• Clinical and Experimental Pediatrics
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• v.45 no.10
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• pp.1219-1226
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• 2002

Purpose : To assess the clinical characteristics of the 2000-2001 measles outbreak in the Seoul metropolitan area, Korea, the clinical data of measles inpatients were analyzed. Methods : Three hundred and five children diagnosed with measles by clinical manifestation from July, 2000 to February, 2001, in Seoul, Ilsan and Ansan City were grouped according to their age and investigated for clinical manifestations, vaccination history and measles-specific IgM/IgG antibody positivity. Results : Thirty eight point seven percent of the subjects were less than 12 months of age, 27.5 % were 12-47 months of age and 33.8% were 48 months of age or older. There was no significant sexual difference(male : female=1.2 : 1). This epidemic started in June, 2000 and the number of patients increased abruptly in October, peaked in December and finally decreased after February, 2001. It started from the older age group and moved to the younger. Sixty five point two percent had a history of more than 1-dose vaccination and 13.6% of the patients equal or more than 48 months of age had a history of 2-dose vaccination. Primary vaccine failure rate was 59.4%(107/180) and secondary vaccine failure rate was 3.9%(7/180) in 1 dose vaccinees. Sixty one point six percent showed more than one complication and 38.4% had no complication. The most common complication was pneumonia(31.8 %), followed by bronchitis(11.5%) and acute otitis media(4.6%). Vaccination and dose were not related significantly with the occurrence of complications. Conclusion : Compared with previous outbreaks in Korea, clinical features showed no specific change in the 2000-2001 measles epidemic. However, primary vaccine failure rate was so high that the second vaccination at four to six years of age must be emphasized in Korea.

• Korean Journal of Poultry Science
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• v.32 no.2
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• pp.113-123
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• 2005

Avian influenza (AI) virus (AIV) is distributed worldwide and it has been isolated from various species of wild and domestic birds. AI transfers with high speed and shows diverse pathogenicity syndroms. In Korea, several low Pathogenic AIV, H9N2, have been isolated from the commercial farms with severe decrease of egg production and mortality resulted in severe economic loss since 1996. Therefore, it has been requested to develop AI vaccines to prevent clinical signs and economic losses from the field infection of AIV. To develop a killed vaccine that efficiently prevents low pathogenic AIV (H9N2), evaluation on the pathogenicity and selection of an inactivator for H9N2 is taking place and is being tested safety and immunogenicity of vaccine produced. Based on the pathogenicity test and viral reisolation test, the ADL0401 isolate is the characteristic low pathogenic AIVs and has fairly similar biologic functions compared with MS96 which is the official low pathogenic AIV (H9N2) and one of the predominant AIV isolated from poultry farms in Korea. In antigenicity tests, the ADL0401 and MS96 virus have no significant antigenic difference. In inactivation tests, the ADL0401 isolates can be easily inactivated with $0.1\%$ Formalin at $37^{\circ}C$ within 1 hour with a little decrease of HA titer. The vaccine developed in the present report has no harmful effect on bird and forms good immune capability. Therefore, the isolates, ADL0401 can be used for a killed vaccine which can reduce the clinical signs and viral shedding in the birds infected with H9N2 low pathogenic AIVs.

• Proceedings of the Korean Society of Veterinary Service Conference
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• 2001.06a
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• pp.181.2-182
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• 2001

• The Korea Swine Journal
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• v.13 no.5 s.141
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• pp.40-41
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• 1991

"쌀시장도 일부 개방이 불가피하다'는 상공장관이나 제네바 대사의 발언은 개발때 국민의 충격을 최소화 하기 위한 예방 접종이라는 평들이 많다. 이것이 사실이라면 당정협의회에서 즉시 제네바대사를 소환해서 면직시키라는 결정도 백신후유증이 너무 커 후유증을 치료하기 위한 치료제로 보면 될 것 이다

• The Korea Swine Journal
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• v.10 no.6 s.106
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• pp.95-99
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• 1988

소독은 오염된 균수를 줄이는 것으로 집단방역의 제1방역선은 소독이요, 제2방역선은 백신접종이고, 제3방역선은 치료인 것이다. 양돈장의 효과적인 소독은 화창한 날 실시, 발판소독조관리철저, 돈방 소독은 주기적으로 실시, 돈체분무 소독, 음수소독 등이 중요하다

• KOREAN POULTRY JOURNAL
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• v.25 no.8 s.286
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• pp.131-135
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• 1993

닭에서의 호흡기질병은 겨울철 밀폐상태에서만 많이 발생하는 것으로 믿고있는 사양가들이 많다. 그러나 요즘같이 더운 계절에도 호흡기질병은 발생하고 있으며 지금 이 시간에도 약을 투여하고 있는 농장이 있을 걸로 보인다. 호흡기질병의 원인은 무엇이며 어떻게 대처하여야 하는가에 대해 알아보자.

• 월간낙농육우
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• v.23 no.9 s.257
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• pp.98-101
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• 2003

최근 국내 부루세라병 발생두수가 예년에 비해 증가하고 있으며 가축의 이동 증가와 사육규모의 증가는 발생위험을 높일 뿐만 아니라 발생규모의 증가를 가져와 일단 발병시 피해가 훨씬 심각하다. 또한 근래에 부루세라 백신접종에 대한 논의가 다시 되고 있어 이번 기회에 부루세라병에 대한 궁금증을 알아 보고자 한다.

• Proceedings of the Korean Society of Veterinary Service Conference
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• 2000.06a
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• pp.176-176
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• 2000

• KOREAN POULTRY JOURNAL
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• v.24 no.4 s.270
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• pp.46-49
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• 1992

육계산업이 수입개방과 인력난, 환경문제 등 여러 어려운 여건속에서 살아남기 위해 사육규모의 확대, 전업화, 정밀화가 요구되며 이를 위해서는 시설자동화를 하여 생산성 향상에 주력하여 생산비인하에 초점을 맞추어 나가야 한다.

• 건강소식
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• v.11 no.2 s.99
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• pp.16-18
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• 1987

우리나라에서는 특히 간염의 발생율이 특히 높은 나라이며 신생아 시기에 걸린 간염은 성인이 된 후 간경화증으로 발전 된다고 하며, 나아가 간암으로 진행 될 가능성이 높으므로 출생 즉시 간염 백신을 접종하여 이후항체 형성 여부를 검사하여 면역기능이 생겼는지를 아는 것이 중요하다.