• Journal of the Korean Chemical Society
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• v.48 no.6
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• pp.616-622
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• 2004

Liposome powders were prepared by a freeze-drying method for the application to the field of drug carrier. The effect of maltose as a liposome stabilizer was studied on the stability and the drug-loading efficiency of the freeze-dried liposome powders. The particle size of liposomes before and after freeze-drying was determined to evaluate the liposome stability. The drug-loading efficiency was measured by Fluorescence spectrophotometer using calcein as a model drug. When maltose was added after the preparation of the liposomes, the liposomes was stable, compared to the case of maltose addition at the hydration procedure. By the addition of maltose, the liposome was stable for 30 days at $4{\sim}37^{\circ}C$, while the particle size of the liposome without maltose increased with time. The liposome showed relatively high stability when the maltose/lipids molar ratio was 3 and 6.

• 핵융합뉴스레터
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• s.48
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• pp.20-21
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• 2010

진공(眞空), 말 그대로 텅 빈 공간을 뜻하는 단어로 철학적으로는 완전하게 빈 상태를 말하지만, 과학 기술적으로는 대기압보다 낮은 압력 상태를 진공이라 부른다. 진공을 뜻하는 영어단어 vacuum은 '비어 있음'을 의미하는 그리스어로부터 유래하는데 원자론의 창시자인 데모크리토스가 2,400년 전 자연이 원자와 진공으로 되어 있다고 주장하며 처음 등장한 것으로 꽤 오래전에 제시된 개념이다. 진공상태에서 나타나는 특성들은 다양한 산업과 공학에서 유용하게 활용되면서 현대 사회에 가장 밀접한 개념이 되고 있다. 텅 비어 있는 이 공간은 놀라울 만큼 많은 것을 얻을 수 있고 새로운 일들을 가능하게 한다.

• Proceedings of the Korea Information Processing Society Conference
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• 2005.05a
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• pp.373-376
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• 2005

유비퀴토스 환경에서 차세대 LBS(Location-Based Service) 서비스를 위한 콘텐츠를 제공하기 위해 각 단말기와 환경 및 사용자의 취향에 맞게 콘텐츠를 리퍼포징(Repurposing)해야 한다. 콘텐츠 리퍼포징이란 유비퀴토스 환경 구축에 필수적인 핵심 기술로서, 하나의 원본 콘텐츠를 사용자의 선호도, 단말기 특성, 네트워크 특성 등에 따라 최적의 상태로 적응/변환하여 제공함을 말한다. 본 논문에서는 다양한 사용자에게 차세대 LBS 서비스를 위해 콘텐츠의 사용자 정보와 콘텐츠 관련 환경 정보 등을 분석, 전달하기 위한 방법론을 제안하고, 또한 리퍼포징된 콘텐츠의 다양한 정보 분석 방법을 제공하기 위한 미들웨어 아키텍처를 설계한다. 이는 학문적으로 새로운 최첨단의 이론과 기술을 창출하고 이를 기반으로 차세대 LBS 서비스 분야에 혁신적인 역할을 할 것으로 기대된다.

• Journal of the Korean Society of Food Science and Nutrition
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• v.33 no.6
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• pp.951-957
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• 2004

Hypoglycemic effect of Prunus mume (PM) extract containing in Sangjinyangheul-tang and Hwangkeumtang, one of the diabetic herbal medicines, was determined by investigating insulin-like action, insulin sensitizing action and a-glucoamylase suppressing action. Insulin-like activity of 3T3-L1 fibroblast was not shown with the treatment of PM methanol extracts. However, treatment with 20% or 40% PM methanol extracts and differentiation inducers significantly decreased the differentiation of 3T3-L1 fibroblasts to adipocytes. A significant insulin sensitizing activity was observed in 3T3-L1 adipocytes, giving PM extracts (60%, 80% and 100%) with 1 ng/mL insulin to reach glucose uptake level increased by 50 ng/mL of insulin alone. In addition, 20% and 40% methanol extracts of PM suppressed the a-glucoamylase activity by 30% in vitro. However, there was no significant differences in the peak of serum glucose levels and area under the curve in Sprague Dawley male rats treated with PM ethanol extract or cellulose and 2 g maltose or dextrin/kg body weight. These data suggested that PM extracts contain effective insulin sensitizing compounds, lipid synthesis suppressing compounds and possibly a-glucoamylase suppressing compounds. Therefore, PM extracts are beneficial for anti-diabetic treatment in obese diabetic patients.

