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Small CNN-RNN Engraft Model Study for Sequence Pattern Extraction in Protein Function Prediction Problems

  • Lee, Jeung Min;Lee, Hyun
    • Journal of the Korea Society of Computer and Information
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    • v.27 no.8
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    • pp.49-59
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    • 2022
  • In this paper, we designed a new enzyme function prediction model PSCREM based on a study that compared and evaluated CNN and LSTM/GRU models, which are the most widely used deep learning models in the field of predicting functions and structures using protein sequences in 2020, under the same conditions. Sequence evolution information was used to preserve detailed patterns which would miss in CNN convolution, and the relationship information between amino acids with functional significance was extracted through overlapping RNNs. It was referenced to feature map production. The RNN family of algorithms used in small CNN-RNN models are LSTM algorithms and GRU algorithms, which are usually stacked two to three times over 100 units, but in this paper, small RNNs consisting of 10 and 20 units are overlapped. The model used the PSSM profile, which is transformed from protein sequence data. The experiment proved 86.4% the performance for the problem of predicting the main classes of enzyme number, and it was confirmed that the performance was 84.4% accurate up to the sub-sub classes of enzyme number. Thus, PSCREM better identifies unique patterns related to protein function through overlapped RNN, and Overlapped RNN is proposed as a novel methodology for protein function and structure prediction extraction.

Factors influencing the Sexual Identity Formation of Sexual Minorities (LGB) in Korea: A Qualitative Meta-Summary (국내 성소수자의 성정체성 형성에 영향을 미치는 요인에 관한 질적 메타요약)

  • Pyo, Sohwi;Lee, Seul Ah;Jang, Aekyung;Lee, Joonwoo;Lee, Eunbi;Yang, Eunjoo
    • Korean Journal of Culture and Social Issue
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    • v.28 no.2
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    • pp.241-272
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    • 2022
  • This purpose of this study was to use the meta-summary method to systematically integrate the findings of the heterogeneous qualitative research on the factors influencing the sexual identity formation process of lesbian, gay, and bisexual groups in Korea. The integrative investigation of the universal or unique factors affecting the identity formation of sexual minority is important to understand their internal experiences and support their psychological adaptation. Using a qualitative meta-summary, this study systematically identified and abbriviated the psychological and social factors that promote or impede the sexual identity acceptance and integration of LGB individuals. First, a total of 9 studies which were published in Korea up to 2021 were identified through the research database. The included studies were critically evaluated by using the Critical Appraisal Screening Programme tool. A total of 179 statements were extracted from the findings of each study and 34 abstracted statements were generated. The 34 abstracted statements were categorized into four groups, psychological factors that promote or impede sexual identity formation and social factors that promote or impede it. These four main categories and corresponding factors in each category were explained. The implications and limitations were also discussed.

A Comparative Research on End-to-End Clinical Entity and Relation Extraction using Deep Neural Networks: Pipeline vs. Joint Models (심층 신경망을 활용한 진료 기록 문헌에서의 종단형 개체명 및 관계 추출 비교 연구 - 파이프라인 모델과 결합 모델을 중심으로 -)

  • Sung-Pil Choi
    • Journal of the Korean Society for Library and Information Science
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    • v.57 no.1
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    • pp.93-114
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    • 2023
  • Information extraction can facilitate the intensive analysis of documents by providing semantic triples which consist of named entities and their relations recognized in the texts. However, most of the research so far has been carried out separately for named entity recognition and relation extraction as individual studies, and as a result, the effective performance evaluation of the entire information extraction systems was not performed properly. This paper introduces two models of end-to-end information extraction that can extract various entity names in clinical records and their relationships in the form of semantic triples, namely pipeline and joint models and compares their performances in depth. The pipeline model consists of an entity recognition sub-system based on bidirectional GRU-CRFs and a relation extraction module using multiple encoding scheme, whereas the joint model was implemented with a single bidirectional GRU-CRFs equipped with multi-head labeling method. In the experiments using i2b2/VA 2010, the performance of the pipeline model was 5.5% (F-measure) higher. In addition, through a comparative experiment with existing state-of-the-art systems using large-scale neural language models and manually constructed features, the objective performance level of the end-to-end models implemented in this paper could be identified properly.

The effect of external influence and operational management level on urban water system from water-energy nexus perspective (물-에너지 넥서스 관점에서 외부영향과 운영관리 수준이 도시물순환시스템에 미치는 영향)

  • Choi, Seo Hyung;Shin, Bongwoo;Song, Youngseok;Kim, Dongkyun;Shin, Eunher
    • Journal of Korea Water Resources Association
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    • v.56 no.9
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    • pp.587-602
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    • 2023
  • Due to climate change, population growth, and economic development, the demand for water in the urban water system (UWS) and the energy required for water use constantly increase. Therefore, beyond the traditional method of considering only the water sector, the Nexus approach, which considers synergies and trade-offs between the water and energy sectors, has begun to draw attention. In previous researches, the Nexus methodology was used to demonstrate that the UWS is an energy-intensive system, analyze the water-energy efficiency relationship surrogated by energy intensity, and identify climate (long-term climate change, drought, type), geographic characteristics (topography, flat ratio, location), system characteristics (total supply water amount, population density, pipeline length), and operational management level (water network pressure, leakage rate, water saving) effects on the UWS. Through this, it was possible to suggest the direction of policies and institutions to UWS managers. However, there was a limit to establishing and implementing specific action plans. This study built the energy intensity matrix of the UWS, quantified the impact of city conditions, external influences, and operational management levels on the UWS using the water-energy Nexus model, and introduced water-energy efficiency criteria. With this, UWS managers will be able to derive strategies and action plans for efficient operation management of the UWS and evaluate suitability and validity after implementation.

