• Title/Summary/Keyword: 미세결합

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EFFECT OF SURFACE TREATMENTS OF FIBER POSTS ON BOND STRENGTH TO COMPOSITE RESIN CORES (섬유포스트의 표면 처리방법이 복합레진 코어와의 결합력에 미치는 영향)

  • Keum, Hye-Jo;Yoo, Hyun-Mi
    • Restorative Dentistry and Endodontics
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    • v.35 no.3
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    • pp.173-179
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    • 2010
  • The purpose of the present study was to compare the influence of post-surface treatment with silane, hydrogen peroxide, hydrofluoric acid or sandblasting and to investigate the effect of silane in combination of the other treatments on the microtensile bond strength between fiber posts and composite resins for core build-up. Thirty-two glass-fiber posts (FRC Postec Plus, Ivoclar Vivadent, Schaan, Liechtenstein) were divided into eight groups according to the different surface pretreatments performed: silane application (S); immersion in 28% hydrogen peroxide (HP); immersion in hydrogen peroxide followed by application of silane (HP-S); immersion in 4% hydrofluoric acid gel (HF); immersion in hydrofluoric acid gel followed by application of silane (HF-S); sandblasting with aluminum oxide particles (SB); sandblasting followed by application of silane (SB-S). In control group, no surface treatment was performed. The composite resin (Tetric Flow, Ivoclar Vivadent, Schaan, Liechtenstein) was applied onto the posts to produce the composite cylinder specimen. It was sectioned into sticks to measure the microtensile bond strength. The data was analyzed with one-way ANOVA and LSD test for post hoc comparison (p < 0.05). Post pretreatment with sandblasting enhanced the interfacial strength between the fiber posts and core materials. Moreover, sandblasting followed by application of silane appears to be the most effective method that can improve the clinical performance of glass fiber posts.

Machine learning-based Fine Dust Prediction Model using Meteorological data and Fine Dust data (기상 데이터와 미세먼지 데이터를 활용한 머신러닝 기반 미세먼지 예측 모형)

  • KIM, Hye-Lim;MOON, Tae-Heon
    • Journal of the Korean Association of Geographic Information Studies
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    • v.24 no.1
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    • pp.92-111
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    • 2021
  • As fine dust negatively affects disease, industry and economy, the people are sensitive to fine dust. Therefore, if the occurrence of fine dust can be predicted, countermeasures can be prepared in advance, which can be helpful for life and economy. Fine dust is affected by the weather and the degree of concentration of fine dust emission sources. The industrial sector has the largest amount of fine dust emissions, and in industrial complexes, factories emit a lot of fine dust as fine dust emission sources. This study targets regions with old industrial complexes in local cities. The purpose of this study is to explore the factors that cause fine dust and develop a predictive model that can predict the occurrence of fine dust. weather data and fine dust data were used, and variables that influence the generation of fine dust were extracted through multiple regression analysis. Based on the results of multiple regression analysis, a model with high predictive power was extracted by learning with a machine learning regression learner model. The performance of the model was confirmed using test data. As a result, the models with high predictive power were linear regression model, Gaussian process regression model, and support vector machine. The proportion of training data and predictive power were not proportional. In addition, the average value of the difference between the predicted value and the measured value was not large, but when the measured value was high, the predictive power was decreased. The results of this study can be developed as a more systematic and precise fine dust prediction service by combining meteorological data and urban big data through local government data hubs. Lastly, it will be an opportunity to promote the development of smart industrial complexes.

Permeability Reduction of Soil Filters due to Physical Clogging (물리적 폐색으로 인한 흙필터의 투수능 저하)

