• Title/Summary/Keyword: 방사능 값

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A study of Brain Micro-PET Imaging and Bindingpotential with a Different Specific Activity of 18F-Fallypride in the Small Animal (소동물에서 18F-Fallypride의 비방사능에 따른 뇌의 PET이미지와 Binding Potential 차이에 대한 연구)

  • Cho, Kyu-Sang;Ahn, Sung-Min
    • The Journal of the Korea Contents Association
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    • v.15 no.9
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    • pp.418-424
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    • 2015
  • In this study, we proceed if there are any changes in binding ability of receptor-ligand in some degree of SA and in radioactive uptake from the corpus striatum based on small animal experiment in vivo based on the S.A values. By dividing 18F-Fallypride into 3 S.A values(high S.A : 43.29~74 GBq/umol, ordinary S.A : 20.72~29.23 GBq/umol, low S.A : 6.29~8.51 GBq/umol), we injected directly into the veins and performed 90 minutes of dynamic scan using Micro PET. After scanning, we compared and analyzed with Binding Potential (Binding Potential) from the bilateral striatum. high SA and low SA, ordinary SA and low SA showed significant differences. Also, in the image comparison using 18F-Fallypride show high radioactive uptake in the striatum at high SA and ordinary SA, but the radioactive uptake at low SA is lower than other two SA. Since 18F-Fallypride has affinity to dopamine D2/3 pharmacokinetic, the difference of Binding Potentials at decreased level of SA values was not that significant. However, further PET research of the corpus striatum using 18F-Fallypride is necessary because the differences in images and Binding Potentials at 6.5 times smaller SA values compared to high SA value showed were significant.

Measurement of Ir-192 Source Activity for High Dose Rate Brachytherapy (고 선량률 근접치료시 사용되는 Ir-192 선원의 방사능 평가)

  • 최동락;허승재;안용찬;임도훈;김대용;우홍균
    • Progress in Medical Physics
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    • v.8 no.1
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    • pp.25-29
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    • 1997
  • Ir-192 source activity for high dose rate brachytherapy is measured using Farmertype ionization chamber. The source-to-chamber distance is 10 cm and the measured charge unit is converted to activity unit. The measured values are compared to the values provided from vendor. Because of time dependency of Ir-192 source activity, the activities are regularly checked and compared to calculated values. As the accuracy of Ir-192 source activity is depend on the mechanical measurement setup, we estimated the precision of remote controlled source dwell position using home-made device and film scanner. The difference between measured and predicted dwell position is within 1 mm. As a result, the errors of source activity are 0.7${\pm}$1.5 % for measured and vendor-provided values and 0.l${\pm}$1.2% for measured and time-dependent calculated vlaues. In conclusion, our measured activity has been comparable to the values provided from vendor and our brachytherapy unit has been very accurate until now. Regular quality control of brachytherapy is essential for successful treatment which depends on the accuracy of source position and activity.

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Uncertainty Analysis of the Calculated Radioactivity in Liquid Effluent Released as Batch Mode from a Nuclear Power Plant (발전용원자로에서 뱃치방식으로 배출되는 액체상 방사성물질의 방사능 평가결과에 대한 불확도 해석)

  • 정재학;박원재
    • Proceedings of the Korean Radioactive Waste Society Conference
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    • 2003.11a
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    • pp.562-571
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    • 2003
  • A series of factors such as sampling, pretreatment measurement, volume estimation which induces uncertainty of the calculated radioactivity in liquid effluent released from a nuclear power plant were analyzed. It is innately impossible to estimate exact error of the calculated radioactivity, since most of the input parameters are determined by a single measurement and true value of the released radioactivity cannot be known. In this paper, a systematic model to calculate uncertainty of the released liquid radioactivity was developed based upon the guidance report published by the ISO in 1993, and the model was applied to a set of hypothetical batch release conditions. As a result, the Priority of each input parameter was turned out to be (1) wastewater volume, (2) sample volume, and (3) measured radioactivity of the sample. In addition, probability distribution of the released radioactivity was simulated by Monte Carlo method combining the probability distribution of each input parameter It was shown that the radioactivity released to the environment, which has been reported as a single value, has a certain form of probability distribution.

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하나로를 이용한 근접치료용 Ir-192 Seed의 제조

