• Title/Summary/Keyword: 바이오 조직

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A histopathological study on porcine cysticercosis (돼지 유구낭미충증의 병리조직학적 관찰)

  • Shin, Tae-kyun;Kim, Seung-ho
    • Korean Journal of Veterinary Research
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    • v.33 no.3
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    • pp.465-469
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    • 1993
  • This paper dealt with the histopathological findings on the natural cysticercosis in pigs. Three cases of porcine cysticercosis, which had been kept in the Department of Veterinary Medicine, Cheju. University more than ten years, were histopathologically examined in order to see the host reaction to the parasite. Capsules containing scolex were mainly found in the fascia of skeletal muscle, heart, and brains. Microscopically, cysticerci in the epicardium and the fascia of skeletal muscles were encapsulated with fibroblasts and collagen fibers. Around capsules, there was infiltration of eosinophils, lymphocytes and macrophages, although the degree and severity of inflammatory reaction varied case by case. Cerebral cortex also had the inflammatory exudate of lymphoid cells in the vicinity of the scolex. whereas perivascular lymphocytic cuffings were commonly seen around capsules. GFAP immunoreactive fibers formed a limiting membrane along the outer side of capsules. There was also proliferation of GFAP-positive astrocytes encirling infiltrating lymphocytes around vessels. In the central nervous system, astrocytes and lympoid cells play an important role in the demarcation of cysts and local immunity, respectively. In conclusion, host tissue reaction in porcine cysticercosis seemed to vary significantly according to the affected organs of pigs. It is assumed that capsules containing worms seemed to be formed at early stage of cysticercosis.

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Interstitial Radium Implantation and Cobalt-60 Irradiation of the Tongue Cancer (IbidI) (설암의 조직간내 라디움치료에 관하여)

  • 안경성;박주방;윤용규
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1972.03a
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    • pp.16.1-16
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    • 1972
  • In 1971 there were 5 cases of the tongue cancer in stage I & II treated concomitantly with interstitial radium implantation and Cobalt-60 irradiation at the Yonsei University Hospital Cancer Center. This is the interim report of the course of the primary site of those treated cases.

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Effects of Storage Temperatures and Periods on the Direct Somatic Embryogenesis in Rehmannia glutinosa Liboschitz and Scrophularia buergeriana Miquel (지황과 현삼에서 배양전 저장 온도와 기간이 직접 체세포배 형성에 미치는 영향)

  • Park, Ju-Hyun;Song, Ji-Sook;Ohk, Hyun-Choong;Lim, Wan-Sang;Chae, Young-Am
    • Korean Journal of Medicinal Crop Science
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    • v.7 no.1
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    • pp.7-10
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    • 1999
  • The effects of storage temperature and periods as pretreatments on direct somatic embryogenesis or shoot development in liquid culture of leaves, stems and petioles of Rehmannia glutinosa and Scrophularia buergeriana were investigated. Proper storage Temperature for Rehmannia glutinosa was $8^{\circ}C$ and the leaf stock could be stored up to 12 weeks. In Scrophularia buergerjana. shoots were developed from the 20 week-stored petiole and stem at $8^{\circ}C$. In general, $8^{\circ}C$ was considered the most effective storage temperature in terms of storage cost.

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Nodular Fasciitis of the Thigh Mimicking Soft Tissue Sarcoma - Two Cases Report - (연부조직 육종으로 오인된 대퇴부의 결절성 근막염 - 2예 보고 -)

  • Jeon, Ho-Seung;Jeon, Seung-Ju;Kang, Yu-Mi;Moon, Chan-Sam;Ha, Seung-Joo
    • The Journal of the Korean bone and joint tumor society
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    • v.13 no.2
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    • pp.135-141
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    • 2007
  • Nodular faciitis is generally considered to be benign proliferation of fibroblasts and myoblasts, and it measures dimension up to 3cm. The characteristics such as rapid growth, abundant cellularity, and mitotic activity occasionally cause these lesions to mimic sarcoma. The authors experienced two cases of nodular fasciitis of the thigh, which were unusually large with dimension of more than 5cm. All of these two cases mimicked sarcoma and one of two cases, which initially mimicked sarcoma clinically and histologically in our hospital, was finally diagnosed as nodular fasciitis after requesting external consultation to several experienced pathologists. All of two cases had no evidence of recurrence at 2 years postoperatively. The lesions of unusually large dimension such as in our cases must be included in the differential diagnosis of soft tissue sarcoma. So we report two cases of nodular fasciitis of the thigh with a review of the current literature.

