• Journal of Korean Medicine for Obesity Research
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• v.4 no.1
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• pp.33-43
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• 2004

Background: Recently obesity has become a social problem in all over the world including Korea. It is known that obesity is closely related with cardiovascular disease. Many studies are carrying out in the relation between several obesity indices, such as body mass index(BMI), waist-circumference(WC), body fat percent and risk factors of cardiovascular disease. Objective: This study was done in order to investigate correlation of obesity and cardiovascular risk factors. Method: We gathered totally 138 subjects who have taken health screening test in university hospital. With the exception of 40 abnormal cases on current illness and laboratory study, 98 healthy cases were analysed. We divided the groups as normal, overweight, obese group according to body mass index $(22.9kg/m^2\;and\;below\;/\;23{\sim}24.9kg/m^2\;/\;25kg/m^2\;and\;above)$and investigated the relationship between obesity based on body mass index(BMI) and cardiovascular risk factors. And investigated the relationship between each cardiovascular risk factor and body mass index, waist-hip ratio, body fat percent. Results: With the exception of blood pressure, other lab data such as total cholesterol, triglycerid, glucose were significantly different between the three groups divided by body mass index$(22.9kg/m^2\;and\;below\;/\;23{\sim}24.9kg/m^2\;/\;25kg/m^2\;and\;above)$. And Correlation coefficient of cardiovascular risk factors with body mass index, waist-hip ratio, body fat precent were acquired. Conclusion: We have concluded that the body mass index and waist-hip ratio body fat precent were predictive factors cardiovascular disease.

• Research in Community and Public Health Nursing
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• v.18 no.3
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• pp.382-390
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• 2007

Purpose: The purpose of this study was to identify the effects of taekwon aerobic on obesity indices and cardiovascular risk factors in middle-aged obese women. Method: Data were collected from 19 middle-aged obese women who participated in taekwon aerobic exercise. This research adopted one-group pretest-posttest design. Taekwon aerobic was applied 3 times in a week for 12 weeks, and the obesity indices and cardiovascular risk factors were checked before and after the program. Body weight, BMI and % body fat for obesity indices were checked, and total cholesterol, triglyceride, HDL-cholesterol and the ratio of total cholesterol/HDL-cholesterol for cardiovascular risk factors were measured. The data was analyzed by paired t-test using SPSS/win 10.0. Results: There were significant differences in body weight, BMI and % body fat after the taekwon aerobic exercise. There was a significant difference in total cholesterol. However, there were no significant differences in triglyceride, HDL-cholesterol and the ratio of total cholesterol/HDL-cholesterol after the taekwon aerobic exercise. Conclusion: This study showed that taekwon aerobic exercise decreased obesity indices and lowered total cholesterol in the cardiovascular risk factors. The results of this study show that taekwon aerobic exercise is effective in enhancing the health of middle-aged obese women.

• Journal of Korean Medicine for Obesity Research
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• v.13 no.1
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• pp.10-16
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• 2013

Objectives: This work aimed to investigate differentiations of Korean medicine's pathological symptoms and SF-12 sub scales among normal, overweight and obese subjects from multi-center case report. Methods: From 2009 to 2011 survey were carried out to 1,589 subjects who took treatment or were hospitalized in 7 Korean medicine hospitals and 3 Korean medicine clinic. Survey include Korean medicine's pathological symptoms and SF-12. Whole survey were obtained from subjects with interviewers. Obesity degree was divided into three groups by body mass index: Normal group is from 18.5 below 23, overweight from 23 below 25 and obese group is over 25. Chi-square test was performed to reveal differentiation response rate of pathologic symptoms among obesity groups. ANOVA test was carried out for compare each group's SF-12 sub scales. Results: Patients of overweight or obesity have more symptoms such as skin itching, swelling, weakness in lower legs, and feverish with swollen joints. Contrary, normal weight group responded symptoms of dry skin more than those of obese group. As a fatigue, obese group have more fatigue feeling at afternoon and evening, compared to high frequency response of normal weight groups' morning fatigue. Obese groups shows low physical scores of health related quality of life, in contrast, high mental scores of that. Conclusions: This is first work of pathologic symptoms shown by obese groups. This would contribute to standardization of Korean medicine's pattern identification as suggestion of classification point for obese groups.

