• Title/Summary/Keyword: 부정성 효과

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Effect of Ethane 1,2-Dimethane Sulfonate (EDS) on the Accessory Sex Organs in Adult Rats : A Histological Study (Ethane 1,2-Dimethane Sulfonate(EDS)가 성체 흰쥐의 부속 생식기관에 미치는 효과 : 조직학적 연구)

  • Lee, Won-Yong;Lee, Sung-Ho
    • Development and Reproduction
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    • v.13 no.2
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    • pp.105-114
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    • 2009
  • Ethane 1,2-dimethane sulfonate (EDS) is a well-known alkylating agent used as selective Leydig cell (LC) toxicant to create a testicular dysfunction model. Previous studies including our own clearly demonstrated the dramatic weight loss of the androgen dependent accessory sex organs such as epididymis, seminal vesicle and prostate gland in this 'LC knock-out' rats. The present study was performed to evaluate the effect of EDS administration on histological changes of the epididymis, seminal vesicle and prostate in adult rats. Adult male Sprague-Dawley rats (350$\sim$400 g B.W.) were injected with a single dose of EDS (75 mg/kg, i.p.) and sacrificed on weeks 0, 1, 2, 3, 4, 5, 6 and 7. Tissue weights (testis, epididymis, seminal vesicle and prostate gland) were measured. The histological changes of tissue were observed by a light microscopy using hematoxylin & eosin staining. Weights of the reproductive and accessory organs progressively declined after the EDS treatments (weeks 1, 2 and 3). After this, the decrease was stopped, then gradually returned to the normal levels. There was a partial (about 60%) recovery of the epididymis weight during weeks $6{\sim}7$. The cross section of epididymis revealed an increase in thickness of the epithelium during weeks $1{\sim}3$. In contrast, considerable reduction of epithelial thickness in seminal vesicle was observed during same period. Similarly, a reduction in thickness of prostate epithelial layer was found during weeks $1{\sim}3$, then it was back to normal thickness after week 4. Taken together, the present study demonstrated that the temporally induced androgen-deficiency by EDS treatment could result the prominent alterations in histology of the accessory sex organs. Further studies on the physiological and molecular regulation of these androgen-sensitive organs using EDS model will be helpful to understand the normal and pathological development and differentiation mechanism of these organs.

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Development of Theme-Based Integrated Unit in the Middle School Science and Analysis of it's Effects (중학교 과학수업을 위한 주제중심 통합단원의 개발 및 효과 분석)

  • Park, Soo-Kyong;Kim, Sang-Dal;Ju, Gook-Yong;Nam, Youn-Kyong
    • Journal of the Korean earth science society
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    • v.22 no.5
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    • pp.350-359
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    • 2001
  • The purpose of this study is to develop theme-based integrated science unit by the interdisciplinary approach and to analyze it's effects on the science achievement and the attitude towards science learning. 'Interaction' and 'Stability' were selected as the integrated themes, and the main concept and subconcept in relation to the themes were extracted from the four areas of science, and the learning contents were constructed in the integrated ways. While the main concept have relevance to subconcept in the interaction, the main concept have little relevance to subconcept in the stability. Therefore, the stability was to fit with middle school integrated science theme, but the interaction was not. The theme-based integrated science units developed was implemented in middle school, and the results are follows. First, the science achievement of group of theme-based integrated science teaching is significantly higher than those of group of traditional teaching. Second, the scores of the test of attitude toward science learning of the group of theme-based integrated science teaching is significantly higher than those of group of traditional teaching. Third, the students' perception of theme-based integrated science teaching was positive. The students have participation, interest, motivation in theme-based integrated science teaching, and students have difficulty in learning theme-based integrated science teaching.

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The Analysis of the Mediating and Moderating Effects of Perceived Risks on the Relationship between Knowledge, Feelings and Acceptance Intention towards AI (인공지능에 대한 지식, 감정, 수용의도 관계에서 위험인식의 매개 및 조절효과 분석)

  • Hwang, SeoI;Nam, YoungJa
    • The Journal of the Korea Contents Association
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    • v.20 no.8
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    • pp.350-358
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    • 2020
  • The objective of this empirical study is to examine the mediating and moderating effects of perceived risks on the relationship between knowledge, feelings and acceptance intention towards AI. Subjects in their teens to forties were surveyed and the final sample comprised 1,969 subjects. Data were analyzed using Mediation using Multiple Regression and Moderated Multiple Regression. Results showed that people's knowledge and feelings towards AI affected their acceptance intention of AI. Results also showed that the perceived risks of AI partially mediated and moderated the relationship between feelings and acceptance intention towards AI and moderated but not mediated the relationship between knowledge and acceptance intention towards AI. Overall, these results suggest that people's perceived risks of AI are associated more strongly with their feelings towards AI than their knowledge towards AI. Implications and directions for future research were discussed in relation to increasing general population's acceptance intention towards AI.