  • ;;;;Reddi, L. N.
    • Journal of the Korean Geotechnical Society
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    • v.17 no.1
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    • pp.15-24
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    • 2001
  • 흙필터는 일반적으로 침식이나 파이핑으로부터 지반 구조물을 보호하기 위하여 사용된다. 세립자들이 유동하여 필터에 퇴적하는 폐색현상이 발생하는 경우, 간극수압이 증가하고 이로 인해 지반구조물의 불안정을 유발시키게 된다. 미세입자의 유동에 의한 폐색현상은 옹벽의 뒤채움재에 설치한 필터, 흙댐의 저부에 설치된 필터, 그리고 터널의 라이닝 뒤에 설치한 필터 등에서 발생할 수 있다. 폐색현상은 필터의 투수능을 저하시켜 배수능력에 상당한 위험을 초래할 수 있다. 본 연구에서는 필터의 폐색으로 인한 투수능 저하 정도를 실험을 통해 관찰하고 이론적인 모델을 통해 정량화 시키고자 하였다. 일정한 농도의 현탁액이 필터로 유입되는 분리형 실험과 현장상태를 모사하는 흙-필터 시스템의 결합형 실험을 통해 투수능의 저하현상이 압력 제어조건과 유량 제어조건에서 관찰되었고, 서로 비교 분석되었다. 미세입자가 통과하는 필터의 간극을 모세관으로 가정한 후 모세관에서 유체의 흐름 원리를 이용하여 물리적인 폐색에 의해 발생하는 투수능 저하현상을 이론적인 모델로 구성하였다. 일반적으로 투수능은 1/10 수준으로 감소되었으며, 분리형 실험에 의한 결과와 이론적인 모델의 결과는 잘 일치하였다. 또한, 결합형 실험결과와 분리형 실험결과가 비교적 잘 일치하여 투수능 저하예측은 분리형 실험이나 이론적 모델에 의하여 가능하리라 판단되었다.

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Comparing Microscale Behaviors of Block Copolymer with Polymer Blend Thin Films under Electric Fields (전기장 하에서의 블록 공중합체와 고분자 블렌드의 미세 구조 변화 거동 비교)

  • Bae, Joonwon
    • Applied Chemistry for Engineering
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    • v.29 no.4
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    • pp.395-398
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    • 2018
  • In this work, profound microscale behaviors of block copolymer and polymer blend under electric field were investigated using microscopic methods and compared systematically. To this end, both the block copolymer and blend containing polyacrylonitrile (PAN) and poly(methyl methacrylate) (PMMA) were introduced. The two polymers have a similar dielectric constant. Under an identical experimental condition such as temperature, film thickness, field intensity, and exposure time, the polymer blend responded more sensitively than the block copolymer. The presence of covalent bond suppressed the mobility of constituents in block copolymer. This study will be essential for future research activities regarding behaviors of polymeric materials under external fields.

국산 골판지 고지를 재활용한 골판지 원지의 강도 극대화 기술

  • 최병수;류정용;김용환;신종호;송봉근
    • Proceedings of the Korea Technical Association of the Pulp and Paper Industry Conference
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    • 2001.04a
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    • pp.158-158
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    • 2001
  • 산업용 포장재의 주원료로서 이용되고 있는 국산골판지고지(KOCC)는 반복적인 재활용 으로 인하여 섬유장이 짧고 매우 각질화된 상태이며, 펄프 내 미세분 함량이 50%이상에 달 하고 있다. 또한 섬유의 표면이 인쇄잉크, stickies 및 각종 이물질로 오염됨에 따라, 섬유자 체가 보유하고 있는 섬유간 결합 능력이 저하된 상태이다. 국산 골판지 고지를 재활용한 골판지 원지의 생산 시 탈수성 및 강도 저하의 단점을 극 복하는 것은 생산성과 품질향상의 측면이외에 고지 재생을 촉진시킨다는 의미를 지니고 있다. 상기한 KOCC의 단점을 극복하는 방안으로 섬유분과 미세분의 적절한 분급을 통하여 초지 시 탈수저향을 감소시키고 더불어 종이의 강도를 개선하는 방안이 본 연구센터에 의해 고안되었다. 아울러 고온압착건조 처리를 활용한 종이의 물성 개선법이 국내에 이미 적용된 상태로 건조시간의 단축 및 종이의 제반물성을 개선시켜주게 되었다. 하지만 이미 열화된 KOCC에 고온압착건조 처리를 적용하여 밀도를 증가시킨다 할지라 도 천연의 UKP를 이용한 종이에 준 하는 강도를 얻는 데에 한계가 있었다. K KOCC 펄프의 섬유간 결합 능력을 개선시키기 위하여 본 연구에서는 Kneading처리와 지력증강제를 첨가를 함께 실시하는 방안을 검토하였으며, 고온압착건조된 골판지 원지의 표면에 코팅처리를 실시하여 그 효과를 분석하였다. 이를 통해 국산 골판지고지를 재활용한 골판지원지의 강도 극대화 방안을 탐색하고자 하였다.