• Korean Journal of Food Science and Technology
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• v.45 no.2
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• pp.199-205
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• 2013

We investigated the anti-obesity effects of Ishige okamurae extract (IOE) on body weight, epididymal adipose tissue weight, plasma lipid levels, and leptin levels in high-fat diet (HFD)-induced obese mice. After inducing obesity by feeding 45% HFD for 4 weeks, C57BL/6J mice were randomly assigned to HFD or HFD containing 5% IOE, and then fed for 6 weeks. The body weight and epididymal adipose tissue weight were increased by HFD, but they were significantly less in animals fed HFD containing 5% IOE than in those fed HFD. Levels of plasma triglyceride, total cholesterol, and LDL-cholesterol were significantly lower, but the HDL-cholesterol level was significantly higher in animals fed HFD containing 5% IOE compared with the HFD group. The plasma leptin level was significantly lower in animals fed HFD containing 5% IOE. The diet containing 5% IOE did not show any adverse effects on liver and kidney functions. These results suggest that IOE has a potential as anti-obesity agent by reducing body weight and lowering the levels of obesity-related factors in plasma.

• Applied Microscopy
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• v.36 no.4
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• pp.271-277
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• 2006

Mast cells (MCs) are granulated cells that play a pivotal role in allergic reaction and inflammation. The granules of mast cells are known to be rich in zinc (Zn). Male Sprague-Dawley rats were used. We injected $200{\mu}L$ of complete Freund's adjuvant (CFA) subcutaneously in the dorsal aspect of one hindpaw Finally, zinc selenium autometallography(AMG) was done by Danscher's method. The present study showed the ultrastructures of zinc-containing mast cells found in inflammatory area following an complete freund's adjuvant (CFA) inoculation into the rat hindpaw. At light microscopic level, mast cells were round or oval, at average $12{\mu}m$ in diameter, with many filopodia extending from the cell surface. Because the rather small and spherical nucleus was centrally placed; it was frequently obscured by the cytoplasmic granules, it sometimes could not be seen. Mast cells were distributed chiefly in the vicinity of small blood vessels. In most preparation many mast cells were ruptured and their granules escaped into the surrounding tissue. In electron micrographs, The secretory granules were at average $0.5{\mu}m$ in diameter and were limited by a membrane. The cell surface contained numerous microvilli and folds. Their interior was heterogenous in appearance. The nucleus was surrounded by large numbers of prominent vesicels and a well developed Golgi apparatus, but scant endoplasmic reticulum.

• Journal of Animal Science and Technology
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• v.53 no.2
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• pp.99-106
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• 2011

This study estimated the genetic parameters of growth-related traits from 11-month-old olive flounder (Paralichthys olivaceus) base population in which wild and cultured broodstocks were introduced. The heritability of body weight, total length, body height, body shape, and condition factor of the base population was estimated to be 0.754, 0.753, 0.789, 0.438, and 0.369, respectively. Genetic correlations between body weight and total length, between body weight and body height, and between total length and body height were 0.969, 0.960, and 0.960, respectively, showing highly positive correlation. Genetic correlations between body weight and body shape, between total length and body shape, between body height and body shape were -0.403, -0.344, and -0593, respectively, showing low negative correlation. Overall, olive flounder might be an appropriate selective breeding species with the high heritability of the traits in an 11-month-old population.

• The Journal of the Korea Contents Association
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• v.9 no.6
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• pp.237-246
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• 2009

This study was carried out to investigate of the associations of Alcoholic & Nonalcoholic fatty liver disease(AFLD & NAFLD) with metabolic syndrome(MS) defined by IDF criteria. We conducted a cross-sectional study of 799 adult males with alcohol consumption underwent laboratory investigation(control 297, alcoholic 206, nonalcoholic 296). The ultrasound scan of the liver was performed to determine the presence and the severity of FLD. We analyzed the association between the severity of AFLD & NAFLD and MS by logistic regression analysis. The distribution of metabolic syndrome was 7.4%, 48.8%, 34.9% in control, AFLD & NAFLD. The association of blood pressure, glucose, triglycerides, obesity were risk factor in AFLD & NAFLD. According to the severity of FLD, AFLD was significantly increased with MS, Obesity, low HDL-cholesterol. MS, High triglycerides was increased significantly in NAFLD(p<0.05). The prevalence of AFLD & NAFLD was increased with increasing the number of features of metabolic syndrome. This study shows that AFLD & NAFLD was closely associated with MS and its components. The patients of AFLD & NAFLD should managed and monitored to prevent metabolic abnormalities.