• The Korean Journal of Food And Nutrition
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• v.10 no.1
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• pp.102-109
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• 1997

The structures of novel branched oligosaccharides synthesized by the acceptor reaction with dextransucrase from Leuconostoc mesenteriodes M-12 were proposed in accordance with the results obtained from enzymatic hydrolyses and a partial acid hydrolysis. The structure of branched oligosaccharide B4 was shown to be 62-O-$\alpha$-D-kojibiosylmaltose. Branched oligosaccharide B5 was shown to be 63-O-$\alpha$-D-kojibiosylpanose. By reacting the acceptor reaction products with endodextranase a novel branched oligosaccharide (D4) could be produced. D4 was derived from the result of endodextranase hydrolysis of oligosaccarides synthesized by the second acceptor reaction with dextransucrase and was resistant to endodextranase and glucoamylase. The proposed structure of D4 was 62-O-$\alpha$-D-kojibiosylisomaltose. Formation pattern of the acceptor reaction products smaller than d.p. 6 with linear or branched linkage was also shown.

• Applied Biological Chemistry
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• v.21 no.2
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• pp.103-108
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• 1978

Acid-stable ${\alpha}-amylase$ was partially purified from Paecilomyces subglobosum by Sephadex G-150 gel filtration. About 7.7-fold purification was obtained and the partially purified preparation has 5.0 U of ${\alpha}-amylase$ activity per mg of protein. Using this partially purified ${\alpha}-amylase$, general properties were studied and it showed the maximal activities at the conditions of pH 4.0 and $38^{\circ}C$. High stability of the acid-stable ${\alpha}-amylase$ in acidic condition was observed, whereas thermal stability was similar to the conventional ${\alpha}-amylase$.

• The Korean Journal of Archival Studies
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• no.65
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• pp.365-396
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• 2020

I examined the archival basis of two historians who wrote history books with the same title of 'History'; Simaqian of ancient China and Herodotus of Halikarnassos. I examined a prejudice to these two history books, a misunderstanding of them as an imagination rather than a history. How can an imagination become a history? First, I explained the common characteristics found in their compilation and writing of 'History.' Simaqian and Herodotus did their field-works in historical sites, gathered oral-histories, and arranged archives they collected. These two historians heavily engaged in archival works in terms of verifying authenticity and reliability of their sources on the basis of historical empiricism. There are some misunderstanding on their archival endeavor and on the very nature of archives and historical studies as empirical studies. Furthermore, this misunderstanding regarding them as literature came from a confusion over the concept of literature. The creativity of literature is not equal to the "fictitiousness" of history despite historical works sometimes may give us an impression by the way of describing and providing insight into a certain event(s) and a person(s). As Herodotus said, a recognition of the differences of each race and human is a departure of historical archiving of the valuable experiences of human-beings. By doing so, natural results of archival behaviors, preservation of the records, and consistent inquiry of historian-archivists become a humanistic passage overcoming the current wrong trends of historical studies confined to a narrow nation-history.