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A Study on the Effects of Internal Marketing Factors to Job Satisfaction, Emotional Labor, and Organizational Commitment of the Elderly Care Facility Employee (노인요양시설 종사자들의 내부마케팅 요인이 직무만족, 감정노동 및 조직몰입에 미치는 영향에 관한 연구)

  • Lee, Jae-Sun;Lee, Seung-Hee
    • Journal of Digital Convergence
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    • v.15 no.4
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    • pp.251-258
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    • 2017
  • The purpose of this study is to analyze the effects of internal marketing factors on organizational commitment and emotional labor in the elderly Care Worker. The data are collected through structured questionnaires. The Subjects of the final analysis is 191 persons working in the elderly care facilities in Gyeongnam and Gyeongbuk provinces. Hypothesis testing of the research model is performed using AMOS 18.0. The main results of this study are as follows. Internal marketing factors influenced only internal communication and management support for job satisfaction, internal support for managerial support for emotional labor, internal communication and management support for organizational commitment. The results of this study suggest that in order to enhance the organizational commitment of long-term care workers, it is important not to strengthen internal marketing capacity but to increase job performance first, and secondly, to improve job performance, It is necessary to establish a more diversified research on the variables of service quality of job satisfaction and emotional labor.

The Biosensor for L-Glutamine Using Tissue Slices of Wistar Rat (Wistar 쥐 조직을 이용한 L-Glutamine 바이오센서)

  • Bae, Jin Hyeon;Choe, Seong Mun;Im, Dong Jun;Kim, Wi Rak
    • Journal of the Korean Chemical Society
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    • v.38 no.3
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    • pp.200-207
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    • 1994
  • A biosensor for the measurement of L-glutamine has been constructed by immobilizing the slice of Wistar rat kidney and it's organelle on $NH_3$ gas-sensing electrode. The effects of pH, buffer solution, temperature and thickness of slice were investigated in order to optimize electrode response. The tissue sensor had the linearity in the range of L-glutamine concentration $8.0{\times}10^{-5}{\sim}1.0{\times}10^{-2} M$ with a slope of 53.8 mV/decade in 0.05 M phosphate buffer solution, pH 7.8 at $30^{\circ}C$, and optimum thickness of slice and response time were 30 ${\mu}m$ and 3∼5 min, respectively. The organelle sensor showed the linearity within L-glutamine concentration range of $1.2{\times}10^{-4}{\sim}5.0{\times}10^{-3} M$ with a slope of 54.0 mV/decade in 0.05 M phosphate buffer solution, pH 7.8 at $30^{\circ}C$, and response time was 6∼7 min, respectively. Thus, it is clear that the tissue and organelle sensor will be useful for L-glutamine measurements.

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Current and Future Perspectives of Lung Organoid and Lung-on-chip in Biomedical and Pharmaceutical Applications

