• Title/Summary/Keyword: 방호관

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Drug Toxicities of S-2-(W-aminoalkylamino) ethyl and S-2, W-diaminoalkyl Isothiuronium Bromides and their Potent Radioprotective Effects (S-2, - (W-aminoalkylamino) ethyl 및 S-2, W-diaminoalkyl Isothiuronium Bromide 의 약독성(藥毒性)과 방사선장해방호(放射線障害防護) 효과)

  • Kim, You-Sun;Kim, Suc-Won
    • Journal of Radiation Protection and Research
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    • v.10 no.2
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    • pp.122-129
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    • 1985
  • S-2, W-diaminopentyl isothiuronium bromide and relevant thiophosphate derivative were prepared starting from both phthalimide and l-ornithinic acid. Drug toxicities of the prepared isothiuronium bromide and S-2-(W-aminoalkylamino) ethyl isothiuronium bromides were tested through ICR male mice, 4 and 8 weeks old and weighing $25{\sim}35g$. The former compound was found to be less toxic than those of latter compounds. This difference of drug toxicities seemed to be originated from their chemical structures, which were examined through IR Spectrometry Radioprotective effects of these compounds were discussed through relevant research data and diaminopentyl derivatives are considered to be a potent radioprotectant with low drug toxicity.

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A Study on the Plastic deformation Absorption Characteristics of Aluminum-Polyethylene Composite Structure Sprinkler Pipe (알루미늄 합성수지 복합 구조 스프링클러 파이프의 변위 흡수 특성 연구)

  • Kim, Jun-Gon;Kim, Kwang-Beom;Noh, Sung-Yeo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.1
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    • pp.426-433
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    • 2019
  • After an earthquake, fire and gas explosions are more likely to cause more casualties in cities with many apartment buildings and large complex buildings. In order to prevent this, seismic design is necessary for the fire protection sprinkler system. However, most systems currently use stainless-steel pipes, although synthetic resin pipes are used in some special places. These materials are susceptible to vibration and earthquakes. This study evaluated the displacement absorption flexibility of polyethylene (PE) and aluminum (Al) multi-layered composite pipes to increase the seismic performance in a vibration environment and during earthquakes. The seismic performance was compared with that of a stainless-steel and PE pipes. The seismic characteristics can be measured by measuring the amount and extent of vibration transmitted by the sprinkler pipe. This method can be used to judge the seismic characteristics to attenuate the vibration during an earthquake. The seismic characteristics of the pipe were verified by comparing the logarithmic attenuation rate to the initial response displacement of the vibration generated by the transverse vibration measurement method.

Protective Effects of New Herbal Composition (MH-30) against Radiation Injuries in Hematopoietic and Self-Renewal Tissues (생약조성물(MH-30)의 면역조혈계 및 재생조직 방사선 손상에 대한 방호 효과)

  • Jung, Uhee;Park, Hae-Ran;Lee, Ho-Yong;Baek, Ga-Young;Jo, Sung-Kee
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.45 no.7
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    • pp.948-957
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    • 2016
  • We previously developed an herbal composition (HemoHIM) based on the water extracts of Angelica gigas radix, Cnidium officinale rhizoma, and Paeonia japonica radix to protect and recover hematopoietic and intestinal tissues against radiation injuries. In this study, to develop a composition with improved activities based on enhanced fat-soluble polyphenol contents, we prepared a new herbal composition, MH-30, from the above three herbs by 30% ethanol extraction and hot water extraction. HPLC analysis of the ethanol fractions of MH-30 and HemoHIM revealed that MH-30 had higher contents of many fat-soluble polyphenol compounds than HemoHIM (8.7-fold increase for decursin), whereas contents of water-soluble polyphenol compounds showed little differences between the two compositions. Then, we evaluated MH-30 and HemoHIM for their in vitro antioxidant and immune cell-stimulating activities as well as in vivo protective effects against radiation injuries in hematopoietic and self-renewal tissues. In antioxidant activity assays, MH-30 showed higher hydroxyl radical scavenging activity than HemoHIM (1.4- to 1.9-fold for compositions and 2.3- to 4.5-fold for ethanol fractions). On the other hand, MH-30 and HemoHIM exhibited similar immune cell-stimulating activities as measured by in vitro lymphocyte proliferation. MH-30 increased endogenous spleen colony formation, decreased bone marrow cell apoptosis, and enhanced survival of intestinal crypts in irradiated mice, demonstrating effective protection of MH-30 against radiation-induced injuries in hematopoietic and self-renewal tissues. The 30-day survival rate of lethally irradiated mice, a comprehensive index for radioprotective efficacy, was also elevated by MH-30. Noticeably, MH-30 showed higher protective effects than HemoHIM in all mouse experiments. These results demonstrate that MH-30 can protect hematopoietic and self-renewal tissues against radiation injuries more effectively than HemoHIM. Therefore, MH-30 can be a good candidate to reduce radiation injuries in hematopoietic and self-renewal tissues incurred by radiation accidents or cancer radiation therapy.

