• Journal of Life Science
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• v.14 no.2
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• pp.275-279
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• 2004

Gene polymorphisms of cytokines and their receptors are attractive candidates as genetic factors in the pathogenesis of immune-mediated diseases and have been reported to be associated with disease susceptibility to autoimmune, inflammatory and infectious diseases. IL-29 is one of important candidate genes for complex trait of genetic diseases but there is no published survey of single nucleotide polymorphisms (SNPs) in this gene. In this study, for the first time, we have examined the full genomic sequence of IL-29 including the promoter regions to identify SNPs. We examined the frequencies of genotypes and alleles at the SNP site of IL-29 in allergic rhinitis patients and non-allergic rhinitis controls using the direct sequencing method to determine whether this IL-29 SNP is associated with allergic rhinitis in Korean population. We identified one novel SNP (1184C＞A) in the intron 2 and one novel variation site (-1842_-1841dupGA) in the promoter region of human IL-29 gene. The P values of SNP or variation site were not significant between the healthy controls and allergic rhinitis patients. Our results suggest that the 1184C＞A polymorphism and -1842_-1841dupGA variation site in human IL-29 gene were not associated to allergic rhinitis.

• The Journal of Korean Medicine
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• v.17 no.1 s.31
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• pp.407-432
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• 1996

Clinical Observation was made on 37 cases of Endotracheal intubation patients in the ICU of Oriental Medical Hosptal of Tae- Jon University from January in 1992 to June in 1995. 1. There were many cases of Endotracheal intubation in ischemic attack hemorragic in order. 2. Cerebral embolism mostly occured in the MCA territory and cerebral thrombosis, ICH, in the pons, generally. 3. On admission the consciousness of the most patients was 3 to 7 point by GCS. 4. The ordinary preceeding disease was hypertension. 5. Most patients were discharged from ICU after 2 days. 5. Most patients were discharged from ICU after 2 days. 6. Endotracheal intubation was done most frequently from 1 p.m. to 3 p.m. and intubated time was less than 2 hours. 7. Endotracheal intubation was done in case of heart arrest than dyspnea cases. 8. The main complication of patients of C.V.A. in ICU were urinary tract infection, pneumonia in order. 9. There were no side effects after and by Endotracheal intubation.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.35 no.1
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• pp.41-46
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• 2009

Problems with scalp lead to hair loss, dandruff, itchiness, and other illness. No clear causes of these problems have been found and it is difficult to treat them. Therefore, the best way to prevent and treat any problems with scalp is to maintain physiological homeostasis of scalp to keep it healthy. Recently, many scalp and hair product brands have attempted to use medicinal herbs which have been extracted in hot water and mixed with other ingredients due to mass-production and standardization issues. However, many nutrients and active substances are destroyed by hot-water extraction. Therefore, this study has applied low-temperature rendering to minimize destruction of substances to extract black beans, peony, and green tea that are known to improve conditions of scalp. Then, their contribution to the improvement of scalp health was assessed. In result, it was found that low-temperature rendering retains over two times greater anti-oxidizing strengths than hot-water extraction and that the extracts from low-temperature rendering effectively strengthen follicles and hair, moisturize scalp, and prevent itchiness. Therefore, low-temperature rendered black beans, peony, and green tea extracts can be used to make effective scalp treatments.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.5 no.1
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• pp.150-161
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• 1994

Clinical Characteristics of 83 tic patients referred to child psychiatric clinics were studied including the patients' sexes, birth orders and onset ages. We compared the differences between patients and normal control regarding the co-morbidity, and mothering attitude using CBCL(Child Behavioral Check List) and MBRI(Mothering Behavior Rating Instrument). And we also evaluated the influence of types of tic disorder and the presence of behavioral characteristics of the tic patients. The following results were obtained. 1) The sex ration was 5.9:1, male dominant. 2) The eldest children were being twice as many as the youngest children(eldest : youngest : single=4.7 : 1.7 : 1). 3) The eldest children tended to have earlier onset than others. 4) The tic children as a whole had more accompanying behavioral problems than the normal children according to the CBCL scales' scores. 5) The mothers of tic children had more negative view of their children, more rejecting and more hostile attitude toward their children. 6) The types of tic disorder(the Tourette disorder vs chronic moter tic disorder) did not make a difference in the incidence of behavior problems. 7) Those who had attentional problems regardless the types of tic had more behavioral problems than those who had not. 8) Those who had familial loadings of tic disorder tended to have more likely Tourette disorders than chronic tic disorders.

