• Title/Summary/Keyword: 복합위험지수

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THE STUDY ON RELATIONSHIP BETWEEN PSYCHOPATHOLOGY AND NEUROLOGICAL FACTORS IN CHRONIC EPILEPTIC CHILDREN (경련 질환 환아의 정신병리와 신경학적 요인과의 관계에 대한 연구)

  • Kim, Bung-Nyun;Cho, Soo-Churl;Hwang, Yong-Seung
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.7 no.1
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    • pp.92-109
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    • 1996
  • The objectives of the present study were to provide comprehensive assessment of the impact of epilepsy on the psychological well-being of children with epilepsy and to identify the neurological factors associated with the psychopathology. The participant patients were recruited from the population of children and adolescent aged 7 to 16 attending the OPD of department of pediatric neurology in Seoul National University Hospital in Korea. We exclude mental retardation, pervasive developmental disorder and brain organic pathology. As control group, formal students were chosen and their sex, age, achievement, socioeconomic status were matched to patients. The first author interviewed the children and their family members and obtained the developmental history and family information. We used the following 10 scales for assessing psychological and behavioral problems in patients and their family member. The scales were standardized and their validity and reliability were confirmed before. Parent rating scales : Yale children's inventory, Disruptive behavior disorder scale, Parent's attitude to epilepsy questionnaire, Family environment scale, Symptom check-list-90 revision, Children behavior check-list. Children's self rating scales : Children's depression inventory, Spielberger's state-trait anxiety anxiety, Piers-Harris self-concept inventory and Self-administered Dependency questionnaire for Mother. The result showed the risk factors associated depression were early onset, complex partial seizure, lateralized temporal focal abnormality on EEG, Drug polypharmacy, high seizure frequency and sick factors associated anxiety were old age of patient, lateralized temporal focal abnormality EEG, Drug polypharmacy, high seizure frequency. Also the result of this present study indicated that risk factors associated oppositional defiant disorder, conduct disorder and attention deficit hyperactivity disorder were young age, male, early onset, lateral temporal EEG abnormality and high seizure frequency. According to these results, common risk factors associated psychological and behavioral problems were lateralized EEG temporal abnormality, high seizure frequency in neurological factors.

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The influence of internet addiction on health behavior, sexual behavior and mental health of college student (대학생의 인터넷 중독이 건강행동, 성행동, 정신건강에 미치는 요인)

  • Nam, Mun-Hee;Kim, Jeoung-Mi
    • Journal of Digital Convergence
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    • v.12 no.4
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    • pp.367-378
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    • 2014
  • The purpose of this study was to explore the factors related to internet addiction in college student of Korea. Methods: From November 19, 2012 until December 14, 2012, 300 college students from one of the universities located at K city were surveyed. This study is a cross-sectional survey of college students in K city, and data was collected through self-report questionnaires. Data was analyzed by Fisher's exact test, independent t-test to identify different according to addiction group, and logistic regression analysis in order to factors related to on health behavior, sexual behavior and mental health of among college students. According to results, factors related to risk of addiction were lower frequency of exercise (p<0.05), no eat breakfast for 2 day (p<0.05), porno magazine/porno video contact pornography (p<0.05), subjective happiness index (p<0.05), and suicidal Ideation (p<0.05). This study suggest that exercise, regular diet, important of reproductive health, subjective happiness index and Suicidal Ideation are associated with internet addiction in College student. It is necessary to develop some preventive programs for those of internet addiction.

