• Korean Journal of Culture and Social Issue
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• v.21 no.2
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• pp.119-130
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• 2015

This study is aimed to analyse the causes and characteristics of suicide in jeonbuk region using psychological autopsy. Psychological autopsy is a technique to get comprehensive analysis on suicidal death by collecting data from interviewing suicide victim's family, relatives, and friends added with additional data of police report, hospital records, and suicide victim's lifetime records for objective evidence. For the data from 42 cases(male 24, female 18) of suicides that occurred between May 2013 and April 2014 with agreement for psychological autopsy, we analyzed a survey that recorded by interviewers who had a consultation based on half-structured psychological interview panel. As the result, out of 42 cases, 30(71%) had previous suicidal attempts and 21(50%) had a family history of suicides. Psychiatric disorders(38%) was the most common cause of suicide followed by interpersonal problems(31%). Among psychiatric problems, depressive disorder was the most common. many suicide victims had previously received psychiatric treatments but discontinued the therapy later on. The results showed that suicide is strongly related to mental disorders and psychiatric therapy should be continued until full recovery. Preventive efforts should focus on persons who have a history of previous suicidal attempts and have a family history of suicide. Implications of these findings are discussed and directions for future research are advanced.

• Korean Journal of Veterinary Pathology
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• v.6 no.2
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• pp.79-81
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• 2002

1. 동물; 돼지, 80일령. 2. 부검소견; 폐장의 상단하방(cranioventral) 부위에서 경화소(consolidation)이 관찰되었다. 3. 조직소견; 폐장의 폐포강(alveolar space)와 기관지 내강에 염증세포의 침윤이 관찰되었다. 폐포강에 침윤된 염증세포는 핵이엽인 호중구로 구성되어 있고 간혹 대식세포도 관찰된다. 기관지 내강에 침윤된 염증세포는 호중구로만 구성되어 있다. 4. 진단; Bronvhopneumonia, acute, severe, suppurative. 5.원인체; Pasteurella multocida. (중략)

• 월간산업보건
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• s.190
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• pp.45-46
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• 2004

• Proceedings of the Korean Society of Applied Pharmacology
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• 1996.04a
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• pp.200-200
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• 1996

간재생 및 만성 간질환모델에 대한 인진호 추출분획의 간장 약효검색 방법 1. 간세포 재생능력에 대한 효과 : SD계 수컷 흰쥐(체중 300-350g)를 마취하에서 복부정중선을 따라 개복후 간의 중앙엽 및 좌측엽을 절제하여 봉합하고 수술조작을 끝낸 추 4시간, 익일부터 7일간 오후 5시에 약물을 경구투여하고 마지막투여 후 20시간 절식, 부검하여 간재생률 및 BSP 정체율을 측정하였다. 2. $CCl_4$ 만성간장해 모델에 대한 효자 SD계 수컷 흰쥐(체중 200-250g)에 $CCl_4$ : olive oil 40%용액을 0.5 $m\ell$/kg b.wt. 용량으로 6일간 결구투여 한 후 7일째부터 매일 시험약물을 $CCl_4$ 혼합액 투여 4시간전 및 4시간후에 2회 경구투여하였으며 이 조작을 8일간 하고 마지막 투여 24시간 후에 부검하여 혈액내 ALT 및 AST치, 간조직내 total protein, triglyceride 및 hydroxyproline 양을 측정하였으며, 간중량도 측정하였다. 3. 약물투여 음성대조 : 1% CMC-Na 용액(10$m\ell$/kg b.wt.) 양성대조 : silymarin(25mg/kg), DDB(37.5mg/kg) 인진호추출분획 : KP(180mg/kg), PS-1(300mg/kg), PS-2(300mg/kg), EE (500mg/kg ), HH(640mg/kg), BE(1500mg/kg)

• Journal of Korean Biological Nursing Science
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• v.16 no.3
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• pp.211-218
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• 2014

Purpose: This research was designed to investigate the effects of forensic education and autopsy attitude of nursing students. Methods: Data on autopsy attitude were determined and collected by means of a self-reporting questionnaire including 14 questions on perception of a need for an autopsy and 11 questions on resistance to autopsy, the respondents being 846 nursing students. The collected data were analyzed by means of an independent t-test with one-way ANOVA in an SPSS WIn 18.0 program. Results: The perception of a need for an autopsy was 4.06 on average and resistance to autopsy was 2.64 on average. The nursing students taking a forensic course showed a relatively higher level of perception of the need for an autopsy (t=-5.63, p <.001) than those not attending such a course (t=2.93, p <.001). Perception of the need for an autopsy and resistance to autopsy show a negative correlation (r=-.382, p=.003). Conclusion: A forensic medicine course raises the level of perception of the need for an autopsy by nursing students and reduces the level of resistance to autopsy.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.25 no.3
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• pp.121-127
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• 2014

