• Title/Summary/Keyword: 림프종

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Usefulness of F-18 FDG PET/CT in Staging of Peripheral T Cell Lymphoma (말초성 T 세포 림프종의 병기 설정시 F-18 FDG PET/CT의 유용성)

  • Kang, Yun-Hee;Lim, Seok-Tae;Kim, Dong-Wook;Jeong, Hwan-Jeong;Sohn, Myung-Hee;Yim, Chang-Yeol
    • Nuclear Medicine and Molecular Imaging
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    • v.42 no.5
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    • pp.369-374
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    • 2008
  • Purpose: F-18 FDG PET/CT has excellent sensitivity and specificity for staging non-Hodgkin lymphomas, but to the author's knowledge few studies to date have evaluated FDG PET/CT in peripheral T cell lymphoma. We evaluated the usefulness of F-18 FDG PET/CT in staging of patients with peripheral T cell lymphoma, especially indolent cutaneous T cell lymphomas. Materials and Methods: Twenty five patients (M:F=17:8, age $53.7{\pm}14.8$ yrs) with biopsy-proven indolent cutaneous T cell (CL) or noncutaneous T cell lymphomas (NCL) underwent PET/CT scans for staging at baseline. Peak standardized uptake values (p-SUV) of all abnormal foci were measured and compared between cutaneous and noncutaneous lesions. F-18 FDG PET/CT was performed on 6 patients with indolent CL and on 19 patients with NCL. Results: All 6 patients with indolent CL had no significant FDG avidity in the skin despite histologically positive cutaneous lesions. However, FDG avidity appeared in extracutaneous lesions (lymph nodes) in two patients with CL where CT imaging suggested lymphoma involvement (mean p-SUV $4.26{\pm}0.37$ in noncutaneous lesions in CL). In NCL, FDG avidity was demonstrated in all lesions where CT imaging suggested lymphoma involvement (mean p-SUV, $8.52{\pm}5.00$ in noncutaneous lesions in NCL). Conclusion: F-18 FDG PET/CT has the limitation of usefulness for the evaluation of the skin in indolent CL. In contrast, F-18 FDG PET/CT is sensitive in staging evaluation of extracutaneous lesions regardless of CL or NCL.

Non Hodgkin lymphoma in the maxillary sinus mimicking dental abscess: a case report (치성 농양과 유사한 상악동에 발생한 비호지킨 림프종의 증례 보고)

  • Song, Ji-Young
    • Journal of Dental Rehabilitation and Applied Science
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    • v.32 no.2
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    • pp.130-134
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    • 2016
  • Malignant lymphomas are neoplasms with diffuse proliferation of neoplastic lymphocytes and their precursor cells. Diffuse large B-cell lymphoma, which is a subtype of non-Hodgkin's lymphomas, rarely occurs in the head and neck area and is especially rare in the maxillary sinus. We report a case of a 76-year-old female patient who was referred to the oral and maxillofacial surgery office for evaluation of a dental abscess as a clinical diagnosis. Laboratory tests revealed no signs of inflammation or infection; therefore, incisional biopsy was performed. The final diagnosis was diffuse large B-cell lymphoma in the maxillary sinus. Here we describe this case with a review of relevant literature.

Chemotherapy of Head & Neck Lymphoma (두경부 림프종의 화학요법)

  • Lee S.J.
    • Korean Journal of Head & Neck Oncology
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    • v.11 no.1
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    • pp.86-92
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    • 1995
  • 두경부 림프종은 두경부 림프절에 발생하는 호지킨씨병과 림프절외 림프종이 주종인 비호지킨 림프종 두종류가 있으며 이들 모두 완치율이 매우 높은 암종에 속하므로 병리학적 진단 후 정확한 병기분류를 위하여 권유되고 있는 검사들을 빠짐없이 실시하여야 된다. 조직학적 분류 및 병기가 결정된 후 내과종양의와 치료방사선의사 사이에 충분한 의 견교환을 거쳐 일차치료에 의한 근치를 유도키 위해 최선의 치료를 선택 실시함이 두경부 림프종 치료의 원칙이다.

