• Investigative Magnetic Resonance Imaging
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• v.13 no.1
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• pp.97-100
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• 2009

Embryonal rhabdomyosarcoma of the head and neck is very rare in adults. We report a case of embryonal rhabdomyosarcoma in the nasal cavity, occuring in a 24-year-old male patient presenting with left nasal obstruction, ipsilateral eye and cheek pain and multiple neck nodules. Rhabdomyosarcoma should be considered in the differential diagnosis of poorly defined soft tissue mass of the nasal cavity not only in children, but also in adults.

• Proceedings of the Acoustical Society of Korea Conference
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• autumn
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• pp.49-52
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• 2000

본 논문에서는 일반적인 강세 판정 법이 갖는 단점을 보완하기 위하여 모델을 기반으로 하는 강세 판정 방법을 제안한다. 기존의 강세 판정 법은 기준 값과의 절대적인 비교에 의해 강세를 판정하게 되므로 발음 환경에 따라 불안정한 성능을 나타낸다. 제안하는 방법은 강세/비강세 모델을 적용한 후보들에 대해 상대적인 비교 값으로 강세를 판정한다. 소량의 강세 음성 데이터베이스로부터 강세/비강세 모델을 훈련하기 위해 적응 훈련 기법을 사용하였다. 실험 결과 $76.53\%의 판정 성공률을 나타내었으며, 이는 제안한 방법이 강세 자동 판정 방법으로 이용 가능성을 보이는 결과이다.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1991.06a
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• pp.41-41
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• 1991

비강 및 부비동 종양 적출시 종양의 침범이나 시야의 확보를 위해 누액 배출계의 절제가 불가피하여 이로 인한 술후 유루가 발생하는 례를 종종 경험하게 된다. 이에 저자들은 누액 배출계의 절제후 적절한 처치 방법에 대해 알아 보고자, 1989년 1월부터 1990년 12월까지 2년간 비강 및 부비동의 양성 또는 악성 종양의 적출시 누액 배출계를 절제한 13례에서 누액 배출계의 처치 방법과 이에 따른 유루의 발생 여부를 후향적으로 검토하여 다음과 같은 결과를 얻었다. 누낭에서 절단한 7례중 6례에서, 누낭에서 절단 후 silastic tube를 4주간 유치한 6례 중 1례에서 유루를 경험하여 누액배출계의 절제시 silastic tube의 유치는 술후 유루 발생의 방지에 도움이 될 것으로 사료된다.

• Proceedings of the Korean Information Science Society Conference
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• 2012.06c
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• pp.320-322
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• 2012

코 내부의 복잡한 기하학적 형상으로 인해 nasal airway의 분리는 많은 어려움을 겪고 있다. 본 논문은 velocimetry of nasal airflow 와 코 수술 계획을 위하여 3차원 공간에서 nasal airway를 interactive semiautomatic으로 분리하고 시각화하는 방법을 제안한다. 제안하는 방법은 ROI(Region-Of-Interest)와 multi-seed 3d region growing(MS3RG)기법을 적용하여 비강을 분리하며 볼륨렌더링 기법을 이용하여 분리된 영역을 3차원 공간에서 직관적으로 확인 할 수 있다. 또한 분리된 3차원 비강 모델은 유동흐름 실험을 위하여 3차원 프린터를 통해 실제 모형으로 제작 가능하다. 그리하여 CT dataset(512*512*175)을 가지고 매뉴얼 세그멘테이션에서 5시간 정도 걸리던 작업을 반자동 세그멘테이션 방법을 이용할 경우 최대 3분 이내에 분리 작업을 완료할 수 있으며 수치해석 실험 및 물리 실험에 이용할 수 있다.