  • Junhyoung Lee;Jimin Park;Sanghun Kim;Esther Han;Sungho Maeng;Jiyou Han
    • Journal of Life Science
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    • v.34 no.5
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    • pp.339-355
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    • 2024
  • The pulmonary system is a highly complex system that can only be understood by integrating its functional and structural aspects. Hence, in vivo animal models are generally used for pathological studies of pulmonary diseases and the evaluation of inhalation toxicity. However, to reduce the number of animals used in experimentation and with the consideration of animal welfare, alternative methods have been extensively developed. Notably, the Organization for Economic Co-operation and Development (OECD) and the United States Environmental Protection Agency (USEPA) have agreed to prohibit animal testing after 2030. Therefore, the latest advances in biotechnology are revolutionizing the approach to developing in vitro inhalation models. For example, lung organ-on-a-chip (OoC) and organoid models have been intensively studied alongside advancements in three-dimensional (3D) bioprinting and microfluidic systems. These modeling systems can more precisely imitate the complex biological environment compared to traditional in vivo animal experiments. This review paper addresses multiple aspects of the recent in vitro modeling systems of lung OoC and organoids. It includes discussions on the use of endothelial cells, epithelial cells, and fibroblasts composed of lung alveoli generated from pluripotent stem cells or cancer cells. Moreover, it covers lung air-liquid interface (ALI) systems, transwell membrane materials, and in silico models using artificial intelligence (AI) for the establishment and evaluation of in vitro pulmonary systems.

Changes of Physicochemical and Sensory Characteristics of Korean Pickled Cucumber with Different Preparation Methods (담금 방법을 달리한 오이지의 숙성 중 특성 변화)

  • 박미원;박용곤;장명숙
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.23 no.4
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    • pp.634-640
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    • 1994
  • This study was investigate to see the effects of preparation methods on the physicochemical and sensory characteristics of cucumber preserved with salt. The preparation methods were brining the cucumbers in 10 % NaCl solution (boiled, method A), 205 NaCl solution (boiled, method B) an d20 % NaCl solution (cool to $25^{\circ}C$ after boiling, method C). The cucumber preserved with boiled solution and high salt concentration showed slow fermentation rate. The rate of salt penetration during brining of cucumber preserved with salt increased. The green value of cucumber preserved with salt by method B was lower than by method A and C. The cutting force of cucumber preserved with walt measured by texture analyzer showed a rapid increasing rate during initial brining periods. As a result of the sensory evaluation for cucumber preserved with salt, there were significant differences in most of characteristics between the samples at 5% level. The cucumber preserved with salt in boiled 10% NaCl solution (method A) showed the highest scores in most of the characteristics.

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The Causal Relationship between Supervisor Transformational Leadership and Employee Self-leadership Affected by Organizational Support - with a Focus on the Security Organization at the Korean National Assembly - (국회 경호.경비조직의 지원에 따른 상사의 변혁적 리더십과 셀프리더십의 인과관계)

  • Lee, Ju-Lak
    • Korean Security Journal
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    • no.35
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    • pp.37-62
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    • 2013
  • One of the organizational characteristics in the modern society is the emphasis placed upon individual autonomy in an effort to promote and develop each member's morale as well as the efficiency in personnel management. Therefore, it can be understood that the importance of "Self" is recognized in work places and the leadership of supervisors and each member's self-management and control are also emphasized, leading to establishment of the "Self-leadership" concept. In this study, the effect of the Transformational Leadership of the supervisors on the subordinates' Self-leadership was analyzed and the causal factor of organizational support in the relationship between Transformational Leadership and Self-leadership was defined. A survey was conducted with 182 security officials at the National Assembly and the following results were obtained. First, Transformational Leadership had a positive effect on Self-leadership and the Transformational Leadership of the supervisors had a statistically significant impact on the organizational support awareness. Furthermore, organizational support showed a statistically significant mediator effect in the relationship between the Transformational Leadership of the supervisors and the Self-leadership of the subordinates. Finally, future directions in regard to the personnel management system were suggested.

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Formation of the $2^{nd}$ Phases in Spray Cast Al-25Si-(Fe,V) Alloy (분무주조 A1-25Si-(Fe,V) 합금에서의 2 차상 형성거동)