  • 조운갑;한현수;박울재;이영구;전상수
    • Proceedings of the Korean Nuclear Society Conference
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    • 1997.05b
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    • pp.373-378
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    • 1997
  • 시험가동중인 다목적연구용 '하나로'를 이용하여 근접치료용으로 사용되는 $^{192}$ IR seed 제조실험을 하였다. '하나로'의 특성을 고려하여 제작된 조사표적용기에 표적용 Ir seed를 넣고 밀봉한 후 He 누출시험을 통과한 표적만 원자로의 HTS 조사공에서 중성자 조사시켰다. HTS 조사공의 평균 열중성자속은 측정결과 원자로출력 15 MWt일 때 2.54 $\times$ $10^{13}$ n/$\textrm{cm}^2$.sec였다. 5회에 걸쳐 5개의 조사표적을 사용하여 총 200개의 $^{192}$ Ir seed를 제조, 실험하였으며 2시간 조사후 14일간 냉각시킨 Ir seed의 r-ray spectrum을 분석한 결과 $^{l92}$Ir외의 불순핵종은 검출되지 않았다. Ir seed의 방사능은 이온전리함을 사용하여 측정하였으며 방사능 측정결과 개별 $^{192}$ Ir seed의 방사능값은 평균 방사능값으로부터 $\pm$5 % 이내오차의 방사능 균일도를 갖는 것이 확인되었다.차의 방사능 균일도를 갖는 것이 확인되었다.

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삼중수소 전처리과정이 방사능 측정결과에 미치는 영향평가

  • Lee, Byeong-Il;Jeong, Jin-Uk;Choe, Yeong-Hun
    • 대한방사선방어학회:학술대회논문집
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    • 2010.04a
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    • pp.82-83
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    • 2010
  • 환경시료 중 삼중수소의 방사능을 분석하기 위하여 전처리과정을 수행한다. 전처리의 주요 절차는 증류와 발광액의 첨가 그리고 약 24시간의 암실보관 등이다. 본 보고서에서는 각 전처리 과정이 방사능 측정결과에 미치는 영향을 평가하고 전처리과정에서 피할 수 없는 오차와의 관계를 확인한 후 이를 통해 삼중수소의 방사능 세기에 따라 전처리과정의 상대적 중요도를 확인하고자 한다. 이 과정을 통해 전처리가 꼭 필요한 경우와 그렇지 않은 경우를 구분할 수 있는 방사능 세기의 문턱 값을 확인하고자 한다.

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Quality Control of Radiation Counting Systems and Measurement of Minimum Delectable Activity (방사선 계측기의 품질관리 및 최소검출방사능 측정)

  • 송병철;한성심;김영복;지광용;손세철
    • Proceedings of the Korean Radioactive Waste Society Conference
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    • 2004.06a
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    • pp.419-424
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    • 2004
  • Various radiation counters have been using to determine radioactivity of radwastes for disposal. A radiation counting system was set up using a radiation detector chosen in this study and its stability was investigated through the periodic determination of background and counting efficiencies in accordance with a quality control program to increase the confidence level. The average background level for the $\gamma$-spectrometer was 1.59 cps and the average counting level for the standard sample was 45248 Ops within $2{\sigma}$ confidence levels. The average alpha background level for the low background ${\alpha}{\beta}$ counting system was 0.31 cpm and the efficiency for alpha counting was 34.38%. The average beta background level for the ${\alpha}{\beta}$ counting system was 1,30 cpm and the efficiency for beta counting was 46.5%, The background level in the region of 3H and 14C for the liquid scintillation counting system was 2.52 and 3.31 cpm and the efficiency for alpha counting was 58.5 and 95.6%, respectively. The minimum detectable activity for the$\gamma$-spectrometer was found to be 3.2 Bq/$m\ell$ and 3.8 Bq/$m\ell$ for the liquid scintillation counter, and 20.5 and 23.0 Bq/$m\ell$, respectively for the $\alpha$ and $\beta$ counting system.

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Determination of Minimum Detectable Activity in Environmental Samples (환경방사능 측정에서의 검출한계치의 정량적 고찰 및 최소검출방사능 농도 계산)

  • Lee, Myung-Ho;Shin, Hyun-Sang;Hong, Kwang-Hee;Cho, Young-Hyun;Lee, Chang-Woo
    • Journal of Radiation Protection and Research
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    • v.24 no.3
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    • pp.171-184
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    • 1999
  • In this paper, using statistical theory the basic concepts and the formulars of lower limit of detection were deasribed. Assuming that risks of 5% are acceptable (95% confidence level), lower limits of detection were calculated on the measuring apparatus for alpha, beta and gamma nuclides. Also, on the basis concepts of lower limit of detection, the MDA values were calculated for the radionuclides detected easily in the environment. These results make it possible to evaluate confidence limits on the radioanalytical results in the environmental sample.

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Radioactivity Analysis for Reliability Assessment in the Environmental Samples (환경 시료 중 신뢰도 검증을 위한 방사능 분석)

  • Kang, Tae-Woo;Hong, Kyung-Ae
    • Korean Journal of Environmental Agriculture
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    • v.26 no.2
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    • pp.186-191
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    • 2007
  • The objective of this research was to assess the reliability of data and to improve nuclear analytical techniques concerning the Domestic Radioactivity Intercomparison program for environmental radioactivity monitoring of Jeju from 1998 to 2006. Gross beta for filter papers and water samples was determined, and gamma nuclides for natural and artificial nuclides in soil and water samples were analyzed. The gross beta activity of all samples except for the water samples of 1998 and 1999 showed a good agreement within the confidence intervals. In gamma nuclides, $^{40}K$ and $^{137}Cs$ of soil samples and most nuclides in the water samples, with the exception of several nuclides, were evaluated to be reliable. Based on these results, it is considered that a reliable method for the analysis and monitoring of environmental radioactivity were established, which may play an important role in case of emergency radiation accident.

