• Title/Summary/Keyword: 방출속도

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Chemical and toxicological properties of controlled release granular formulations of acetamiprid using wax matrix (왁스매트릭스를 이용한 방출조절헝 acetamiprid 입제의 화학적, 독성학적 특성)

  • Lee, Weon-Kee;Yang, Kyung-Hyung;Lee, Chang-Hyuk;Lee, Seung-Il;Hwang, In-Cheon
    • The Korean Journal of Pesticide Science
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    • v.9 no.3
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    • pp.243-249
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    • 2005
  • The chemical and toxicological studies were conducted with acetamiprid 2% granules including different controlling agents for development of controlled-release acetamiprid 2% granule. The fundamental formulation recipe of acetamiprid 2% granule was prepared by the insoluble matrix using polyethylene wax. Starch, cellulose and mineral (calcium carbonate) were used as controlling agents. As a result of studies, release rate of active ingredient from granules into water static condition at $25^{\circ}C$ was increased by addition of starch and cellulose, but was decreased by addition of calcium carbonate. We could select calcium carbonate as controlling agent and make three granules which there were difference in release profiles of active ingredient according to contents of polyethylene wax. 24 hours-release rates of acetamiprid from three granules into water static condition at $25^{\circ}C$ were respectively 75, 50 and 25% when contents of wax were 2, 10 and 20%. The granule which 24 hours-release rate was 25% showed lower acute toxicity against mice and rats.

AE Source Location in Anisotropic Plates by Using Nonlinear Analysis (비선형방정식을 이용한 이방성판의 음향방출 위치표정)

  • Lee, Kyung-Joo;Kwon, Oh-Yang
    • Journal of the Korean Society for Nondestructive Testing
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    • v.21 no.3
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    • pp.281-287
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    • 2001
  • For the conventional two-dimensional source location of acoustic emission (AE) based on the threshold crossing, wave velocity has to be measured in the actual structure to calculate the arrival-time difference and thus to form the two hyperbolae. Velocity is dependent on the fiber orientation, however, due to the dependence of elastic modulus on fiber orientation in anisotropic materials such as compost#e plates. This tan affect the accuracy of AE source location and make the source location procedure complicated. In this study, we propose a method to reduce the location error in anisotropic plates by using the numerical solution of nonlinear equations, where the velocity term has been removed by employing the fourth sensor. The efficiency and validity of the proposed method has also been experimentally verified.

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Effects of Hydrophilic Additives on the Release Rate of Protein Drugs (단백질 약물 방출속도에 미치는 친수성 첨가제의 영향)

  • Kwon, Young-Kwan;Kim, Ji-Hyeon;Yoo, Young-Je
    • KSBB Journal
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    • v.22 no.4
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    • pp.213-217
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    • 2007
  • It has been reported that hydrophobic additives generally decrease the release rate of protein drugs from drug delivery systems (DDS) and hydrophilic additives increase the release rate. In many cases, however, the addition of hydrophilic molecule is necessary for improving the stability of protein drugs. In the present work, the effects of hydrophilic additives on the release profiles, and micelle formation of protein drug formulations were investigated to develop a novel method for protein drug delivery. For model protein drug, bovine serum albumin (BSA) was employed and several hydrophilic additives were used in the release experiments. Hydrophilic additive D-sorbitol showed the lower release rates of BSA than other hydrophobic additives due to the gel strengthening ability of the additive and the optimum concentration of D-sorbitol was 3 w/v % for the retarded release rate. In addition, it was found that the addition of D-sorbitol was very effective for obtaining homogeneous and stable DDS. The results were discussed in terms of the micelle formation and the micelle structure, i.e., the differences in gel structure and the distribution of drugs in micelles.

Electron Emission Simulation of Carbon Nanotube-based Electron Emitter for Micro Focused X-ray Source

  • Lee, Seung-Ho;Ryu, Je-Hwang;Jung, Gyeong-Bok;Lee, Sung-Hoon;Kim, Kyung-Sook;Park, Hun-Kuk
    • Proceedings of the Korean Vacuum Society Conference
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    • 2011.08a
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    • pp.349-349
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    • 2011
  • 탄소나노튜브의 전자방출 특성을 활용하면 저전압으로 냉전자를 빠른 스위칭 속도로 전자를 용이하게 제어가 가능하다. 이로 인한 고성능 엑스선 소스를 이용하여 의료영상진단과 보안검색 분야에서 많이 사용될 것으로 예상이 된다. 본 연구에서는 고성능 탄소나노튜브 기반 엑스선의 미소초점 형성을 위한 전자 방출 시뮬레이션을 실시하였다. 3극관(애노드, 게이트, 캐소드)에서 2개의 포커싱 전극을 추가한 5극선관의 전자방출 궤적에 대한 시뮬레이션을 진행하였다. 3극관을 구성하여 애노드와 게이트에 일정 전압을 정해준 후, 2개의 포커싱 전극의 전압, 포커싱 전극간의 거리, 그리고 포커싱 전극의 내부직경을 조절함으로써 애노드 상에서의 전자의 초점이 작아지는 것을 알 수 있었다. 마이크로 포커스 엑스레이 소스는 의료영상진단에 있어서 고해상도 의료기기로의 응용이 가능하다.

