• Korean Journal of Fisheries and Aquatic Sciences
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• v.26 no.4
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• pp.321-329
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• 1993

The present study was conducted to elucidate the body modulating function of fermented seafood products. Angiotensin converting enzyme (ACE) acts in blood pressure regulation, converting angiotensin I to the potent vasoconstrictor angiotensin II and inactivating the vasodilator bradykinin to raise blood pressure. Salted and fermented anchovy which is one of the traditional fermented seafood in Korea was tested for inhibitory activity against ACE. ACE inhibitory activity of salted anchovy during the period of fermentation was increased with the elapse of fermentation days until fermentation of 60 days, but thereafter decreased inversely. When the fermented product was extracted with $50\%$ ethanol, the ACE inhibitory activity was the highest. And the ACE inhibitory activity was proportion to the content of $50\%$ ethanol soluble peptide-nitrogen of the fermented product. From the profiles of gel permeation chromatography on a Bio-Gel P-2 of $50\%$ ethanol soluble fraction obtained from salted and fermented anchovy fermented for 60 days at an ambient temperature, the higher activity fractions were C'($IC_{50}=97{\mu}g\;protein/ml$) and D'($IC_{50}=65{\mu}g\;protein/ml$). Amino acid analysis showed that the large quantify of threonine, glutamic acid, lysine for C' and serine, proline for D', respectively.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.27 no.1
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• pp.1-6
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• 1994

Hydrolyzates which inhibit the angiotensin-I converting enzyme(ACE) were prepared from defatted anchovy meal by pepsin. These were tested for inhibitory activity against ACE, which is one of the hypertension inducing factors. The ACE inhibitory activity of the hydrolyzates increased until 20hrs of hydrolysis had elapsed but slightly decreased after that time. And presence of $50\%$ ethanol soluble peptide-nitrogen increased slowly up to 12hrs of hydrolysis, and then mainly increased until 20hrs of hydrolysis was completed. From the profiles of gel permeation chromatography on a Bio-gel P-2 of $50\%$ ethanol soluble fraction obtained from hydrolyzate for 20hrs, the higher active fractions were 2'($IC_{50}=45\;{\mu}g\;protein/ml$) and 4'($IC_{50}=76\;{\mu}g\;protein/ml$). Amino acid analysis showed major quantities of glutamic acid, leucine, lysine for 2'and aspartic acid, threonine for 4' respectively.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.9 no.3
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• pp.163-168
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• 1976

Three species of Rhodophyceae namely Chondrus ocellatus, Grateloupia filicina and Gigartina tenella were collected from the coast of Haeundae, Busan, on June 33, 1975. And analysed with respect to the content of carrageenan and such chemical characteristics as the content of sulphate and 3, 6-anhydrogalactose, the solubility in potassium chloride solution. In addition, the same chemical properties were tested on the fractions separated by the different concentration of potassium chloride. Carrageenan content in Chondrus ocellatus was relatively higher than two other samples. All the samples showed more than thirty five percent. The Gigartina-carrageenan showed the highest 3,6-anhydrogalactose content among three samples of carrageenan obtained from different species, and the lowest marked from the Grateloupia-carrageenan. In comparison of the solubility of carrageenan in potassium chloride solution, the precipitation yields at 0.125M potassium chloride were marked in order of Chondrus-carrageenan, Grateloupia-carrageenan, and Gigartina-carrageenan, and the yields at 0.125 M to 2.0 M potassium chloride were in Gigartina-carrageenan, Grateloupia-carrageenan, and Chondrus-carrageenan, and the yields from the soluble fraction at 2.0 M potassium chloride were in order of Grateloupia-carrageenan, Gigartina-carrageenan, and Chondrus-carrageenan. It is noteworthy from the result of characteristics of carrageenans that, 3,6-andydrogalactose content was closely related to the solubility of carrageenans in potassium chloride solution and to the sulphate content which might affect reversibly.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.16 no.2
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• pp.88-96
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• 1983

