• 제목/요약/키워드: 방사선학적 변화

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Quality Changes of Kimchi Manufactured with Sanitized Materials by Ozone and Gamma Irradiation during Storage (오존 및 방사선 조사기술 이용 원부재료의 위생화 후 제조한 김치의 저장기간에 따른 변화)

  • Lee, Kyong-Haeng;Byun, Myung-Woo
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.36 no.2
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    • pp.216-221
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    • 2007
  • Microbiological, chemical and sensorial quality changes of kimchi, which was manufactured with sanitized materials by ozone and gamma irradiation, were investigated during storage. The number of total aerobic bacteria in control was increased rapidly by storage and decreased after 10 days of storage. However, the kimchi which was manufactured with materials treated with ozone or gamma irradiation showed a lower rate of increase. The number of lactic acid bacteria was lower in control than in treatments. Gamma irradiation of 3 or 5 kGy showed the lowest change of microbial population in kimchi during storage. pH, acidity and sensory quality were also rapidly changed in control whereas those of ozone or irradiation treated sample was slower. Therefore, cold pasteurization of materials before kimchi manufacturing provide a slower fermentation, resulting into the extension of storage quality for kimchi.

The Effect of Splinting with Concomitant Root Planing;Clinical and Digital Subtraction Radiographic Study (치근활택술과 스프린트 병행처치의 효과에 관한 연구;디지털 공제 촬영술을 이용한 임상적 연구)

  • Lee, Ji-Young;Kye, Seung-Bum;Kim, Won-Kyoung;Lee, Yong-Moo;Ku, Young;Ryu, In-Chul;Chung, Chong-Pyoung;Choi, Sang-Mook;Han, Soo-Boo
    • Journal of Periodontal and Implant Science
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    • v.31 no.1
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    • pp.207-227
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    • 2001
  • 스프린트는 치주처지료에서 부가적 처치법으로 널리 사용되고 있으며, 한편, 디지털 공제 활영술은 기존방사선촬영술의 한계점을 극복하기 위해 기발된 새로운 방법이다. 이번 연구에서는 치근활택술 단독시행시와 스피린트 병행 처치시의 효과를 임상적, 방사선학적으로 비교하였다. 중정도의 성인성 치주염을 가진 20명의 환자를 대상으로 하되 10명은 치근활택술 단독으로, 나머지 10명은 스프린트 병행처치로 처치하였다. 임상적, 방사선학적인 평가는 처치전, 처치후 6개월에 행하고, 임상적 평가의 경우 3개월에 추가로 실시하였다. 이번 연구에서 사용된 임상 지수로는 치태지수, 치은지수, 치은퇴축, 치주낭깊이, 임상부착수준, 임상부착증가, 탐침시출혈, 치아동요도 등이며, 방사선학적 평가는 기존 방사선촬영술에 의한 방법과 디지털 공제촬영수렝 의한 방법으로 행하였다. 디지털 공제 촬영술에 의한 평가시, 영상은 Digora 프로그램에 의해 획득하고 Emago 프로그램으로 처리 하여 다음과 같은 결론을 얻었다. 1. 처치후 3개월에 치태지수, 치은지수, 치은퇴축, 치주낭깊이, 임상적부착수준, 탐침시 출혈 등의 임상지수들이 변했으며, 특히 이러한 변화는 치주낭깊이, 치은퇴축, 탐침시출혈에서 유의성이 있었다. ( p<0.05 ) 그러나 두군간 차이는 인정되지 않았다. ( p>0.05 ) 2. 처치후 6개월에도 치태지수, 치은지수, 치은퇴축, 치주낭깊이, 임상적부착수준, 탐침시출혈, 치아동요도 등의 임상지수들이 변했으며, 특히 이러한 변화는 치주낭깊이, 치은퇴축, 탐침시출혈, 치태지수, 치아동요도에서 유의성이 있었다. ( p<0.05 ) 그러나 두 군간 차이는 인정되지 않았다. ( p>0.05 ) 3. 켄달 상관분석시, 임상적 평가와 기존 방사선 촬영술에 의한 평가사이의 관련성을 낮았으며 거의 0에 가까운 수치를 보였으며 (r=0.110, p=0.639 ) 임상적 평가와 디지털 공제 방사선 촬영술에 의한 평가사이에서 약간 높은 관련성을 보였다. ( r=0.257, p=0.315 ) 즉 치주치료후의 골변화는 디지털 공제 방사선 촬영술에 의한 평가시 기존 방사선 사진보다 임상적 부착증가와 더욱 긴밀한 관련성을 보여준다. 이상의 결과로 볼 때, 스프린팅 처치는 치주 치료에 있어 치근활택술에 부가적 표과를 제공하지 못한다.

