• Title/Summary/Keyword: 동적진단

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A Refined Method for Quantification of Myocardial Blood Flow using N-13 Ammonia and Dynamic PET (N-13 암모니아와 양전자방출단층촬영 동적영상을 이용하여 심근혈류량을 정량화하는 새로운 방법 개발에 관한 연구)

  • Kim, Joon-Young;Lee, Kyung-Han;Kim, Sang-Eun;Choe, Yearn-Seong;Ju, Hee-Kyung;Kim, Yong-Jin;Kim, Byung-Tae;Choi, Yong
    • The Korean Journal of Nuclear Medicine
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    • v.31 no.1
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    • pp.73-82
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    • 1997
  • Regional myocardial blood flow (rMBF) can be noninvasively quantified using N-13 ammonia and dynamic positron emission tomography (PET). The quantitative accuracy of the rMBF values, however, is affected by the distortion of myocardial PET images caused by finite PET image resolution and cardiac motion. Although different methods have been developed to correct the distortion typically classified as partial volume effect and spillover, the methods are too complex to employ in a routine clinical environment. We have developed a refined method incorporating a geometric model of the volume representation of a region-of-interest (ROI) into the two-compartment N-13 ammonia model. In the refined model, partial volume effect and spillover are conveniently corrected by an additional parameter in the mathematical model. To examine the accuracy of this approach, studies were performed in 9 coronary artery disease patients. Dynamic transaxial images (16 frames) were acquired with a GE $Advance^{TM}$ PET scanner simultaneous with intravenous injection of 20 mCi N-13 ammonia. rMBF was examined at rest and during pharmacologically (dipyridamole) induced coronary hyperemia. Three sectorial myocardium (septum, anterior wall and lateral wall) and blood pool time-activity curves were generated using dynamic images from manually drawn ROIs. The accuracy of rMBF values estimated by the refined method was examined by comparing to the values estimated using the conventional two-compartment model without partial volume effect correction rMBF values obtained by the refined method linearly correlated with rMBF values obtained by the conventional method (108 myocardial segments, correlation coefficient (r)=0.88). Additionally, underestimated rMBF values by the conventional method due to partial volume effect were corrected by theoretically predicted amount in the refined method (slope(m)=1.57). Spillover fraction estimated by the two methods agreed well (r=1.00, m=0.98). In conclusion, accurate rMBF values can be efficiently quantified by the refined method incorporating myocardium geometric information into the two-compartment model using N-13 ammonia and PET.

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Evaluation of K-Cabbage Model for Yield Prediction of Chinese Cabbage in Highland Areas (고랭지 배추 생산 예측을 위한 K-배추 모델 평가)

  • Seong Eun Lee;Hyun Hee Han;Kyung Hwan Moon;Dae Hyun Kim;Byung-Hyuk Kim;Sang Gyu Lee;Hee Ju Lee;Suhyun Ryu;Hyerim Lee;Joon Yong Shim;Yong Soon Shin;Mun Il Ahn;Hee Ae Lee
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.25 no.4
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    • pp.398-403
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    • 2023
  • Process-based K-cabbage model is based on physiological processes such as photosynthesis and phenology, making it possible to predict crop growth under different climate conditions that have never been experienced before. Current first-stage process-based models can be used to assess climate impact through yield prediction based on climate change scenarios, but no comparison has been performed between big data obtained from the main production area and model prediction so far. The aim of this study was to find out the direction of model improvement when using the current model for yield prediction. For this purpose, model performance evaluation was conducted based on data collected from farmers growing 'Chungwang' cabbage in Taebaek and Samcheok, the main producing areas of Chinese cabbage in highland region. The farms surveyed in this study had different cultivation methods in terms of planting date and soil water and nutrient management. The results showed that the potential biomass estimated using the K-cabbage model exceeded the observed values in all cases. Although predictions and observations at the time of harvest did not show a complete positive correlation due to limitations caused by the use of fresh weight in the model evaluation process (R2=0.74, RMSE=866.4), when fitting the model based on the values 2 weeks before harvest, the growth suitability index was different for each farm. These results are suggested to be due to differences in soil properties and management practices between farms. Therefore, to predict attainable yields taking into account differences in soil and management practices between farms, it is necessary to integrate dynamic soil nutrient and moisture modules into crop models, rather than using arbitrary growth suitability indices in current K-cabbage model.

