화를 동시에 이루어 접합부의 결함을 치유하였고, 이온 주입에 의해서 비정질화된 소오스/드레인 실리콘과 채널 비정질 실리콘의 용융조건 차이를 이용하여 소오스/드레인 접합부에 실리콘 그레인의 수평성장을 유도하였다. 제안된 소자는 기존의 소자(이동도 : 86 $cm^2/V{\cdot}S$, ON/OFF 전류비 $6.1{\times}10^6$)에 비해 우수한 특성(이동도 : 171 $cm^2/V{\cdot}S$, ON/OFF 전류비 $4.1{\times}10^7$)을 나타내었다. LDD나 off-set 구조 없이도 소오스/드레인 접합부의 결함이 완전히 제거되어 누설전류가 감소하였고 소오스/드레인 접합부 결함이 있던 자리에 1 ${\mu}m$ 이상의 수평성장 그레인이 위치함으로써 ON 전류도 증가하여 ON/OFF 전류비가 크게 개선되었다.

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Outlier Diagnostics and Resolution to determine Obesity Status in the Korean National Health Insurance Research Database (국민건강보험공단 자료에서 비만실태 파악을 위한 이상치 진단 및 해결)

  • Kim, Dong Wook;Yoon, Ho Soon
    • The Journal of the Korea Contents Association
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    • v.17 no.9
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    • pp.476-485
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    • 2017
  • This study was analyzed obesity status by divided into six classification based on the body mass index(BMI) established by World Health Organization-Western Pacific Regional Office(WHO-WPRO) through National Health Insurance Service(NHIS). In the middle of process, problems of outlier solved by presenting the median repeated interpolation. Unlike linear and Lagrange interpolation, median repeated interpolation may be useful in multiple outlier contained dataset. As a result, we found that extreme low and obesity weight gradually increased and the frequency of normal body weight gradually decreased. Especially, the increase of obesity in men and women of lower age group is increasing. Overall, this study suggests that national measures need to be taken before health problems arising from obesity can spread to other social problems.

Myocardial Perfusion SPECT as a Screening Test before Planned Vascular Surgery for Predicting Perioperative Cardiac Complications (혈관 수술 후 심장 합병증 발생을 예측하기 위한 선별 검사로서 심근 관류 단일 광자 단층촬영의 유용성에 대한 연구)

  • Lee, Hyung-Chae;Hwang, Youn-Ho;Wi, Jin-Hong;Jun, Hee Jae;Lee, Yang-Haeng;Cho, Kwang-Hyun
    • Journal of Chest Surgery
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    • v.43 no.1
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    • pp.25-32
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    • 2010
  • Background: Patients with vascular diseases commonly have coronary artery disease and associated cardiac problems. Therefore, their underlying heart diseases may be induced or exacerbated after vascular surgery. The effectiveness of SPECT imaging, which is a relatively simple and non-invasive imaging modality, for assessing these underlying heart diseases is still controversial. This study was performed to evaluate the clinical effect of tests and treatment based on SPECT imaging prior to vascular surgery on the development of post-operation cardiac complications. Material and Method: Sixty three patients who were treated at Inje University Pusan Paik Hospital between April 2004 and September 2007 and who underwent adenosine infusion technetium-99m (Tc-99m) tetrofosmin SPECT imaging prior to vascular surgery were selected for this study and we retrospectively reviewed their records. Result: The sensitivity and specificity of detecting a perfusion defect on SPECT to predict the development of cardiac complications was relatively low at 41.2% and 52.2%, respectively. However when coronary angiographies were done on the patients with abnormal SPECT and this was followed by aggressive treatment such as coronary artery intervention and coronary artery bypass grafting based on the angiography results, there was a tendency for lower cardiac complication rates. Conclusion: SPECT imaging shows low effectiveness as a screening test for predicting cardiac complications after vascular surgery.