The effect of lowering water activity of various humectants has been reported in the previous papers. In this study, that effect of humectants used in combination with each other was discussed. Additionally, the Aw measurements were also compared to the predicted values of Aw derived from the equation of Raoult's law and the linear slope method by Sloan and Labuza. Each mixed humectant was thought to be salted-out by the other, and thus Aw values were observed to be somewhat lower as the result in all model preparations. The effect of lowering water activity by NaCl was the highest, and the efficiency of reduction of Aw was decreased in the order of NaCl, sodium lactate, glycerin, propylene glycol and sorbitol when each of them was combinated with other humectants. Aw values calculated by the equation of Raoult's law were not agreed so well to the measured Aw, so it was likely not to be the useful method for predicting Aw values in mixed humectants to far as they have showed higher ability for lowering Aw in the previous papers. The equations of prediction were derived from Aw values to be measured actually in the model Kamaboko.

• Journal of the Korean GEO-environmental Society
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• v.14 no.9
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• pp.5-12
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• 2013

In this study, each top-down load test and bi-directional load test has been performed on the 480mm diameter of two rock socketed drilled shafts, which are located next to each other, and the results have been compared. The result shows that the settlement from the equivalent load-settlement curve of bi-directional load test is smaller than one from top-down load test, because elastic is not considered in equivalent load-settlement curve of bi-directional load test. Therefore elastic shortening should be considered to obtain appropriate equivalent load-settlement curve. Three existing methods used to obtain equivalent load-settlement curve with consideration of elastic shortening has been compared with the result of top-down load test. The result shows that those existing methods are sufficiently applicable to the design. In addition, result of comparison between top-down load test and bi-directional load test shows that bi-directional load test was found to overestimate bearing capacity because it does not consider pile body failure.

• Journal of the Korean Society of Food Science and Nutrition
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• v.13 no.3
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• pp.263-267
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• 1984

The present study was conducted to elucidate the triglyceride composition of walnut oil. The triglycerides were separated by thin layer chromatography (TLC) and fractionated on the basis of partition numbers by reverse phase high performance liquid chromatography (HPLC) on a column packed with $\mu$-bondapak $C_{18}$ using methanol-chloroform mixture as a solvent system. Each of these collected fractions was fractionated again on the basis of acyl carbon number of triglyceride by gas liquid chromatography (GLC). The fatty acid composition of triglycerides for each partition numbered group was also analyzed by GLC. From the results, it was found that walnut oil consists of ten kinds of triglycerides, and the patterns of major ones in walnut oil were as follows: 53.3% of $(C_{18:2},\;C_{18:2},\;C_{18:2})$, 10.1% of $(C_{18:1},\;C_{18:2},\;C_{18:2})$, 5.4% of $(C_{18:1},\;C_{18:1},\;C_{18:2})$, 4.3% of $(C_{18:1},\;C_{18:2},\;C_{18:3})$, 3.9% of $(C_{18:0},\;C_{18:2},\;C_{18:2})$, 2.0% of $(C_{18:0},\;C_{18:1},\;C_{18:2})$, 1.8% of $(C_{18:0},\;C_{18:2},\;C_{18:2})$.

• Journal of the Korean Geotechnical Society
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• v.29 no.7
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• pp.17-36
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• 2013

In this paper, the empirical relations of skin friction and end bearing resistance with the results of site investigation in soft rock are proposed through the analysis of bi-directional pile load tests of rock socketed drilled shafts performed at large offshore bridge foundations and high-rise building projects (13 test piles in 4 projects). The site investigation and drilling for bi-directional pile load tests were performed at the centers of test piles, and f-w curves for skin friction and q-w curves for end bearing were plotted based on load-transfer measurements. From the above curves, the empirical relations of skin friction and end bearing resistance with the results of site investigation depending on the mobilized displacement are determined by multiple regression analysis and compared with previous studies. Since the f-w and q-w curves of rock-socketed piles in Korea show hardening behavior according to mobilized displacement, the developed empirical relations by the mobilized displacement are more reasonable than those of previous studies which could not consider the mobilized displacement and suggested the ultimate capacity with unconfined compressive strength only. Particularly, the developed equations correlated with unconfined compressive strength show the best correlations among the equations correlated with other parameters.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.37 no.1
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• pp.83-91
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• 2017