Gold Recovery from Cyanide Solution through Biosorption, Desorption and Incineration with Waste Biomass of Corynebacterium glutamicum as Biosorbent (생체흡착, 탈착 및 회화를 이용한 시안 용액으로부터 금의 회수)

  • Bae, Min-A;Kwak, In-Seob;Won, Sung-Wook;Yun, Yeoung-Sang
    • Clean Technology
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    • v.16 no.2
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    • pp.117-123
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    • 2010
  • In this study, we propose two methods able to recover different type of gold from gold-cyanide solutions: biosorption and desorption process for mono-valent gold recovery and biosorption and incineration process for zero-valent gold recovery. The waste bacterial biomass of Corynebacterium glutamicum generated from amino acid fermentation industry was used as a biosorbent. The pH edge experiments indicated that the optimal pH range was pH 2 - 3. From isothermal experiment and its fitting with Langmuir equation, the maximum uptake capacity of Au(I) at pH 2.5 were determined to be 35.15 mg/g. Kinetic tests evidenced that the process is very fast so that biosorption equilibrium was completed within the 60 min. To recover Au(I), the gold ions were able to be successfully eluted from the Au-loaded biosorbent by changing the pH to pH 7 and the desorption efficiency was 91%. This indicates that the combined process of biosorption and desorption would be effective for the recovery of Au(I). In order to recover zero-valent gold, the Au-loaded biosorbents were incinerated. The content of zero-valent gold in the incineration ash was as high as 85%. Therefore, we claim on the basis of the results that two suggested combined processes could be useful to recover gold from cyanide solutions and chosen according to the type of gold to be recovered.

A study on the Construction of a Big Data-based Urban Information and Public Transportation Accessibility Analysis Platforms- Focused on Gwangju Metropolitan City - (빅데이터 기반의 도시정보·접대중교통근성 분석 플랫폼 구축 방안에 관한 연구 -광주광역시를 중심으로-)

  • Sangkeun Lee;Seungmin Yu;Jun Lee;Daeill Kim
    • Smart Media Journal
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    • v.11 no.11
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    • pp.49-62
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    • 2022
  • Recently, with the development of Smart City Solutions such as Big data, AI, IoT, Autonomous driving, and Digital twins around the world, the proliferation of various smart devices and social media, and the record of the deeds that people have left everywhere, the construction of Smart Cities using the "Big Data" environment in which so much information and data is produced that it is impossible to gauge the scale is actively underway. The Purpose of this study is to construct an objective and systematic analysis Model based on Big Data to improve the transportation convenience of citizens and formulate efficient policies in Urban Information and Public Transportation accessibility in sustainable Smart Cities following the 4th Industrial Revolution. It is also to derive the methodology of developing a Big Data-Based public transport accessibility and policy management Platform using a sustainable Urban Public DB and a Private DB. To this end, Detailed Living Areas made a division and the accessibility of basic living amenities of Gwangju Metropolitan City, and the Public Transportation system based on Big Data were analyzed. As a result, it was Proposed to construct a Big Data-based Urban Information and Public Transportation accessibility Platform, such as 1) Using Big Data for public transportation network evaluation, 2) Supporting Transportation means/service decision-making based on Big Data, 3) Providing urban traffic network monitoring services, and 4) Analyzing parking demand sources and providing improvement measures.

Research trends in seabird and marine fish migration: Focusing on tracking methods and previous studies (바닷새 및 해양어류의 이동 연구 동향: 위치추적 기법과 연구 사례를 중심으로)

  • Jin-Hwan Choi;Seongho Yun;Mi-Jin Hong;Ki-Ho Kang;Who-Seung Lee
    • Korean Journal of Environmental Biology
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    • v.40 no.1
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    • pp.25-53
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    • 2022
  • In this study, trends in research methods and topics of seabird and marine fish migration were examined. Based on the framework of existing animal migration studies, future research directions were proposed in relation to the migration of seabirds and fish. In terms of research methodology, with the development of science and technology, tracking techniques using radio telemetry, acoustic telemetry, RFID (radio-frequency identification), satellite tracking, and geolocators are widely used to study seabird and fish migration. Research is also conducted indirectly through a population survey and the analysis of substances in the body. Research contents are largely classified into extrinsic factors that affect migration(such as environmental variables and interspecific competition), intrinsic factors such as hormones, anthropogenic activities including fishery and offshore wind farm, and the effect of global climate change. In future studies, physiological factors that influence or cause migration and dispersal should be identified concerning intrinsic factors. For the analysis of migration ability, it is necessary to study effects of changes in the magnetic field on the migration ability of seabirds and fish, interspecific differences in spatiotemporal migration ability, and factors that influence the migration success rate. Regarding extrinsic factors, research studies on effects of anthropogenic disturbances such as fishery and offshore wind farm and global climate change on the migration and dispersal patterns of marine animals are needed. Finally, integrated studies on the migration of seabirds and fish directly or indirectly affecting each other in various ecological aspects are required.