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Fine Needle Aspiration Cytology of the Mediastinal Lesions (종격동 병변의 경흉 세침흡인 세포학적 진단)

  • Park, In-Ae;Ham, Eui-Keun
    • The Korean Journal of Cytopathology
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    • v.1 no.1
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    • pp.43-50
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    • 1990
  • The authors report 16 cases of mediastinal fine-needle aspiration cytology from Jan. 1985 to Mar. 1988 at the Seoul National University Hospital. Among them, diagnostic material were obtained in fifteen cases, establishing the diagnosis of 7 thymomas, 2 germinomas, 2 neurogenic tumosr, 1 lymphoma, and 3 meastatic carcinomas. The 9 cytologic diagnoses could be confirmed by histologic examination in 8 patients and by another cytologic method in one patient, allowing concordance rate of 77%.

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Primary Non-Hodgkin's Lymphomas of The Axilla and Arm - A Case Report - (액와부와 상완부에 발생한 원발성 비 호지킨 림프종 - 1예 보고 -)

  • Seo, Moo-Sam;Park, Han-Seong;Song, Moo-Ho;Park, Hyung-Taek;Lee, Gun-Shik
    • The Journal of the Korean bone and joint tumor society
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    • v.7 no.4
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    • pp.157-161
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    • 2001
  • Nearly a quarter of cases of non-Hodgkin's lymphoma present with extranodal, but rarely involve the soft tissue. The authors experienced one case of non-Hodgkin's lymphoma presenting as voluminous subcutaneous tissue tumors in the left axilla and arm.

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BURKITT'S LYMPHOMA OF THE MANDIBLE IN A CHILD (어린이의 하악골에서 발생한 Burkitt 림프종)

  • Lee, Soo-Eon;Sohn, Mi-Yeon;Choi, Sung-Chul;Kim, Kwang-Chul;Park, Jae-Hong
    • Journal of the korean academy of Pediatric Dentistry
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    • v.39 no.1
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    • pp.79-83
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    • 2012
  • Burkitt's lymphoma is a malignant tumor originated from B lymphocyte and a type of non-hodgkin lymphoma. It is clinically classified by endemic, sporadic and immune deficient forms. In the past, it had poor prognosis but in recent years survival rate is 50~80% treated by intensive chemotherapeutic regimens. Mostly it is a lesion of the jaws. Clinical symptoms are severe tooth mobility, displacement, gingival redness and swelling. This case is about a patient with aggressively progressing Burkitt's lymphoma of the jaws. Initial diagnosis was done in dental hospital and it has shown satisfactory outcome by prompt and appropriate treatment.

Typical and Atypical Imaging Features of Malignant Lymphoma in the Abdomen and Mimicking Diseases (복부 악성 림프종의 영상 소견 및 비슷한 소견을 보일 수 있는 질병들)

  • Jong Eun Kim;So Hyun Park;Young Sup Shim;Sungjin Yoon
    • Journal of the Korean Society of Radiology
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    • v.84 no.6
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    • pp.1266-1289
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    • 2023
  • Malignant lymphoma typically presents with homogeneous enhancement of enlarged lymph nodes without internal necrotic or cystic changes on multiphasic CT, which can be suspected without invasive diagnostic methods. However, some subtypes of malignant lymphoma show atypical imaging features, which makes diagnosis challenging for radiologists. Moreover, there are several lymphoma-mimicking diseases in current clinical practice, including leukemia, viral infections in immunocompromised patients, and primary or metastatic cancer. The ability of diagnostic processes to distinguish malignant lymphoma from mimicking diseases is necessary to establish effective management strategies for initial radiological examinations. Therefore, this study aimed to discuss the typical and atypical imaging features of malignant lymphoma as well as mimicking diseases and discuss important diagnostic clues that can help narrow down the differential diagnosis.

