• Title/Summary/Keyword: 부신전이

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A Case of Recurrent Papillary Thyroid Carcinoma with Adrenal Metastasis (재발 유두 갑상선암의 부신전이 1예)

  • Kim, Chang-Woo;Yun, Ji-Sup;Lee, Yong-Sang;Nam, Kee-Hyun;Chung, Woong-Youn;Hong, Soon-Won;Park, Cheong-Soo
    • Korean Journal of Head & Neck Oncology
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    • v.23 no.1
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    • pp.50-53
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    • 2007
  • Adrenal metastasis from papillary thyroid carcinoma is extremely rare. We present herein a patient with adrenal metastases from recurrent papillary carcinoma of the thyroid. A 54 year-old woman had received a total thyroidectomy and postoperative radioactive iodine therapy for locally advanced papillary thyroid carcinoma. One year after initial surgery, distant metastases to multiple organs including right cervical lymph nodes, left upper lung, left 2nd and 3rd ribs, 2nd thoracic vertebra and left adrenal gland were found by 18-FDG-PET-CT whole body scan. She underwent right modified neck dissection, partial resection of left 2nd and 3rd ribs, posterior arch of 2nd thoracic vertebra, left upper lobectomy of lung, and left adrenalectomy. On histologic examination, metastases to the left adrenal gland and cervical lymph nodes were papillary thyroid carcinomas, while other metastatic sites turned out to be anaplastic thyroid carcinomas. Despite aggressive surgery and postoperative adjuvant therapy, her general clinical conditions were getting worse day by day due to regrowing of the anaplastic thyroid carcinomas. To our knowledge, this is the first case reported in Korea.

Delayed Contrast-enhanced Computed Tomography for Adrenal Masses in 3 Dogs (개 부신종양의 지연형 조영증강 전산화단층촬영 적용 3증례)

  • Lee, Jeo-soon;Yoon, Junghee;Oh, Hyun-jung;Kim, Bo-eun;Kim, Wan-hee;Youn, Hwa-young;Choi, Min-cheol
    • Journal of Veterinary Clinics
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    • v.32 no.3
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    • pp.263-267
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    • 2015
  • Three dogs having adrenal masses detected on ultrasonographic examination were underwent computed tomography (CT) for surgery. After adrenalectomy, each mass was diagnosed pheochromocytoma with myelolipoma, adrenocortical carcinoma and adrenal adenoma through histopathology. Five minutes were used to get delayed enhanced CT images. Attenuation value was measured in each mass and the absolute and relative percentage of enhancement washout were calculated.

Clinical Presentation of Paraganglioma in Orthopaedics - Report of Two Cases - (정형외과 영역에서의 부신경절종의 임상 양상 - 2례 보고 -)

  • Lee, Sang-Lim;Oh, Joo-Han;Lee, Sang-Hoon;Kim, Han-Soo;Kim, Hyung-Ho;Kim, June-Hyuk
    • The Journal of the Korean bone and joint tumor society
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    • v.11 no.1
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    • pp.94-99
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    • 2005
  • Paraganglioma is a neoplasm consisting of sympathetic neuroendocrine cells, which arise from neural ectoderm of extra-adrenal paraganglia. It often occurs in thyroid, carotid body, mediastinum, lung, duodenum, the retroperitoneal area and periaortic area. Malignant paraganglioma is defined not by the histological diagnosis, but by spread to regional lymph nodes or distant metastasis. Rare bone metastasis mostly occurs in the base of skull or spine, and even it rarely metastasizes to pelvis or femur. We would like to report two cases of paraganglioma; one in the subcutaneous fat layer that was mistaken for a vascular tumor, and the other in the retroperitoneal space with early bone metastasis.

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Anatomical Variations Encountered during Adrenal Venous Sampling: A Report of Three Case Series and Review of Literature (부신정맥채혈술 중 발견된 해부학적 변이들: 3건의 증례 보고 및 문헌 고찰)

  • Juyoung Pak;Hyoung Nam Lee;Myung Sub Kim;Hyerim Park
    • Journal of the Korean Society of Radiology
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    • v.85 no.2
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    • pp.456-462
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    • 2024
  • Primary aldosteronism is a group of disorders in which the autonomous secretion of aldosterone is associated with hypertension and hypokalemia. It is crucial to determine the laterality of aldosterone hypersecretion because treatment options differ accordingly. Adrenal venous sampling (AVS) is considered the most reliable method for assessing the laterality of primary aldosteronism. This procedure is often technically challenging because of the small size and varied locations of the adrenal veins. A better understanding of anatomical variations and careful review of imaging studies would improve sampling success. This report presents three cases of anatomical variations encountered during AVS.

