• Anxiety and mood
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• v.13 no.2
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• pp.66-73
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• 2017

Objective : The purpose of this study was to examine the effects of adjunctive aripiprazole versus bupropion on specific symptoms of depression. Methods : Data were from 6-week, randomized, prospective, open-label multi-center study in 103 patients with major depressive disorders. Participants were randomized to receive aripiprazole (2.5-10 mg/day) or bupropion (150-300 mg/day) for 6 weeks. Change in four subscales of the 17-item Hamilton Depression Rating Scale (HAM-D17) that capture core depression symptoms was determined, and change in individual HAM-D17 items was also assessed. Changes in three composite subscales-anxiety, insomnia, and drive were also examined. Results : Within-group change in the four core subscales was large [effect size (ES)=1.30-1.47] and it was similar to that in the HAM-D17 total score. Differences between aripiprazole and bupropion were significant for each of the four core subscales and the HAM-D17 total score favored aripiprazole (p<0.001). On three composite scales, both treatments caused substantial changes in anxiety (within-group ES=1.10 (aripiprazole) vs. 1.00 (bupropion)], insomnia (ES=0.75 vs 0.50), and drive (ES=1.17 vs 1.15). Conclusion : This results suggested that both aripiprazole and bupropion adjunctive therapies with selective serotonin reuptake inhibitors resulted in significant and clinically meaningful changes in core symptom subscales for depression.

• Journal of Yeungnam Medical Science
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• v.9 no.1
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• pp.54-67
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• 1992

The author studied the mental status of 497 patients admitted in non-psychiatric wards and 42 patients diagnosed as mental disorders by DSM-III-R criteria and admitted in three general hospitals located in Pusan city, using NADS and PSCS. The assessment were obtained from October, 1991 to March, 1992 and the results as follows: The mean ${\pm}$ SD of Anxiety-Depression scores were $34.4{\pm}10.4$ in non-psychiatric patients and $50.0{\pm}18.3$ in psychiatric patients. The psychiatric group had significantly higher scores than non-psychiatric group. The mean ${\pm}$ SD of Psychosis scores were $3.9{\pm}4.4$ in non-psychiatric patients and $20.3{\pm}9.8$ in psychiatric patients. The psychiatric group had significantly higher scores than non-psychiatric group. In the psychosocial factors, dissatisfaction in family atmosphere and acquaintanceship with parellts(P<0.001, relatively), pessimistic in future, present and past self-images(P<0.001, relatively), and yes in previous psychiatric treatment of admission(P<0.01, relatively) had common significant relationships to Anxiety-Depression and Psychosis scores. There were correlationships between NADS scores and PSCS scores(${\gamma}$ = 0.74), past and present self-images(${\gamma}$ = 0.45), present and future self images(${\gamma}$ = 0.45), past and future self-images(${\gamma}$ = 0.34) and family atmosphere and acquaintanceship with parents(${\gamma}$ = 0.49). The regression analysis revealed that present self-image, acquaintanceship with parents, future self-image, past self-image, and family atmosphere, in order of significance were to be descriptive or predicable variances for Anxiety-Depression status. The discriminant analysis according to Anxiety-Depression scores showed that the cases of incorrect classification were 22 for non-psychiatric patient group and 2 for psychiatric patient group.

• Journal of Preventive Medicine and Public Health
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• v.25 no.1 s.37
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• pp.1-12
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• 1992

To assess the pattern of psychiatric symptoms and to evaluate the relationship between exposure related variables(duration of work and urinary hippuric acid concenturation) and psychiatric symptoms in organic solvent exposed workers, case control study of forty-two solvent exposed workers and ninethy-six non-exposed workers was conducted. The general health questionnaire 28(GHQ28) was administered to evaluate psychiatric symptoms and urinary hippuric acid concenturations was measured to estimate the present status of solvent exposure in exposed group and to estimate normal level in non-exposed group. The mean concenturation of urinary hippuric acid was significantly higher in exposed group (2.953g/creatinine g) than non-exposed group(0.395g/creatinine g) (P<0.01). The total positive rates of symptoms were significantly higher in exposed group(28.2%) than non-exposed group(17.5%)(P<0.05). The positive rates of symptoms for four sub-scales of GHQ28 in exposed group were in the order of somatic symptoms, anxiety, social dysfunction, depression and in the order of social dysfunction, anxiety, depression, somatic symptoms in non -exposed group. The positive rates of symptoms for somatic symptoms and anxiety were significantly higher in exposed group than non-exposed group (P<0.05) and the proportion of workers with six or more positive symptoms(dysthymic states) in exposed group were significantly higher than non-exposed group (P<0.01). After the effect of age, sex, level of income, level of education, and duration of work were controlled, the total score of GHQ28 was still significantly different between exposed and non-exposed group(P<0.01). In multipile logistic regression analysis on the dysthymic state, the odds ratio of level of income was statictically significant in both group. The odds ratios of exposure related variables such as duration of work and hippuric acid concenturations were not statistically significant but there was a tendency that exposure related variables had an affect on dysthymic state in exposed group. In future, continuous evaluation of psychiatric symptoms on organic solvent exposed workers and studies to detect the factors that affect on psychiatric symptoms are required.