• Journal of Acupuncture Research
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• v.22 no.3
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• pp.243-252
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• 2005

Objective : This study was performed to investigate the effect of blood-letting cupping treatment for acute ankle sprain because there are few studies with evidence-based approach. Method : Twenty-nine patients, who had no fracture and had injured by external force and had less than 1 week passed since onset and had not been treated, were randomly divided into control or treatment group by tossing a coin. The treatment group received blood-letting cupping. After 3rd treatment, the outcomes were assessed using Ankle-Hindfoot Scale (AHS) and Numeric Rating Scale (NRS). Result : Nineteen out of 29 patients were finally assessed. The treatment group (n=11) was significantly different from the control group (n=8) in AHS and NRS (p=0.041, 0.026, respectively). Conclusion : The blood-letting cupping has an objective effect on reduing pain for acute ankle sprain.

• Proceedings of the KSCN Conference
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• 2003.11a
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• pp.1091-1092
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• 2003

당뇨병은 발병한 후에는 혈당조절을 위한 식사요법 실천이 평생에 걸쳐 지속적으로 이루어져야하는 질환이므로 식사요법에 대한 영양교육이 매우 중요하다. 본 연구에서는 지속적인 실습을 포함하는 소그룹 단위의 영양교육프로그램을 실시함으로써 식사요법 실천에 미치는 영향에 대해 알아보고자 하였다. 2003년 4월부터 7월까지 보건소에서 여성 당뇨병 환자 13명을 대상으로 혈당에 가장 영향을 미치는 당질식품의 적정섭취와 균형있고 규칙적인 식사를 강조한 쉬운 식사요법 교실의 형태로 연속 4주간, 2시간의 교육형태로 그룹인원을 5명 이하로 하여 실시하였다. 설문조사를 통하여 식사요법 장애 인자를 파악하였으며 교육 전후에 식사 섭취량, 혈당 허리둘레를 측정하여 비교하였다. 대상자의 평균 연령은 57.85 $\pm$ 9.55세, 유병 기간 6.38 $\pm$ 2.9년이었다 식사요법 교육을 받은 경험이 있는 환자는 15.4%이며 당뇨병 가족력을 가지고 있는 환자는 53.8%이었다. 당뇨병 발견 동기는 증상 .있었던 경우가 23.1%, 종합 진단시 발견된 경우 15.4%, 타 질환 치료시 알게된 경우 61.5%이었다. 저혈당 증세 및 대처방법을 알고 있는 환자는 53.8%이었다. 식사요법시 장애인자를 항목별로 질문하였을 때 가장 큰 장애는 주위에서 더 먹으라고 권유하는 것, 식사요법은 나에게 큰짐이 된다는 생각, 식사요법보다 일상생활에서 더 중요한 것이 많음이 53.8%로 답하였다. 교육 전후의 식사 섭취 량을 비교하였을 때 교육 전 에너지 섭취량은 1579.6 $\pm$ 355.8㎉ 교육 후 1505 $\pm$ 425.3㎉로서 70㎉정도 감소하였다. 교육 시 처방한 열량의 98.3%를 섭취하고 있었다. 당질섭취는 교육 전 257$\pm$60.6g 교육 후 214.8$\pm$56.1g로 감소하였고 단백질, 지질의 섭취는 교육전후에 큰 차이가 없었다. 총열량에 대한 3대 영양소의 섭취비율은 교육 전 57:23:20에서 교육 후 51:28:21로 당질비율은 감소하고 지질이나 단백질 섭취비율이 증가하였다. 교육전 후 식품군 별 섭취 량을 식품교환단위 수로 비교하였을 때 곡류군 섭취는 교육 전 5.87 $\pm$ 2.51에서 교육 후 5.38 $\pm$ 1.71로 교육후 당질 식품 섭취량이 감소하였으나 통계적으로 유의성은 나타나지 않았다. 교육 후 식품선택에서의 큰 변화는 과일류 중 토마토 섭취 비율 증가로 교육 전에는 총 과일 섭취량의 19.87%에서 교육 후에는 56.32%로 증가했다. 혈당은 교육후 42.8mg/㎗ 감소한 것으로 나타났으며 허리둘레는 교육 전 평균 83.8 $\pm$ 5.75에서 교육 후 82.33 $\pm$ 5.89cm로 약 1.5cm가량 감소하였다. 따라서 당질 식품 적정 섭취에 대한 실습 위주의 단기간 영양교육은 당뇨병 관리에 유익한 것으로 평가되었다.

