• The Journal of Internal Korean Medicine
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• v.30 no.3
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• pp.648-655
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• 2009

Peripheral neuropathy is a disease of multiple Peripheral nerves. Tingling, pins-and needles, numbness, burning and raw sensation are symptoms of peripheral neuropathy. These symptoms are frequently complained by patients who suffered from obstructive syndrome of Ki and blood (痺證). This case was reported to evaluate the effects of oriental medicine therapy on a patient with obstructive syndrome of Ki and blood (痺證). The subject was a female patient who had obstructive syndrome of Ki and blood (痺證). She complained of calf pain, cold sense, walking discomfort, insomnia, dyspepsia, anorexia etc. We administered the medicine with dispeling the cold pathogenic factor (寒邪), adjusting the constructive and defensive energy (調營衛), tonifying the Ki and blood (補氣血) by stage. After the treatment, the symptoms improved. This case suggests that oriental medicine therapy can be applicable to improve in symptoms with Peripheral neuropathy.

• The Journal of Korean Medicine
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• v.21 no.4
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• pp.242-247
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• 2000

Tingling, pins-and-needles, numbness, burning and raw sensations are the words frequently used by patients to describe such conditions as paresthesia and obstruction syndrome of Ki and blood, Obstruction syndrome of Ki and blood results from the complex elements of wind, cold and dampness and has a process of stagnating Ki, blood and meridian system, The subject was a male patient who had obstructive syndrome of Ki and blood, We administered the medication with dispeling the pathogenic factor, adjusting the constructive and defensive energy, tonifying the Ki and blood by stage. The subject reported reduced pain, an increased range of motion and improved hyperlipidemia.

• The Journal of Korean Medicine
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• v.23 no.1
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• pp.170-176
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• 2002

Diabetic Peripheral Polyneuropathy is one of the most distressing complications of diabetes, Drugs such as narcotic analgesics, tricyclic antidepressants, anticonvulsants and phenothiazines have been used to treat diabetic peripheral polyneuropathy, but these drugs are not very effective for the many patients and the side effects may become intolerable. In oriental medicine, usually the main etiology of diabetic Peripheral Polyneuropathy is insufficiency of Blood due to the state of dry-heat in the human body. Therefore, we use Bogan-tang to treat numbness of Diabetic Peripheral Polyneuropathy. Bogan-tang was administrated twice a day for 15 days, and VAS Scale was performed every day to evaluate numbness and insufficiency of blood. In both cases, numbness and insufficiency of blood were improved without any side effects. This study suggests that Bogan-tang is an effective drug in the treatment of Diabetic Peripheral Polyneuropathy.

• Journal of Sasang Constitutional Medicine
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• v.33 no.4
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• pp.65-77
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• 2021

Objective We report a case about a Soyangin patient with diabetic neuropathy. His symptoms were alleviated with Sasang Constitutional medicine. Methods A Soyangin patient with diabetic neuropathy was treated by herbal medicine, acupuncture, pharmacopuncture according to Sasang Constitutional Medicine. The progress was evaluated with numerical rating scale(NRS) and blood sugar test(BST). Results Sasang Constitutional Medicine seems to be effective for the symtoms of the patient with diabetic neuropathy in this case. Conclusions This case study shows that Sasang Constitutional Medicine may be an effective treatment for Soyangin's diabetic neuropathy.

• Journal of Korean Academy of Nursing
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• v.45 no.5
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• pp.661-670
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• 2015

Purpose: The purpose of this study was to examine the mediation of psychological distress in the relationship between disturbance in ADL from chemotherapy induced peripheral neuropathy and quality of life in order to provide a basis for planning nursing interventions to improve the quality of life in cancer patients. Methods: A purposive sample of 130 patients treated with chemotherapy were recruited in the cross-sectional survey design. Data were collected using self-report questionnaires. The instruments were the Chemotherapy Induced Peripheral Neuropathy Assessment Tool (CIPNAT), Hospital Anxiety Depression Scale (HADS), and Functional Assessment of Cancer Therapy-General (FACT-G). Results: The mean score for disturbance in ADL from chemotherapy induced peripheral neuropathy was 3.30. Overall quality of life was 2.48. The mean score was 1.04 for psychological distress. The prevalence was 35.4% for anxiety and 47.7% for depression. There were significant correlations among the three variables, disturbance in ADL from chemotherapy induced peripheral neuropathy, psychosocial distress, and quality of life. Psychosocial distress had a complete mediating effect (${\beta}$= -.74, p <.001) in the relationship between disturbance in ADL from chemotherapy induced peripheral neuropathy and quality of life (Sobel test: Z= -6.11, p <.001). Conclusion: Based on the findings of this study, nursing intervention programs focusing on disturbance of ADL management, and decrease of psychological distress are highly recommended to improve quality of life in cancer patients.

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.6
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• pp.1056-1060
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• 2011

To summarize and make a reference number of natural materials used to treat diabetic peripheral neuropathy. We surveyed all papers of diabetic peripheral neuropathy studies using natural materials in PubMed as "diabetic peripheral neuropathy AND plant", "diabetic peripheral neuropathy AND herbal", "diabetic peripheral neuropathy AND herb", etc. The number of papers, the formation of experiments, frequency of natural materials studies, and main studies were analyzed. Total 48 studies were finally selected. Of the papers, experiments with rats were the most common. Most studies were about fatty acids or herbal medicines. Rehmannia glutinosa, Cinnamomi Ramulus, Astragali Radix and so on were relatively studied much. This study produced an overview of worldwide natural materials used for diabetic peripheral neuropathy. This result may provide a valuable information of development of Korean herbal medicine used to treat diabetic peripheral neuropathy.