• The Korean Journal of Vision Science
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• v.20 no.4
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• pp.483-495
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• 2018

Purpose : The purpose of this study is to analyze the factors affecting the mental health of students in the department of optometry by the gender and to provide differentiated help to student life and career guidance. Methods : Questionnaire for 132 students in the department of optometry in Chungcheong region was analyzed and mental health was compared and analyzed by the gender. In this study, a questionnaire by SCL-90-R was used, and all statistical information was statistically processed with a significance level of p<0.05 using SPSS 18.0 (SPSS 18.0 was used for processing statistical information with a significance level of p<0.05). Results : Students of the department of optometry presented mental health problems; somatization was 22.7%, psychasthenia was 28.3% and hostility was 12.8%. Depression and paranoia were 27.7% and 10.2% respectively, followed by interpersonal sensitivity, psychosis, phobia, and anxiety disorder with 14.7%, 10.4%, 5.9% and 17.4% respectively. Conclusion : About 28.7% of the students of the department of optometry students experienced somatization, psychasthenia or hostility due to negative mental health and female students ranked relatively higher in all variables than males. Therefore, it is judged that differentiated counseling and guidance in life will be needed for students based on their gender differences.

• Journal of Veterinary Clinics
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• v.27 no.2
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• pp.179-182
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• 2010

Cervical spondylomyelopathy (CSM) is rarely identified in small-breed dogs. Two neutered female Pekingese dogs (less than 5 kg of body weight) with primary complaints of neck pain and paretic gait were presented. These cases were diagnosed as CSM secondary to vertebral instability through cervical survey radiography, myelography, computed tomography (CT) and CT-myelography. The combinatory treatments of ventral slot decompression, cancellous bone graft and external coaptation were performed. Clinical condition of both dogs remarkably improved and no complications or recurrence occurred following the surgical procedures. In small-breed dogs with CSM, the combination of decompression through ventral slot and stabilization through bone fusion is an effective treatment.

• Anxiety and mood
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• v.11 no.1
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• pp.19-25
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• 2015

Objective : The current study investigated the prevalence and clinical characteristics of sexual exhibitionism and frotteurism, which was conducted for the first time in Korea. Methods : Among 568 total subjects (mean age $19.28{\pm}5.0$ year), 109 were victims of sexual exhibitionism (19.2%, VSE) of which 57 were females (91.9 percent) ; and 57 were victims of sexual frotteurism (10.9%, VSF) of which 57 were females (91.9%). The participants completed the self-reported scale for epidemiological and clinical characteristics. Results : Incident frequencies of above two times of VSE and VSF were 49 (50.0%) and 20 (32.3%), respectively. Incident locations of VSE were school/office 37 (33.3%), street 28 (25.6%), and near home 20 (18.3%). Also, incident locations of VSE were inside of bus 12 (19.3%), subway 12 (19.3%), subway/bus station 8 (12.9%), near home 8 (12.9%), and school/office 7 (11.3%). Notifying rate of VSE and VSF to the police were 7.3% and 0%, respectively. Also, notifying rate of VSE and VSF to family or friends were 72.5% and 58.1%, respectively Conclusion : These results suggested that VSE and VSF had a common prevalence, which could be different from behavioral and emotional characteristics of a control group ; and the victims were shown to require an active intervention by supportive social system.

• Anxiety and mood
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• v.6 no.1
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• pp.55-64
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• 2010

Objective : Depression is a significant and growing problem among college students. Depression contributes to numerous academic, social, and health problems, including suicide. This study surveyed depression awareness and the need for establishing a depression support program through Kyunghee University. Methods : We used the Kyunghee University Mail delivery system for college students to conduct this survey on depression and depression. Results : All of the students who responded to the survey, 41.86% reported that they had experienced depression. Among students experiencing depression, 27.27% experienced suicidal ideation, and 56.56% said they wanted to receive mental health counseling or treatment. All the respondents, 47.04% of respondents said they would to go to the external medical center, not school's internal counseling center of school, for such treatment. All the respondents, 73.75% said the student depression/suicide problem was serious. In addition, 71.34% of respondents required a depression support program. Conclusion : The university's depression support program needs to improve its accessibility by developing content focused on the early detection of, and improved awareness of, depression.