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The Effect of Ionizing Radiation on the Ultrastructural Changes and Mechanism on the Cytoplasmic Organelles (전리방사선이 세포질 소기관의 미세구조변화와 기전에 미치는 영향)

  • Lee, Moo Seok;Lee, Jong Kyu;Nam, Ji Ho;Ha, Tae Yeong;Lim, Yeong Hyeon;Kil, Sang Hyeong
    • Journal of Life Science
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    • v.27 no.6
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    • pp.708-725
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    • 2017
  • Ionizing radiation is enough energy to interact with matter to remove orbital electrons, neutrons, and protons in the atom. Ionizing radiation like this leads to oxidizing metabolism that alter molecular structure through direct and indirect interactions of radiation with the deoxyribonucleic acid in the nucleus and cytoplasmic organelles or via products of cytoplasm radiolysis. These ionization can result in tissue damage and disruption of cellular function at the molecular level. Consequently, ionizing radiation-induced modifications of ion channels and transporters have been reported. When the harmful effects exceed those of homeostatic biochemical processes, induced biological changes persist and may be propagated to progeny cells. Also, Reactive oxygen species formed on the effect of ionizing radiation can get across into neighboring cells through the cell junctions that are responsible for intercellular chemical communication, and may there bring about changes characteristic to radiation damage. Depending on radiation dose, dose-rate and quality, these protective mechanisms may or may not be sufficient to cope with the stress. This paper briefly reviewed reports on ionization radiation effects on cellular level that support the concept of radiation biology. A better understanding of the biological effects of ionizing radiation will lead to better use of and better protection from radiation.

Cytokinesis-blocked micronuclei in the human peripheral lymphocytes following low dose γ-rays irradiation (저선량의 감마선 피폭된 사람 말초 임파구의 미소핵을 이용한 방사선 생물학적 피폭선량 측정법 연구)

  • Kim, Tae-hwan
    • Korean Journal of Veterinary Research
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    • v.41 no.1
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    • pp.99-104
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    • 2001
  • To determine if micronucleus (MN) assay could be used to predict the absorbed dose of victims after accidental radiation exposure, we carried out to assess the absorbed dose depending on the numerical changes of MN in human peripheral blood lymphocytes after $^{60}Co\;{\gamma}-rays$ exposure in the range of 0.25 to 1 Gy, respectively. The MNs were observed at very low doses, and the numerical changes according to doses. Satisfactory dose-effect calibration curve is observed after low dose irradiation of human lymphocytes in vitro. When plotting on a linear scale against radiation dose, the line of best fit was $Y=(0.02{\pm}0.0009)+(0.033{\pm}0.010)D+(0.012{\pm}0.012)D^2$. The dose-response curve for MN induction immediately after irradiation was linear-quadratic and has a significant relationship between the frequencies of MN and dose. These data show a trend towards increase of the numbers of MN with increasing dose. The number of MN in lymphocytes that were observed in the control group is $0.1610{\pm}0.0093/cell$. Accordingly, MN assay in human peripheral lymphocytes could be a useful in viva model for studying radio-protective drug sensitivity or screening test, microdosimertic indicator and radiation-induced target organ injury. Since MN assay is simple, rapid and reproducible, it will also be a biodosimetric indicator for individual dose assessment after accidental exposure.

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The Radiologic and Clinical Changes after Open Complete Repair of Massive Rotator Cuff Tears (개방적 완전 봉합술로 치료한 광범위 회전근 개 파열 환자에서 치료 전후의 방사선학적 및 임상적 소견의 변화)

  • Moon, Eun-Sun;Choi, Min-Sun;Kim, Myung-Sun;Kong, Il-Kyu;Kim, Byoung-Jin
    • Clinics in Shoulder and Elbow
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    • v.12 no.2
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    • pp.109-114
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    • 2009
  • Purpose: This study evaluated the preoperative and postoperative radiologic findings of patients with complete repairs after massive rotator cuff tears along with the incidence of re-tear and the clinical outcomes. Materials and methods: This study evaluated 33 cases who had open complete repairs for massive rotator cuff tears and these patients were followed up for more than 24 months. The clinical evaluation was performed according to the shoulder joint function test of the American Shoulder and Elbow Surgeons (ASES), and the degree of arthritis related to the massive rotator cuff tears was evaluated using the Hamada classification. Results: The ASES scores improved from 37.6 preoperatively to 85.6 postoperatively. The mean preoperative acromio-humeral interval (AHI) score was 6.5 mm, which increased to 9.3 mm immediately after surgery, and there was a decreased to 6.5 mm noted at the last follow up. The lower radiology stages of arthritis according to the classification showed better preoperative and postoperative results. Conclusion: An open complete repair as the surgical treatment for a massive rotator cuff tear showed satisfactory results for pain relief and an improvement in the shoulder joint function though re-tear after surgery.