Recently, local governments and suicide prevention centers have been trying to implement psychological autopsy. This effort has focused on adult suicide so far ; however, there are some difficulties in its application to adolescent suicide. Therefore, in this study, psychological autopsy studies of Korea were reviewed, and a methodology for adolescents' psychological autopsy was suggested. For the effective performance of the psychological autopsy in adolescent suicide, cooperation with each area of the government and implementation of bodies is necessary. In addition, the central system, which disseminates the standardized interview to the community and manages the data nationwide, should be prepared. Also, in order to improve the accuracy of diagnosis and to obtain various types of information, a structured interview should be adopted as the psychological autopsy, as well as considering the use of social media. Investigation of specific risk factors for adolescent suicide through psychological autopsy can enable determination of the intervention point for effective suicide prevention.

• Journal of the Korean Data and Information Science Society
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• v.10 no.1
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• pp.215-222
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• 1999

It is well known to use scalp hair as a signal of strengths of heavy metals contamination. In this paper, using the multivariate methods we examine the relationship between strengths of cadmium and mercury in scalp hair and cerebellum, cerebrum, heart, kidney, liver, lung and spleen from 61 korean autopsy subjects. As a result, there is statistically singnificant relationship between strengths of mercury contamination in scalp hair and secondary contaminated organs.

• The Journal of Internal Korean Medicine
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• v.35 no.1
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• pp.37-49
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• 2014

Objectives & Methods : The objective of this study was to evaluate the single oral dose toxicity of Chongmyung-tang (CMT) in ICR mice. Korean traditional herbal prescription CMT has traditionally been used as a neuroprotective for treatment of learning disability and memory improvement. CMT, lyophilized aqueous extracts (yield=9.7%) were administered to female and male mice with oral dose of 2,000, 1,000 and 500 mg/kg (body weight) according to the recommendation of Korea Food and Drug Administration (KFDA) Guidelines. Animals were monitored for mortality, changes in body weight, clinical signs and gross observation during 14 days after administration upon necropsy; organ weight and histopathology of 14 principle organs were examined. Results : We could not find any CMT extracts treatment related mortalities, clinical signs, changes in body and organ weight, or gross and histopathological observations against 14 principle organs up to 2,000 mg/kg in both female and male mice, except for some accidental sporadic findings which did not show any obvious dose-relations and most of which also demonstrated in both the female and male vehicle control mice in this experiments. Conclusions : Based on the results of this experiment, the 50% lethal dose ($LD_{50}$) and approximate lethal dose (ALD) of CMT extracts after single oral treatment in female and male mice can be considered to be over 2,000 mg/kg, and is likely to be safe in humans.

• Journal of Veterinary Clinics
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• v.13 no.2
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• pp.195-197
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• 1996

제주도에 서식중인 흑기러기(Branta bernicla)가 식욕감퇴, 점진적인 수척, 호흡촉박 등을 나타내다 폐사하였다. 부검소견으로서는 폐 및 복부기낭에 다수의 위약한 흰색-황색 결절이, 병리조직학적검사결과 괴사병소에 균사와 Aspergillus의소포가 확인되었다. 배양결과 Aspergillus fumigatus 감염증으로 진단된 국내 최초의 보고로 생각된다.

• Environmental Mutagens and Carcinogens
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• v.11 no.2
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• pp.118-133
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• 1991

신생랫드를 이용한 다장기 발암모델의 전암단계 병변에서 간장의 GST-P 활성도와 발암 과정에 영향을 미치는 phenobarbital (PB)의 발암촉진효과 및 병리조직학적 소견을 관찰하였다. 신생랫드를 150마리 3군으로 나누어 diethylnitrosamine (DEN : 100mg/kg,i,p.), N-me-thyl-N-nitrosourea (MNU : 20mg/kg,i,p.), N-bis(2-hydroxypropyl)nirtosamine(DHPN : 0.1% D. W)을 각각 0, 3, 6 주에 투여하였다. 또한 PB (0.5% in basal diet)를 7주부터 계속 투여하여 8, 12, 20주에 경시적인 부검을 실시하였다.