Research on The Utility of Acquisition of Oblique Views of Bilateral Orbit During the Dacryoscintigraphy (눈물길 조영검사 시 양측 안 와 사위 상 획득의 유용성에 대한 연구)

  • Park, Jwa-Woo;Lee, Bum-Hee;Park, Seung-Hwan;Park, Su-Young;Jung, Chan-Wook;Ryu, Hyung-Gi;Kim, Ho-Shin
    • The Korean Journal of Nuclear Medicine Technology
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    • v.18 no.1
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    • pp.76-81
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    • 2014
  • Purpose: Diversity and the lachrymal duct deformities and the passage inside the nasal cavity except for anterior image such as epiphora happens during the test were able to express more precisely during the dacryoscintigraphy. Also, we thought about the necessity of a method to classify the passage into the naso-lachrymal duct from epiphora. Therefore, we are to find the validity of the method to obtain both oblique views except for anterior views. Materials and Methods: The targets of this research are 78 patients with epiphora due to the blockage at the lachrymal duct from January 2013 to August 2013. Average age was $56.96{\pm}13.36$. By using a micropipette, we dropped 1-2 drops of $^{99m}TcO4^-$ of 3.7 MBq (0.1 mCi) with $10{\mu}L$ of each drop into the inferior conjunctival fold, then we performed dynamic check for 20 minutes with 20 frames of each minute. In case of we checked the passage from both eyes to nasal cavity immediately after the dynamic check, we obtained oblique view immediately. If we didn't see the passage in either side of the orbit, we obtained oblique views of the orbit after checking the frontal film in 40 minutes. The instrument we used was Pin-hole Collimator with Gamma Camera(Siemens Orbiter, Hoffman Estates, IL, USA). Results: Among the 78 patients with dacryoscintigraphy, 35 patients were confirmed with passage into the nasal cavity from the anterior view. Among those 35 patients, 15 patients were confirmed with passage into the nasal cavity on both eyes, and it was able to observe better passage patterns through oblique view with a result of 8 on both eyes, 2 on left eye, and 1 on right eye. 20 patients had passage in left eye or right eye, among those patients 10 patients showed clear passage compared to the anterior view. 13 patients had possible passage, and 30 patients had no proof of motion of the tracer. To sum up, 21 patients (60%) among 35 patients showed clear pattern of passage with additional oblique views compared to anterior view. People responded obtaining oblique views though 5 points scale about the utility of passage identification helps make diagnoses the passage, passage delayed, and blockage of naso-lachrymal duct by showing the well-seen portions from anterior view. Also, when classifying passage to naso-lachrymal duct and flow to the skin, oblique views has higher chance of classification in case of epiphora (anterior:$4.14{\pm}0.3$, oblique:$4.55{\pm}0.4$). Conclusion: It is considered that if you obtain oblique views of the bilateral orbits in addition to anterior view during the dacryoscintigraphy, the ability of diagnose for reading will become higher because you will be able to see the areas that you could not observe from the anterior view so that you can see if it emitted after the naso-lachrymal duct and the flow of epiphora on the skin.

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A Survey of DEA Applications in Measuring the Efficiency Performance of Construction Organizations (비모수 분석방법에 의한 국내 건설조직 성과 측정 방향에 관한 연구 - DEA를 이용한 국내 연구 문헌 고찰을 기반으로 -)

  • Lee, Yoon-Sun
    • Korean Journal of Construction Engineering and Management
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    • v.15 no.5
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    • pp.103-114
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    • 2014
  • Data envelopment analysis (DEA) measures the relative efficiency of decision making units (DMUs) with multiple performance factors that are grouped into outputs and inputs. DEA has proven to be superior to simple aggregation of performance measures, and is also useful for evaluating the performance of construction companies for comparison with competitor performance. The purpose of this study was to survey literatures on the application of DEA methodology and to propose a methodological scheme to measure the performance of construction organizations. Articles on previous studies were surveyed and examined as part of a comprehensive review. The survey revealed that the application of DEA in the construction industry was li mited. Further, the survey indicated that there is a need for the development of a methodological framework on the special goals and subjects of performance measurement, methods of data structure and collection, selection of appropriate DEA models, analysis of results, and post-test. Based on the survey, this study identified and discussed the types of major issues and topics for future studies from a methodological perspective, which could be helpful to researchers interested in using DEA to study performance issues in construction organizations.

