• Korean Journal of Veterinary Research
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• v.37 no.3
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• pp.687-692
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• 1997

개의 전립선에서 경직장 초음파상에 나타나는 미만성 저에코영역의 성상과 경직장 초음파 검사법의 유용성을 알아보기 위해 히스토그람 분석방법과 color doppler 초음파를 이용하여 전립선 맛사지에 따른 전립선 실질의 에코변화를 비교하였다. 전립선 맛사지 후 히스토그람상의 휘도치는 전립선 요도부 기준 상부측 실질내에서 유의성(p<0.01) 있게 고에코로 변화되어 나타났으며, 전립선내에 분포하는 혈관은 저에코영역에서 보다 고에코영역에서 발견되었다. 이상의 결과로 보아 경직장 초음파 검사법은 전립선의 미세한 변화에 대해 보다 상세한 실질내의 정보를 제공할 수 있는 효과적인 검사 방법이며, 맛사지에 따른 휘도치의 변화는 전립선의 물리적 자극에 대한 전립선액의 분비에 따른 결과로 사료되고, 저에코영역은 혈관보다는 전립선액이 점유하고 있는 것으로 생각된다.

• Investigative Magnetic Resonance Imaging
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• v.16 no.1
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• pp.1-5
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• 2012

Breast MRI is the most accurate adjunctive to the mammography for the screening of breast cancer. Despite lack of randomized controlled trials on the effectiveness of MRI screening, it is now recommended for the women at high risk for breast cancer by the American Cancer Society and the National Comprehensive Cancer Network based on several prospective observational studies. In Korea, a retrospective study reported that preoperative MRI screening of the contralateral breast in women with unilateral breast cancer was associated with reduced metachronous cancer incidence. To introduce breast MRI as a supplemental modality to screening mammography in Korea, standardization and education of interpretation, establishment of MR-guided biopsy and adequate indication, and evaluation of cost-effectiveness and should be preceded.

• Clinical and Experimental Pediatrics
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• v.45 no.7
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• pp.862-874
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• 2002

Purpose : We tried to evaluate whether the detection rate of Helicobacter pylori in gastric biopsy specimens could be improved by using pre-embedding immunoelectron microscopy. Methods : A total of 119 children who complained of upper gastrointestinal symptoms were endoscoped at the Gyeongsang National University Hospital from July, 1996 to July, 1999. Five biopsy specimens(three for urease test, one for hematoxylin-eosin(H & E) staining, and one for preembedding immunoelectron microscopy) were obtained from each antrum and body. Immunoblotting analysis were also performed. Results : Among the 119 patients, H. pylori were found in 116 patients(97.5%) by the immunoelectron microscopy. Among three patients who were found H. pylori negative in immunoelectron microscopy, two patients showed H. pylori in H & E stained slides and one patient was urease test positive(color change within six hours). Urease tests were positive in 107 patients(89.9 %). The positive rate of immunoblotting tests was 81.5%. However, only 13 patients(10.9%) showed H. pylori on the H & E stained antrum or body tissue. Conclusion : In this study, we found H. pylori histopathologically in most of the pediatric patients who complained of upper gastrointestinal symptoms. This study showed that pre-embedding immunoelectron microscopic examinations can be used as a gold standard in the diagnosis of childhood H. pylori infection. However, this method also has limited capacity to detect widely scattered H. pylori compared to the other histopathologic diagnostic methods.

• RED RIBBON
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• s.68
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• pp.24-25
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• 2006

국내 첫 에이즈 감염인의 발견 2년 뒤인 1987년 국립보건원에 에이즈센터를 설립하면서 본격적으로 예방사업이 시작되었다. 같은 해에 후천성면역결핍증 예방법이 제정되었고, 모든 헌혈액에 대한 에이즈 검사와 특정집단에 대한 의무검사도 시작하게 되었다. 그뒤 1989년에는 각 지역 보건소에서 에이즈 무료의 명검사를 실시하게 되었다. 정부의 에이즈 예방과 확산금지에 대한 노력이 역부족이라는 판단 하에 대한에이즈예방협회와 한국에이즈퇴치연맹이 설립되면서 민간 차원에는 에이즈 예방 사업이 본격화되었다. 그 후 구세군과 대학적십자사에서도 에이즈 예방사업에 뛰어들었으며, 다양한 감염인 단체들이 생겼다 사라지곤 했다. 90년대 초부터 에이즈 사업에 뛰어든 역사와 내실을 자랑하는 단체들과 이제 막 형성된 신생단체까지 국내에서는 다양한 단체들이 에이즈 사업에 뛰어들고 있다.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.12
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• pp.678-685
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• 2016

Deglutition inspection has been the gold standard for inspection of dysphagia using a penetration device of the division of radiology to date. However, inspection using an endoscope has facilitated diagnosis of dysphagia in recent days. In this study, we compared the results of VFSS alone with those of VFSS combined with FEES to determine if the detection rate of penetration, aspiration, and pharyngeal residue increased. This study evaluated at 130 persons who underwent both VFSS and FEES from December 2013 through March 2014, and used VFSS (FELAVISION, SHIMADZU) and FESS (EVIU LUCERA CV-260SL, OLYMPUS) as devices. After preparing barium diluted solution, yogurt that diluted barium and rice that diluted barium in 2.5 ml, 5 ml, 10 ml by modifying Logemann's protocol in part, and having subjects take the solution, this study confirmed pharyngeal residue, penetration, aspiration etc. VFFS and FEES using full HD video revealed aspiration in 36 of the 130 patients in both inspections. Additionally, aspiration was discovered in 36 patients upon VFFS, but in 41 upon FESS. Although FEES was more sensitive at diagnosing dysphagia, the two inspection methods are complementary, so diagnostic value will be greatly improved when the endoscope operating method and accurate fluoroscopic inspection are combined.

