• Journal of dental hygiene science
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• v.14 no.4
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• pp.525-536
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• 2014

Although tobacco use has been known as one of the biggest risk factors on periodontal health, little is known about the effect of smoking cessation on it. The aim of this study was to investigate the change of concentration of matrix metalloproteinase (MMP)-8, MMP-9 and interleukin (IL)-$1{\beta}$ in gingival crevicular fluid (GCF) of 11 quit-smokers for 1 year after smoking cessation. Eleven male subjects to maintain quit-smoking for 1 year participated the oral examination, GCF and saliva collection without periodontal treatments at baseline, after 2 weeks, 2 months, 4 months, 6 months and 1 year. To confirm quit-smoking, nicotine and cotinine concentrations in saliva were measured by high performance liquid chromatography. MMP-8, MMP-9 and IL-$1{\beta}$ concentrations in GCF of upper anterior teeth area were measured by enzyme-linked immunosorbent assay. Change of MMP-8 in GCF during smoking cessation showed fluctuation with decrease (5 subjects) or increase (2 subjects) or maintenance tendency (4 subjects). Changes of MMP-9 were decrease (6 subjects), or increase (2 subjects), or maintenance (3 subjects). Change of IL-$1{\beta}$ also showed fluctuation with decrease (5 subjects) or increase (3 subjects) or maintenance tendency (3 subjects). The subjects with increase tendency had the relatively smaller amount concentration of MMP-8 and MMP-9 at the baseline. It was unclear smoking cessation without periodontal treatment could affect MMP-8, MMP-9, and IL-$1{\beta}$ in GCF. Fluctuation of periodontal biomarkers during smoking cessation might result from feedback interaction between environmental factors and periodontal cells.

• Korean Journal of Health Education and Promotion
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• v.25 no.3
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• pp.125-138
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• 2008

Purpose: This study was attempted to find out female smoking behavior and the smoking related factors. Method: Study subjects were 226 female smokers who have visited temporary clinic or smoking cessation clinic run by 10 public health centers in Incheon. The data were collected through the questionnaire specially designed for this study from April 1 to June 30, 2008. The data were analyzed by the SPSS 12.0 program. Result: 68.0% of feale smokers have smoked habitually. The average daily smoking amount of the subjects was $12.0{\pm}8.7$ ea, average rate of nicotine dependence was $4.2{\pm}2.2$ points, the mean smoking duration was $12.7{\pm}9.3$ years, and the smoking start age was $23.1{\pm}8.5$ year old. The smoking behavior by the drinking frequency showed significant difference in average daily smoking amount and rate of nicotine dependence(p<.05). Also the smoking behavior by exercise showed significant difference in current smoking frequency(p<.05). There was positive relation between female smoking behavior and monthly income, frequency of drinking, exercise, and stress respectively(p<.05, p<.01). Conclusion: Compared to a male smoker, the average daily smoking amount of a female smoker was less and the duration of smoking was longer. This study suggests that not only a social movement about a female smoking cessation is imperative but also smoking cessation programs should be combined with reduced drinking consumption, exercise and stress relief programs. Moreover, early intervention for preventing teenager smoking should be added to smoking cessation programs.