  • 박우진;이언식;안상호
    • Proceedings of the Korean Powder Metallurgy Institute Conference
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    • 2000.04a
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    • pp.16-16
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    • 2000
  • 분무주조법으로 제조된 Al-25Si-(Fe,V) 합금빌렛의 미세조직을 광학현미경, 주사전자현미경, 투과전자현미경으로 분석하였으며, 빌렛내에서 관찰되는 2차상의 형성거동을 정확히 분석하기 위해 over-sprayed 분말의 미세조직을 분무주조 빌렛과 함께 관찰하였다. 먼저 분무주조 빌렛을 표면으로부터 중심부까지 관찰한 결과, 분무주조 빌렛의 미세조직은 표면부 10mm 가량을 제외하고는 매우 균일한 미세조직을 보여주었다. 이에 본 연구에서는 분무주조 빌렛의 표면부와 중심부, 그리고 over-sprayed 분말조직으로 구분하여 각각에서 관찰되는 2차상을 관찰하였으며, 이를 바탕으로 분무주조 빌렛내에 형성된 2차상의 형성기구를 규명하고자 하였다. Over-sprayed 분말의 미세조직은 기지조직내에 균일하게 분포된 침상의 $\delta$-AlFeSi 상과 각형의 Si 입자로 구성되어 있었다. 반면, 분무주조 빌렛의 경우, 그 중심부에서는 기자조직내에 균일하게 분포된 막대형의 $\beta$-AlFeSi과 부정형의 조대한 Si입자가 관찰되었으며, 표면부에서는 부정형의 Si 입자와 함께 막대형의 $\beta$-AlFeSi/$\delta$-AlFeSi 복합상이 관찰되었다. 특히, 빌렛 표면부의 $\beta$-AlFeSi 상과 $\delta$-AlFeSi 상간에는 일정한 방위관계가 존재하였으며, 이러한 결과는 분무주조 빌렛내에 분포된 $\beta$-AlFeSi상들이 분무액적내에 형성된 준안정 $\delta$-AlFeSi 상으로부터 상분해되어 형성되었음을 제시한다. 이상의 분무주조 조직과 over-sprayed 분말의 미세조직으로부터 분무주조 빌렛의 최종 주조조직은 반응고상태의 분무액적 조직에 의해 지배됨을 알 수 있다.r plate)의 단면 미세조직 사진으로써 모재부와 오버레이충을 함께 보여주고 있다. 모재와 오버레이 충간의 경계면은 모재 일부가 용융된 후 웅고하면서 형성됨으로 인해서 도금이나 용사층과는 달리 매우 견고하게 결합되어 있다. 따라서 계면부의 탈락이라는 문 제점은 거의 없어 심한 응력을 받는 기계구조물 및 부품에도 본 기술은 널리 적용되고 있다. 그리고 사진 1에서 알 수 있는 바와 같이 모재와는 전혀 상이한 재료를 자유로이 선택하여 표면 유효층 일부만 오버레이시키며I 주조 및 단조가 불가능한 재료까지도 표면부에 오버레이 시킴으로 서 부품 및 설비의 제조에 있어 재료비의 절감과 제품의 수명이 획기적으로 개선될 수 있다. 그리고 최근에는 도금 빛 용사 둥과 같은 표면처리를 할 경우임의 소재 표면에 도금 및 용 사에 용이한 재료를 오버레이용접시킨 후 표면처리를 함으로써 보다 고품질의 표면층을 얻기위한 시도가 이루어지고 있다. 따라서 국내, 외의 오버레이 용접기술의 적용현황 및 대표적인 적용사례, 오버레이 용접기술 및 용접재료의 개발현황 둥을 중심으로 살펴봄으로서 아직 국내에서는 널리 알려지지 않은 본 기 술의 활용을 넓이고자 한다. within minimum time from beginning of the shutdown.및 12.36%, $101{\sim}200$일의 경우 12.78% 및 12.44%, 201일 이상의 경우 13.17% 및 11.30%로 201일 이상의 유기의 경우에만 대조구와 삭제 구간에 유의적인(p<0.05) 차이를 나타내었다.는 담수(淡水)에서 10%o의 해수(海水)로 이주된지 14일(日) 이후에 신장(腎臟)에서 수축된 것으로 나타났다. 30%o의 해수(海水)에 적응(適應)된 틸라피아의 평균 신사구체(腎絲球體)의 면적은 담수(淡水)에 적응된 개체의 면적보다 유의성있게 나타났다. 해수(海水)에 적응(適應)된 틸라피아의 신단위(腎單位)의 사

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