• EDISON SW 활용 경진대회 논문집
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• 제6회(2017년)
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• pp.712-714
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• 2017

미병의 예방과 관리의 중요성이 거론되고 있으나, 미병에 대한 분류나 진단을 위한 확고한 근거가 미약한 상황으로서 미병 진단 인자 분류를 위한 생리시스템 모델 개발이 필요한 시점이다. 본 연구의 목적은 개발한 생리학적 모델이 미병 단계를 구별하는데 효과 및 유용성이 있는지를 임상 검증하기 위하여 생리학적 모델 인공지능 시뮬레이션을 개발하고자 함이다. 인공지능 계산은 3층으로 구성된 네트워크를 이용하였으며 각 층은 30개의 neuron들로 구성하였다. 인공지능망의 입력 값은 나이, 수축기 혈압, 이완기 혈압, 심박수 값 (입력 값 4개)이고 출력 값은 혈관 저항값인 Ra이다. 머신러닝 차수를 높이면서 인공지능을 사용하지 않은 생리적 모델로부터 도출된 결과와 인공지능을 통하여 계산된 결과를 비교하였다. 개발된 인공지능계산을 이용한 생리시스템 모델은 대량의 표본집단에서 임상 검증에 기여할 것이다.

• 한국콘텐츠학회논문지
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• 제22권8호
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• pp.671-680
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• 2022

본 연구의 목적은 한의학 기반 건강상태 및 진단 분류 도구인 미병과 한열설문의 웹 기반과 종이 기반 간의 일치도를 평가하는 것이다. 일반인 72명을 대상으로 웹 기반 조사를 먼저 시행하고, 시간 간격을 두고 종이기반 설문을 진행하였다. 웹과 종이 기반 조사 방법 간의 동등성은 급내상관계수(Intraclass Correlation Coefficient, ICC)와 Bland-Altman 방법으로 설문 점수 간의 일치도를 평가하였다. 미병설문은 웹과 종이 조사 간에 높은 신뢰도를 보였고(ICC=0.95, 95% CI 0.92 - 0.97), 한열설문의 한증(ICC=0.98, 95% CI 0.96 - 0.99)과 열증(ICC=0.9, 95% CI 0.83 - 0.93) 모두 우수한 신뢰도를 나타냈다. 두 조사 방법 간의 평균 점수 차이는 미병설문이 -0.25점이고, 한열설문의 한증 -0.17점, 열증 0.11점으로 유사한 일치 양상을 나타냈다. 대상자의 84%가 웹 기반에 긍정적인 만족도를 보였고, 80%가 웹 조사를 선호하였다. 본 연구에서 미병설문과 한열설문의 웹 조사 방법 간의 신뢰도와 실행 가능성을 확인하였다. 이것은 장기간 걸쳐 진행되는 코호트 연구에서 대상자 추적 관찰에 유용한 도구로 고려된다.

• 원자력산업
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• 제11권7호통권101호
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• pp.80-89
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• 1991

• 농약정보
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• 제21권1호통권154호
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• pp.42-43
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• 2000

• 동서간호학연구지
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• 제22권1호
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• pp.17-23
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• 2016

Purpose: The purpose of this study was to conduct a keyword analysis for exploring the symptoms of Mibyeong and related factors of Korean nurses from domestic nursing research journals from 2000 to 2015. Methods: A total of 63 studies were chosen for analysis using the keywords of "nurses", "fatigue", "pain", "sleep", "digestion", "depression", "anger", "anxiety", "stress", and "quality of life." Results: Fifteen out of 63 studies were published in the Journal of Korean Academy of Nursing Administration and studies were increasing rapidly since 2007. Keyword analysis revealed that majority of the studies were about stress, fatigue, and sleep disturbance. Symptoms of complaints in nurses were similar to those of Mibyeong in Korean Medicine. This study found that there was a need to utilize a feasible interventions in order to manage health in individuals. It is important to mange symptoms of Mibyeong in nurses since they are more vulnerable to it. Conclusion: The concept of Chi-Mibyeong may be helpful for nurses to promote their health as a prevention in Korean medicine before the onset of illness.