A Case of Recurred Paraganglioma of the Anterior Mediastinum A Case of Recurred Paraganglioma of the Anterior Mediastinum - A Case Report - (재발된 전종격동 부신경절종 치험 1례)

  • 김주현;김두상;성숙환;김영태
    • Journal of Chest Surgery
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    • v.31 no.2
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    • pp.198-202
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    • 1998
  • The recurrence of an anterior mediastinal mass was discovered incidentally on the chest film for an asymptomatic 72-year-old female. She underwent the mass resection at the same site in 1989 and was diagnosed as a paraganglioma of the anterior mediastinum. She had poorly controlled hypertension which was converted into normal blood pressure after the first operation. During the follow up, the catecholamine levels were within normal limits, and there were no evidence of recurrence of the tumor. However, 6.3 years later, the mass recurred at the same anterior mediastinum. The patient had no hypertension and catecholamine levels were still within normal limits. The recurring mass was successfully removed and had the same histological findings - recurring paraganglioma.

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$^{131}I-MIBG$ Scintigraphy in Double Focuses Pheochromocytoma (이중병소를 가진 갈색종의 $^{131}I-MIBG$ 신티그라피)

  • Kim, Hak-Hee;Chung, Soo-Kyo;Kim, Sung-Hoon;Park, Young-Ha;Bahk, Yong-Whee;Shinn, Kyung-Sub
    • The Korean Journal of Nuclear Medicine
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    • v.26 no.1
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    • pp.151-154
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    • 1992
  • 갈색종은 비교적 드문 종양으로 다발성으로 생기는 경우는 더욱 드물다. 갈색종은 수술로 90%이상 완치 가능한 질환이므로 수술전 종양의 위치와 범위를 정확히 확인하는 것 이 매우 중요하다. 저자들은 최근 파동하는 고혈압을 주소로 내원한 33세 남자환자에서 복부전산화 단층촬영술상 우측부신의 종양만을 확인할 수 있었으나, $^{131}I-MIBG$ 신티그라피에서는 우측 부신의 병소외에 골반강 내에 또다른 병소가 발견되어 골반강 전산화 단층촬영술을 추가로 시행하였고 이어 수술로써 확진된 이중병소의 갈색종 1예를 보고하는 바이다.

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A Case of Childhood Cerebral Form Adrenoleukodystrophy with Novel Mutation in the ABCD1 Gene (새로운 ABCD1 유전자의 돌연변이를 가지는 소아 대뇌형 부신백질이영양증 1례)

  • Shin, Young-Lim
    • Journal of The Korean Society of Inherited Metabolic disease
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    • v.12 no.1
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    • pp.49-53
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    • 2012
  • X-linked adrenoleukodystrophy (ALD) is a rare inherited metabolic disease which results in impaired peroxisomal ${\beta}$-oxidation and the accumulation of very long chain fatty acids (VLCFA) in the adrenal cortex, the myelin of the central nervous system, and the testes. X-linked ALD is caused by mutations in the ABCD1 gene encoding an ATP-binding cassette transporter superfamily located in the peroxisomal membrane. This disease is characterized by a variety of phenotypes. The classic childhood cerebral ALD is a rapidly progressive demyelinating condition affecting the cerebral white matter before the age of 10 years in boys. We report the case of a 8-year-old with childhood cerebral X-linked ALD who developed inattention, hyperactivity, motor incoordination and hemiparesis. We diagnosed ALD with elevated plasma very long chain fatty acid level and diffuse high signal intensity lesions in both parieto-occipital white matter and cerebellar white matter in brain MRI. We identified a novel c.983delT (p.Met329CysfsX7) mutation of the ABCD1 gene. There is no correlation between X-ALD phenotype and mutations in the ABCD1 gene. Further studies for searching additional non-genetic factor which determine the phenotypic variation will be needed.

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Surgical Treatment for Primary Pulmonary Paraganglioma - A case report - (폐에 발생한 원발성 부신경절종의 수술치험 - 1예 보고 -)

  • Lee Choong-Won;Bang Jung-Heui;Roh Mee-Sook;Kim Ki-Nam;Choi Phil-Jo
    • Journal of Chest Surgery
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    • v.39 no.9 s.266
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    • pp.718-721
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    • 2006
  • We describe the case of primary pulmonary paraganglioma in a 37-year-old woman who presented recurrent, severe cough. Computed tomography revealed a lobulated inhomogeneous enhanced mass with endobronchial protruding lesion suspected to be lung neoplasm, located in the upper lobe of the left lung. Bronchoscopic biopsy showed chronic inflammation with granulation tissue which was not in accord with the radiologic findings. Subsequently, a left lower sleeve lobectomy was peformed. Histological analysis of the resected tumor proved to be compatible with pulmonary paraganglioma. Primary pulmonary paragangliomas are very uncommon tumors. So we report this case with literature review.