Effect of Aquatic Ramp Exercise on Gait And Activity Of Daily Living In Child With Spinal Muscular Atrophy Type II: Single Subject Research (수중 경사로 보행 훈련이 제2형 척수성근위축증 아동의 보행 및 일상생활동작에 미치는 효과: 개별실험연구)

  • Sung, Yun-Hee
    • Journal of rehabilitation welfare engineering & assistive technology
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    • v.10 no.2
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    • pp.107-112
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    • 2016
  • The purpose of this study was to determine the effect of aquatic ramp walking exercise on the activity of the quadriceps, gait and activity of daily living in child with Spinal Muscular Atrophy (SMA) type II. A 5 years-old girl with SMA type II participated in this study. This study used single-subject reverse(A-B-A) design study. There are 12 sessions(4weeks 3 times a week) each during the baseline phase(A), the intervention phase(B), the follow up phase(A). During the baseline phase and the follow up phase performed general aquatic therapy, the intervention phase additional performed walking activity on ramp in pool (60m). Surface electromyogram, Timed Up and Go (TUG) test, ACTIVLIM were used as outcome. During the intervention phase, there were decrease on the activity of the quadriceps. In modified TUG test, gait time reduced during the intervention phase. The ACTIVLIM logit score increased during intervention phase by comparison with the baseline phase. These findings suggest that an aquatic ramp walking exercise activities have the therapeutic possibility on the quadriceps activity and gait ability for child with SMA type II.

Physical and Ecological Characteristics of Streams: A Case of Sand-bed Rivers in a Gyeonggi Region (하천의 물리적 생태적 특성: 경기 지방 모래하천의 사례)

  • Kim, Hye-Ju;Kim, Chang-Wan;Lee, Du-Han
    • Proceedings of the Korea Water Resources Association Conference
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    • 2005.05b
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    • pp.449-453
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    • 2005
  • 하천의 물리적 생태적 특성에 대한 연구는 하천유형분류의 기초 자료로서 큰 의미가 있다. 그러나 국내의 경우 이를 위한 하천의 조사는 매우 드물며, 국부적이었다. 더욱이 이러한 생태적 물리적 특성을 근거로 한 하천 유형적 특성을 연구한 사례는 없었다. 본 연구에서는 하천의 유형을 분류하는 것은 아니지만 하천을 더욱 효율적으로 계획하고 관리하는데 필요한 기초자료를 구축하고자 하였다. 그리하여 1차적 연구로 자연환경이 유사한 하천들을 일시에 선정하여 동일한 방법으로 각 하천의 물리적 생태적 특성을 조사하고 평가하여 대상 하천의 공통적 특성을 가려내고자 하였다. 이와 관련하여 본 연구에서는 하천의 물리적 구조조사법을 유럽공동체에서 사용하는 기준과 방법에 따라 시범적으로 실시하여 국내하천의 하천환경조사를 위한 적용성 여부도 진단하고자 하였다. 하천의 물리적 구조등급이란 하천의 공간적 환경과 저수로 하상재료의 물리적 차이를 의미하는 것으로 하천 자체는 물론 하천범람지에 영향을 주는 생태적 기능의 수리 특성, 하천의 물리 특성, 수생태 특성 등을 포괄하게 된다. 따라서 하천의 물리적 구조등급은 하천구조의 생태적 질과 하천구조로 나타나게 되는 동적 과정(dynamic process)의 질을 평가하는 척도가 될 수 있다. 본 연구에서는 남한강수계의 청미천, 양화천, 복하천을 대상으로 물리적 구조조사법과 식생조사를 병행하였으며 이로부터 하천의 물리적 구조등급이 수질등급과 정량적이지는 않지만 전반적인 하천의 생태성 또는 자연도를 가늠할 수 있는 하나의 지료로 활용할 수 있음을 알 수 있었다.양토를 기준으로 할 때 강우량과 침투수의 관계는 $I_{10}(mm)=0.44R(mm)+5.8(r^2=0.55)$이었다. y절이 발생한 이유는 이전 강우에 의해 침투되고 있는 물이 있음을 함축하며 기울기 0.40은 강우의 $40\%$가 지하로 침투하였음을 의미한다. 침투수량은 토성별로 양토를 1.0으로 기준할 때 사양토가 1.12로 가장 컸고, 식양토 0.94, 식토 0.91로 평가되었다. 이는 토성간의 침투속도 및 투수속도의 경향이 반영된 것이다. 경사에 따라서는 경사도가 증가할수록 지수적으로 감소하였으며 $10\% 경사일 때를 기준으로 $I(mm)=I_{10}{\times}1.17{\times}e^{-0.0164s(\%)}$로 나타났다. 같은 조건에서 강우량과 유거수의 관계는 $Ro_{10}(mm)=5.32e^{0.11R(mm)}(r^2=0.69)$로 나타났다. 이는 토양의 투수특성에 따라 강우량 증가에 비례하여 점증하는 침투수와 구분되는 현상이었다. 경사와 토양이 같은 조건에서 나지의 경우 역시 $Ro_{B10}(mm)=20.3e^{0.08R(mm)(r^2=0.84)$로 지수적으로 증가하는 경향을 나타내었다. 유거수량은 토성별로 양토를 1.0으로 기준할 때 사양토가 0.86으로 가장 작았고, 식양토 1.09, 식토 1.15로 평가되어 침투수에 비해 토성별 차이가 크게 나타났다. 이는 토성이 세립질일 수록 유거수의 저항이 작기 때문으로 생각된다. 경사에 따라서는 경사