• 대한예방한의학회지
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• 제23권2호
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• pp.77-89
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• 2019

Objectives : In this study, We overviewed study trend on 'Mibyung' by analyzing articles published in Korea from 1997 to 2019. Methods : We collected research articles on 'Mibyung' from 7 Korean research databases using the keyword '미병' and '아건강'. Then we analyzed them by publish year, journal, and research subjects. Research subjects were categorized into 'diagnosis', 'relationship with other factors', 'trend', 'concept', 'application development', 'policy research', 'prevalence and recognition', 'clinical report' or 'animal study'. Results & Conclusions : The largest number of related articles was published in 2017(12 articles, 26.7%). 'Journal of Society of Preventive Korean Medicine' was the journal with the most published articles(16 articles, 35.6%). Most of the research subjects were about diagnosis(11 articles, 24.4%) and analysis on relationship with other factors(10 articles, 22.2%). Little were published on policy(4 articles, 8.9%) and clinical study(1 article, 2.2%). More research on policy and clinical trials should be implemented for future mibyung study.

• 한방비만학회지
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• 제20권2호
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• pp.178-192
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• 2020

Objectives: The present study aimed to compare the impacts of cognitive behavioral therapy (CBT) and behavioral treatment (BT) on weight loss and psychological outcomes among patients with three different subtypes of obesity: simple obesity, obesity with binge eating disorder, and obesity with depression. Methods: Embase, PubMed, the Cochrane Central Register of Controlled Trials, Research Information Sharing Service, and Korean Studies Information Service System were systematically searched for randomized controlled trials conducted on or before May 2020, that used CBT to treat obesity. Methodological quality was assessed using Cochrane's risk of bias tool 2 and publication bias was evaluated through the funnel plot using the trim and fill method, Egger's test, and Begg and Mazumdar rank correlation test. A meta-analysis was conducted using a random-effects model and the standardized mean difference with 95% confidence interval (CI) was used to determine effect size. Results: Twenty-one randomized controlled trials with a total of 22 intervention arms and 2,590 patients were included. Our study results revealed that the effects of CBT, compared with BT, on weight loss distinctly differed across all patient subgroups. In the simple obesity group, CBT was more effective than BT (Hedges' g=0.138, CI=0.012~0.264); however, in the obesity with binge eating disorder group, BT was more effective than CBT (Hedges' g=-0.228, CI=-0.418~-0.038); in the obesity with depression group, the effect of CBT was not statistically different from that of BT (Hedges' g=0.276, CI=-0.307~0.859). Further studies with larger sample sizes are required to confirm the outcomes observed in this study. Conclusions: Our results indicated that the effects of CBT on obesity treatment vary based on patient subtype. Therefore, our findings suggest that CBT or BT should be selectively recommended as a treatment strategy for different obesity subtypes.

• 대한한의학원전학회지
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• 제19권2호통권33호
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• pp.310-315
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• 2006

아건강상태(亞健康狀態)에 처하여 있는 환자는 양의학적으로 뚜렷한 병리적 변화를 찾아보기가 쉽지 않다. 그러나 중의학의 병기이론을 근거로 하면 아건강상태(亞健康狀態)는 일정한 병리적 상태에 처한 것으로 인식된다. 즉 인체의 음양과 기혈이 편파(偏頗)되어 있으며 단지 그 변화가 초기단계에 있기 때문에 병태(病態)적 요인에 비하여 정도(程度)적인 차이가 있는 것으로 인식된다. 중의학이 건강에 대한 인식은 ‘천인상응(天人相應)’과 ‘음평양비(陰平陽秘)’, ‘정신내치(精神乃治)’란 관념이다. 주로 사람과 자연환경 및 외부사회간의 상호관계, 그리고 체내의 음양조화를 이룬 동태평형(動態平衝)을 중요시한다. 즉 인체의 기혈평형과 장부기능의 협조(協調)를 강조하고 기기(氣機)의 조창(調暢)이 건강의 근본(根本)이라고 인식한다. 시대적인 관계로 중의학에는 아건강상태(亞健康狀態)란 용어가 없지만 2000여년 전(前)에 성서(成書)된 중의학의 경전거작(經典巨作)인 ${\ulcorner}$내경(內經)${\lrcorner}$ 속에 일찍이 ‘미병(未病)’이란 개념(槪念)과 치미병(治未病)의 관념을 제출하였다. 이는 중의학이 미병선방(未病先防)의 의학사상을 나타내었고 주로 치병지미성(治病之未成), ‘치기미전(治其未傳)’, ‘차후방복’등 세 가지 방면의 내용을 제시된다. 또한 중의학은 양생학(養生學)에 대하여 특별히 중시하였고,${\ulcorner}$내경(內經)${\lrcorner}$에 대량(大量)의 편폭(篇福)으로 어떻게 양생하고 정기(正氣)를 보호해야 한다는 방법이 소개 되어 있다. 후세(後世) 역대의가(歷代醫家)는 그 내용을 더욱 충실(充實)케 하고 발전시켰다. 근대(近代)에 이르러서 중의학술(中醫學術)에 특유한 내용인 '미병학(未病學)'이 형성되었고, 그 이론체계 속에 아건강상태(亞健康狀態)의 예방과 치료에 관한 내용이 포함되어 있다.