• Tuberculosis and Respiratory Diseases
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• v.62 no.1
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• pp.11-18
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• 2007

Background: Patients with chronic obstructive pulmonary disease (COPD) have often been reported to suffer from depression and anxiety possibly due to the exacerbation, hospitalization and mortality of COPD. However,scarce data are available in Korea. This study assessed degree of depression and anxiety, and evaluated the factors associated with depressive symptoms in COPD. Methods: The cross-sectional data on the lung function measurements, smoking behavior, body mass index (BMI), age, gender, depressive symptoms using Beck Depression Inventory (BDI) and anxiety using the State-Trait Anxiety Inventory (STAI) were evaluated in 72 outpatients with COPD and 50 controls without underling lung diseases from September, 2005 to October, 2006 in the Ewha medical center. Results: 1) The age, body mass index (BMI) and serum albumin levels were similar in the patients and controls. The BDI scores (16(0-37) vs. 12(1-30), p=0.001) and the prevalence of depression (36% vs. 6%, p<0.0001) were higher in the COPD patients than in the controls. In the COPD group, the prevalence of depression increased with increasing GOLD stage (p=0.008). The prevalence was 18%(4/22), in mild cases, 30%(6/20) in moderate cases, 52%(13/25) in severe cases and 60%(3/5) in very severe cases. 2) The SAI and TAI scores were higher in the COPD patients (44(20-67) and 47(20-66)) than in the healthy controls (39(26-65) and 44(33-90)). There were a significant correlation between the depression and anxiety scores (p<0.001). 3) A lower BMI, lower postbronchodilator $FEV_1$, current smoking behavior and severity of COPD were univariately associated with the depressive group in COPD, 4) while multivariate logistic analysis revealed only the severe-to-very severe group (OR 3.9, 95% CI 1.2 to 12.9) to be independently associated with depressive symptoms. Conclusion: COPD is strongly associated with depression and anxiety. Therfore, screening for psychological problems in COPD patients is essential, particularly in patients with severe-to-very severe COPD.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.2 no.1
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• pp.32-42
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• 1991

Spielbergers Test Anxiety Inventory(TAI) is a self-report scale which can measure the cognitive(Worry) and affective(Emotionality) components of test anxiety separately. After having administered it to 756 Korean middle school students, it was concluded that some of the items of TAI were not relevant for Koreans as they were. They have been revised on the basis of informations collected from interviews with Korean students. The Korean Form of TAI(TAI-K) consists of 25 items for primary school- and 35 for high school students. The Cronbach's ${\alpha}$ of the TAI-K and the test-retest reliability were proved(${\alpha}=.90,$ r=.78 for primary school students ; ${\alpha}=.94,$ r=.85 for high school students). General Anxiety Scale and Self-esteem Scale were used to prove its validity. test Anxiety correlates with general anxiety positively. while it correlates with self-esteem negatively.

• Stress
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• v.27 no.2
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• pp.199-204
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• 2019

Backgoround: This study aimed to examine the influence of anxiety sensitivity on task performance and physiological stress response, and to assess the effect of depression in this process for the youth population. Methods: We presented participants with an uncontrollable stress situation where they were required to perform mental arithmetic, based on the Montreal Imaging Stress Task (MIST). A total of 29 participants volunteered for this study. They completed the Anxiety Sensitivity Index-Revised and Patient Health Questionnaire-9 to measure their levels of anxiety sensitivity and depression. Two saliva samples, one before and one after the experiment, were collected to assess the change in cortisol levels as an index of physiological stress response. Results: Participants with high anxiety sensitivity showed lower performance on the mental arithmetic tasks and a significant increase in a salivary cortisol level, compared to those with low anxiety sensitivity. Furthermore, cortisol levels showed a remarkable increase where high anxiety sensitivity was coupled with depressed mood. In other hands, the levels of cortisol remained unchanged despite high anxiety sensitivity with low depressed mood. Conclusions: Our results confirm that the interaction between anxiety sensitivity and depression affects participants' task performance and stress response, as measured through behavioral tasks and physiological data with self-report indices. Also, through the physiological data, we examined that those who have a high level of anxiety sensitivity showed maladaptive responses under high stressful situation.