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Assessment of Isokinetic Muscle Function, Balance and Flexibility in Elite High School Kayakers (고등학교 엘리트 카약 선수들의 등속성 근기능·균형성·유연성 측정 및 평가)

  • Shin, Kwang-Taek;Sohn, Jee-Hoon
    • Journal of Digital Convergence
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    • v.16 no.6
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    • pp.407-416
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    • 2018
  • The purpose of this study is to evaluate elite high school kayaker's iso-kinetic muscle function and provide physical training advices. Biodex system IV, Biodex stabilizer system, Inbody 3.0 and CNP-5403 are used to investigate 11 kayaker's muscle function(peak torque, average power and work fatigue), dynamic balance, body compositions, and flexibility. S4, S5, S8, S10, S11 are needed to train shoulder muscle strength and power. S5, S6, S10, S11 are needed to strengthen shoulder muscle endurance. S5, S7, S8, S10, S11 are needed to train knee muscle strength and power. S1, S4, S5, S10 are needed to strengthen knee muscle endurance. S3, S10, S11 are needed to train wrist muscle endurance. Based on these results we should establish an muscle function enhancing program with periodic inspection for elite kayakers. And standardized training program should be sublated.

Effects of Task-Oriented programme on Balance and Upper Extremity in stroke (과제 지향적 프로그램이 뇌졸중환자의 균형과 상지기능에 미치는 효과: 단일사례연구)

  • Kim, Eun-Joo;Hong, So-Young;Kim, Kyeong-Mi
    • Therapeutic Science for Rehabilitation
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    • v.1 no.1
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    • pp.17-28
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    • 2012
  • Objective : The purpose of this study is to assess effects of task oriented programme on balance and upper extremity function in stroke patient. Methods : The subject is right hemiplegia with stroke and participated for 6 weeks. The design of study ABA designed of single subject research. The baseline phase consisted of 5 sessions. The intervention phase consisted of 15 sessions and performed task oriented training. The Maintenance phase consisted of 5 sessions. An assessment of upper extremity function was made using a Manual Function Test(MFT) and balance were assessed by the Time Up and Go test(TUG), Nintendo Wii Balance Board Test. Results : Dynamic balance improved from 51.53 to 42.62. At baseline, difference between left and right of the static balance was an average of 13.8, After treatment, the static balance difference was 6.29 and It was closer to zero than baseline, so static balance has been stable feature. Also, MFT point increased from 6 to 7.6. Conclusion : Task oriented programme can useful in balance and upper extremity function in stroke patient. Further studies need to generalize these findings.

A Hippocampus Segmentation in Brain MR Images using Level-Set Method (레벨 셋 방법을 이용한 뇌 MR 영상에서 해마영역 분할)

  • Lee, Young-Seung;Choi, Heung-Kook
    • Journal of Korea Multimedia Society
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    • v.15 no.9
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    • pp.1075-1085
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    • 2012
  • In clinical research using medical images, the image segmentation is one of the most important processes. Especially, the hippocampal atrophy is helpful for the clinical Alzheimer diagnosis as a specific marker of the progress of Alzheimer. In order to measure hippocampus volume exactly, segmentation of the hippocampus is essential. However, the hippocampus has some features like relatively low contrast, low signal-to-noise ratio, discreted boundary in MRI images, and these features make it difficult to segment hippocampus. To solve this problem, firstly, We selected region of interest from an experiment image, subtracted a original image from the negative image of the original image, enhanced contrast, and applied anisotropic diffusion filtering and gaussian filtering as preprocessing. Finally, We performed an image segmentation using two level set methods. Through a variety of approaches for the validation of proposed hippocampus segmentation method, We confirmed that our proposed method improved the rate and accuracy of the segmentation. Consequently, the proposed method is suitable for segmentation of the area which has similar features with the hippocampus. We believe that our method has great potential if successfully combined with other research findings.