• Journal of Haehwa Medicine
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• v.13 no.2
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• pp.251-258
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• 2004

Two cases of in patients with diabetic peripheral neuropathy were reported in this clinical study. After the study, the results were as follows: 1. Diabetic peripheral neuropathy was occurred with both insulin dependent diabetic mellitus(IDDM) patients, long and short durations, and non insulin dependent diabetic mellitus(NIDDM) patients. However, the degree of subjective symptom was stronger with the former patients. 2. Non insulin dependent diabetic mellitus(NIDDM) patients on dosage of Gamisamultang (加味四物湯) showed remarkable decrease of duration of illness and pain; however, plantar causalgic pain was unremarkable. In contrast to non insulin dependent diabetic mellitus(NIDDM) patients, long duration of insulin dependent diabetic mellitus(IDDM) patients showed remarkable decrease of plantar causalgic pain: however, pain decreased unremarkably. 3. The general treatment of diabetic patients was the control of blood glucose level; however it seemed to be no effect on the degree of subjective symptom. When patients were treated with acupuncture, followed by electropucture, on Palpung(八風), Taechung(太衝:Liv3), Chok-imup(足臨泣: Gb41), Hyonjong(縣鐘 : G39), Sungsan(承山 : B57), Chok-Samni(足三里 : S36), and Yangnungchon(陽陵泉 : G34) showed a great effect on decreasing the pain.

• Clinical and Experimental Pediatrics
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• v.45 no.12
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• pp.1512-1518
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• 2002

Purpose : Twins have a higher mortality and morbidity than singletons. Co-twin with one fetal death is particularly at risk. We investigated the neonatal outcome of live co-twins when one fetus had died after the 20th gestational week, and associated risk factors. Methods : A retrospective study was performed in fifteen cases of twin pregnancy with single intrauterine fetal deaths after the 20th gestational week during the period from January 1996 to December 2000 at Chonnam University Hospital. Results : Gestational age was $33.7{\pm}3.2weeks$, birth weight was $1,992{\pm}592g$. Interval between one fetal death being detected and the delivery of a live co-twin was $32.4{\pm}29.5days$. There were 11 cases(73.3%) of premature babies less than 37 gestational weeks. Main causes of preterm delivery were preterm labor and premature rupture of membranes. Hematologic findings suggesting disseminated intravascular coagulopathy(DIC) were not found in all mothers before delivery, and was not associated with DIC and encephalomalacia of the live co-twin. Perinatal outcome of fifteen live co-twins was as follows : six were normal(40%), three were DIC(20.0%), three were encephalomalacia(20.0%), one suffered intrauterine growth retardation, there was one case of twin to twin transfusion syndrome, and one of congenital heart disease(atrial septal defect with pulmonary stenosis). The occurrence of DIC and encephalomalacia in live co-twins was not related to placental chorionicity, birth weight, gestational week, and the interval between the detection one fetal death and the delivery of a live co-twin. Conclusion : We could not find any maternal hematologic problems in twin pregnancies complicated by one fetal death. Twenty percent of live co-twins showed DIC and encephalomalacia. However, its associated risk factors were not found. We need to investigate more closely the cases of live co-twins with one intrauterine fetal death.

• Journal of Oral Medicine and Pain
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• v.38 no.4
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• pp.313-318
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• 2013

The aim of this study was to the relationship between sleep disturbances and Burning mouth syndrome(BMS). BMS presents as a chronic burning sensation in the oral mucous membrane that is frequently associated with sleep disturbances. BMS is considered neuropathic pain condition with dysfunction of small diameter afferent sensory fiber. A review of the studies reveals, BMS suggested peripheral and cental nervous system changes. Sleep disruption or Rem sleep deprivation cause an inhibition of opioid protein synthesis and a reduced affinity of ${\mu}$ and ${\delta}$ opioid receptors. Let me say that sleep disturbances suggest a risk factor For BMS and support to evaluate as a part of BMS treatment. Further study will be required to ascertain the relationship between distruption of sleep continuity or Rem sleep deprivation and BMS and the evidence of altered neurochemical degeneration of BMS.

• The Journal of Dong Guk Oriental Medicine
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• v.8 no.2
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• pp.47-67
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• 2000

The purpose of this study is to assess the usefulness of thermography in patients with musculoskeletal disease. Thermography is noninvasive, easy to reading, objective and physiologic instrument by measuring and imaging infrared energy emitted from skin surface. Thermography can show the skin temperature changes in various conditions of the body with musculoskeletal disease. This literature review was done for the usefulness of thermography in diagnosing musculoskeletal disease. In conclusion, thermography was adapted in radiculopathy, MPS, peripheral neuropathy, RSD, Raynaud's phenomen, TMJ dysfunction, etc. It was useful as a secondary diagnostic method in those diseases, also possible as a primary diagnostic method in RSD, Raynaud's phenomen. And, it might be reliable tool for estimating disease procedure and consequence after treatment. But, the objectivity of the reading and the development of the operating method are required for further adaptation in musculoskeletal disease.