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An Experimental Investigation of the Underwater Oil Drop Formation (수중으로 방출되는 유류의 유적화에 관한 실험연구)

  • Song Museok
    • Journal of the Korean Society for Marine Environment & Energy
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    • v.6 no.1
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    • pp.3-10
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    • 2003
  • Oil drop formation during the underwater oil discharge is investigated experimentally. The focus is placed on the size of the drops formed with the variation of discharge speed and nozzle diameter. As the Reynolds number based on the nozzle diameter increases, the droplet size decreases first and then increases until an explosive atomization occurs. The length of the jet attached to the nozzle Increases with the Reynolds number and then decreases. The transition occurs when the flow becomes asymmetry.

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Preparation and Evaluation of Antibacterial Transdermal Device using Chitosan Matrices (키토산 매트릭스를 이용한 향균제 경피흡수제형의 제조와 평가)

  • Kim Sun Il;Na Jae Woon
    • Journal of the Korean Chemical Society
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    • v.37 no.5
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    • pp.527-536
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    • 1993
  • The characteristics of the controlled drug release were studied for biodegradable transdermal drug delivery system. A biodegradable polymeric matrix was prepared from chitosan, silver sulfadiazine, and glycerine. The release behavior of silver sulfadiazine from chitosan matrix was consistent with the Higuchi's diffusion controlled model. The release time was delayed by increasing the content of silver sulfadiazine and thickness of the matrix, whereas decreased as glycerine concentration increased. The apparent constant (K) of release rate was proportional to the content of drug or glycerine and the thickness of chitosan matrix. These results indicated that chitosan matrix shows some potential as a drug delivery system for transdermal therapeutic application.

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Hydrogen Storage Properties of Mg-10wt.%MnO Prepared by Reactive Mechanical Grinding (반응성 기계적 분쇄에 의해 제조한 Mg-10wt.% MnO의 수소 저장 성질)

  • Song, Myoung-Youp;Kwon, Ik-Hyun;Kwon, Sung-Nam;Park, Chan-Gi;Bae, Jong-Soo
    • Journal of Hydrogen and New Energy
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    • v.16 no.1
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    • pp.25-30
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    • 2005
  • 수소 분위기에서 10wt.%MnO와 기계적인 분쇄(반응성 기계적 분쇄)에 의해 Mg의 수소 저장 성질을 향상시켰다. 회전 속도는 250 rpm, 밀링시간은 2 h, 그리고 시료 대 볼 중량비는 1/45이었다. 준비한 Mg-10wt.%MnO 시료는 활성화를 위한 수소화물 형성 분해 싸이클링이 필요없었으며, 첫 번째 싸이클 593k 12 bar $H_2$에서, 10분 동안에 3.12wt.%, 60분 동안에 3.95wt.%의 수소를 흡수하였다. 또한 Mg-10wt.%MnO는 593k 0.8 bar $H_2$에서 60분 동안에 2.12wt.%의 수소를 방출하였다. MnO와 Mg의 방응성 분쇄는, 핵생성을 용이케하고 (Mg 입자의 표면에 결함 형성과 첨가물에 의해), Mg 입자의 표면에 crack을 만들어 Mg의 입자 크기를 줄여 그 결과 수소 원자의 확산 거리를 작게 함으로써 수소 흡수 방출 속도를 증가시킨다. 수소화물 형성 분해 싸이클링은 Mg 입자의 표면에 crack을 만들고 Mg의 입자 크기를 줄여 수소 흡수 방출 속도를 증가시킨다.