Airport security supervisor's individual attitude effets on the screening equipment factors (공항보안감독관의 개인태도가 검색장비 운영요인에 미치는 영향)

  • Jung, Joo-Sub
    • Korean Security Journal
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    • no.29
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    • pp.279-300
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    • 2011
  • Countries recognize seriousness and concern about aviation terrorism, try to stamp out of it but aviation terrorism has been increasing in the world. Airport security is completely up to the result of security screening for passengers, check-in baggages and cargo at the check point. To complete effectively human and physical screening at the airport, it is essential to secure modernized screening equipment and specialized security screener, and airport security supervisor to supervising them. In this study, A survey conducted to find out the effect on screening equipment operating factors of airport security supervisor's individual attitude. The results of the study are as follow First, the duty view of airport security supervisor meaningfully affect expertise of screening equipment operating factors, satisfaction, reliability, and education and training, national point of view meaningfullly doesn't affect screening equipment operating factors. Second, the working condition effects on the education and training, if the working condition is getting better, intent to change occupation is getting lower. Third, duty stress meaningfully effects on the intent to change occupation, now airport security supervisor works in poor condition. Therefore, airport security supervisor needs to be prude of protecting the airport from the terrorism and various attacks and various kinds of aviation security regulations and procedures and comply with operating standards and keep the life of the country and its people, and needs to change awareness. And It is nessasary for government or airport authority or airline to prepare countermeasure for the improvement of their labor conditions.

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Comparison Analysis on the Structural Stability of Concrete Median Barriers Using Commercial Software (상용 프로그림을 이용한 콘크리트 중앙분리대 방호울타리들의 구조적 안정성에 대한 비교 분석)

  • 주재웅;이성관
    • Proceedings of the Computational Structural Engineering Institute Conference
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    • 2002.10a
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    • pp.177-184
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    • 2002
  • The concrete median barriers are the most popular safety appurtenances that can be installed on narrow medians and are effective in keeping uncontrolled vehicles from crossing into opposing lanes of traffic. It is necessary to install and maintain median barriers because it is very difficult to reserve enough room required for medians in KOREA. And concrete median barriers are accepted as the actual alternatives for median barriers, mostly because they require almost no maintenance even after serious collisions. Typical concrete median barriers are 810mm high and have 596mm high glare screens on top of them. But we have experienced a number of “climb” and “roll-over” accidents of heavy vehicles until now, and most of all, there have been some serious accidents caused by the part of broken glare screens. We have performed many computer simulations for the evaluation of the crashworthiness of concrete median barriers, and through the simulations we have tried to find a proper type of concrete median barrier.

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Estimation of Damage in Electric Power Networks due to High Power Electromagnetic Pulse (고출력 전자기파에 대한 전력망 피해 비용 산출)

  • Hyun, Se-Young;Du, Jin-Kyoung;Kim, Wooju;Yook, Jong-Gwan
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.25 no.7
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    • pp.757-766
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    • 2014
  • In this paper, economic loss due to high power electromagnetic pulse is estimated and the methodology used for calculating its impacts is suggested using a macro approach. In order to investigate the most critical infrastructure for the high power electromagnetic pulse assault, the vulnerability assessment that provides information on the threats of concern is conducted. As a result, this study concentrates on the electric power networks. The presented assessment model is considered with gross domestic product (GDP) and energy consumption when the electric power networks are damaged due to high power electromagnetic pulse. In addition, economic losses are calculated by the extent of damages considering different types of the high power electromagnetic pulse assault generated by nuclear and man-made weapon. Through the estimation of these damages, the resulted economic loss will be compared with the protection cost. Consequently, protection of the vulnerable infrastructures can be prepared against electromagnetic pulse attack.

Vulnerability Mitigation System Construction Method Based on ATT&CK in M ilitary Internal Network Environment (국방 네트워크 환경에서 ATT&CK 기반 취약점 완화 체계 구축 방안)

  • Ahn, Gwang Hyun;Lee, Hanhee;Park, Won Hyung;Kang, Ji Won
    • Convergence Security Journal
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    • v.20 no.4
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    • pp.135-141
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    • 2020
  • The Ministry of National Defense is strengthening the power and capacity of cyber operations as cyber protection training is conducted. However, considering the level of enemy cyber attack capability, the level of cyber defense capability of the ministry of national defense is significantly low and the protection measures and response system for responding to cyber threats to military networks are not clearly designed, falling short of the level of cyber security capabilities of the public and private sectors. Therefore, this paper is to investigate and verify the establishment of a military internal network vulnerability mitigation system that applies the intention of attackers, tactics, techniques and procedures information (ATT&CK Framework), identified military internal network main threat information, and military information system security requirements with military specificity as factors that can establish a defense network vulnerability mitigation system by referring to the domestic and foreign cyber security framework It has the advantage of having.