A Case of Recurrent Pheochromocytoma Diagnosed by $^{131}I$-MIBG Scintigraphy ($^{131}I$-MIBG Scintigraphy로 진단된 재발성 갈색 세포종 1예 - Report of A Case -)

  • Jung, Dong-Sung;Lee, Gwi-Lae;Han, Chang-Wan;Cho, Young-Sam;Park, Woon-Sik;Jung, Yoon-Hyung;Joo, Hong-Don;Park, Sung-Ki;Kim, Sung-Hwan;Kim, Jung-Lyeu;Moon, Dae-Hyuk
    • The Korean Journal of Nuclear Medicine
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    • v.28 no.3
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    • pp.402-406
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    • 1994
  • Pheochromocytomas are catecholamine-producing tumors of neuroectodermal origin, and may arise wherever chromaffin cells are located. They are rare but potentially lethal and amenable to surgical cure. Once a clinical diagnosis has been established, localization becomes of importance to direct surgical approach. MIBG scintigraphy is the initial localizing procedure of choice, due to its ability to screen the entire body, especially in the detection of extraadrenal and recurrent pheochromocytoma. A case of recurrent extraadrenal pheochromocytoma diagnosed by $^{131}I$-MIBG scintigraphy is presented with review of the literature.

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Clinical Picture of Adrenal Insufficiency-associated Hypotension in Preterm Infants (조산아에서 발생하는 부신기능부전과 연관된 저혈압의 임상상)

  • Choi, Eun-Jin;Sohn, Jin-A;Lee, Eun-Hee;Lee, Ju-Young;Lee, Hyun-Ju;Chung, Hye-Rim;Lee, Jin-A;Choi, Chang-Won;Kim, Ee-Kyung;Kim, Han-Suk;Kim, Beyong-Il;Choi, Jung-Hwan
    • Neonatal Medicine
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    • v.18 no.1
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    • pp.82-88
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    • 2011
  • Purpose: This study aims to describe the clinical characteristics of adrenal insufficiency-associated hypotension in preterm infants and the effects of hydrocortisone therapy on their cardiovascular system and serum electrolytes. Methods: Twelve preterm infants less than 32 gestational weeks admitted to neonatal intensive care unit (NICU) of the Seoul National University Bundang Hospital from January 2007 to August 2009 with clinical and laboratory findings suggestive of adrenal insufficiency were analyzed retrospectively. Results: Gestational age was 27.8${\pm}$2.5 weeks and birth weight was 1,110${\pm}$307 g. Postnatal age, postmenstrual age, weight at the onset of adrenal insufficiency-associated hypotension were 19${\pm}$7 day, 30.6${\pm}$2.4 weeks, 1,285${\pm}$365 g. In preterm infants who showed vasopressor resistance, intravenous hydrocortisone was started with a stress dose of 4 mg/kg/day, maintained for 2.2${\pm}$0.7 days, and then tapered. Serum cortisol concentration before hydrocortisone administration was 11.6${\pm}$4.1 mg/dL. Mean blood pressure increased from 25.0${\pm}$5.4 mmHg to 35.0${\pm}$5.3 mmHg, 38.3${\pm}$8.0 mmHg and 41.9${\pm}$6.5 mmHg at time of hydrocortisone administration and 2, 4 and 6 hours after hydrocortisone administration. Urine output increased from 0.9${\pm}$0.6 mL/kg/hr to 4.1${\pm}$3.4 mL/kg/hr. Twelve hours after the administration of hydrocortisone, dopamine requirement decreased from 11.0${\pm}$2.9 $\mu$g/kg/min to 8.0${\pm}$2.3 $\mu$g/kg/min, and to 5.5${\pm}$3.4 ${\mu}g$/kg/min after 24 hours. Serum sodium concentration was increased from 130${\pm}$4 mEq/L to 136${\pm}$4 mEq/L, serum potassium concentration was decreased from 6.1${\pm}$1.1 mEq/L to 4.6${\pm}$0.6 mEq/L before and 12 hours after hydrocortisone administration. Conclusion: In preterm infants with adrenal insufficiency-associated hypotension, hydrocortisone administration improved blood pressure and urine output, decreased vasopressor requirement, and normalized serum electrolyte abnormalities.