• Title/Summary/Keyword: 변동범위

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A Study on the Establishment of Acceptable Range for Internal Quality Control of Radioimmunoassay (핵의학 검체검사 내부정도관리 허용범위 설정에 관한 고찰)

  • Young Ji, LEE;So Young, LEE;Sun Ho, LEE
    • The Korean Journal of Nuclear Medicine Technology
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    • v.26 no.2
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    • pp.43-47
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    • 2022
  • Purpose Radioimmunoassay implement quality control by systematizing the internal quality control system for quality assurance of test results. This study aims to contribute to the quality assurance of radioimmunoassay results and to implement systematic quality control by measuring the average CV of internal quality control and external quality control by plenty of institutions for reference when setting the laboratory's own acceptable range. Materials and Methods We measured the average CV of internal quality control and the bounce rate of more than 10.0% for a total of 42 items from October 2020 to December 2021. According to the CV result, we classified and compared the upper group (5.0% or less), the middle group (5.0~10.0%) and the lower group (10.0% or more). The bounce rate of 10.0% or more was compared by classifying the item of five or more institutions into tumor markers, thyroid hormones and other hormones. The average CV was measured by the overall average and standard deviation of the external quality control results for 28 items from the first quarter to the fourth quarter of 2021. In addition, the average CV was measured by the overall average and standard deviation of the proficiency results between institutions for 13 items in the first half and the second half of 2021. The average CV of internal quality control and external quality control was compared by item so we compared and analyzed the items that implement well to quality control and the items that require attention to quality control. Results As a result of measuring the precision average of internal quality control for 42 items of six institutions, the top group (5.0% or less) are Ferritin, HGH, SHBG, and 25-OH-VitD, while the bottom group (≤10.0%) are cortisol, ATA, AMA, renin, and estradiol. When comparing more than 10.0% bounce rate of CV for tumor markers, CA-125 (6.7%), CA-19-9 (9.8%) implemented well, while SCC-Ag (24.3%), CA-15-3 (26.7%) were among the items that require attention to control. As a result of comparing the bounce rate of more than 10.0% of CV for thyroid hormones examination, free T4 (2.1%), T3 (9.3%) showed excellent performance and AMA (39.6%), ATA (51.6%) required attention to control. When comparing the bounce rate of 10.0% or more of CV for other hormones, IGF-1 (8.8%), FSH (9.1%), prolactin (9.2%) showed excellent performance, however estradiol (37.3%), testosterone (37.7%), cortisol (44.4%) required attention to control. As a result of measuring the average CV of the whole institutions participating at external quality control for 28 items, HGH and SCC-Ag were included in the top group (≤10.0%), however ATA, estradiol, TSI, and thyroglobulin included in bottom group (≥30.0%). Conclusion As a result of evaluating 42 items of six institutions, the average CV was 3.7~12.2% showing a 3.3 times difference between the upper group and the lower group. Cortisol, ATA, AMA, Renin and estradiol tests with high CV will require continuous improvement activities to improve precision. In addition, we measured and compared the overall average CV of the internal quality control, the external quality control and the proficiency between institutions participating of six institutions for 41 items excluding HBs-Ab. As a result, ATA, AMA, Renin and estradiol belong to the same subgroup so we require attention to control and consider setting a higher acceptable range. It is recommended to set and control the acceptable range standard of internal quality control CV in consideration of many things in the laboratory due to the different reagents and instruments, and the results vary depending on the test's proficiency and quality control materials. It is thought that the accuracy and reliability of radioimmunoassay results can be improved if systematic quality control is implemented based on the set acceptable range.

High Resolution and Large Scale Flood Modeling using 2D Finite Volume Model (2차원 유한체적모형을 적용한 고해상도 대규모 유역 홍수모델링)