• 한국체육학회지인문사회과학편
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• v.57 no.4
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• pp.375-386
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• 2018

Due to the rapid increase of the elderly population in Korea, there is a growing interest in 'Healthy Aging.' In this trend, it is important to identify the relationship between their lifestyle factors and quality of life. The purpose of this study was to identify the association of physical activity level, sedentary behavior and health-related quality of life (HRQoL) among Korean older adults. A total of 4,589 older adults at the Sixth and Seventh National Health and Nutrition Examination Survey was analyzed. The results showed that better HRQoL was observed among physically active older female, which was more evident among physically active female with central obesity while no such relationship was observed among older male. On the other hand, higher sedentary time was associated with lower HRQoL in both male and female subjects. Our analyses indicated that central obesity was closely related with HRQoL regardless of their physical activity levels in female subjects. Further analyses investigating association between sub-dimension of HRQoL and sub-domain of physical activity showed that higher transport physical activity was associated with better anxiety/depression score and higher sedentary time was associated with poorer score on mobility, usual activities among male and mobility, self-care, usual activity and anxiety/depression among female. Our finding suggests that physical activity level, sedentary behavior and central obesity associated with HRQoL.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.9
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• pp.3962-3972
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• 2012

The purpose of this study was to analyze the effects of combined exercise on body composition and cardiovascular disease risk factors in sarcopenic obesity elderly women. The subjects for the study were 21 obesity elderly women over 65 years old. They were divided into two groups, the sarcopenic obesity group(n=9) and non-sarcopenic obesity group(n=12). The variables of body composition and CVD risk factors were measured in all the subjects before and after 16-week combined exercise. The findings of this study were as follows; In the sarcopenic obesity elderly women significantly decreased total cholesterol(TC), triglyceride(TG), and left baPWV. The non-sarcopenic obesity elderly women significantly decreased total cholesterol(TC), triglyceride(TG), low density lipoprotein-cholesterol (LDL-C), and left baPWV, but significantly increased high density lipoprotein-cholesterol(HDL-C). The most important finding in this study was that sarcopenic obesity elderly women showed delayed effects of a 16-week combined exercise on HDL, LDL-C, BP, and right baPWV compared to the non-sarcopenic obesity elderly women.

• Korean Journal of Clinical Laboratory Science
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• v.47 no.3
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• pp.97-104
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• 2015

Sleep is not only an essential physiological function, but also serves important roles in promoting growth, maturation, and overall health of humans. There is increasing interest regarding the impact of sleep and its disorders on the regulation of inflammatory processes and end-organ morbidities, particularly in the context of metabolic and cardiovascular diseases (CVD) and their complications. Obstructive sleep apnea syndrome (OSAS) is an increasingly common health problem in children. In the last decade, the emergence of increasing obesity rates has further led to remarkable increases in the prevalence of OSAS, along with more prominent neurocognitive, behavioral, cardiovascular and metabolic morbidities. Although the underlying mechanisms leading to OSAS-induced morbidities are likely multifactorial and remain to be fully elucidated, activation of inflammatory pathways by OSAS has emerged as an important pathophysiological component of the end-organ injury associated with this disorder. To this effect, it would appear that OSAS could be viewed as a chronic, low-grade inflammatory disorder. Furthermore, the concurrent presence of obesity and OSAS poses a theoretically increased risk of OSAS-related complications. In this study, we will critically review the current state of research regarding the impact of insufficient and disrupted sleep and OSAS on the immune processes and inflammatory pathways that underlie childhood OSAS as a distinctive systemic inflammatory condition in children, and will explore potential interactions between OSAS and obesity.