• Tuberculosis and Respiratory Diseases
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• v.46 no.5
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• pp.654-661
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• 1999

Background : The upper respiratory tract is the primary target organ of various airborne pollutants and is easily accessible part of the respiratory tract, and also is the predominant structure where chronic cough originates. The nasal peak inspiratory flow(PIFn), which is the peak inspiratory flow via nose with nasal mask and spirometry, could be a reliable parameter of nasal obstruction. The validity of PIFn has been evaluated in several studies by assessing the correlation between PIFn measurements and other parameters of nasal air flow. This study was designed to show the reproducibility of PIFn, the difference of PIFn between patients with chronic cough and normal subjects, and the usefulness of PIFn in the evaluation of nasal obstruction in patients with chronic cough. Methods : PIFn was measured by spirometry with nasal mask, twice a day for 3 consecutive days in 7 young normal subjects to evaluate validity of the test. In 32 patients with chronic cough and 25 age-matched normal subjects, PIFn and pulmonary function test($FEV_1$, $FEV_1%$ pred, FVC, and FVC% pred) were measured at first visiting. Results : Values of PIFn, $FEV_1$, and FVC were nearly constant in 7 young normal adults. Patients with chronic cough were 32 (14 males and 18 females) and the mean age was $41.4{\pm}15.9$ years. Normal subjects were 32(22 males and 10 females) and the mean age was $39.8{\pm}18.6$ years. There was no significant difference of age and pulmonary function test between patients with chronic cough and normal subjects(p<0.05). The PIFn values in patients with chronic cough was significantly lower than those of normal subjects($2.25{\pm}0.68\;L/sec$ vs. $2.75{\pm}1.00\;L/sec$ ; p=0.02). The postnasal drip syndrome(PNDS) comprised the majority of patients with chronic cough(27). The PIFn in patients with PNDS was significantly lower than that of normal subjects (mean$\pm$SD ; $2.18{\pm}0.66$ vs. $2.75{\pm}1.00\;L/sec$, p=0.006). Conclusion : There was a significant difference of PIFn between patients with chronic cough and normal subjects. Among the patients with chronic cough, patients with PNDS showed the most significant difference with normal subjects in PIFn. The PIFn could be a useful parameter of nasal obstruction in patients with chronic cough, especially in patients with PNDS.

• Journal of Veterinary Clinics
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• v.28 no.4
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• pp.438-441
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• 2011

A 7-year-old castrated, domestic shorthair cat was presented with a 2-year history of chronic nasal discharge and sneezing. Upon presentation, bilateral mucopurulent nasal discharge and stertorous respiration were marked. Physical examination revealed a tachypnea. Oral examination was unremarkable and chest radiology was normal. Findings of nasal cytology and skull radiology were not specific and further imaging technique, endoscopic examination and histopathology was performed for a definite diagnosis. Fluid, and/or soft tissue opacity was found in bilateral nasal cavity, nasopharyngeal regions and right side tympanic bulla through the CT scan. No evidence of neoplasia was revealed. A rigid rhinoscopy, flexible bronchoscopy and otoscopy was used for the visualization of the lesions and tissue biopsy biopsy was performed for histopathology. On histopathological examination, the nasal mass consisted mainly of large numbers of plasma cells and lymphocytes. And the final diagnosis was lymphoplasmacytic rhinitis based on histopathologic examination. Long term management with oral cyclosporine (5 mg/kg, BID) was safe and successful in this cat. This is the first case report described clinical and diagnostic characteristic features of feline lymphoplasmacytic rhinitis and its clinical outcome using oral cyclosporine in Korea.

• Journal of the Korean Arthroscopy Society
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• v.8 no.1
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• pp.45-50
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• 2004