• Weed & Turfgrass Science
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• v.5 no.1
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• pp.29-34
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• 2016

Large patch disease in Zoysia japonica Steud. is the most destructive disease in turfgrass. For large patch management, it has been dependent on chemical controls but pesticides are harmful to soil, water and biodiversity. In this study, we evaluated 4 Streptomyces spp. strains (S2, S5, S8 and S12) which were selected in previous studies using metagenome approaches. Root colonization of the strains, large patch suppressing effect and the pathogen density change in actual golf course were investigated to evaluate biological control potential of the strains. All strains exhibited reliable root colonization ability that strains populations were higher than $6log\;cfu\;g^{-1}$ in turfgrass rhizosphere. The pathogen density, with S8 treatment, was detected average of 0.7 after a week and average of 1.2 after 4 weeks. Disease control and suppressive the pathogen population by S8 strain showed higher efficiency than other strains. S8 was applied in an actual golf course for the large patch control and pathogen density. The pathogen density in S8 treatment plot was detected below 1.6 per toothpick and lower compared with untreated plot. The results indicated that pathogen density was suppressed by S8 and the stain has great potential as a biological control agent for the large patch.

• Journal of the Korean Data and Information Science Society
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• v.25 no.5
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• pp.1095-1106
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• 2014

Symbolic data analysis extends the data mining and exploratory data analysis to the knowledge mining, we can suggest the SDA tree model on clinical and genomic data with new knowledge mining SDA approach. Using SDA application for huge genomic SNP data, we can get the correlation the availability of understanding of hidden structure of HCC data could be proved. We can confirm validity of application of SDA to the tree structured progression model and to quantify the clinical lab data and SNP data for early diagnosis of HCC. Our proposed model constructs the representative model for HCC survival time and causal association with their SNP gene data. To fit the simple and easy interpretation tree structured survival model which could reduced from huge clinical and genomic data under the new statistical theory of knowledge mining with SDA.

• Korean Journal of Psychosomatic Medicine
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• v.6 no.1
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• pp.79-84
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• 1998

Authors report a case of poststroke bipolar disorder that occurs much less frequently than poststroke depression(PSD). A MRI study performed to identify the etiology of a secondary manic episode in a patient with preceded PSD after left basal ganglia infarction revealed newly developed right basal ganglia infarction associated with poststroke bipolar disorder. It is interesting to note that (1) the temporal relationship was found between the occurrence of PSD after left hemisphere stroke and the occurrence of poststroke bipolar disorder following right hemisphere stroke, and that (2) the occurrence of PSD and the occurrence of poststroke bipolar disorder are associated with lesion location respectively. It has been reported that bipolar disorders were associated with subcortical lesions of the right hemisphere, whereas right-cortical lesions led to unipolar mania and that risk factors for mania included a family history of psychiatric disorders and mild subcortical atrophy. In this case, MR image shows subcortical lesions of the right hemisphere and mild subcortical atrophy. The investigation of the relationships among stroke lesion locations and potstroke mood disorders and risk factors for poststroke bipolar disorder may contribute to understanding the neurobiology of primary mood disorder. A clinical implication is that the risk of secondary bipolar disorder after cerebral infarction should be highlighted.

• Parasites, Hosts and Diseases
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• v.32 no.3
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• pp.195-200
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• 1994

Malaria is estimated to have a worldwide incidence of more than 100 million clinical cases and approximately 1 miuion deaths per year. Korea, although previously tnlown as an endemic area of tertian malaria (Pzosmonin vivax), has been considered free from malaria as there had been no report on indigenous cases since 1984. Recently, however, we experienced an indigenous case of P. viuax infection in a young man who had never been abroad. The patient was a 23-year-old Korean soldier with 18-day history of recurrent fever and chill lasting 4 to 8 hours on alternative days since mid-July 1993. He had lived in Changwon, Hyongsangnam-do, before entering barracks located in Paiu-gun, Kyonggj-do on Jne 1992, and had never been out of Korea. He had no history of blood transfusion nor parenteral use of drugs. The peripheral blood smears showed typical ring forms, trophozoites, and gametocytes of p. uiuox, in addition to mild anemia and thrombocytopenia. After confirmation of the diagnosis, he was treated with hydroxychloroquine and primaquine. Follow-up blood smears no more revealed malaria parasites. It is not certain whether the present case is due to a resurgence of indigenous malaria or a secondary infection from introduced mnuia. Whichever the source of infection the domestic occurrence of mnuia cycle in Korea should be a warning sign in public health point of view.