• Title/Summary/Keyword: 맞춤변형

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Dental Hygienist-Led Dental Hygiene Process of Care for Self-Support Program Participants in Gangneung (강릉시 자활근로사업 참여자 대상 치위생 과정 사례보고)

  • Yoo, Sang-Hee;Kwak, Seon-Hui;Lee, Sue-Hyang;Song, Ga-In;Bae, Soo-Myoung;Shin, Sun-Jung;Shin, Bo-Mi
    • Journal of dental hygiene science
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    • v.18 no.6
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    • pp.327-339
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    • 2018
  • This study aimed to provide basic data for establishing the clinical basis for dental hygienist-led dental hygiene process of care by identifying multiple risk factors for self-support program participants in Gangneung city; we also compared oral health status and behavioral changes through customized oral health care. Four dental hygienists who were evaluated for degree of conformity provided dental hygiene process of care to eight self-support program participants who were selected as having an oral health risk among people in the self-support center. The clinical indicators measured during dental hygiene assessment and evaluation and behavioral changes due to dental hygiene intervention were compared and analyzed. With respect to clinical indicators, at the time of probe, the retention rate of patients with gingival bleeding decreased from 61.4% to 14.7% after intervention (p=0.004). Furthermore, the retention rate of patients with a periodontal pocket >4 mm decreased from 15.6% to 5.8% (p=0.001). The average modified O'Leary index of the patients improved from 23 to 40 (p=0.002). Previously, all eight subjects used the vertical or horizontal method of brushing; after dental hygiene care interventions regarding method and frequency of toothbrushing, use of oral care products, and individual interventions, they started using the rolling or Bass method of toothbrushing. Four of eight subjects reported using interdental toothbrushes after intervention. As a result of applying the change model to the transtheoretical behavior change of the subject, the result of strengthening the health behavior was confirmed. For promotion of oral health by the prevention-centered incremental oral health care system, dental hygienist-led dental hygiene management and maintenance is essential. It is thought that continuous research, such as for feasibility evaluation, cost benefit analysis, and preparation of legal systems, is needed to establish and activate dental hygiene management.

Inter-fractional Target Displacement in the Prostate Image-Guided Radiotherapy using Cone Beam Computed Tomography (전립선암 영상유도 방사선 치료시 골반내장기의 체적변화에 따른 표적장기의 변화)

  • Dong, Kap Sang;Back, Chang Wook;Jeong, Yun Jeong;Bae, Jae Beom;Choi, Young Eun;Sung, Ki Hoon
    • The Journal of Korean Society for Radiation Therapy
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    • v.28 no.2
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    • pp.161-169
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    • 2016
  • Purpose : To quantify the inter-fractional variation in prostate displacement and their dosimetric effects for prostate cancer treatment. Materials and Methods : A total of 176 daily cone-beam CT (CBCT) sets acquired for 6 prostate cancer patients treated with volumetric-modulated arc therapy (VMAT) were retrospectively reviewed. For each patient, the planning CT (pCT) was registered to each daily CBCT by aligning the bony anatomy. The prostate, rectum, and bladder were delineated on daily CBCT, and the contours of these organs in the pCT were copied to the daily CBCT. The concordance of prostate displacement, deformation, and size variation between pCT and daily CBCT was evaluated using the Dice similarity coefficient (DSC). Results : The mean volume of prostate was 37.2 cm3 in the initial pCT, and the variation was around ${\pm}5%$ during the entire course of treatment for all patients. The mean DSC was 89.9%, ranging from 70% to 100% for prostate displacement. Although the volume change of bladder and rectum per treatment fraction did not show any correlation with the value of DSC (r=-0.084, p=0.268 and r=-0.162, p=0.032, respectively), a decrease in the DSC value was observed with increasing volume change of the bladder and rectum (r=-0.230,p=0.049 and r=-0.240,p=0.020, respectively). Conclusion : Consistency of the volume of the bladder and rectum cannot guarantee the accuracy of the treatment. Our results suggest that patient setup with the registration between the pCT and daily CBCT should be considered aligning soft tissue.