Purpose: The purpose of this study is to compare the outcome of operative results in the impingement syndrome of the shoulder with and without the stiffness. Material and Method: Seventy-six patients who had the impingement syndrome without stiffness were evaluated, and treated with the subacromial decompression and 24 patients who had the impingement syndrome with stiffness, were treated with the subacromial decompression and the manipulation. The average follow-up period was 32 months. Result: The impingement syndrome of the shoulder with stiffness was more severe in the preoperative pain and worse in ASES score than without stiffness. The postoperative pain and ASES score improved in the both group. The satisfactory groups were 67% in the group with stiffness and 80% without stiffness. The satisfactory rate was 83% in the group with stiffness and 93% without stiffness. The satisfactory groups with diabetes were 47% in the group with stiffness and 81% without stiffness. Forward elevation, exeternal rotation at the side and internal rotation improved in both groups postoperatively and there were no statistically significant differences postoperatively External rotation was restricted statistically in the group with stiffness. Conclusion: Although patients may not regain the full range of motion, the technique of manipulation followed by arthroscopic subacromial decompression offers good pain relief and satisfactory functional recovery for the impingement syndrome with stiffness. However preoperative counseling is necessary for the impingement syndrome combined with diabetes and stiffness due to poor out come.

• Journal of the korean academy of Pediatric Dentistry
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• v.32 no.3
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• pp.499-508
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• 2005

The purpose of this study were to evaluate the effect on the reversion of sedation induced by midazolam with flumazenil and to determine the plasma concentration of flumazenil according to the method of administration. Intranasal and intravenous flumazenil were administered to sedated health volunteers aged from 23 to 25 years, in doses typical of those used clinically to induce sedation with midazolam and for reversal with flumazenil. Objective assessment for degree of sedation and vital signs, plasma concentration were made for 2 hours period. 1. Systolic and diastolic blood pressure, $SpO_2$ were not changed by adminstration of flumazenil in sedated subject with midazolam, but pulse rate was increased temporarily. 2. Flumazenil showed the reversal of the sedative effect induced by midazolam regardless of administration methods. But intravenous administration showed more effect on the degree and the duration of reversion than intranasal administration with the exception of on set time. 3. Peak plasma concentration of flumazenil administered by intranasal route reached after 2 min and that of flumazenil administered by intravenous route was 4 min. Thus uptake of flumazenil did not showed any difference in accordance with the adminstration route. 4. Administration of flumazenil resulted in the temporary increase of midazolam plasma concentration.

• The Journal of Korean Institute of Next Generation Computing
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• v.15 no.5
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• pp.64-74
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• 2019

Although a non-rigid registration has high demands in clinical practice, it has a high computational complexity and it is very difficult for ensuring the accuracy and robustness of registration. This study proposes a method of applying a non-rigid registration to 3D magnetic resonance images of brain in an unsupervised learning environment by using a deep-learning network. A feature vector between two images is produced through the network by receiving both images from two different patients as inputs and it transforms the target image to match the source image by creating a displacement vector field. The network is designed based on a U-Net shape so that feature vectors that consider all global and local differences between two images can be constructed when performing the registration. As a regularization term is added to a loss function, a transformation result similar to that of a real brain movement can be obtained after the application of trilinear interpolation. This method enables a non-rigid registration with a single-pass deformation by only receiving two arbitrary images as inputs through an unsupervised learning. Therefore, it can perform faster than other non-learning-based registration methods that require iterative optimization processes. Our experiment was performed with 3D magnetic resonance images of 50 human brains, and the measurement result of the dice similarity coefficient confirmed an approximately 16% similarity improvement by using our method after the registration. It also showed a similar performance compared with the non-learning-based method, with about 10,000 times speed increase. The proposed method can be used for non-rigid registration of various kinds of medical image data.

• Proceedings of the KSLP Conference
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• 1996.11a
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• pp.96-96
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• 1996

구개인두부전증(velopharyngeal insufficiency, VPI)에 의한 발음이상을 평가하는 방법에는 여러 가지 방법이 개발되어 왔으나 비강측정기(nasometry)에 의한 비성수치(naslance score)의 측정과 spectrography에 의한 음향분석이 최근 널리 사용되고 있다. 본 연구에서는 실험적으로 유발한 VPI군의 음향학적 결과와 비강측정기의 결과를 정상군과 비교함으로써 VPI환자의 보다 정확하고 객관적인 평가의 방법과 지표를 얻고자 하였다. (중략)