• 대한한의학회지
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• 제43권1호
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• pp.112-135
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• 2022

Objectives: The objective of this study was to summarize clinical studies conducted over the last five years that investigated the effect of acupuncture on Parkinson's disease and to propose a better process of study. Methods: Research Information Sharing Service (RISS), Korea Studies Information Service (KISS), Cochrane Central Register of Controlled Trials (CENTRAL), PubMed, Embase, and China National Knowledge Infrastructure (CNKI) were systemically searched for clinical trials that had investigated the effect of acupuncture on the course of Parkinson's disease from May 2016 to April 2021. Results: A total of 23 studies met all the inclusion criteria. In most reports, acupuncture had significant positive effects on the course of Parkinson's disease. Furthermore, there were no serious adverse events associated with acupuncture in any of the studies. In addition to the acupuncture methods that showed effectiveness in previous studies, various types of acupuncture have been used to treat sub-symptoms of Parkinson's disease. The outcome measures were subdivided through individual symptom evaluation and mechanical analysis. Follow-up assessments were also performed to analyze the continuous effect. Conclusion: In the clinical studies conducted over the last five years, many studies investigated the various types of acupuncture used to treat Parkinson's disease and the segmentation and diversification of outcome measures focusing on individual symptoms, and a new approach for excluding placebo effects through follow-up studies has been made. Further attempts like these are needed to overcome methodological flaws in studies on the effects of acupuncture on Parkinson's disease.

• 한방비만학회지
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• 제22권2호
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• pp.136-146
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• 2022

Objectives: The objective of this study is to evaluate weight change and analyze adverse events in overweight and obese women with polycystic ovary syndrome (PCOS) who were prescribed with Gamitaeeumjowee-tang. Methods: A retrospective chart review was conducted for medical records of patients with PCOS, who were administered with Gamitaeeumjowee-tang for a period of 12 weeks between January 2019 and December 2021. Outcomes were total weight loss/weight loss rate, the percentage of patients who lost more than 5% and 10% of their baseline weight. Adverse events (AEs) reported by patients were evaluated by severity, causality and system-organ classes. Results: A total of sixty-seven patients were included (mean±standard deviation, Age 28.78±5.25 years, weight 76.78±12.84 kg, body mass index 29.2±4.26 kg/m²). The average total weight loss in PCOS patients was 6.57±3.07 kg and the average weight loss rate was 8.55±3.65%. The percentage of patients with more than 5% and 10% weight loss compared to their baseline weight was 86.56% and 25.37% respectively. The analysis of adverse events are as follows: Causality assessment with World Health Organization-Uppsala Monitoring Centre of AEs showed 'Unlikely' was the most common (71.7%) and severity evaluations with Common Terminology Criteria for Adverse Events showed almost all symptoms were mild (98.9%). Conclusions: Gamitaeeumjowee-tang helps to lose weight of PCOS patients, which is overweight or obese, and no serious adverse events have occurred. Additional well-designed clinical studies are recommended.