In case of estimation of settlement for the piled-raft foundation, it is necessary to consider interaction among raft, piles and soil. But, simple analytic methods usually are not applicable to considering this complicated interaction. In this study, a computer-based approximate analytic method, HDPR, was developed in consideration of above mentioned interaction in order to analysis of settlement for the piled-raft foundation. The finite element method was applied to raft analysis by means of the Mindlin plate theory, and soil and piles were modeled as springs which were connected with their raft. The linear spring which can consider multi layered soil and the non-linear spring were applied to soil springs and pile springs, respectively. The raft-piles-soil interaction was reflected to each spring. In order to verify the developed analytic method, it was compared and analyzed with 3D FEM analysis, existing approximate analytic method and site monitoring data. As a result, the developed analytic method showed reasonable results of settlement estimations of raft and piles for each case. From a practical point of view, it is confirmed that this analytic method is able to apply for analysis and design of the piled-raft foundation.

• Clinical and Experimental Reproductive Medicine
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• v.26 no.1
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• pp.111-116
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• 1999

Postpubertal mumps may result in ochitis and permanent testicular atrophy may develop following infection. This present study was initiated to evaluate the preventive effect of interferon-${\alpha}2B$ on infertilty after mumps orchitis. There were 21 patients with mumps orchitis between May 1990 and June 1997. Patients were randomly distributed into 2 groups: group 1 patients (n=13) maintained therapy with interferon-${\alpha}2B$ ($3{\times}10^6$ IU per day) and group 2 were managed by conservatively. All of the patients were evaluated with testis size measurement, mumps virus titer, hormone level, and if possible semen analysis. For group 1 patients symptoms disappeared within 2 to 3 days and the volume of testis returned to normal within 11 days and testis atrophy was not observed in all patients in follow up. But asthenospermia was continued in 4 patients (unilateral 2, bilateral 2). For group 2 patients symptoms disappeared within 5 to 6 days and the volume of testis returned to normal within 10 days and testis atrophy was observed in 3 patients (unilateral 2, bilateral 1) in floow up. Asthenospermia was continued in 4 patients (unilateral 2, bilateral 2). Sperm count and morphology were recovered all the recover in group 1, 4 patients had persistent reduced sperm count and morphology in group 2, respectively. These observations suggest that systemic interferon-${\alpha}2B$ treatment is highly effective in preventing infertilty as well as testicular atrophy after mumps orchitis.

• Tuberculosis and Respiratory Diseases
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• v.42 no.5
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• pp.737-743
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• 1995

Background: Pneumonia is a frequent complication in patients undergoing mechanical ventilation, Quantitative culture of protected specimen brush(PSB) have shown satisfactory diagnostic accuracy for the diagnosis of ventilator-associated pneumonia. However PSB method is invasive, expensive, and require a bronchoscopic procedure. But endotracheal aspiration(EA) is simple and less expensive. The purpose of our study was to investigate the diagnosic value of EA quantitative cultures. Method: We studied 15 cases of ventilator-associated pneumonia(for >72h of mechanical ventilation) patients. Patients were divided into two diagnostic categories. Group I was the patients who were suspicious of clinical pneumonia, Group II was the patients for control. The obtained samples by EA and PSB were homogenized for quantitative culture with a calibrated loop method in all patients. Result: Using $10^3cfu/ml$, $10^5cfu/ml$ as threshold in quantitative culture of PSB, EA respectively, we found that EA quantitative cultures represented a relatively sentive(70%) and relatively specific (60%) method to diagnose the ventilator-associated pneumonia. Conclusion: Although EA quantitative cultures are less specific than PSB for diagnosing ventilator-associated pneumonia. EA quantitative cultures correlated with PSB quantitative culture in patients with clinical pneumonia and may be used to treat these patients when bronchoscopic procedures are not available.