Evaluation of the Relevance of Nutritional Status and Dietary Inflammation Index to Blood Glucose Levels in Middle-aged Women: in terms of 2013-2018's Korean National Health and Nutrition Survey Data (중년 여성의 혈당수준에 따른 영양상태 및 식이염증지수의 융합적 관련성 평가: 2013-2018 국민건강영양조사 자료 이용)

  • Park, Pil-Sook;Kityo, Anthony;Park, Mi-Yeon
    • Journal of the Korea Convergence Society
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    • v.12 no.7
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    • pp.69-82
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    • 2021
  • This study targeted 4,572 middle-aged women to examine the relationship between nutritional status and dietary inflammatory index according to blood glucose level using data from the Korean National Health and Nutrition Examination Survey (KNHANES). Data were analyzed using complex survey chi-square, General Linear Model and logisitc regression in SPSS Win 25.0 program. Women with high blood glucose (normal blood sugar→diabetes) had high rates of obesity and blood TG/HDL-cholesterol ratio. On the other hand, the Mean Adequacy Ratio (10 nutrients) and the intake of anti-inflammatory foods: beans, seeds, mushrooms, and fruits, were lower in the diabetic category. When we analysed the association between blood glucose and the Dietary Inflammatory Index, the risk of pre-diabetes and diabetes was significantly higher in the most pro-inflammatory diet category (Q5) compared to the most anti-inflammatory diet category (Q1). These findings suggest that nutritional education emphasizing the intake of various foods should be effectively conducted effectively in order to improve blood glucose among middle-aged women.

Agrometeorological Early Warning System: A Service Infrastructure for Climate-Smart Agriculture (농업기상 조기경보체계: 기후변화-기상이변 대응서비스의 출발점)

  • Yun, Jin I.
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.16 no.4
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    • pp.403-417
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    • 2014
  • Increased frequency of climate extremes is another face of climate change confronted by humans, resulting in catastrophic losses in agriculture. While climate extremes take place on many scales, impacts are experienced locally and mitigation tools are a function of local conditions. To address this, agrometeorological early warning systems must be place and location based, incorporating the climate, crop and land attributes at the appropriate scale. Existing services often lack site-specific information on adverse weather and countermeasures relevant to farming activities. Warnings on chronic long term effects of adverse weather or combined effects of two or more weather elements are seldom provided, either. This lecture discusses a field-specific early warning system implemented on a catchment scale agrometeorological service, by which volunteer farmers are provided with face-to-face disaster warnings along with relevant countermeasures. The products are based on core techniques such as scaling down of weather information to a field level and the crop specific risk assessment. Likelihood of a disaster is evaluated by the relative position of current risk on the standardized normal distribution from climatological normal year prepared for 840 catchments in South Korea. A validation study has begun with a 4-year plan for implementing an operational service in Seomjin River Basin, which accommodates over 60,000 farms and orchards. Diverse experiences obtained through this study will certainly be useful in planning and developing the nation-wide disaster early warning system for agricultural sector.

Agrometeorological Early Warning System: A Service Infrastructure for Climate-Smart Agriculture (농업기상 조기경보시스템 설계)

  • Yun, Jin I.
    • Proceedings of The Korean Society of Agricultural and Forest Meteorology Conference
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    • 2014.10a
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    • pp.25-48
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    • 2014
  • Increased frequency of climate extremes is another face of climate change confronted by humans, resulting in catastrophic losses in agriculture. While climate extremes take place on many scales, impacts are experienced locally and mitigation tools are a function of local conditions. To address this, agrometeorological early warning systems must be place and location based, incorporating the climate, crop and land attributes at the appropriate scale. Existing services often lack site-specific information on adverse weather and countermeasures relevant to farming activities. Warnings on chronic long term effects of adverse weather or combined effects of two or more weather elements are seldom provided, either. This lecture discusses a field-specific early warning system implemented on a catchment scale agrometeorological service, by which volunteer farmers are provided with face-to-face disaster warnings along with relevant countermeasures. The products are based on core techniques such as scaling down of weather information to a field level and the crop specific risk assessment. Likelihood of a disaster is evaluated by the relative position of current risk on the standardized normal distribution from climatological normal year prepared for 840 catchments in South Korea. A validation study has begun with a 4-year plan for implementing an operational service in Seomjin River Basin, which accommodates over 60,000 farms and orchards. Diverse experiences obtained through this study will certainly be useful in planning and developing the nation-wide disaster early warning system for agricultural sector.