• Proceedings of the Korea Water Resources Association Conference
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• 2019.05a
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• pp.104-104
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• 2019

기후 관측자료의 경우 관측, 가공, 전송 중에 오류가 발생할 수 있으며, 특히 글로벌 기후자료는 다양한 조건을 가지고 있는 자료를 수집하였기 때문에 일반적으로 해당 국가 관측자료보다 품질이 낮다. 본 연구에서는 글로벌 기후 관측자료의 품질을 개선할 수 있는 품질관리 기법을 개발하고 국내 지역에 적용해보고자 한다. 연구대상지역으로 국내 대표도시 7 곳을 선정하였으며, 글로벌 기후자료는 NCDC (National Climatic Data Center)의 일 단위 GSOD (Global Surface Summary of the Day) 자료를 수집하였다. 품질관리는 강수와 기온에 대해서 실시하였으며 과정은 크게 이상치 검사, 이상치 및 결측치 보정, 연, 월 단위 기후 자료 산정으로 구분된다. 이상치 검사는 중복성 검사, 내적일치성 검사, 기후범위 검사, 공간동질성 검사를 기반으로 구성되어 있다. 이상치 및 결측치 보정은 인접 관측소의 자료를 보간하여 수행하였으며, 보간기법은 4 방향 역거리 가중법을 활용하였다. 연, 월 단위 자료 산정은 자료의 결측률을 고려하여 일 단위 자료를 연, 월 단위 자료로 변환하는 과정이다. 이상치 검사 결과 대부분의 이상치는 기후범위와 공간동질성 검사에서 발견되는 것으로 나타났으며, 중복성 및 내적일치성 검사는 이상치 검출 효과가 적은 것으로 나타났다. 결측치 및 이상치 보간 결과 추정된 자료와 관측값 간의 상관관계가 있는 것으로 나타나 활용성이 있었다. 본 연구는 글로벌 자료의 품질관리 기법을 제시하였다는 점에서 활용성이 있으며, 향후 품질관리 기법의 검증에 관한 연구를 수행할 필요가 있다.

• Korean Journal of Biological Psychiatry
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• v.5 no.1
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• pp.3-16
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• 1998

The neurophysiological study has been widely used in search of the relationship between brain and behavior. The basic techniques for the animal experiments of this kind such as stereotaxic techniques, lesioning methods, the methods of electrical stimulation and recording, and confirmation of histological location were briefly reviewed. Nevertheless, the importance of complementary neurochemical, neuroanatomical and behavioral studies can not be neglected.

• Journal of the Korea Institute of Military Science and Technology
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• v.8 no.4 s.23
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• pp.77-84
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• 2005

In this research, usability testing techniques had been applied to currently operating Military Logistics System software, and the effects of improvements made were verified. Furthermore, this research aims to assist the army to execute their researches on usability testing in the future. Various usability testing techniques and guidelines presented in this paper will be easily adapted to the research environment of the army. Consequently, the results of this research would play an important role in future development and evaluation of the Military Logistics System software.

• Journal of Biomedical Engineering Research
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• v.18 no.4
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• pp.357-364
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• 1997

The early detection of breast cancer is clearly a key ingredient for reducing breast cancer mortality. Microcalcification is the only visible feature of the DCIS's(ductal carcinoma in situ) which consist 15 ~ 20% of screening-detected breast cancer. Therefore, the analysis of the shapes and distributions of microcalcifications is very significant for the early detection. The automatic detection procedures have b(:on the concern of digital image processing for many years. We proposed here one efficient method which is essentially statistical pattern classification accelerated by one representative feature, correlation coefficient. We compared the results by this additional feature with results by a simple gray level thresholding. The average detection rate was increased from 48% by gray level feature only to 83% by the proposed method The performances were evaluated with TP rates and FP counts, and also with Bayes errors.

• Clinical and Experimental Pediatrics
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• v.48 no.3
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• pp.292-297
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• 2005

Purpose : It is known that 3-50 percent of type 1 diabetes mellitus(T1DM) patients develop autoimmune thyroid disease. We analyzed the clinical characteristics of autoimmune thyroid disease(AITD) developed in patients with T1DM in Korean. Methods : The medical records of 139 patients, who were followed up in Department of Pediatrics, Seoul National University Children's Hospital from Jan. 1981 to Jul. 2004, were analyzed retrospectively. Results : Forty-four males and 95 females were enrolled. At least one of the autoantibodies for thyroid was positive in 54 cases. The detection rate for AITD was not correlated with sex ratio, control of T1DM, body mass index, age at diagnosis of T1DM, and familial history of thyroid disease, between two groups. In the male group, AITD was more frequently found at a younger age than in the female group. The frequency of AITD was significantly higher in the goiter group without sex differences. In the thyroid disease group, 40 patients(74.0 percent) were euthyroid, seven patients(12.9 percent) were hypothyroid, and seven patients(12.9 percent) were hyperthyroid. Conclusion : We should monitor thyroid function and autoantibodies routinely in T1DM patients who develop goiters, or young boys with T1DM.