• Title/Summary/Keyword: 미세유체장치

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Oxygen Transfer and Hydraulic Characteristics in Bubble Column Bioreactor Applied Fine Bubble Air Diffusing System (미세기포 산기장치를 적용한 타워형 생물반응기의 산소전달 및 수력학적 특성)

  • Lee, Seung-Jin;Ko, Kyeong-Han;Ko, Myeong-Han;Yang, Jae-Kyeong;Kim, Yong-Guk
    • Journal of Korean Society of Environmental Engineers
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    • v.34 no.11
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    • pp.772-779
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    • 2012
  • For improving performance of conical air diffuser generating fine bubble, both experimental and numerical simulation method were used. After adapting diffusers inner real scale bubble column, suitable for various diffuser submergence, the effect of diffuser submergence on oxygen transfer performance such as Oxygen Transfer Coefficient ($K_{L}a_{20}$) and Standard Oxygen Transfer Efficiency (SOTE) was investigated empirically. As flow patterns for various diffuser number and submergence were revealed throughout hydrodynamic simulation for 2-phase fluid flow of air-water, the cause of the change for oxygen transfer performance was cleared up. As results of experimental performance, $K_{L}a_{20}$ was increased slightly by 7% and SOTE was increased drastically by 39~72%, 5.6% per meter. As results of numerical analysis, air volume fraction, air and water velocity in bioreactor were increased with analogous flow tendency by increasing diffuser number. As diffuser submergence increased, air volume fraction, air and water velocity were decreased slightly. Because circulative co-flow is determinant factor for bubble diffusion and rising velocity, excessive circulation intensity can result to worsen oxygen transfer by shortening bubble retention time and amount.

Investigation of Fracture Propagation in Cement by Hydraulic Fracturing Under the Tri-axial Stress Condition (시멘트 시료에 대한 삼축압축 환경에서의 수압파쇄시험 연구)

  • Riu, Hee-Sung;Jang, Hyun-Sic;Jang, Bo-An
    • The Journal of Engineering Geology
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    • v.27 no.3
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    • pp.233-244
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    • 2017
  • We conducted hydraulic fracturing experiments on cement samples to investigate the dependency of fracture propagation on the viscosity of injection fluid and the in situ stress state. Ten cubic samples (20 cm side length) were produced using cement that was cured in water for more than one month. Samples were placed in a tri-axial compression apparatus with three independent principal stresses. An injection hole was drilled and the sample was hydraulically fractured under a constant injection rate. We measured injection pressures and acoustic emissions (AE) during the experiments, and investigated the fracture patterns produced by hydraulic fracturing. Breakdown pressures increased exponentially with increasing viscosity of the injection fluid. Fracture patterns were dependent on differential stress (i.e., the difference between the major and minor principal stresses). At low differential stress, multiple fractures oriented sub-parallel to the major principal stress axis propagated from the injection hole, and in some samples the fracture orientation changed during propagation. However, at high differential stress, a single fracture propagated parallel to the major principal stress axis. AE results show similar patterns. At low differential stress, AE source locations were more widespread than at high differential stress, consistent with the fracture pattern results. Our study suggests that hydraulic fracturing during shale gas extraction should be performed parallel to the orientation of minimum differential stress.

Feasibility of Bladder Compression Molded Prepreg as Small Wind Turbine Blade Material (소형 풍력 터빈 블레이드 재료로서 블래더 가압 방식 몰드 성형 프리프레그의 타당성)

  • Yi, Bo-Gun;Seo, Seong-Won;Song, Myung-Ho
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.33 no.2
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    • pp.95-101
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    • 2020
  • The wind turbine blades should be designed to possess a high stiffness and should be fabricated with a light and high strength material because they serve under extreme combination of lift and drag forces, converting kinetic energy of wind into shaft work. The goal of this study is to understand the basic knowledge required to curtail the process time consumed during the construction of small wind turbine blades using carbon fiber reinforced polymer (CFRP) prepeg composites. The configuration of turbine rotor was determined using the QBlade freeware program. The fluid dynamics module simulated the loads exerted by the wind of a specific speed, and the stress analysis module predicted the distributions of equivalent von Mises stress for representing the blade structures. It was suggested to modify the shape of test specimen from ASTM D638 to decrease the variance in measured tensile strengths. Then, a series of experiments were performed to confirm that the bladder compression molded CFRP prepreg can provide sufficient strength to small wind turbine blades and decrease the cure time simultaneously.