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The $Fc{\gamma}$ receptor III genotype as a risk factor for aggressive periodontitis in Korean patients (한국인 급진성 치주염 환자의 위험요소로서 $Fc{\gamma}$ III 수용기의 유전형)

  • Kim, Myung-Hyun;Shin, Seung-Yun;Kim, Tae-Il;Seol, Yang-Jo;Lee, Yong-Moo;Rhyu, In-Chul;Chung, Chong-Pyoung;Han, Soo-Boo;Ku, Young
    • Journal of Periodontal and Implant Science
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    • v.36 no.1
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    • pp.113-123
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    • 2006
  • 연구배경 IgG에 대한 $Fc{\gamma}$ 수용기는 치주병인균에 대한 숙주 반응에 있어서 중요한 역할을 하는데, 이 중 $Fc{\gamma}RIIIa$는 NK 세포, 대식세포, 단핵구, ${\gamma}{\delta}T$세포에서 발현되며, EC2 도메인에서 158 아미노산 부위의 valine (V)-phenylalanine (F)의 유전자다형성을 보인다. $Fc{\gamma}RIIIb$는 특이적으로 중성구에 발현되는데, extracellular (ECl) Ig-like 도메인 내 4개의 아미노산 치환(substitutions)에 의한 NA1-NA2 유전자다형성을 보인다. 이 연구의 목적은 한국인에서 급진성 치주염 환자와 $Fc{\gamma}III$ 수용기의 유전자다형성과의 관련성을 알아보는 것이다. 연구방법 및 재료 치주적으로 건강한 90명 (대조군, 남자 64명, 여자 26명)과 서울대학교 치과병원 지주과에 내원하여 급진성 치주염으로 진단된 환자 43명 (aggressive periodontitis patients: AgP, 남자 30명, 여자 13명)을 대상으로 하였다. 모든 실험 대상자는 임상 실험에 대해 동의 하였고, 초진 시 전자 탐침(Florida Probe(R) Co. Gainesville, FL)을 이용하여 탐침 시 치주낭 깊이 (PPD), 임상부착수준 (CAL), 치태지수(PI), 탐침 후 출혈지수 (BOP)를 측정하였다. 또한 이들의 정맥혈에서 추출한 DNA를 PCR법, 전기영동법 등을 이용하여 $Fc{\gamma}RIIIa$, $Fc{\gamma}RIIIb$의 대립 유전자의 존재여부를 확인하였다. 이를 바탕으로 $Fc{\gamma}RIII$ 복합 유전형을 확인하여 각 군 간을 비교하였다. 연구 결과 1. $Fc{\gamma}RIIIa$에 대한 유전자다형성 연구 결과 대조군과 급진성 치주염 환자 군(AgP)사이에서는 대립 유전자 분포가 서로 유의성 있는 차이를 나타내었고 (P<0.05), $Fc{\gamma}RIIIb$에서는 유의성 있는 차이를 발견할 수 없었다. (P>0.05) 2. $Fc{\gamma}RIIIa$ 158F 대립형질이 급진성 치주염 환자에서 유의성 있게 많이 발견되어졌다. (P<0.05) 결론 이 연구를 통하여 $Fc{\gamma}RIIIa$ 유전자의 분석이 한국인의 급진성 치주염에 대한 감수성의 위험요소의 표지자로 활용할 수 있을 것으로 사료되며, 향 후 더 많은 환자를 대상으로 히는 추가 연구가 필요하다고 생각된다.

Effects of Angelica keiskei Koidzumi and Turmeric Extract Supplementation on Serum Lipid Parameters in Hypercholesterolemic Diet or P-407-Induced Hyperlipidemic Rats (명일엽과 울금 추출물의 투여가 고콜레스테롤식이와 P-407로 유도한 고지혈증쥐의 혈중 지질 함량에 미치는 영향)