  • Kim, Byunghyun;Kim, Hyun Il;Han, Kun Yeun
    • Proceedings of the Korea Water Resources Association Conference
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    • 2020.06a
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    • pp.413-413
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    • 2020
  • Godunov형 모형을 이용한 홍수모델링에서는 일반적으로 구조적 사각격자나 비구조적 삼각격자가 주로 적용된다. 2차원 수치모형을 이용한 홍수모델링에서 연구유역의 정보가 격자의 노드나 중심에 입력되므로 적용격자의 유형과 생성방법에 따라 모형의 입력자료 오차에 영항을 줄 수 있다. 따라서, 연구유역이 지형 변동성이 심한 지역이거나 흐름형상이나 흐름변동이 심한 구간이라면, 고해상도 격자를 통해 모형의 입력자료 오차를 최소화할 할 수 있다. 본 연구에서는 2가지 유형에 대한 연구를 수행하였다, 첫 번째는 홍수해석을 위한 2차원 모형의 격자형상과 해상도에 따른 홍수위 및 홍수범람범위를 비교·분석하는 연구를 수행하였다. 연구유역은 2000년 10월 29일부터 11월 19일까지 홍수가 발생한 영국의 Severn 강 유역이다. 연구유역의 홍수 모델링을 위한 지형자료는 3m 해상도의 LiDAR(Light Detection And Ranging)를 이용하여 구축하였으며, 격자유형 및 해상도에 따른 2차원 홍수위 및 홍수범람범위를 비교·분석하기 위해서 홍수 발생기간 동안 촬영된 4개(2000년 8월 11, 14, 15, 17일)의 ASAR(Advanced Synthetic Aperture Radar) 영상자료를 활용하였다. 즉, ASAR 영상으로 촬용된 최대범람시기 및 홍수류의 배수기를 활용하여 최대범람범위뿐만 아니라 홍수가 증가하는 시기와 하류단 배수로 인해 홍수가 감소하는 시기를 모두 포함하는 홍수범람범위에 대한 격자유형별 2차원 홍수범람모형의 계산 결과에 대해 비교하였다. 두 번째는 아마존 강 중류유역의 2,500K㎡ 면적에 해당하는 대규모 유역에 대해 SRTM(Shuttle Radar Topography Mission) 지형자료를 이용하여 홍수기와 갈수기에 대해 2차원 모델링을 수행하고 그 결과를 위성자료와 비교하였다.

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An Analytical Model for Predicting Heat Transport due to a Point Source in Coastal Water under a Spring-Neap Modulation of Tidal Currents (조류의 대.소조 변동이 존재하는 연안역에서의 점열원에 의한 열오염의 이동 예측을 위한 해석해 모형)

  • 이호진;김종학
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.16 no.2
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    • pp.92-102
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    • 2004
  • In this paper, an analytical solution of calculating the excess temperature field due to a point heat source is presented in the presence of spring-neap modulation of convective alongshore flow. The basic form of the solution is identical to that given by Jung et al. (2003) but the convective term in the exponential kernel function is extended and a spring-neap variation in the horizontal eddy diffusivity is newly introduced. A set of calculations have been performed to examine the sensitivity of the heat build-up to the change in current fields and turbulent dispersion. Results indicate that the excess temperature field is confined within the tidal excursion distance, while the excess temperature field beyond the distance is mainly controlled by the horizontal diffusion. The heat build-up within the distance is considerably affected by the spring-neap variation in the horizontal eddy diffusivity; the relatively high excess temperature more than 1$^{\circ}C$ is extended further when the eddy diffusivity has spring-neap modulation.

Variations of Secchi Depth in Coastal Water, Masan Bay in Korea (마산만의 투명도 변동)

  • 염말구;정연수
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.39 no.1
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    • pp.44-49
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    • 2003
  • Masan Bay is one of the most heavily polluted bay in Korea owing to the large industrial complex and urban area. Water transparency, Secchi depth in meter, was observed 33 times totally at four sites during 1995 through 2002 and analysed statistically. The range was 0.2∼7.2m, mean 204m, and variation coefficient 60% in totally. Roughly speaking, monthly mean showed lower value April or July than other months. Seasonal mean showed lower in spring or summer than other seasons. Yearly mean was lowest in '95 and '98 during 7 years. Each sampling site showed a different patterns by the monthly, seasonal or yearly transparencies. Inner bay area, S1 site, showed lowest transparency and highest variation coefficient owing to the streamlets and urban area. And it was supposed that one of the important factor affecting different transparency distribution of most seaward site, S4 site, among four sites in the Masan Bay may be the underwater effluents of urban sewage water treated.

Development of Reference Epoch Adjustment Model for Correction of GPS Precise Point Positioning Results (GPS 정밀단독측위 성과의 보정을 위한 기준시점 조정모델 개발)

  • Sung, Woo-Jin;Yun, Hong-Sik;Hwang, Jin-Sang;Cho, Jae-Myoung
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.30 no.3
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    • pp.249-258
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    • 2012
  • In this study, the epoch adjustment model was developed to correct GPS precise point positioning result to be suitable for the current geodetic datum of Korea which is tied at past epoch statically. The model is based on the formula describing crustal movements, and the formula is composed of several parameters. To determine the parameters, the data gathered at 14 permanent GPS stations for 10 years, from 2000 to 2011, were processed using GIPSY-OASIS II. It was possible to determine the position of permanent GPS stations with an error range of 16mm and the position of check points with an error range of 12mm by appling the model to GPS precise point positioning result. It is considered that more precise model could be calculated by using GPS data of more permanent GPS stations.