Effect of NMDA Receptor Antagonist on Local Cerebral Glucose Metabolic Rate in Focal Cerebral Ischemia (국소뇌허혈에서 NMDA 수용체 길항제가 국소 뇌포도당 대사율에 미치는 영향)

  • Kim, Sang-Eun;Hong, Seung-Bong;Yoon, Byung-Woo;Bae, Sang-Kyun;Choi, Chang-Woon;Lee, Dong-Soo;Chung, June-Key;Roh, Jae-Kyu;Lee, Myung-Chul;Koh, Chang-Soon
    • The Korean Journal of Nuclear Medicine
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    • v.29 no.3
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    • pp.294-306
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    • 1995
  • There has recently been increasing interest in the use of NMDA receptor antagonists as potential neuroprotective agents for the treatment of ischemic stroke. To evaluate the neuroprotective effect of the selective non-competitive NMDA receptor antagonist MK-801 in focal cerebral ischemia, local cerebral glucose utilization (ICGU) was examined in 15 neuroanatomically discrete regions of the conscious rat brain using the 2-deoxy-D[$^{14}C$] glucose quantitative autoradiographic technique 24 hr after left middle cerebral artery occlusion (MCAO). Animals received MK-801 (5 mg/kg i.v.) or saline vehicle before (20-30 min) or after (30 min) MCAO. Both pretreatment and posttreatment of MK-801 increased occluded/non-occluded ICGU ratio in 7 and 5 of the 15 regions measured, respectively (most notably in cortical structures). Following MK-801 pretreatment, there was evidence of widespread increases in ICGU not only in the non-occluded hemisphere (12 of the 15 areas studied) but also in the occluded hemisphere (13 of the 15 areas studied), while MK-801 postreatment did not significantly increase ICGU both in the normal and occluded hemispheres. These data indicate that MK-801 has a neuroprotective effect in focal cerebral ischemia and demonstrate that MK-801 provides widespread alterations of glucose utilization in conscious animals.

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Dietary behaviors and nutritional status according to the bone mineral density status among adult female North Korean refugees in South Korea (한국에 거주하고 있는 북한이탈주민 여성의 골밀도에 따른 식생활과 영양상태)

  • Kim, Su-Hyeon;Lee, Soo-Kyung;Kim, Sin-Gon
    • Journal of Nutrition and Health
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    • v.52 no.5
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    • pp.449-464
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    • 2019
  • Purpose: North Koreans could be at higher risk for their bone health because of previous periods of severe famine and the continuing low availability of food. This study determined the bone mineral density (BMD) status and its relationship with dietary behaviors and nutrient intake of North Korean refugees (NKR) in South Korea (SK). Methods: This cross-sectional study analyzed 110 female NKR from a NORNS cohort of a non-probability sample of adult NKR in Seoul. BMD examined by DEXA was used to divide participants into the normal group (NG) and the non-normal group (NNG) according to the WHO guideline. A self-administered questionnaire included questions on age, the socioeconomic situation in North Korea (NK) and SK, the food security in NK and SK, and the health behaviors, dietary behaviors, and food frequency questionnaire administered in SK. A one-day 24-hr recall was conducted and the results were analyzed by using CanPro. SPSS was used to analyze whether BMD and related dietary behaviors and nutrient intakes differed according to the groups. Results: NG (62.7%) was significantly younger and had a lower abdominal obesity score than NNG (p < 0.001). While 14.5% of NG reported experiencing menopause, all of NNG reported experiencing menopause. The NG more frequently consumed the dairy group of foods (9.6 times a week) than did the NNG (4.8 times a week) after the statistics were adjusted for age (p < 0.007). The NG consumed significantly more animal protein and animal calcium than did the NNG (p = 0.01, p = 0.009, respectively). Calcium intake was low with 49.3% of NG, and 78.0% of the NNG reported consuming calcium lower than the estimated average requirement. Only calcium showed an index of nutrient quality lower than one in both groups. Conclusion: These results showed that NKR women and possibly all North Korean women are at high risk for bone health and they consumed low levels of bone-related nutrients, and this should be considered for the nutrition policy for NKR and North Korea.