  • Kim, Tae-Hyun;Son, Yeon-Kyung;Hwang, Keum-Hee;Kim, Mi-Hyun
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.37 no.6
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    • pp.708-713
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    • 2008
  • The effects of administration alone or mixed of Angelica keiskei and turmeric extract on blood lipids were evaluated in hypercholesterolemic diet or P-407-induced hyperlipidemic rats. In the study 1, female Sprague-Dawley rats weighing 160-180 g were divided into each groups and fed high cholesterol diets for 8 weeks. Experimental groups were administered with following diets: basal diet (Normal), high cholesterol diets (1% cholesterol). We did the oral administration for evaluation in experimental groups: C (vehicle), A (angelica extract), T (turmeric extract), AT (angelica extract, turmeric extract/ 1:1 complex). The concentrations of serum total cholesterol, and LDL-cholesterol were decreased by 6.8%, 9.8% in A group, by 22.1%, 28.8% in C group and by 28.2%, 35.6% in AT group, compared to the C group, respectively. HDL-cholesterol levels were not different among the experimental groups. In the study 2, we induced the hypertriglyceridemia in rats by intraperitoneal injection of P-407 (0.5 g/kg) once per three days. From the next day after P-407 injection beginning, we did the oral administration as the study 1. Angelica keiskei extract, turmeric extract and complex extract decreased serum triglyceride by 17.2%, 19.7% and 48.3%, respectively. These results suggested that Angelica keiskei and turmeric extract complex might have synergistic effect in lowering total cholesterol, LDL-cholesterol and triglyceride in hyperlipidemic rats.

The Interaction of High Sensitivity C-Reactive Protein and Uric Acid on Obesity in Koreans: Based on the Seventh Korea National Health and Nutrition Examination Survey (KNHANES VII, 2016~2018) (대한민국에서 비만에 대한 고감도 C-반응성 단백과 요산의 상호작용: 제7기 국민건강영양조사를 이용해서(KNHANES VII, 2016~2018))

  • Pyo, Sang Shin
    • Korean Journal of Clinical Laboratory Science
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    • v.53 no.4
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    • pp.342-352
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    • 2021
  • We used data from the 7th Korea National Health and Nutrition Examination Survey (KNHANES) (2016~2018) to investigate an association between high sensitivity C-reactive protein (hsCRP) and uric acid in the obese. Obesity was defined as a body mass index (BMI) of 25 kg/m2 or more, severe obesity as a BMI of 30 kg/m2 or more, and morbid obesity as a BMI of 35 kg/m2 or more. In the complex samples multiple logistic regression, despite adjustment by adding major risk factors, the odds ratio (OR) for obesity was higher in the group with high levels of both, hsCRP and uric acid than the reference group at all stages (obesity, OR 1.89, P<0.001 vs. severe obesity, OR 5.04, P<0.001 vs. morbid obesity, OR 8.20, P<0.001). The association between hsCRP and uric acid in obese patients increased from 1.89 to 8.20 as the obesity level increased, suggesting that participants with increased BMI were significantly affected by hsCRP and uric acid. Moreover, the interaction between hsCRP and uric acid was statistically significant even in the model corrected for major confounding factors (P for interaction=0.009).

Projection of Temporal and Spatial Precipitation Characteristic Change in Urban Area according to Extreme Indices (극한기후 지수에 따른 도시지역의 시공간적 강우 특성 변화 전망)