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Fabrication Process and Mechanical Properties of Co-based Metal Bond in Diamond Impregnated Tools (다이아몬드 공구용 코발트계 합금 결합제의 제조 및 기계적 성질)

  • Lee, Gi-Seon;Jeong, Seung-Bu
    • Korean Journal of Materials Research
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    • v.10 no.8
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    • pp.532-539
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    • 2000
  • Co-0.5C-(15~20)Cr-20Ni-8W-(2~7)Fe alloy bond in diamond-impregnated abrasive tool was synthesized by ball-milling and mechanical alloying process. When the powders were mechanical alloyed for 6h, micro-welding in most metal powders was observed irrespective of addition of stearic acid. Without stearic acid in metal powders, partial-ly coarse powders were obtained, which could be unfaverable to the densification of composite of composite powders. The hot-pressed compacts showed rupture strength of 1100MPa and hardness of about $46H_{RC}$, respectively.

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The comparison of microtensile bond strength with immediate and delayed dentin sealing (즉시 상아질 봉쇄와 지연 상아질 봉쇄에 따른 상아질 접착의 미세인장 결합강도 비교)

  • Lee, Heung-Bae;Han, Chong-Hyun;Shim, Jun-Sung;Kim, Sun-Jai
    • The Journal of Korean Academy of Prosthodontics
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    • v.46 no.4
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    • pp.372-380
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    • 2008
  • Purpose: The purpose of this study was to evaluate the effect of various methods of dentin bonding agent application on microtensile bond strength between dentin and resin, using a 2-step etch-and-rinse dentin bonding agent. Material and methods: Twenty freshly extracted human molars were obtained and divided into 4 groups of 5 teeth. 2-step etch-and-rinse dentin bonding agent was used for all groups. The control specimens were prepared using a direct immediate bonding technique. The delayed dentin sealing (A, C) specimens were prepared using an indirect approach with delayed dentin sealing. For group A, resin was built-up on uncured dentin bonding agent, and for group C, resin was built-up on pre-cured dentin bonding agent. Preparation of the immediate dentin sealing (B) specimens also used an indirect approach with immediate dentin sealing immediately following preparation. All teeth were prepared for a microtensile bond strength test. Specimens were stored in water for 24 hours. Ten beams (1.0 ${\times}$ 1.0 ${\times}$ 11 mm) from each tooth were selected for testing. Bond strength data (MPa) were analyzed with a one-way ANOVA test, and post hoc comparison was done using the Scheffe's test. Results: The mean microtensile bond strengths of control group, B and C (DDS with pre-cure) were not statisticaaly different from each other at 32.7, 33.3, 34.2 MPa. the bond strength for group A (DDS without pre-cure), 19.5 MPa, was statistically different (P < .01) from the other 3 groups. Conclusion: When preparing teeth for indirect bonded restorations, DDS with pre-curing dentin bonding agent and IDS results in the same bond strength between dentin and resin. On the contrast, the bond strength was decreased when DDS without pre-curing dentin bonding agent was used.

CDK2AP1, a Cyclin-Dependent Kinase 2-Associated Protein, Interacts with Kinesin-1 through Kinesin Superfamily Protein 5A (KIF5A) (Cyclin-dependent kinase 1 결합 단백질 CDK2AP1은 kinesin superfamily protein 5A (KIF5A)을 매개로 Kinesin-1와 결합)

  • Myoung Hun Kim;Se Young Pyo;Young Joo Jeong;Sung Woo Park;Mi Kyoung Seo;Won Hee Lee;Sang-Hwa Urm;Mooseong Kim;Jung Goo Lee;Dae-Hyun Seog
    • Journal of Life Science
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    • v.33 no.7
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    • pp.531-537
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    • 2023
  • Intracellular and axonal transport is mediated by microtubule-dependent motor proteins, such as kinesins and cytoplasmic dynein. Kinesin moves along the microtubule to the positive end of the microtubule, while dynein moves to the negative end of the microtubule. Kinesin-1 was first identified as a kinesin superfamily protein (KIF) that functions in the intracellular transport of various cargoes, including organelles, neurotransmitter receptors, and mRNA-protein complexes, through interactions between the carboxyl (C)-terminal domain and the cargo. It interacts with other cargoes, but the adapter/scaffold proteins that mediate between kinesin-1 and the cargo have yet to be fully identified. In this study, a yeast two-hybrid screen was used to identify adapter proteins that interact with the C-terminal region of KIF5A. We found an association between the C-terminal region of KIF5A and the cyclin-dependent kinase 2-associated protein 1 (CDK2AP1), originally identified in malignant hamster oral keratinocytes. CDK2AP1 bound to the C-terminal region of KIF5A and did not interact with KIF3A (the motor of kinesin-2), KIF5B, KIF5C, and kinesin light chain 1 (KLC1). The C-terminal region of CDK2AP1 is essential for its interaction with KIF5A. When co-expressed in HEK-293T cells, CDK2AP1 and kinesin-1 co-immunoprecipitated and co-localized in the cells. These results suggest that the KIF5A-CDK2AP1 interaction serves as an adapter protein connecting kinesin-1 and the cargo when kinesin-1 transports cargo in cells.