REAL-TIME MEASUREMENT OF DENTINAL TUBULAR FLUID FLOW DURING AND AFTER AMALGAM AND COMPOSITE RESTORATIONS (아말감과 복합레진의 수복 과정과 수복 후 발생하는 상아세관액 흐름의 실시간 측정)

  • Kim, Sun-Young;Cho, Byeong-Hoon;Baek, Seung-Ho;Lim, Bum-Sun;Lee, In-Bog
    • Restorative Dentistry and Endodontics
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    • v.34 no.6
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    • pp.467-476
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    • 2009
  • The aim of this study was to measure the dentinal tubular fluid flow (DFF) during and after amalgam and composite restorations. A newly designed fluid flow measurement instrument was made. A third molar cut at 3 mm apical from the CEJ was connected to the flow measuring device under a hydrostatic pressure of 15 $cmH_2O$. Class I cavity was prepared and restored with either amalgam (Copalite varnish and Bestaloy) or composite (Z-250 with ScotchBond MultiPurpose: MP, Single Bond 2: SB, Clearfil SE Bond: CE and Easy Bond: EB as bonding systems). The DFF was measured from the intact tooth state through restoration procedures to 30 minutes after restoration, and re-measured at 3 and 7days after restoration. Inward fluid flow (IF) during cavity preparation was followed by outward flow (OF) after preparation, In amalgam restoration, the OF changed to IF during amalgam filling and slight OF followed after finishing. In composite restoration, application CE and EB showed a continuous OF and air-dry increased rapidly the OF until light-curing, whereas in MP and SB, rinse and dry caused IF and OF, respectively. Application of hydrophobic bonding resin in MP and CE caused a decrease in flow rate or even slight IF. Light-curing of adhesive and composite showed an abrupt IF. There was no statistically significant difference in the reduction of DFF among the materials at 30 min. 3 and 7 days after restoration (p > 0.05).

Convolution Neural Network for Prediction of DNA Length and Number of Species (DNA 길이와 혼합 종 개수 예측을 위한 합성곱 신경망)

  • Sunghee Yang;Yeone Kim;Hyomin Lee
    • Korean Chemical Engineering Research
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    • v.62 no.3
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    • pp.274-280
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    • 2024
  • Machine learning techniques utilizing neural networks have been employed in various fields such as disease gene discovery and diagnosis, drug development, and prediction of drug-induced liver injury. Disease features can be investigated by molecular information of DNA. In this study, we developed a neural network to predict the length of DNA and the number of DNA species in mixture solution which are representative molecular information of DNA. In order to address the time-consuming limitations of gel electrophoresis as conventional analysis, we analyzed the dynamic data of a microfluidic concentrating device. The dynamic data were reconstructed into a spatiotemporal map, which reduced the computational cost required for training and prediction. We employed a convolutional neural network to enhance the accuracy to analyze the spatiotemporal map. As a result, we successfully performed single DNA length prediction as single-variable regression, simultaneous prediction of multiple DNA lengths as multivariable regression, and prediction of the number of DNA species in mixture as binary classification. Additionally, based on the composition of training data, we proposed a solution to resolve the problem of prediction bias. By utilizing this study, it would be effectively performed that medical diagnosis using optical measurement such as liquid biopsy of cell-free DNA, cancer diagnosis, etc.

Characteristics of Micro-Particle Separation according to HRT Changes (HRT 변화에 따른 미세입자 분리 특성)

  • Ahn, Kwangho;Ahn, Jaehwan;Kim, I-Tae;Kim, Seoggu;Kang, Sungwon;Park, Eunzoo;Lee, Youngsup
    • Journal of Korean Society of Environmental Engineers
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    • v.35 no.12
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    • pp.937-942
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    • 2013
  • Fluid generated within the sonic or ultrasonic waves are reflected by the wall, while the opposite direction forming a predetermined sound wave to the acoustic standing wave is referred to. In this study, the frequency of 1.0 MHz and 2.0 MHz acoustic standing wave generation module is installed in a continuous particle separation device, the laminar flow of influent, taking into account the hydraulic retention time (HRT) in accordance with changes in particle separation characteristics investigated. Operation of a standing wave in the particle separation device about $1.3{\sim}2.8^{\circ}C$ temperature is increased, but did not significantly affect the formation of standing waves. During operation, the HRT 1 hr frequency 1.0 MHz 2 hr, 4 hr longer as the particle separation efficiency (turbidity) were 64.1%, 70.0%, 74.3% and, 2.0 MHz has 58.0%, respectively, depending on HRT, 61.8%, 70.7% in the respectively. That is, the same frequency, the HRT treatment efficiency is 10% or more, depending on differences in generation and, 1.0 MHz frequency, 2 hr, 2.0 MHz 4 hr at about 70% or more of the processing efficiency can be maintained. Frequency of 1.0 MHz and 2.0 MHz operation at the same time, as a result, HRT 1 hr, 2 hr, 4 hr particle separation efficiency of 63.8%, respectively, 70.6%, 77.6%, rather than the generation of standing waves appear continuous HRT is affecting a lot of particles to separate could know.