  • Soo Jin Moon;In Hee Yeo;Ji Hoon Choi
    • Proceedings of the Korea Water Resources Association Conference
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    • 2023.05a
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    • pp.316-316
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    • 2023
  • 2022년 8월 수도권 이상폭우로 인해 서울 도심지역의 지하시설, 도로, 주택 등에 침수가 발생하면서 인명 및 재산피해가 발생하였으며, 특히 동서로 가로지르는 정체전선으로 좁고 긴 비구름이 집중되면서 국지적으로 피해가 집중되었다. 서울시의 경우 도시화에 따른 불투수지역 증가 및 내수배제 불량에 따른 빗물 역류로 인한 피해가 지속적으로 발생하고 있으며, 최근에는 기후변화에 따른 방재성능목표 강우량을 초과하는 빈도의 이상폭우로 인해 하천범람과 내수배제 불량에 따른 복합적인 원인으로 침수피해 가중되고 있는 실정이다. 또한 서울시의 경우 전체 자연적, 사회적, 경제적, 환경적 요인 등의 지역적 편차가 매우 큰 도시로 지형적인 특성뿐만 아니라 취약시설(병원, 학교 등), 수방시설물(하천, 배수시설, 빗물펌프장 등) 및 방재시설(대피소, 구호소 등) 밀도 등에 따른 침수 취약성 및 위험성 등의 편차가 매우 크기 때문에 지역특성에 대한 피해사례가 다원화 되고 있는 실정이다. 본 연구에서는 30년 이상의 종관기상관측(ASOS)과 서울시 자치구별 20년 이상의 방재기상관측(AWS)자료를 기반으로 CMIP6 SSP(Shared Socioeconomic Pathways, 공통사회 경제경로)시나리오에 따른 극한기후 지수(강수강도, 호우일수, 지속기간, 1일 최대강수량, 95퍼센타일 강수일수 등)에 대한 재현성을 평가하고 공간자기상관분석 등 시공간적인 강우특성에 대한 변화를 전망하였다. 특히 여름철 강우의 경우 자치구별 편차가 크게 나타났고 이를 통해 대도시의 도심지역의 경우 세분화하여 지역의 정확한 강우특성을 파악하는 것이 필요하다는 것을 확인할 수 있었다. 본 연구의 결과는 도심지의 방재성능 초과강우 정의와 기준을 수립하고, 장기적인 수자원 및 도시계획 차원의 대책을 마련하는데 활용될 수 있을 것으로 판단된다. 기후위기에 따른 기록적인 호우(지역별 방재성능을 초과하는 강우)에 따른 재해는 구조적인 대책을 통해 모두 저감할 수 없는 한계가 있다. 하지만 인명피해를 최소화하는 것을 목표로 기후위기에 대한 적응단계로 인식하고 수리·수문학적, 사회경제학적 등 지역특성에 따른 방재성능목표 강우량에 대한 재검토와 더불어 법제도(풍수해보험, 저류조설치 의무화 등), 개인별 재해예방, 취약계층 안전망 확보, 반지하주택 침수안전대책, 재해지도 개선 등 구조적/비구조적인 대책을 통합 수립 및 보완하는 것이 필요한 시점이다.

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Childhood Obesity and Cardiovascular Health: Using 2010-2012 Data of the Korea National Health and Nutrition Examination Survey (아동기 인구 집단의 비만과 심혈관건강: 제5기 국민건강영양조사 자료 이용)

  • Lee, Go Eun;Choo, Jina
    • Korean journal of health promotion
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    • v.17 no.2
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    • pp.109-118
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    • 2017
  • Background: Abdominal obesity as measured by waist-to-height ratio (WHtR) may have stronger and inverse associations with cardiovascular (CV) health than overall obesity as measured by body mass index (BMI). However, there was some challenges for controversies. We aimed to examine the associations of WHtR and BMI with CV health among Korean children using data of the 2010-2012 Korea National Health and Nutrition Examination Survey. Methods: A cross-sectional study was conducted with the sample of 2,363 children by analyzing by gender and two-age groups (10-12 and 13-18 years). Overall obesity was categorized into 3 groups by BMI percentile: non-overweight (<85), overweight (${\geq}85$), and obesity groups (${\geq}95$). Abdominal obesity was categorized into 2 groups by WHtR: normal (<0.5) and abdominal obesity groups (${\geq}0.5$). The CV health score was defined as a z-score by calculating the sum of 7 CV factors. Results: The overweight/obesity groups had significantly lower CV health scores than the normal group (P<0.05) in boys and girls aged either 10-12 years or 13-18 years after adjusting for covariates. The abdominal obesity group also showed significantly lower CV health scores than the normal group (P<0.05) in all the groups; this significant association remained significant in boys aged 13-18 years even after further adjusting for BMI category (P<0.01). Conclusions: Among boys aged 13-18 years, abdominal obesity as measured by WHtR was significantly and inversely associated with CV health, independent of BMI category. Therefore, it should be considered to assess the level of abdominal obesity as a measure of CV health in late adolescent boys.