남녀(男女)의 차이(差異)에 근거(根據)한 남녀형상(男女形象)의 의학적(醫學的) 운용(運用)에 대한 연구(硏究)

  • Lee, In-Su;Yun, Chang-Ryeol
    • Journal of Korean Medical classics
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    • v.19 no.1 s.32
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    • pp.47-109
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    • 2006
  • 서양의학상인위남녀근근시재생식기부동적인(西洋醫學上認爲男女僅僅是在生殖器不同的人). 최근(最近), Legato, Marianne J.박사창립료(博士創立了)‘성인지의학(性認知醫學)’학(學), 개시인식도남녀적차이(開始認識到男女的差異), 주장남녀재치료방법상역부동법(主張男女在治療方法上亦不同法), 종이저일연구진입도료신적단계(從而這一硏究進入到了新的段階). 단시한의학종(但是韓醫學從)${\ulcorner}$황제내경(黃帝內經)${\lrcorner}$개시(開始), 취인위남녀재구조상유근본적차이(就認爲男女在構造上有根本的差異), 이차재생리(而且在生理), 병리(病理), 진단(診斷), 치료상야부동(治療上也不同). 기록한의학기본원리적주역적상관서적화(記錄韓醫學基本原理的周易的相關書籍和)${\ulcorner}$황제내경(黃帝內經)${\lrcorner}$, 이급역대적주요한의서적급종사임상적한의사적서적상(以及歷代的主要韓醫書籍及從事臨床的韓醫師的書籍上), 역도인위남녀유차이(亦都認爲男女有差異). 관어남녀적생성(關於男女的生成), 재(在)${\ulcorner}$보제방(普濟方) 방맥총론(方脈總論)${\lrcorner}$적변남녀형생신육론중제출료(的辨男女形生神毓論中提出了男女的形成有異). ${\ulcorner}$동의보감(東醫寶鑑)${\lrcorner}$여기타한의서부동(與其他韓醫書不同), 불시이질병위주(不是以疾病爲主), 이시이신위중심(而是以身爲中心), 즉목차안형상진행료배열(卽目次按形象進行了排列), 차상세지언급료남녀(且詳細地言及了男女). 나요남녀시고정불변적마 불시적(不是的). ${\ulcorner}$동의보감(東醫寶鑑) 신형장부론(身形臟腑論)${\lrcorner}$인위(認爲)‘인적형색유차이(人的形色有差異), 장부이유이(臟腑易有異), 고외증수동(故外症雖同), 치법인인이이(治法因人而異).’ 안형상선용부동적치법적관점(按形象選用不同的治法的觀点), 이통과주단계지언이표명(已通過朱丹溪之言而表明). 불변관점상여자체격소이동(不變觀点上女子體格小易動), 남자체격대이와(男子體格大易臥). 남자속양기이산(男子屬陽氣易散). 여남자정서초차(如男子情緖稍差), 즉음주해수(卽飮酒解愁), 불이득우울증(不易得憂鬱症). 응보기정기(應補其精氣). 여자속음기이울체(女子屬陰氣易鬱滯), 다유인기지성질(多有忍氣之性質), 이득우울증(易得憂鬱症), 고다용산기약(故多用散氣藥). 간단이언(簡單而言)‘남자위병허증(男子爲病虛證), 여자위병실증(女子爲病實證).’ 종변화적관점래용약(從變化的觀点來用藥), 예여남자수소가용여자약적사물탕(例如男子瘦小可用女子藥的四物湯). 여자비가용남자약적사군자탕(女子肥可用男子藥的四君子湯). 여자골장가용남자약적육미지황환(女子骨壯可用男子藥的六味地黃丸). 위료갱용역이해(爲了更容易理解)‘남녀불변화변화적관점재의학적운용(男女不變和變化的觀点在醫學的運用)’, 이임상병례진행설명(以臨床病例進行說明). 재임상상통과형색맥증적합일화변증론치결정처방(在臨床上通過形色脈證的合一和辨證論治決定處方). 즉불능단순적인위(卽不能單純的認爲), 인위시남자취용육미지황환(因爲是男子就用六味地黃丸), 여자취용사물탕(女子就用四物湯). 남자약소가용사군자탕(男子若小可用四君子湯) 사물탕(四物湯) 육미지황탕(六味地黃湯), 이여자약대가용사군자탕(而女子若大可用四君子湯) 이진탕(二陳湯) 평위산(平胃散) 육군자탕(六君子湯). 인차(因此) 남녀재구조(男女在構造) 생리(生理) 병리유근본성차이(病理有根本性差異), 불이형상래구분(不以形象來區分), 용약상시지불변적입장(用藥上是持不變的立場), 이이형상용약(而以形象用藥), 시종변화적입장래고려적(是從變化的立場來考慮的). 인위이남녀위기준종사임상(認爲以男女爲基準從事臨床), 시부합한의학기본원리지음양관(是符合韓醫學基本原理之陰陽觀).

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