Protective Effect of a Herbal Preparation (HemoHIM) on the Self-Renewal Tissues and Immune System against γ-Irradiation (방사선에 대한 생약복합조성물(HemoHIM)의 재생조직 및 면역계 방호 · 회복촉진 효과)

  • Jo, Sung-Kee;Park, Hae-Ran;Jung, Uhee;Oh, Heon;Kim, Sung-Ho;Yee, Sung-Tae
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.34 no.6
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    • pp.805-813
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    • 2005
  • In our previous study, a novel herb mixture (HIM-I) of Angelim gigas radix, Cnidium officinale rhizoma, and Paeonia japonica radix was developed to protect the intestinal and immune systems and promote its recovery against radiation damage. In this study, a new herbal preparation (HemoHIM) with the high immune modulating activity was developed from HIM-I. HIM-I was fractionated into ethanol fraction (HIM-I-E) and polysaccharide fraction (HIM-I-P). And HemoHIM was prepared by adding HIM-I-P to HIM-I. The protective activities against $\gamma$ -irradiation were compared among HemoHIM, HIM-I and the fractions. HemoHIM and HIM-I significantly decreased the radiation-induced DNA damage in vitro, and scavenged hydroxyl radicals in a dose-dependent manner. HemoHIM showed similar activity to HIM-I. In vitro proliferation assay with mouse lymphocytes and bone marrow cells showed that HIM-I-P was remarkably higher than HIM-I and HIM-I-E in cell proliferating activity. HemoHIM showed higher activity than HIM-I and this might be associated with the higher polysaccharide content. The in vivo protective effects of HemoHIM and HIM-I were investigated in $\gamma$-irradiated mice. HemoHIM increased the surviving intestinal crypts to a similar extent compared with HIM-I. In contrast, HemoHIM appeared to be more effective than HIM-I in endogenous spleen colony formation assay. The recovery of white blood cells and lymphocytes in irradiated mice were significantly enhanced by the administration of HemoHIM. Also HemoHIM administration prolonged the survival of irradiated mice. These results showed that the novel herbal preparation, HemoHIM, effectively protected the self-renewal tissues and immune system, and promoted the survival of irradiated mice. Moreover, in comparison with HIM-I, HemoHIM maintained similar activity in the reduction of oxidative damage of self-renewal tissue but exhibited the higher activity in protection and proliferation of immune and hematopoietic cells. These results suggested that HemoHIM might be more effective than HIM-I in immune modulation as well as radioprotection.

Power-Line EMI Filter for Broad-Band (전원용 광대역, 고성능 EMI 필터 개발에 관한 연구)

  • Chung Yeong-Chul;Lee Kyung-Won;Yook Jong-Gwan;Park Han-Kyu
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.16 no.1 s.92
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    • pp.56-65
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    • 2005
  • We proposed the Power-line EMI filter for vehicle-shelter which have attenuation performance of 100 dB from 10kHz to 1 GHz. The inductor and capacitor for EMI filter design was charactenzed using circuit simulator and then, we experimentally verified 100 dB attenuation for the conducted emission noise through power line. This results will be used for the application systems of protection weapons against EMI attacks as well as vehicle-shelter.

Strength Characteristics of Passive Fire Protection Material Applied Structural Members on Fire Load (수동화재보호 재료가 적용된 구조부재의 화재하중에 대한 강도 특성)

  • Jo, Sang Chan;Yu, Seung Su;Seo, Jung Kwan
    • Journal of the Society of Naval Architects of Korea
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    • v.59 no.1
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    • pp.29-38
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    • 2022
  • In offshore installations, fires cause the structure to lose its rigidity and it leads to structural integrity and stability problems. The Passive Fire Protection (PFP) system slows the transfer rate of fire heat and helps prevent the collapse of structures and fatality. Especially, intumescent epoxy coating is widely used in the offshore industry, and not only is the material cost expensive, but it also takes a lot of time and cost for construction. Several studies have been conducted on the efficient application and optimal design of the PFP system. However, the mechanical properties and the strength of the PFP material have not been considered. In addition, researches on the correlation between the thickness of PFP and the structural behavior were insufficient. Therefore, this study aims to analyze the thermal and mechanical effects of the PFP on the structure when it is applied to the structural member. In particular, it is intended to resolve the change in strength characteristics of the structural members as the thickness of the PFP increases.