Medical Expenses during the last 6 Months of Life in Cancer Patients (암 환자의 사망 전 6개월의 의료비용)

  • Park, No-Rai;Yun, Young-Ho;Shin, Soon-Ae;Jeong, Eun-Kyeong
    • Journal of Hospice and Palliative Care
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    • v.2 no.2
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    • pp.109-113
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    • 1999
  • Purpose : Because we don't have inappropriate health care system for the terminal cancer patients, there were abnormal behavior patterns of health care utilization. So, There were needs to develop the comprehensive care for terminal cancer patients. Increased attention is being paid to the futility of life-sustaining treatment and high cost of management of terminal cancer patients Materials and Methods : This study was performed on cancer patients, registered in 1996 Central Cancer Registry, who were as insured person of Korea Medical Insurance and died from January 1997 to June 1998. We studied the day of medical care and medical expenses of 151 cancer patients evaluable. Results : The mean day of inpatient care was 39 days, and the mean days of outpatient care was 14 days in study subjects. Mean expenses per day of medical care, day of inpatient, and day of outpatients care were 85,392 won, 105,908 won, and 40,173 won. 95% of medical expenses is paid to the general hospital, and 85% of medical expenses was paid for inpatient care. About half of all medical expenses in th last 6 months were incurred in the last 60 days of life, and about 30 percent were incurred in the last 30 days. Expenses of outpatients care increased between 6 month and 3 months, after which they decreased. Expenses of inpatients care increased during all last 6months Conclusion : The distribution or medical expenses during the last 6 months in our study is similar to the distribution of American Medicare costs. We need to study medical expenses during the last year of life with large scale and details in order to develop the plan about the management of terminal cancer patient.

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RF 플라즈마 아킹의 PM-tube를 이용한 광량 측정

  • Kim, Yong-Hun;Jang, Hong-Yeong
    • Proceedings of the Korean Vacuum Society Conference
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    • 2010.08a
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    • pp.125-126
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    • 2010
  • 플라즈마 아킹은 PECVD, 플라즈마 식각 그리고 토카막과 같은 플라즈마를 이용하는 여러 공정과 연구 분야에서 문제점을 야기시켜왔다. 하지만, 이에 대한 연구는 아킹 현상의 불규칙성과 과도적인 행동으로 인해 미비한 상태이다. 특히, RF 방전에서의 아킹 연구는 DC 방전에서의 아킹 연구에 비해 많이 부족한 것이 현실이다. 플라즈마 아킹은 집단전자방출(collective electron emission)에 의한 스파크 방전(spark discharge)현상이다. 집단전자방출은 전계방출(field emission)이나 플라즈마와 쉬스를 두고 인접한 표면위에서의 유전분극(dielec emission)에 의해 발생한다. 이렇게 방출된 집단 전자들은 쉬스에서 가속되어 에너지를 얻게 되고 원자와의 충돌로 전자 아발란체를 일으킨다. 이렇게 배가된 전자들은 아킹 스트리머(arcing streamer)를 형성하게 되고 아킹 발생 시 높은 전류와 공정 실패의 원인이 된다. 우리는 $30cm{\times}20cm$ 크기의 사각 전극을 위 아래로 가진 챔버에서 Ar 가스를 RF(13.56 MHz)파워를 이용해 방전시켰다. 방전 전압과 전류는 파워 전극 압단에서 High voltage probe (Tektronix P6015A)와 Current probe (TCPA300 + TCP312)를 이용해 측정했다. 플라즈마 아킹시 변하는 플라즈마 플로팅 포텐셜은 챔버 중앙에 위치한 랑뮈프 프로브에 의해 측정되고 챔버 옆의 뷰포트 앞에 위치한 PM-tube를 이용해 아킹시 변하는 광량을 측정한다. RF 방전에서의 플라즈마 아킹은 아킹시 플로팅 포텐셜의 변화에 의해 크게 세부분으로 나눌 수 있다. 아킹 발생과 동시에 급격히 감소하는 감소부분 (약 2us) 그리고 감소한 포텐셜이 유지되는 유지부분 (약 0~10ms) 그리고 감소했던 포텐셜이 서서히 원래 상태로 회복되는 회복부분(약 100 us)이다. 아킹 초기시 방출된 집단 전자들과 원자들간의 충돌에 의해 형성된 아킹 스트리머는 플라즈마 전체를 단락시키게 되고 이로 인해 플로팅 포텐셜은 급격히 감소하게 된다. 이렇게 감소한 플로팅 포텐셜은 아킹 스트리머가 유지되는 한 계속 감소한 상태를 유지하게 된다. 그리고 플라즈마를 섭동했던 아킹 스트리머가 중단되면 플라즈마는 섭동전의 원래 상태로 돌아가려 하기 때문에 플로팅 포텐셜은 서서히 증가하면서 원래 상태로 회복된다. 플라즈마 아킹 발생시 생성되는 아킹 스트리머는 순간적으로 많은 전자들을 국소적으로 생성하게 되고 이 전자들에 의해 광량이 순간적으로 증가하게 된다. PM-tube (750.4 nm)에 의해 측정된 아킹시 광량은 정상방전 상태의 두배 가량이 된다. 그리고 이 순간적으로 증가된 광량은 시간이 지남에 따라 감소하게 되고 정상방전 일때의 광량이 된다. 광량이 증가한 후 정상방전 상태의 광량에 이르는 부분은 플로팅 포텐셜이 감소한 상태에서 유지되는 부분과 일치하고 이는 플로팅 포텐셜의 유지부분동안 아킹 스트리머가 발생하고 있다는 간접적인 증거가 된다. 그리고 정상 방전 상태 일때의 광량이 되면 아킹 스트리머가 중단되었다는 것이므로 그 시점부터 플로팅 포텐셜은 정산 방전상태 일 때의 포텐셜로 복구되기 시작한다. 이처럼 PM-tube를 이용한 아킹 광량 측정은 아킹 스트리머를 간접적으로 측정하게 하고 아킹 스트리머를 이용해 아킹시의 플로팅 포텐셜의 변화를 설명하게 해 준다. 응용적인 측면에서 아킹 광량 측정을 이용한 아킹 판독은 방전 전류와 방전 전압과 같은 전기적 신호를 이용한 아킹 판독에 비해 여러가지 장점을 가진다. 우선, 전기적 신호를 이용한 아킹 판독처럼 매칭 회로나 플라즈마를 섭동시키지 않는다. 그리고 원하는 부분의 아킹만을 판독하는 것도 가능하며 photo-diode를 이용할 경우 전기적 신호를 이용하는 것에 비해 경제적으로 유리하다.