• Korean Journal of Plant Resources
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• v.26 no.1
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• pp.9-18
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• 2013

The aim of this study is to provide the basic data for yacon [Samallanthus sonchifolius (Poepp. & Endl.) H. Robinson] in dietary food. The nutritional compositons, such as protein, ash, carbohydrate, dietary fiber, vitamin and fructooligosaccharide, were analyzed for 4 yacon germplasm lines. Yacon has low calories with only 46~56 kcal/100 g. The contents of water, fat, ash, protein, carbohydrate and dietary fiber were ranged 85.9~86.8%, 0.1~0.2%, 0.2~0.3%, 0.5~0.7%, 12.2~13.1% and 1.05~1.14%, respectively. The iodine-starch test did not show any color or precipitation reaction, which indicates that yacon has no starch content. However, in the absence of starch, yacon is rich in fluctooligosaccharide, which is between 9.6~11.1%. Maltose is present in the larger amount, followed by sucrose, glucose, and fructose in terms of free sugars. The analysis of minerals revealed that yacon contains potassium in the larger amount of 141~176 mg/100 g F.W., followed by magnesium at 8.2~10.6 mg, calcium, and sodium representing the least present mineral. Yacon proved to have a total of 17 types of amino acids, which are between 404.0~581.8 mg per 100 g of yacon. Glutamic acid, the main sweetening component, is present in the large amount of 94.0~182.2 mg/100 g F.W., followed by aspartic acid, arginine, and alanine. The proportion of the essential amino acid was 24.8~33.6%. Results of analysis also showed that yacon contains 0.001~0.024 mg, 0.03~0.11 mg, 0.02~0.3 mg, 0.3~0.4 mg and 14.1~20.6 mg of ${\beta}$-carotene, thiamin, riboflavin, niacin, and ascorbic acid, respectively. It is also likely to be highly used as functional food material in the future because it is abundant in both fluctooligosaccharide and antioxidants which are important functional components.

• Journal of Korean Philosophical Society
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• v.130
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• pp.187-218
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• 2014

Nietzsche stellt in seiner Philosophie den "${\ddot{U}}bermensch$" als existenziales Ideal des Menschen sowie als Menschentyp der Zukunft und "die ${\ddot{u}}bermenschliche$ Zukunft" als Zukunft des gesunden Menschen vor. Der ${\ddot{U}}bermensch$ und die ${\ddot{u}}bermenschliche$ Zukunft beinhalten in Nietzsches Philosophie den Sinn des gesunden Menschen und seiner gesunden Zukunft. Nach Nietzsche kann dieses gesunde Ideal durch die aktive Praxis des Menschen endlich verwirklicht werden. Nietzsche unterscheidet das aktive und das passive Verhalten des Menschen und leitet daraus die zwei $gegens{\ddot{a}}tzlichen$ Menschentypen her, also den aktiven Menschen (Herr der Moral des Lebens - geistig Starker) und den passiven Menschen (Sklave der Moral des Lebens - geistig Schwacher). Aber die Typologie dieser anthropologischen Differenz zielt nicht auf die Dualisierung der absoluten Differenz, sondern auf seine relativistisch-relationale ${\ddot{U}}berwindung$. Auf diese Weise setzt die philosophische Anthropologie Nietzsches im Grunde seine eigene praktische Philosophie voraus. Ferner bestimmt Nietzsche den Menschen als Zwischenwesen, das $hei{\ss}t$, dass der Mensch in Also sprach Zarathustra an der existenzialen Grenze zwischen Tier und ${\ddot{U}}bermensch$ und in seiner anthropologischen ${\ddot{A}}sthetik$ an der ${\ddot{a}}sthetischen$ Grenze zwischen $Versch{\ddot{o}}nerung$ und $Verh{\ddot{a}}sslichung$ des Lebens steht, sowie als $M{\ddot{o}}glichkeitswesen$, das an dieser Grenze durch die existenziale $Selbst{\ddot{u}}berwindung$ und die ${\ddot{a}}sthetische$ Selbstgestaltung in jedem Moment seine $Ver{\ddot{a}}nderungsm{\ddot{o}}glichkeit$ $sch{\ddot{o}}pferisch$ verwirklichen kann. Das Ziel dieser Arbeit ist es, aufgrund Nietzsches anthropologischen $Verst{\ddot{a}}ndnisses$ die anthropologische Methodologie zu $er{\ddot{o}}rtern$, die er $f{\ddot{u}}r$ die Verwirklichung der immanenten $Ver{\ddot{a}}nderungsm{\ddot{o}}glichkeit$ des Menschen in seiner Philosophie vorstellt.