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http://dx.doi.org/10.15429/jkomor.2022.22.2.136

Gamitaeeumjowee-tang for Weight Loss in Overweight and Obese Women with Polycystic Ovary Syndrome: A Retrospective Chart Review  

Min-jeong Park (Nubebe Korean Medical Clinic Gangnam Center)
Eunjoo Kim (Nubebe Mibyeong Research Institute)
Ji-Myung Ok (Nubebe Korean Medical Clinic Gangnam Center)
Ka-Hye Choi (Nubebe Korean Medical Clinic Hongdae Center)
Young-Woo Lim (Nubebe Mibyeong Research Institute)
Publication Information
Journal of Korean Medicine for Obesity Research / v.22, no.2, 2022 , pp. 136-146 More about this Journal
Abstract
Objectives: The objective of this study is to evaluate weight change and analyze adverse events in overweight and obese women with polycystic ovary syndrome (PCOS) who were prescribed with Gamitaeeumjowee-tang. Methods: A retrospective chart review was conducted for medical records of patients with PCOS, who were administered with Gamitaeeumjowee-tang for a period of 12 weeks between January 2019 and December 2021. Outcomes were total weight loss/weight loss rate, the percentage of patients who lost more than 5% and 10% of their baseline weight. Adverse events (AEs) reported by patients were evaluated by severity, causality and system-organ classes. Results: A total of sixty-seven patients were included (mean±standard deviation, Age 28.78±5.25 years, weight 76.78±12.84 kg, body mass index 29.2±4.26 kg/m2). The average total weight loss in PCOS patients was 6.57±3.07 kg and the average weight loss rate was 8.55±3.65%. The percentage of patients with more than 5% and 10% weight loss compared to their baseline weight was 86.56% and 25.37% respectively. The analysis of adverse events are as follows: Causality assessment with World Health Organization-Uppsala Monitoring Centre of AEs showed 'Unlikely' was the most common (71.7%) and severity evaluations with Common Terminology Criteria for Adverse Events showed almost all symptoms were mild (98.9%). Conclusions: Gamitaeeumjowee-tang helps to lose weight of PCOS patients, which is overweight or obese, and no serious adverse events have occurred. Additional well-designed clinical studies are recommended.
Keywords
Polycystic ovary syndrome; Overweight; Obesity; Weight loss; Korean traditional medicine;
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Times Cited By KSCI : 5  (Citation Analysis)
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