A Study on the Subjectivity of Consumers to Accept the Culture of Eating out through the YouTube Platform (유튜브 플랫폼을 통한 외식 문화 수용에 대한 소비자 주관성 연구)

  • Kim, Seong-Yong;Kim, Dong-Soo
    • The Journal of the Korea Contents Association
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    • v.20 no.9
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    • pp.414-423
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    • 2020
  • The purpose of This study is to investigate the effects of the acceptance of food culture through YouTube, one of the platforms that is currently being used, on consumers' perceptions, and to establish marketing effects that can be obtained from the acceptance of food culture through YouTube platform, Q-methodology was selected and exploratory research was conducted to analyze consumers' subjective perspectives. For this purpose, analysis was conducted by classifying statement cards by respondents, and Q-sorts were selected and composed by the Q-group, and after the statement was prepared through this, P-samples were selected and the Q-sorts obtained through classification work were analyzed through the Q factor analysis using the PC QUANL program. The analysis results were classified into four types: Type 1 [(N=6): Preferred Food and Responsibility Satisfaction Type], Type 2 [(N=3): Non-emotional Preferred Food Type, Type 3 [(N=14): Information Acquisition Preferred Food Type], Type 4 [(N=2): Undetermined Type], etc. Each subjective opinion from these analyses will be helpful for various studies in the future, and it will be used as a reference for YouTube-related marketing and consumer restaurant culture acceptance in the future.

Characterization of Microbial Pathogen Bacillus thuringiensis Isolates from Soil Against Mosquito and Silkworm Larvae (II) (토양에서 분리한 살충성 Bacillus thuringiensis의 모기와 누에 유충에 대한 독성효과 (II))

  • Lee, Hyung-Hoan;Yoo, Bo-Rim;Kim, Young-Joo;Won, Nam-Hi;Kim, Hak-Chun
    • Korean Journal of Microbiology
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    • v.31 no.1
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    • pp.17-21
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    • 1993
  • Eight strains of Bacillus thuringiensis were isolated from soil in Korea and characterized. The isolates were named HL-24, HL-25, HL-33, HL-34, HL-35, HL-38, HL-39, HL-40. Strains HL-24 and HL-25 produced irregular parasporal crystals, HL-33 and HL-35 produced bipyramidal crystals, and others were round form in their cells. The biochemical characteristics of the eight isolates were only minor different in specific characteristics to the known serotypes of Bacillus thuringiensis. The HL-25, HL-33 and HL-34 strains showed resistances to cephalothin, colistin and penicillin G, and HL-39 and HL-40 strains were resistant to penicilin G. The strains of HL-24, HL-25, HL-33 and HL-34 were toxic to Bombyx mori lavae and HL-24, HL-25, HL-38, HL-39 and HL-40 strains killed Culex pipiens 3rd instar larvae. The HL-24 and H25 strains showed lethal activity against two kinds of the larvae, however lethality against mosquito larvae was low.

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Development of functional lighting fixture and Experiment of to the Biological effects (기능성 반사판 조명기구 개발 및 효능 실험)

  • Kim, Chang-Hwan;Kim, Hyeon-Soo;Chee, Chol-Kon
    • Proceedings of the Korean Institute of IIIuminating and Electrical Installation Engineers Conference
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    • 2004.11a
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    • pp.203-208
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    • 2004
  • We are living now under the bad air pollition contained the many plus(+)ion produed by the exhaust gases from automobil and Industrial plant. To be refreshe those air pollution. We developed the funtional lighting fixture which emit the lighting, negative(-)ion and Infraredray. The negative(-)ion and Infraredray refresh the air pollition and will arise nature healing power lot the human body and activate the body cell, and makes the good blood circulation and then we had the experiment to the Biological effect by the funtional lighting fixture.

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Landuse Information System Construction and Landuse Pattern (토지이용정보체계구축 및 토지이용유형화에 관한 연구)

  • 이근상;임승현;조기성
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.17 no.1
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    • pp.1-10
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    • 1999
  • Landuse information is base data being applied as common database in the process of executing urban project service and is very available. But, the progress of business on landuse information building is deficient yet. In this study, we'd like to deal with landuse information projet that is the base of urban project, many landuse information building and the method of extraction of efficient second-information. Also, we built system to apply actively landuse information for urban projectors. And, we'd like to present the model on urban landuse classification system that wouldn't be standard yet by studying the method of urban landuse pattern using landuse in-formation being built. Also, we can evaluate if the model of urban landuse pattern comes up to present landuse. We can expect it is a base data by extracting unsuitable area from present landuse efficiently when we construct landuse project.