고밀도 유도 결합형 플라즈마를 이용한 Mo 건식 식각 특성

  • 성연준;이도행;이용혁;염근영
    • Proceedings of the Korean Vacuum Society Conference
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    • 1999.07a
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    • pp.126-126
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    • 1999
  • 본 실험의 목적은 FED의 상부, 하부 전극으로 사용되는 Mo를 건식, 습식 식각함으로써 DED 소자의 공정을 개발하는 것이다. Mo는 $261^{\circ}C$의 높은 융점을 지니고 있으며, 우수한 열적 안정성과 비교적 낮은 비저항을 가지는 재료로써 FED와 같은 전계 방출 소자의 cathod 팁 및 전극물질로 사용되어지는 가장 보편적인 물질이다. FED와 같은 전계방출소자가 갖추어야 할 요건은 전자 방출 영역이 소자 동작시 변형되지 않아야 하고, 기계적 ,화학적, 열적 내구성이 좋아야 함인데 이러한 요건을 충족시킬 수 있고 가장 범용적으로 사용되는 물질이 Mo이다. 실험에서 사용된 Mo는 DC magnetron sputter를 사용하여 Ar 가스를 첨가하여 5mTorr하에서 Si 기판위에 증착속도를 300$\AA$/min로 하여 1.6$\mu\textrm{m}$ 증착하였다. 본 실험의 Mo 식각은 고밀도 플라즈마원인 ICP를 이용하였다. 식각특성은 식각 가스조합, inductive power, bias voltage, 공정 압력의 다양한 공정 변수에 따른 식각특성 변화를 관찰하였다. 식각시 chlorine 가스를 주요 식각 가스로 사용하고 BCl3, O2, Ar을 첨가가스로 사용하였으며, inductive power는 300-600, bias voltage는 120-200V 사용하였고 압력은 15-30mTorr, 기판온도는 7$0^{\circ}C$로 유지하였으며 식각마스크로는 electron-beam evaporator로 1$\mu\textrm{m}$ 증착한 SiO2를 patterning하여 사용하였다. 식각속도는 stylus profiler를 이용하여 측정하였으며 식각후 profile은 scanning electron microscopy (SEM)을 통하여 관찰하였다. 실험 결과 순수한 Cl2 BCl3 가스만을 사용한 경우 보다는 Cl2 가스에 O2를 첨가하였을 때 좋은 선택비를 얻었다. 또한, inductive power와 bias voltage, Mo의 식각속도의 적절한 조절을 통해 SiO2에 대한 선택도를 변화시킬 수 있었다. Cl2:O2비를 1:1로 하고 400W/-150V, 20mTorr의 압력, 7$0^{\circ}C$ 기판온도에서 식각시 200$\AA$/min의 Mo 식각속도, SiO2와의 선택비 8:1을 얻을 수 있었다. 또한 실제 FED 소자 구조형성에 적용한 결과 비등방적인 식각형상을 형성할 수 있었다.

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A Research on the Static Discharger Installation Design and Test for Air Vehicle (항공기 외표면 정전기 방출기 장착설계 및 시험에 관한 연구)

  • Woo, Hee-Chae;Kim, Yong-Tae;Kim, Bong-Gyu
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.45 no.7
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    • pp.574-580
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    • 2017
  • Static dischargers should be installed on air vehicle to emit a static electricity during flight. Especially, If static electricity is not removed by static discharger on the air vehicle, it makes ionization and corona effect on the edge of antenna and wing. Those phenomenon bring about performance degradation for radio communication and equipment operation. In this paper, the conditions such as climate, air vehicle's speed and frontal area were analyzed to design static dischargers. As a result, the static dischargers would be optimally designed for air vehicles and the performance of the static dischargers can verify according to the functional experiment. Therefore the result of this research will be used to make static discharger installation design for new air vehicle that have different size and mission.

Changes of Inorganic Nitrogen and CO2 Evolution Rate on the Decomposition Process of Korean White Pine Needles (잣나무엽(葉)의 초기(初期) 분해과정(分解過程)에 있어서 무기태(無機態) 질소(窒素) 및 CO2 방출속도(放出速度)의 변화(變化))

  • Yi, Myong Jong;Han, Sang Sup;Kim, Jeong Je
    • Journal of Korean Society of Forest Science
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    • v.69 no.1
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    • pp.13-18
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    • 1985
  • Forest soils mixed with organic matters (green needle, flesh needle litter and needle litter in F layer of Pinus koraiensis, and green leaf of Quercus dentata and Q. variabilis) were incubated under a constant $30^{\circ}C({\pm}1)$ for 53 days to measure the changes of inorganic nitrogen and $CO_2$ evolution rate. The results obtained were summarized as follows; 1) In the early incubation period the amounts of total inorganic nitrogen in soils by mixture of organic matters decreased rapidly because of immobilization by microbial uptake, and thereafter their amounts increased with further incubation. 2) The rate of immobilization of organic nitrogen in mixed organic matters was the highest in green needle among green needle, flesh needle litter and needle litter in F layer of P. koraiensis, but lower than that of green leaf of Q. variabilis and Q. dentata. 3) The rates of $CO_2$ evolution from soils mixed with organic matters increased sharply in the early time, and then decreased slowly with increasing time. The order of the $CO_2$ evolution rate was green leaf of Q. variabilis > green leaf of Q. dentata > green needle of P. koraiensis > flesh needle litter of P. koraiensis > needle litter of P. koraiensis in F layer from the largest to the least. 4) Nitrate nitrogen concentrations showed a tendency to increase throughout incubation time, so that their concentrations after 53 days were higher than that of ammonium nitrogen.

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