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Improvement of Artificial Antibody Secretion Using Supercharged Protein (단백질의 과전하화를 이용한 인공 항체의 분비 개선)

  • Park, Jiyeon;Choi, Heeju;Lee, Hyejin;Ahn, Jung Hoon
    • Journal of Life Science
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    • v.30 no.5
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    • pp.420-427
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    • 2020
  • A repebody, an artificial non-immunoglobulin protein scaffold, is expected to be a solution in the search for faster, cheaper, and customizable antibodies. However, the production of medical repebodies remains difficult due to their low yield and the complex purification processes required. The Pseudomonas fluorescens ABC transporter system has been suggested as an efficient and cost-effective method for repebody production, but the total yield is low because of the secreted protein's positive charge; thus, a repebody with a high isoelectric point needs to be changed into a more negatively charged protein for better secretion. To achieve this, we first attached oligo-aspartic acids to the N- and C-terminals of the repebody, but secretion efficiency was not enhanced significantly. Subsequently, we devised an alternative method for improved secretion efficiency by engineering fifteen positively charged amino acids to aspartic acid in the non-antigen binding sites of the repebody to give a high net negative charge. As a result, secretion efficiency was greatly enhanced from 21.2% (wildtype) to 58.5% (negatively supercharged). The negatively supercharged repebody was succussfully produced extracellularly by ABC transporter secretion system in P. fluorescens.

Mechanical Properties of Laser-Welded Multi-Material Tailor-Welded Blanks (레이저 TWB된 이종접합강의 기계적 특성)

  • Nam, Ki-Woo;Park, Sang-Hyun;Lee, Kyu-Hyun;Lee, Mun-Yong
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.36 no.8
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    • pp.857-863
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    • 2012
  • In this study, tailor-welded blanks(TWB) were formed between high-strength steel(SABC1470) and cold rolled steels(SPFH590 and SPFC980) to improve passenger safety and reduce the weight of cars. Multi-material TWB specimens were highly strengthened through the heat treatment of SABC1470. The change in tensile strength caused by the stand-by time until water cooling after stamping and the deformation behavior of high-speed bending in a statically indeterminate condition such as in the center-pillar were evaluated. Multi-material TWB specimens that were heat-treated at the same temperature tended to show a decrease in tensile and yield strength, depending on the stand-by time until water cooling. On the other hand, Multi-material TWB specimens(SABC1470+SPFH590) that were heat treated at $850^{\circ}C$ showed good properties that were suitable for ensuring passenger safety in car accidents. From the viewpoint of passenger safety, it is best to use SABC1470 and SPFH590 in the upper and lower area of the center-pillar, respectively.

A Case Study on the Influence of Science Education Courses on Pre-service Chemistry Teachers' View of Learning (예비화학교사가 수강한 과학교육 과목이 학습관에 미치는 영향에 관한 사례연구)

  • Koh, Eun-Jung;Choi, Byung-Soon
    • Journal of the Korean Chemical Society
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    • v.58 no.1
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    • pp.105-117
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    • 2014
  • The purpose of this study was to analyze pre-service chemistry teachers' view of learning focused on the influence of science education courses that pre-service chemistry teachers had learned. Three pre-service chemistry teachers were selected for this study. Documents related to science education courses, survey data about their view of learning and interview data were collected, transcribed and analyzed. According to this study, pre-service chemistry teachers had changed, modified, maintained and strengthened their view of learning while they took the science education courses. Pre-service teacher K and P had changed their traditional view to the constructive view and then had modified their view by adding the reality. And pre-service teacher H had modified his constructive view with some traditional view. All Pre-service teachers had modified their own view of learning because of the science education course that emphasized the real field situation. As discussed above, science education courses focused on the applying the theory to real teaching situation gave the opportunity to modify pre-service teachers' own view of learning. It implied that the science education courses learned in the teachers college have to include contents based on real teaching situation and pre-service teachers' reflective thinking processes for establishing their view of learning and customized teaching activities.

Analysis of Electrochemical Characteristics of the Rechargeable $LiMn_2O_4$ Thin Film Battery (재충전이 가능한 박막전자용 $LiMn_2O_4$ 박막 전지의 전기화학 특성 분석)

  • Kim Joo-Seok;Jung Hunjoon;Kim Chan-Soo;Joo Seung-Ki
    • Journal of the Korean Electrochemical Society
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    • v.3 no.3
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    • pp.131-135
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    • 2000
  • In order to investigate the origin of capacity fading with charge/discharge cycling in $LiMn_2O_4$ thin film battery, impedance studies have been performed with increasing cycling in $LiMn_2O_4/1M\;LiClO_4-PC/Li$ cells. The fitted values obtained from impedance data show good agreements with the experimental results. Especially, the element of charge transfer resistance of $LiMn_2O_4/liquid$ electrolyte interface initially increased, and then saturated with increasing the charge/discharge cycles, which could explain the cause of initial abrupt capacity fading of $LiMn_2O_4$ thin film with cycling due to interfacial reaction. The steady capacity fading is caused by the increasing of Warburg resistance. The chemical diffusion coefficient of Li ions decreased from $5.15\times10^{-11}cm^2/sec$ at 1st cycles to $6.3\times10^{-12}cm^2/sec$ at 800th cycles, which attributed to the Jahn-Teller distortion/Mn dissolution which diminishes tetra hedral sites necessary for Li diffusion in $LiMn_2O_4$.