A study on the coefficients of variation of seismic load effect for the limit state design of shield tunnel based on the reliability analysis (신뢰성 기반 쉴드 터널의 한계상태설계를 위한 지진하중 효과의 변동계수에 관한 연구)

  • Park, Young-Bin;Kim, Do;Byun, Yosep;Lee, Gyu-Phil
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.22 no.3
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    • pp.311-321
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    • 2020
  • In this study, coefficient of variation for the seismic load effect on the segment lining was calculated. The statistical characteristics of the soil property were analyzed for the probability characteristics of domestic soil. In order to calculate the coefficient of variation for the seismic load effect, the MCS technique was applied, and the closed-form equation was applied to calculate the seismic load effect. As a result of calculating the coefficient of variation, the coefficient of variation of the seismic load effect on the weathered soil was analyzed in the range of 0.06~0.15, and the coefficient of variation was judged to be used as basic data for designing the limit state of the shield tunnel on seismic condition.

자연방사선의 변동범위내 - 체르노빌사고영향에 관한 OECD/NEA 보고서 -

  • 한국원자력산업회의
    • Nuclear industry
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    • v.8 no.7 s.65
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    • pp.93-95
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    • 1988
  • 소련 체르노빌원전에서 사고가 발생한지 2년이 넘었다. 우리나라에서는 방사성물질 강하 등의 영향이 거의 없었으나, 지리적으로 가까운 유럽에서는 사고 당시 심각한 영향을 받은 국가가 있었다고 한다. 경제협력개발기구/원자력기관(OECD/NEA)이 금년 1월 사고영향에 관한 보고서를 발표하였다. 다음은 방사선에 의한 영향을 중심으로 한 동 보고서의 개요이다.

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단상 열사이폰 루프의 작동특성에 관한 연구

  • 이진호;김태열;설신수
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.14 no.4
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    • pp.960-970
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    • 1990
  • 본 연구에서는 단상 밀폐 사각형 열사이폰 루프에서 가열부는 일정 열유속으 로 가열되고 냉각부는 일정온도로 냉각될 경우에 대해 루프 경사각도, 종횡비, 작동유 체 종류 및 관 직경변화에 대한 유동 및 온도변동 특성과 이에따른 전열성능 및 안정 작동범위를 실험적으로 조사하였다.

The tidal effect of seawater/freshwater interface at the coastal aquifer of the Yongho Bay in Busan (부산 용호만 해안대수층에서 해수/담수 경계면의 조석효과)

  • Kim, Sung-Soo;Kang, Dong-Hwan;Kim, Byung-Woo;Kim, Tae-Yeong;Chung, Sang-Yong
    • Proceedings of the Korea Water Resources Association Conference
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    • 2009.05a
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    • pp.1960-1963
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    • 2009
  • 본 연구에서는 부산시 용호만 해안대수층에서 전기전도도와 지하수위의 수직적인 관측을 통해, 조석에 의한 해수/담수 경계면의 변동을 산정하였다. 연구지역은 부경대학교 대연캠퍼스 기숙사 신축부지 주변 해안대수층이며, 응회질퇴적암과 안산암 및 안산암질 화산각력암 등으로 구성되어 있다. 관측공의 개발심도는 120 m, 케이싱심도는 19 m, 내경은 0.2 m, 관측공과 해안선의 이격거리는 180 m 정도이다. 전기전도도에 의해 산정된 밀도는 담수에서 997.58 $kg/m^3$, 해수에서 1020.36 $kg/m^3$ 이었다. 관측기간(2008년 8월 21일${\sim}$10월 18일) 동안 해수/담수 경계면의 변동 범위는 해수면 기준 -21.69${\sim}$-21.53 m 이었으며, 경계면의 평균 위치는 해수면 기준 -21.62 m 정도이었다. 해수/담수 경계면과 지하수위의 상관성은 매우 높게 나타났으며, 해안대수층 내 해수/담수 경계면의 변동은 조석의 일(고조, 저조) 및 보름(대조, 소조) 단위의 변동에 영향을 받고 있음이 확인되었다. 관측기간 동안 지하수위는 전반적으로 하강하는 경향을 나타내었으며, 이는 관측기간이 풍수기에서 갈수기로 전환되고 있었기 때문이다. 향후에는 지속적인 관측을 통해, 용호만 해안의 해수면 상승에 의한 내륙으로의 해수침투를 연구하고자 한다.

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Variation of Water Temperature in Chungmu Port (충무항의 수온 변동)

  • Yeom, Mal-Gu;Kim, Sam-Gon
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.20 no.2
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    • pp.79-82
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    • 1984
  • Seasonal and secular variations of water temperature in Chungmu port were investigated with the data obtained from the Technical Reports(1976~1983) of Hydrographic Office. Monthly and annual range of water temperature were 2 to 8$^{\circ}C$ and 18 to 21$^{\circ}C$, respectively. The coefficients of variance of monthly mean water temperature were 0.015(February, 1976) to 0.208(December, 1980) and their values were smaller in the summer season than in the winter season. The result of harmonic analysis for investigating the seasonal variation of water temperature was T(t)=15.66+8.06 cos(10$^{\circ}$t-233.5)+0.92 cos(20$^{\circ}$t-216). The periods of secular variation were about 2 years and 3 years.

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