Study of Histochemical Changes of Mouse Ovary Under X-ray Irradiation (방사선 조사선량에 따른 생쥐 난소의 조직화학적 변화)

  • Yoon, Chul-Ho
    • Journal of radiological science and technology
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    • v.29 no.4
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    • pp.275-284
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    • 2006
  • This research investigated the morphological changes of folliculus ovary according to the dose of the X-rays when mice were exposed to X-rays, in terms of histochemical reaction. Dyeing methods such as Masson's trichrome method and reticular fiber method were used. The morphological changes of growing folliculus ovary got distinct as the dose of X-rays increased. Especially, the nuclei of granular cells showed manifest condensation and the changes of the transparent zone were distinct. As a result of histochemical reaction according to Masson's trichrome method and reticular fiber method, the changed granular cells, the deformed basilar membrane of folliculus ovary and the abnormal arrangement of the reticular fiber were observed.

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Anatomy Based maxillofacial Surgery Planning System (해부학적 지식에 기반한 악안면 기형수술 예측 시스템)

  • 김영인;박정현;김수균;김창헌
    • Proceedings of the Korean Information Science Society Conference
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    • 2000.04b
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    • pp.646-648
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    • 2000
  • 본 논문은 악안면 기형 환자의 해부학적 구조를 기반으로 하여 임상적으로 수술 결과 영상을 생성하는 방법을 제시한다. 이 방법은 환자의 평면 방사선 사진으로부터 환자의 경조직과 연조직의 외곽선을 추출하고, 이를 바탕으로 연조직 이동량 예측 함수를 이용함으로써 환자의 해부학적 특성을 고려한 가상 수술을 수행한다. 예측함수는 경조직 특징점 8개의 이동량에 따른 연조직 특징점 10개의 변화량을 함수로 만든 것으로, 100명의 임상 결과를 바탕으로 도출한 것이다. 또한 환자의 평면 방사선 사진과 특징 부위의 외곽선, 그리고 환자의 외형사진을 쉽게 정합하는 인터페이스를 제공함으로써, 환자의 가상 수술 후 결과를 평면 방사선 사진 및 측면사진으로 표현하는 특징이 있다.

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The Effect of Irradiation and Cis-diamminedichloroplatinum(II) in the Rat Brain : Analysis of Histopathology at 3 and 6 Months after Treatment (횐쥐 뇌에 방사선조사와 Cis-diamminedichloroplatinum(II)의 효과 : 치료 후 3개월과 6개월에서의 조직학적분석)

  • Lee Kyung-Ja;Chang Seung-Hee;Koo Heasoo
    • Radiation Oncology Journal
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    • v.16 no.2
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    • pp.125-138
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    • 1998
  • Purpose : To evaluate the late effect(3 and 6 months) of cis-diarnrninedichlo-roplatinum(II)(cisplatin) on the radiation brain damage when the cisplatin was intraperitoneally infused immediately after whole brain irradiation in the rats. Materials and Methods : The histolopathological findings of the brain were examined in rat brains at 3 and 6 months after the treatment. The rats were irradiated(20 or 22.5 Gy, RT) or cisplatin was injected intraperitoneally(2,4, or 8mg/kg, CT) and in combined treatment group, cisplatin(2mg/kg) was injected immediately after irradiation(20 or 22.5 Gr). Histopathological examination was done mostly in irradiation or cisplatin alone groups, because the rats in combined group died during experimental period except 2 rats. Results : The rats treated with cisplatin showed marked epithelial vacuolation with perivascular edema and vascular dilatation in choroid plexus at 3 months as well as multifocal necrosis involving fimbria and cerebellar hemispheres at 3 and 6 months. The changes were more prominent in rats with 2mg/kg injection compared to rats with 8mg/kg injection. The rats with RT and combined CT and RT showed characteristic delayed irradiation effects such as focal coagulation necrosis and vascular changes, which were more marked than previous reports Prominent perivascular and leptomenin-geal astrocytic Proliferation was well documented by anti-GFAP antibody. Cisplatin treatment did not enhance the effect of radiation-induced changes of blood vessels and astrocytic proliferation. Conclusion : The focal necrosis was the most consistently noted finding in this study, it suggested the possibility to use this as an evaluation factor for combined effects of RT and cisplatin.

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