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Analysis of masseter muscle in facial asymmetry before and after orthognathic surgery using 3-dimensional computed tomography (3차원 전산화 단층 사진을 이용한 안면비대칭 환자의 악교정 수술 전, 후 교근 분석)

  • Seo, Seung-Ah;Baik, Hyoung-Seon;Hwang, Chung-Ju;Yu, Hyung-Seog
    • The korean journal of orthodontics
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    • v.39 no.1
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    • pp.18-27
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    • 2009
  • Objective: The purpose of this study was to understand the differences in masseter muscle(MM) between the shifted and non-shifted sides in facial asymmetry patients, and the changes shown by MM after mandibular surgery. Methods: Pre- and post-operative CT scans were performed on 12 Class III patients with facial asymmetry who were treated by intraoral vertical ramus osteotomy and 10 subjects with normal occlusion. Using the V-works 4.0 program(Cybermed, Seoul, Korea), 3-dimensional images of the mandible, and MM were reconstructed, and evaluated. Results: In the asymmetry group, the MM angle between the shifted and non-shifted sides was only significantly different(p<0.05). Compared with normal occlusion, the asymmetry group showed a significantly smaller volume and maximum cross-sectional area in both sides of MM(p<0.05). After mandibular surgery, the angle of MM(p<0.01) and differences in angle between the shifted and non-shifted sides of MM(p<0.05) were significantly decreased. The thickness in the maximum cross-sectional area was significantly increased(p<0.01). After surgery, MM in facial asymmetry patients was similarly changed to those in the normal occlusion group except for widths. Conclusions: MM in facial asymmetry was definitely different from those in normal occlusion. However, this study suggests that MM changed symmetrically in conjunction with the mandible after proper mandibular surgery.

