• Title/Summary/Keyword: 방사선 분해

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Design of Gamma Camera with Diverging Collimator for Spatial Resolution Improvement (공간분해능 향상을 위한 확산형 콜리메이터 기반의 감마카메라 설계)

  • Lee, Seung-Jae;Jang, Yeongill;Baek, Cheol-Ha
    • Journal of the Korean Society of Radiology
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    • v.13 no.4
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    • pp.661-666
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    • 2019
  • Diverging collimators is used to obtain reduced images of an object, or to detect a wide filed-of-view (FOV) using a small gamma camera. In the gamma camera using the diverging collimators, the block scintillator, and the pixel scintillator array, gamma rays are obliquely incident on the scintillator surface when the source is located the periphery of the FOV. Therefore, the spatial resolution is reduced because it is obliquely detected in depth direction. In this study, we designed a novel system to improve the spatial resolution in the periphery of the FOV. Using a tapered crystal array to configure the scintillation pixels to coincide with the angle of the collimator's hole allows imaging to one scintillation pixel location, even if events occur to different depths. That is, even if is detected at various points in the diagonal direction, the gamma rays interact with one crystal pixel, so resolution does not degrade. The resolution of the block scintillator and the tapered crystal array was compared and evaluated through Geant4 Application for Tomographic Emission (GATE) simulation. The spatial resolution of the obtained image was 4.05 mm in the block scintillator and 2.97 mm in the tapered crystal array. There was a 26.67% spatial resolution improvement in the tapered crystal array compared to the block scintillation.

Study on the Degradation of Pigskin Collagen Using Irradiation Technique (방사선조사를 이용한 돈피 콜라겐의 저분자화 연구)

  • Cho, Young-Jun;Seo, Jung-Eun;Kim, Yun-Ji;Lee, Nam-Hyouk;Hong, Sang-Pil;Kim, Young-Ho
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.35 no.5
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    • pp.588-593
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    • 2006
  • This study was intended to observe possibility of which radiation technique can be used for oligopeptide production from pigskin collagen to reduce environmental pollution in processing and simplify the processing steps. Raw pigskin was ground using chopper, and then defatted in acetone cooled at $-20^{\circ}C$ freezer. Defatted dried pigskin was irradiated at 20, 40, 60, 100, 150, 200, 250, and 300 kGy using Co-60 gamma rays irradiator. With irradiation doses, the amount of soluble proteins increased, and the viscosity and turbidity of soluble proteins decreased, which could be clue of that irradiation degrade high molecular proteins directly. pH of soluble proteins from defatted pigskin increased in the sample above 150 kGy, and low molecular weight components (below 24 kDa) in SDS-PAGE increased. From gel permeation chromatography of the hydrolysates of pigskin irradiated at 300 kGy showed the major peak of 9,000, 8,200, 860, and 170 Da.

A Study on Treatment Target Position Verification by using Electronic Portal Imaging Device & Fractionated Stereotatic Radiotherapy (EPID와 FSRT를 이용한 치료표적위치 검증에 관한 연구)

  • Lee, Dong-Hoon;Kwon, Jang-Woo;Park, Seung-Woo;Kim, Yoon-Jong;Lee, Dong-Han;Ji, Young-Hoon
    • Journal of the Institute of Electronics Engineers of Korea SC
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    • v.46 no.3
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    • pp.44-51
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    • 2009
  • It is very important to verify generated setup errors in cancer therapy by using a high energy radiation and to perform the precise radiation therapy. Specially, the verification of treatment position is very crucial in special therapies like fractionated stereotatic radiotherapy (FSRT). The FSRT uses normally high-dose, small field size for treating small intracranial lesions. To estimate the developed FSRT system, the isocenter accuracy of gantry, couch and collimator were performed and a total of inaccuracy was less than ${\pm}1mm$. Precise beam targeting is crucial when using high-dose, small field size FSRT for treating small intracranial lesions. The EPID image of the 3mm lead ball mounted on the isocenter with a 25mm collimator cone was acquired and detected to the extent of one pixel (0.76mm) after comparing the difference between the center of a 25mm collimator cone and a 3 mm ball after processing the EPID image. In this paper, the radiation treatment efficiency can be improved by performing precise radiation therapy with a developed video based EPID and FSRT at near real time