A Study on Risk Issues and Policy for Future Society of Digital Transformation: Focusing on Artificial Intelligence (디지털 전환의 미래사회 위험이슈 및 정책적 대응 방향: 인공지능을 중심으로)

  • Koo, Bonjin
    • Journal of Technology Innovation
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    • v.30 no.1
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    • pp.1-20
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    • 2022
  • Digital transformation refers to the economic and social effects of digitisation and digitalisation. Although digital transformation acts as a useful tool for economic/social development and enhancing the convenience of life, it can have negative effects (misuse of personal information, ethical problems, deepening social gaps, etc.). The government is actively establishing policies to promote digital transformation to secure competitiveness and technological hegemony, however, understanding of digital transformation-related risk issues and implementing policies to prevent them are relatively slow. Thus, this study systematically identifies risk issues of the future society that can be caused by digital transformation based on quantitative analysis of media articles big data through the Embedded Topic Modeling method. Specifically, first, detailed issues of negative effects of digital transformation in major countries were identified. Then detailed issues of negative effects of artificial intelligence in major countries and Korea were identified. Further, by synthesizing the results, future direction of the government's digital transformation policies for responding the negative effects was proposed. The policy implications are as follows. First, since the negative effects of digital transformation does not only affect technological fields but also affect the overall society, such as national security, social issues, and fairness issues. Therefore, the government should not only promote the positive functions of digital transformation, but also prepare policies to counter the negative functions of digital transformation. Second, the detailed issues of future social risks of digital transformation appear differently depending on contexts, so the government should establish a policy to respond to the negative effects of digital transformation in consideration of the national and social context. Third, the government should set a major direction for responding negative effects of digital transformation to minimize confusion among stakeholders, and prepare effective policy measures.

Natural, Nature-based Features (NNbF) - A Comparative Analysis with Nature-based Solutions (NbS) and Assessment of Its Applicability to Korea (자연/자연기반 특징(NNbF) - 자연기반해법(NbS)과 비교분석 및 국내적용성 평가)

  • Hyoseop Woo
    • Ecology and Resilient Infrastructure
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    • v.10 no.2
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    • pp.31-39
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    • 2023
  • NNbF is a newly emerging approach to reduce flood risk in coastal and fluvial areas using natural features or engineered nature-based features with the expectation of co-benefits of provisional, regulating, and socio-cultural services provided by the ecosystem. NNbF is not quite different from existing, related terms based on nature, such as NbS, Eco-DRR, NI, GI, EwN, and BwN, for all these terms include expectation of benefits for human societies by directly utilizing or mimicking nature's ecological functions. If we focus on the comprehensiveness of each term's subject and object, we can say that NbS > NNbF > (Eco-DRR, NI/GI). Among the 18 measures introduced in the NNbF International Guideline in the river and floodplain management category, it was found that measures of wash lands and floodplain restoration, including levee setback/removal and side-channel restoration, seemed to be the most applicable to rivers in Korea. These selected measures could be more effective when river managers purchase riparian lands along river courses by relevant laws for river water-quality protection.

A Study on customer experience centered innovation model for Funeral Mutual Enterprise - Centered on Funeral service - (상조기업의 고객경험 기반 혁신모델 연구 - 장례서비스 산업을 중심으로 -)

  • Ahn, Jinho;Lee, Jeungsun
    • Journal of Service Research and Studies
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    • v.11 no.2
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    • pp.67-77
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    • 2021
  • This study is a study on the methodology of establishing an innovation strategy centering on the customer experience, which is essential in order to transform the existing collection and preservation-centered mutual aid company service into a visitor-centered service. To this end, we conducted literature research on environmental changes in the funeral industry from the perspective of service science and the significance and value of customer experiences within them, good customer experiences and bad customer experiences from the perspective of customer experience management. A study was conducted to present and prove a specific model. The customer experience-oriented innovation strategy of the funeral industry means to search for various alternatives that can reach the target state from the present state, focusing on the customer, and select the most appropriate transformation plan among them. As an effect of application, it was found that it is a source of differentiation by generating positive emotions to customers, and that customer experience data is highly helpful in making important decisions for the actual resource input of the parent company. This innovation model was presented, and its value was firstly proved by analyzing the difference from the existing evaluation method. Finally, as a result of analyzing the causal relationship through regression analysis using the customer experience measurement procedure, customer experience diagnosis/evaluation, customer experience innovation strategy, and cooperative company's performance as variables, the relationship proved to be significant.