Survey of radioactive contamination in imported foodstuffs (수입 식품중의 방사능 오염실태 조사)

  • Lee, Wan-No;Lee, Haeng-Pil;Chung, Kun-Ho;Kim, Hee-Reyoung;Cho, Young-Hyun;Choi, Geun-Sik;Lee, Chang-Woo;Chung, Hyung-Wook;Lee, Eun-Ju;Sho, You-Sup;Lee, Jong-Ok
    • Journal of Radiation Protection and Research
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    • v.31 no.3
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    • pp.141-148
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    • 2006
  • Surveys of radioactive contamination were performed for imported foodstuffs in 2003. The following samples among imported foodstuffs were selected from markets and Korea Food and Drug Administration(KFDA); the imported samples from country associated with the Chernobyl nuclear accident, the samples produced around the nuclear power plants or nuclear tests, the foodstuffs reported as radioacitive contamination materials in foreign country. After pretreatments such as drying and homogenization, samples were analyzed. The $^{137}Cs$ radionuclide was only measured among the regulation radionuclides($^{137}Cs,\;^{134}Cs,\;^{131}I$) of food code. All foodstuffs except Inonotus Obliquus(Chaga mushooms) are less than 17.0 Bq/kg or below the minimum detectable activity(MDA). The activity concentrations of Chaga mushrooms from Russia ranged up to 131.25 Bq/ltg which is almost 35 % of the maximum permitted level of food code. The fraction of imported foodstuffs having meaningful radioactivity is small, however, the radioactive contamination survey of imported foodstuffs is still needed.

The Evaluation of SUV Variations According to the Errors of Entering Parameters in the PET-CT Examinations (PET/CT 검사에서 매개변수 입력오류에 따른 표준섭취계수 평가)

  • Kim, Jia;Hong, Gun Chul;Lee, Hyeok;Choi, Seong Wook
    • The Korean Journal of Nuclear Medicine Technology
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    • v.18 no.1
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    • pp.43-48
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    • 2014
  • Purpose: In the PET/CT images, The SUV (standardized uptake value) enables the quantitative assessment according to the biological changes of organs as the index of distinction whether lesion is malignant or not. Therefore, It is too important to enter parameters correctly that affect to the SUV. The purpose of this study is to evaluate an allowable error range of SUV as measuring the difference of results according to input errors of Activity, Weight, uptake Time among the parameters. Materials and Methods: Three inserts, Hot, Teflon and Air, were situated in the 1994 NEMA Phantom. Phantom was filled with 27.3 MBq/mL of 18F-FDG. The ratio of hotspot area activity to background area activity was regulated as 4:1. After scanning, Image was re-reconstructed after incurring input errors in Activity, Weight, uptake Time parameters as ${\pm}5%$, 10%, 15%, 30%, 50% from original data. ROIs (region of interests) were set one in the each insert areas and four in the background areas. $SUV_{mean}$ and percentage differences were calculated and compared in each areas. Results: $SUV_{mean}$ of Hot. Teflon, Air and BKG (Background) areas of original images were 4.5, 0.02. 0.1 and 1.0. The min and max value of $SUV_{mean}$ according to change of Activity error were 3.0 and 9.0 in Hot, 0.01 and 0.04 in Teflon, 0.1 and 0.3 in Air, 0.6 and 2.0 in BKG areas. And percentage differences were equally from -33% to 100%. In case of Weight error showed $SUV_{mean}$ as 2.2 and 6.7 in Hot, 0.01 and 0.03 in Tefron, 0.09 and 0.28 in Air, 0.5 and 1.5 in BKG areas. And percentage differences were equally from -50% to 50% except Teflon area's percentage deference that was from -50% to 52%. In case of uptake Time error showed $SUV_{mean}$ as 3.8 and 5.3 in Hot, 0.01 and 0.02 in Teflon, 0.1 and 0.2 in Air, 0.8 and 1.2 in BKG areas. And percentage differences were equally from 17% to -14% in Hot and BKG areas. Teflon area's percentage difference was from -50% to 52% and Air area's one was from -12% to 20%. Conclusion: As shown in the results, It was applied within ${\pm}5%$ of Activity and Weight errors if the allowable error range was configured within 5%. So, The calibration of dose calibrator and weighing machine has to conduct within ${\pm}5%$ error range because they can affect to Activity and Weight rates. In case of Time error, it showed separate error ranges according to the type of inserts. It showed within 5% error when Hot and BKG areas error were within ${\pm}15%$. So we have to consider each time errors if we use more than two clocks included scanner's one during the examinations.

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