Quantitative Comparison of 2-Alkylcyclobutanones from Raw Egg Yolk, Boiled Egg Yolk, and Egg Yolk Powder (생난황, 삶은 난황 및 난황분에서 방사선 조사에 의해 유도된 2-Alkylcyclobutanone류의 정량적 비교 분석)

  • 서혜영;김경수
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.33 no.1
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    • pp.158-163
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    • 2004
  • We investigated the usefulness of 2-alkylcyclobutanones as markers for irradiated eggs and egg products by comparing 2-alkylcyclobutanone concentrations in irradiated raw egg yolk, boiled egg yolk, and egg yolk powder. One method of detection radiation-induced 2-alkylcyclobutanones involves extraction fat from irradiated egg samples separating 2-alkylcyclobutanones by florisil column chromatography, and identifying GC/MS. 2-(5'-Tetradecenyl)cyclobutanone of 2-alkylcyclobutanones was high relatively in boiled egg yolk, but 2-dodecylcyclobutanone was high in raw egg yolk and egg yolk Powder. Concentrations of the radiation-induced 2-alkylcyclobutanones increased linearly with the irradiation dose. The radiation-induced 2-alkylcyclobutanones from egg samples at 0.5 kGy over and not detected at the non-irradiated samples. Therefore, these compounds could be used as marker of Post-irradiation for egg Products.

Effects of Low-Dose Fractionated Total Body Irradiation on Murine Immune System (마우스에서 전신 저선량 분할 방사선 조사에 의한 면역학적 변화 평가)

  • Kim, Mi-Hyoung;Rhu, Sang-Young;Lim, Dae-Seog;Song, Jie-Young
    • Journal of Radiation Protection and Research
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    • v.39 no.3
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    • pp.134-141
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    • 2014
  • Along with the wide use of radiotherapy in cancer treatment, there is growing interest in beneficial effect of low-dose irradiation (LDI) in cancer therapy. Therefore, we investigate how LDI affects immune responses in mice model. Total body irradiation (TBI) on C57BL/6 mice was given at low-dose rate of $1mGy{\cdot}min^{-1}$ using $^{137}Cs$ source at three times for consecutive three days. Hematological examination, total cell numbers of spleen, populations and characteristics of splenocytes were determined. Total numbers of RBC or platelet in irradiated mice showed no significant changes. WBC counts were decreased in a dose-dependent manner 2 days after TBI, however, these differences are gradually waned until 28 days. Dose-dependent decrease in the number of splenocytes of TBI mice at day 2 was also improved as time progressed. While the level of Foxp3 mRNA was decreased, the frequency of $CD4^+$ T cells and $CD69^+$ cells in spleen was increased at day 2 and 14. Fractionated low-dose TBI on mice exhibited normal body weight with no distinguishable behavior during whole experimental periods. These results suggest that some parameters of immune system could be altered and evaluated by fractionated low-dose TBI and be used to broaden boundary of low dose radiation research.

Quantitative Analysis of Spatial Resolution for the Influence of the Focus Size and Digital Image Post-Processing on the Computed Radiography (CR(Computed Radiography)에서 초점 크기와 디지털영상후처리에 따른 공간분해능의 정량적 분석)

  • Seoung, Youl-Hun
    • Journal of Digital Convergence
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    • v.12 no.11
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    • pp.407-414
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    • 2014
  • The aim of the present study was to carry out quantitative analysis of spatial resolution for the influence of the focus size and digital image post-processing on the Computed Radiography (CR). The modulation transfer functions of an edge measuring method (MTF) was used for the evaluation of the spatial resolution. The focus size of X-ray tube was used the small focus (0.6 mm) and the large focus (1.2 mm). We evaluated the 50% and 10% of MTF for the enhancement of edge and contrast by using multi-scale image contrast amplification (MUSICA) in digital image post-processing. As a results, the edge enhancement than the contrast enhancement were significantly higher the spatial resolution of MTF 50% in all focus. Also the spatial resolution of the obtained images in a large focus were improved by digital image processing. In conclusion, the results of this study should serve as a basic data for obtain the high resolution clinical images, such as skeletal and chest images on the CR.