The Synchronous Occurrence of Splenic Marginal Zone Lymphoma in a Patient with Early Gastric Cancer: A Case Report (조기 위암과 동반된 비장 변연부 림프종 1예)

  • Park, Hyo-Jun;Kim, Keung-Mi;Choi, Min-Gew;Noh, Jae-Hyung;Sohn, Tae-Sung;Bae, Jae-Moon;Kim, Sung
    • Journal of Gastric Cancer
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    • v.9 no.2
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    • pp.63-67
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    • 2009
  • Splenic marginal zone lymphoma (SMZL) is a rare type of non-Hodgkin's lymphoma (NHL). We report here on a patient who displayed the synchronous occurrence of SMZL and early gastric cancer (EGC). The patient was a 74 year-old male with liver cirrhosis. An EGC in the gastric antrum was diagnosed and the preoperative abdomen computed tomography scan revealed splenomegaly and intra-abdominal lymphadenopathy. We performed subtotal gastrectomy and the postoperative pathologic examination revealed adenocarcinoma limited to the gastric mucosa and SMZL in the lymph nodes. The patient recovered from the surgery without complications and is now awaiting chemotherapy. SMZL has an indolent clinical course with good long-term survival and so there is the possibility of the occurrence of a second primary malignancy. Rare cases of a second primary malignancy being diagnosed along with SMZL have been described in the literature. Patients with SMZL should be carefully followed after treatment to detect the possible occurance of a second primary malignancy.

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Diffuse Large B-Cell Lymphoma in the Portal Vein (간문맥에서 생긴 미만성 거대 B세포 림프종)

  • Hyun Ji Lim;Mi-Suk Park;Yeo-Eun Kim
    • Journal of the Korean Society of Radiology
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    • v.81 no.3
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    • pp.707-713
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    • 2020
  • Tumor thrombus in the portal vein without any liver parenchymal abnormality is extremely rare. In the liver, the primary tumor most frequently presenting with intravascular tumor thrombi is hepatocellular carcinoma and lymphoma is rarely considered. Even though thrombosis occurs quite often in lymphoma, cases of tumor thrombus are rare and cases of tumor thrombus in the portal vein are even rarer. Only four cases of lymphoma with portal vein tumor thrombosis have been reported to date and all cases were the result of direct extensions of a dominant nodal or extra-nodal mass. To our knowledge, there has been no report on diffuse large B-cell lymphoma (DLBCL) presenting only within the lumen of the portal vein and not intravascular B-cell lymphoma. We present the first case of DLBCL presenting only within the lumen of the portal vein in an immunocompetent patient.

Detection of Canine Lymphoma by the Amplification of Antigen Receptor Gene Rearrangements (재배열 항원 수용체 유전자 증폭을 통한 개 림프종의 진단)

  • Yu, Do-Hyeon;Li, Ying-Hua;Lee, Jong-Hyun;Noh, Dong-Ho;Song, Ru-Hui;Lee, Mi-Jin;Choi, Ul-Soo;Park, Jin-Ho
    • Journal of Veterinary Clinics
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    • v.26 no.5
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    • pp.419-422
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    • 2009
  • We performed the PARR (PCR to detect antigen receptor rearrangements) test on DNA isolated from twelve archival canine cytological slides including nine lymphoma, two reactive lymphocytes and one sample from Ehrlichia canis infected dog. As a result, our PCR control gene, $C{\mu}$, was successfully amplified from all of the DNA samples. Six out of nine lymphoma samples showed a clonal rearrangement of immunoglobulin gene whereas three samples did a clonal rearrangement of T cell receptor gamma ($TCR{\gamma}$) gene. However, we observed no visible or clear bands from PCR conducted using our antigen receptor rearrangement primers on DNA from a reactive lymphoid cell proliferation used as a negative control. False-positive amplification in $TCR{\gamma}$ gene was observed only in one sample from E. canis infection. The use of archival cytological specimens demonstrated in this study offers potential advantages for cost-effective specimen acquisition and efficient high-fidelity DNA analysis.