Ultrastructural Changes in the Mantle of the Equilateral Venus, Gomphina veneriformis (Bivalvia: Veneridae) Exposed to TBTCl (TBTCl 노출에 의한 대복, Gomphina veneriformis (Bivalvia: Veneridae) 외투막의 미세구조적 변화)

  • Park, Jung-Jun;Kim, Seok-Ryel;Park, Myoung-Ae;Lee, Jung-Sick
    • The Korean Journal of Malacology
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    • v.27 no.3
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    • pp.213-221
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    • 2011
  • Equilateral venus, Gomphina veneriformis exposed to tribultyltin chloride (TBTCl) for 36 weeks was showed ultrastructural changes of the mantle. The fine mantle had 4-folds and its epidermal layer consisted of simple columnar epithelial cells and ciliated cells and secretory cells. Inner and outer epidermal layer covered connective tissue. The mantle exposed to TBTCl at 12 weeks was decreased cilia in the inner epidermal layer, and observed extension of the hemolymph sinus and destruction of the septum. At 20 weeks, it revealed vacuole formation and pycnosis in the cytoplasm, and scattered muscular fiber. After 28 weeks of exposure, the mantle revealed partially degenerative changes in the epidermal layer. In the ciliated cells, basal body was isolated from the cilia and rootlet complex and basal foot were scattered. The sarcolemma had debris fiber. At 36 weeks, it observed degenerative cells that it revealed disappearance of the cilia, atrophic nucleus, poorly membrane and destruction of the cresternae in the mitochondria, and increasing heterophagosome. The outer epithelial cell had necrotic nuclus, numeous lysosome and disappearance of the microvilli. Therefore, results of this study suggested that chronical TBTCl exposure in the Gomphina veneriformis induced the disorders of shell growth and physiological function with histopathological changes of the mantle.

The Carboxyl-terminal Tail of a Heterotrimeric Kinesin 2 Motor Subunit Directly Binds to β2-tubulin (Heterotrimeric Kinesin 2 모터 단백질의 Carboxyl-말단과 β2-tubulin의 결합)

  • Jeong, Young Joo;Park, Sung Woo;Kim, Sang-Jin;Lee, Won Hee;Kim, Mooseong;Urm, Sang-Hwa;Seog, Dae-Hyun
    • Journal of Life Science
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    • v.29 no.3
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    • pp.369-375
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    • 2019
  • Microtubules form through the polymerization of ${\alpha}-$ and ${\beta}-tubulin$, and tubulin transport plays an important role in defining the rate of microtubule growth inside cellular appendages, such as the cilia and flagella. Heterotrimeric kinesin 2 is a molecular motor member of the kinesin superfamily (KIF) that moves along the microtubules to transport multiple cargoes. It consists of two motor subunits (KIF3A and KIF3B) and a kinesin-associated protein 3 (KAP3), forming a heterotrimeric complex. Heterotrimeric kinesin 2 interacts with many different binding proteins through the cargo-binding domains of the KIF3s, but these binding proteins have not yet been specified. To identify these proteins for KIF3A, we performed yeast two-hybrid (Y2H) screening and found a specific interaction with ${\beta}2-tubulin$ (Tubb2), a microtubule component. Tubb2 was found to bind to the cargo-binding domain of KIF3A but did not interact with KIF3B, KIF5B, or kinesin light chain 1 in the Y2H assay. The carboxyl-terminal region of Tubb2 is essential for interaction with KIF3A. Other Tubb isoforms, including Tubb1, Tubb3, Tubb4, and Tubb5, also interacted with KIF3A in the Y2H screening. However, ${\alpha}1-tubulin$ (Tuba1) did not interact with KIF3A. In addition, an antibody to KIF3A specifically co-immunoprecipitated the KIF3B and KAP3 associated with Tubb2 from mouse brain extracts. In combination, these results suggest that a heterotrimeric kinesin 2 motor protein is capable of binding to tubulin and may transport it in cells.