Neurobiochemical Analysis of Abnormal Fish Behavior Caused by Fluoranthene Toxicity (Fluoranthene 독성에 기인하는 비정상적 어류행동의 신경생화학적 분석)

  • 신성우;조현덕;전태수;김정상;이성규;고성철
    • Environmental Analysis Health and Toxicology
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    • v.18 no.2
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    • pp.155-163
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    • 2003
  • Fluoranthene, a common polycyclicaromatic hydrocarbon (PAH), exhibits phototoxicity which may affect aquatic organisms. The eventual goal of this study is to develop a biomarker of Japanese medaka (Oryzias latipes) used in monitoring hazardous chemicals in the ecosystem. In this study we investigated neural toxicity of fluoranthene in Japanese medaka (Oryzias latipes) along with comparative analysis of corresponding behavioral response. The untreated individuals shooed normal behavioral characteristics (i. e., smooth and linear movements). The treated fish, however, showed stopping and abrupt change of orientation (100 ppb), and severely reduced locomotive activity and enhanced surfacing activity (1,000 ppb). Treatment of the medaka fish with fluoranthene caused a significant suppresson of acetycholine esterase (AChE) activities in the body portion but not in the head portion. When fish were exposed to 1,000 ppb of fluoranthene for 24 hr, the body AChE activities decreased from 126.${\pm}$31.89 (nmoles substrate hydrolyzed per min per mg protein) to 49.51${\pm}$11.99. Expressions of tyrosine hydroxylase (TH) protein in the different organs from both head and body portions were comparatively analyzed using an immunohistochemical technique. Five organs of the medaka fish showing a strong TH protein expression were the olfactory bulb, hypothalamus, optic lobe, pons and myelencephalon regions. This study provides molecular and neurobehavioral bases of a biomonitoring system for toxic chemicals using fish as a model organism.

Global Distribution of Ocean Color Speckles

  • Chae, Hwa-Jeong;Park, Gyeong-Ae
    • 한국지구과학회:학술대회논문집
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    • 2010.04a
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    • pp.135-135
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    • 2010
  • 1997년에 발사된 해색센서 Sea-viewing Wide Field-of-view Sensor (SeaWiFS)의 클로로필-a 자료는 많은 연구자들에게 전 지구 규모나 지역 규모에 대한 해양표층의 식물 플랑크톤 증식을 연구하는데 널리 활용되고 있다. 그런데 NASA로부터 제공되는 동해의 SeaWiFS Level-3 클로로필 자료에는 비정상적으로 높은 농도 값이 스펙클 형태로 분포한다. 본 연구에서는 1998년부터 2007까지 전구의 SeaWiFS 자료를 이용하여 SeaWiFS 클로로필-a 농도가 가지는 스펙클 오차의 분포 특성에 관해 조사하였다. 10년간의 월별 자료로부터 각 화소의 최댓값을 분석한 결과 정상적 농도 범위에서 벗어난 높은 농도 값이 스펙클 형태로 출현하였다. 이런 특성은 북반구에서 전구의 80% 이상 높게 나타났으며, 특히 $40-75^{\circ}N$의 중위도 영역에 집중분포하였다. 또한 스펙클들은 연안 가까이에서 매우 높게 나타난 반면 연안과 멀리 떨어진 외해에서도 $10-80mg/m^3$정도의 높은 값을 가지고 산발적으로 분포하였다. 스펙클들은 해마다 상당한 연 변동을 보였으며, 해역별로 크게 분포하는 시기가 다르게 나타났다. 북태평양에서는 봄철에 크게 나타난 반면 북대서양에서는 봄철과 가을철에 고르게 분포하였다. 2009년의 SeaWiFS 재처리 이후에 스펙클 오차 보정에 대한 처리가 이루어졌으며, 상당량 줄어든 분포를 보였으나 여전히 자료 안에서 매우 높은 농도로 분포하며 자료에 오차를 유발하고 있다. 따라서 본 연구는 전구에서 나타나는 스펙클 오차 분포 특성을 분석함으로 해색자료가 가지는 오차에 관한 문제점을 제기하였으며, 이를 통해 좀 더 신뢰도 있는 자료를 해양 연구에 사용해야함을 제시한다.

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