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A Real Scale Experimental Study for Evaluation of Permissible Shear Stresses on Vegetation Mats (식생매트 허용 소류력 평가를 위한 실규모 실험 연구)

  • Lee, Du Han;Kim, Dong-Hee;Kim, Myounghwan;Rhee, Dong Sop
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.13 no.12
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    • pp.6151-6158
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    • 2012
  • By the activation of environment-friendly river works, application of vegetation mats is increasing, however, evaluation techniques for hydraulic stability of vegetation mats are not presented. This study is conducted to develop the objective test method for vegetation mats. Two kind of vegetation mats are tested by the real scale experiments, and hydraulic quantities are measured and analyzed to evaluate acting shear stresses. Roughness and shear stress are evaluated by 1 D non-uniform model. After each tests, changes in mat surfaces and sub-soil are evaluated, and from these evaluation, 3 types of mat surface damages and 2 types of sub-soil damages are presented. In the study, the case in which some damages in mat surface don't cause loss of sub-soil, is presented to be in the stable condition. Appling this stable condition and acting shear stresses, permissible shear stresses of vegetation mats are evaluated, and the results show that the reinforced mat with wire netting has more permissible shear stress.

Surgical Management for Chronic Atrial Fibrillation (만성 심방세동에 대한 외과적 치험 4례)

  • 강경훈;김철환;김병열
    • Journal of Chest Surgery
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    • v.31 no.1
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    • pp.59-65
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    • 1998
  • Atrial fibrillation is the most common of all cardiac arrhythmias. It is associated with significant morbidity and mortality and is frequently resistant to medical therapy. On the experimental and clinical study, the presence of macroreentrant circuits and the absence of either microreentrant circuits or evidence of atrial automaticity suggests that atrial fibrillation should be amenable to surgical ablation. The results of the maze III procedure are associated with a higher incidence of postoperative sinus rhythm, improved long-term sinus node function, fewer pacemaker requirements, less arrhythmia recurrence, and improved long-term atrial transport function. We had experienced 4 patients with chronic atrial fibrillation. For the first time, Hioki procedure had been performed in the first patient with ASD and atrial fibrillation, regular sinus rhythm showed on postoperative EKG, but junctional rhythm and bradycardia developed postoperative 3 years. The maze III procedure for the rest with mitral valvular disease and atrial fibrillation had been done, followed by regular sinus rhythm for 2 patients and atrial fibrillation for 1 patient, managed with amiodarone, on immediate postoperative state. Echocardiogram documented good contraction of right atrium and hardly contraction of left atrium for 2 patients with regular sinus rhythm postoperative 3 months.

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Comparison Impulse Response Method with Method of Characteristics for Transient Analysis in a Pipeline System with hydraulic devices (수리구조물이 부착된 관망에서의 천이류 해석에 대한 임펄스응답법과 특성선방법의 비교 연구)

  • Song, Yong-Seok;Jang, Il;Kim, Sang-Hyun
    • Proceedings of the Korea Water Resources Association Conference
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    • 2007.05a
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    • pp.1179-1183
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    • 2007
  • 관망 내에서 흐름의 연속 방정식과 운동량 방정식을 상 미분으로 전개하여 해석한 특성선 방법은 주로 가압 관망체계(Pressurized Pipeline System)에서의 부정류 해석(Unsteady Analysis)에 사용 된다. 그러나 이특성선 방법은 천이류 해석을 위한 관망 재구성 과정에서 Courant수 조건의 만족을 위한 관의 재배열에 천문학적인 계산용량과 시간이 필요하다는 단점이 있다. 이는 현장 적용 시 압력파 전파속도의 불확실성과 연계되어 상당한 장해요소가 되고 있다. 이에 대안적인 방법으로서 임펄스응답법이 개발되었다. 이는 경계지점에서 복소수 유량에 대한 복소수 수두의 비율로써 정의된 관망에서의 수리임피던스를 역퓨리에 변환에 적용하여, 주파수 영역의 수치를 시간 영역으로 변환하여 응답함수를 산출한 후, 산출된 응답함수와 구해진 경계지점에서의 유량과의 적분을 통하여 임의의 지점에서의 수두 및 유량을 계산하는 방법이다. 임펄스 응답법은 관 부속물관의 특성을 기술하는 수학적 표현의 난해함으로 인해 지금까지는 단일관에 대한 연구에만 국한되어 왔다. 본 연구에서는 임펄스응답법을 수리구조물이 부착된 관망에 적용하여 다양한 조건에서 천이류 분석을 시행하였다. 즉, 에어챔버 및 서지탱크와 같은 수리구조물을 각각에 대한 수리임피던스를 구하고, 가지관 및 통합 관성항으로 취급하여 수리구조물을 처리하였다. 그리고 이러한 결과를 특성선방법과 비교하여 그 적절성을 검증하였는데, 특성선 방법에 의한 모의 결과와 비교하였을 때, 일치하는 결과를 나타내었다. 임펄스응답법에 의한 모의 결과에서 감쇄효과를 과대평가하는 경향이 관찰되었다. 이는 임펄스 응답법의 가정에 기인한 것으로써 난류 상태의 흐름에서 상당한 불일치를 가져올 수 있으나, 수리 구조물에 의한 수격압이 감쇄되는 과정에서 대부분 흐름이 층류 상태로 전환된다고 가정 할 때는 상당한 적용성이 있다. 본 연구는 수리구조물이 부착된 관망의 해석함에 있어서 임펄스응답법의 적용이 가능함을 보였고, 이는 보다 복잡한 관망에서의 천이류 해석이 가능함을 시사한다.

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