Estimation of Attenuation Relationship Compatible with Damping Ratio of Rock Mass from Numerical Simulation (수치해석을 통한 진동감쇠식 맞춤형 암반의 감쇠비 산정)

  • Kim, Nag Young;Ryu, Jae-Ha;Ahn, Jae-Kwang;Park, Duhee;Son, Murak;Hwang, Young-Cheol
    • Journal of the Korean Geotechnical Society
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    • v.31 no.4
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    • pp.45-55
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    • 2015
  • The stability of the adjcent structures or slopes under blasting is typically evaluated using an empirical vibration attenuation curve or dynamic numerical analysis. To perform a dynamic analysis, it is necessary to determine the blast load and the damping ratio of rock mass. Various empirical methods have been proposed for the blast load. However, a study on representative values of damping ratio of a rock mass has not yet been performed. Therefore, the damping ratio was either ignored or selected without a clear basis in performing a blast analysis. Selection of the dampring ratio for the rock mass is very difficult because the vibration propagation is influenced by the layout and properties of the rock joints. Besides, the vibration induced by blasting is propagated spherically, whereas plane waves are generated by an earthquake. Since the geometrical spreading causes additional attenuation, the damping ratio should be adjusted in the case of a 2D plane strain analysis. In this study, we proposed equivalent damping ratios for use in continuum 2D plane strain analyses. To this end, we performed 2D dynamic analyses for a wide range of rock stiffness and investigated the characteristics of blast vibration propagation. Based on numerical simulations, a correlation between the attenuation equation, shear wave velocity, and equivalent damping ratio of rock mass is presented. This novel approach is the first attempt to select the damping ratio from an attenuation relationship. The proposed chart is easy to be used and can be applied in practice.

A Study on the Development Method of e-Learning Contents by the Level of Demand for Landscaping Practical Education - Development and Reuse of Modular Learning Objects - (조경실무 교육수요 수준별 이러닝 콘텐츠 개발 방법론 - 모듈형 학습객체 개발과 재사용을 중심으로 -)

  • Choi, Ja-Ho
    • Journal of the Korean Institute of Landscape Architecture
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    • v.46 no.3
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    • pp.1-13
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    • 2018
  • Landscape Architecture is a minority manpower field that requires wide knowledge and experience. Therefore, the service market is narrower than other fields, and education service for practitioners is lacking. The purpose of this study is to propose e-learning content development methodology that can provide customized landscaping practical education according to the level of education and increase the economic efficiency of the development process. First, in theoretical review, the ADDIE model was modified to select the curriculum development model that pursues efficiency and introduced the concept of reusing learning objects in the SCORM-based model. In particular, to overcome the problems presented in the precious studies, the analysis and design stages have been strengthened and faculty designers with integrated knowledge of Landscape Architecture and ICT have led the overall phase. The actual development process is based on a step by step procedure--analysis of landscaping practitioners needs and environments, etc., teaching and learning procedures and the design of activities considering contents reuse, the first development such as actual shooting and editing, and the second development reusing the first development content--and was done in the order of evaluation and revision of professionalism and satisfaction. As a result of the study, the space-based courses composed of modular learning objects were first developed as 216 courses in 8 subjects, as 208 courses in 3 subjects in total, in which the modularized learning object are crossed and combined in units and difficulty-based courses were second developed in 216 courses with 3 subjects in total. As a result of the evaluation the satisfaction assessment of the overall satisfaction was 4.20 and the average value of the eight measures was 3.97, both being close to 4.0. For the professional assessment, the scores of 8 subjects were very high at 84.8 to 96.4 points. in context, the scores of 5 subjects were equal to from 89.9 to 96.4 points. In conclusion, as the study was conducted based on a clear understanding of the digital characteristics of e-learning contents and general characteristic of the landscaping industry, it was possible to develop a curriculum by developing a course composed of modular learning objects and reusing learning objects by unit. In particular, it has been proven to be effective in conveying professional knowledge and experiences via general procedures and provided an opportunity to overcome some analog problems that may occur in offline education. In the future, further studies need to be done by expanding the content and by focusing on segmented subjects.