• Journal of Acupuncture Research
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• v.27 no.5
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• pp.105-115
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• 2010

목적 : 침은 다양한 질환의 치료에 보편적으로 쓰이고 있으며 고혈압, 당뇨, 정신질환 등을 포함한 스트레스성 질환에도 활용되고 있다. 결박 스트레스는 스트레스 호르몬(코르티코스테론, 멜라토닌)의 혈장 농도를 크게 증가시키는 간단하고 효과적인 스트레스 요인이다. 본 연구는 결박 스트레스를 시행한 백서의 스트레스 호르몬의 혈중 농도에 대한 전기침의 효과를 조사하였다. 방법 : 결박 그룹은 2시간의 결박 스트레스를 받았으며 결박 스트레스 및 고주파수 전침그룹과 결박 스트레스 및 저주파수 전침그룹은 결박 스트레스와 고주파수 전침, 또는 결박 스트레스와 저주파수 전침을 동시에 각각 시행하였다. 급성 스트레스 유발 시에는 결박 스트레스를 1차례, 만성 스트레스 유발 시에는 7차례 시행하였다. 전기침 자극에는 우측 족삼리($ST_{36}$)를 사용하였다. 결박 스트레스 및 전기침으로 유도된 코르티코스테론과 멜라토닌의 농도를 측정하기 위해서 결박 스트레스 및 전기침 자극이 시작된 30분, 60분, 90분, 120분 후에 백서를 단두하여 혈액 샘플을 채취하였다. 결과 : 급성 스트레스 유발 시에는 고주파수 전침그룹의 코르티코스테론 혈장 농도가 증가하였고 멜라토닌 농도의 시간적 패턴을 변화시켰으나 저주파수 전침그룹에서는 유의한 변화가 없었다. 만성 스트레스 유발 시에는 고주파수 전침그룹의 혈장 코르티코스테론과 멜라토닌 농도가 유의하게 감소되었으나 저주파수 전침그룹에서는 변화가 없었다. 결론 : 이러한 결과는 전침이 결박 스트레스로 유도된 스트레스 호르몬의 혈장 농도 및 시간적 분비패턴을 변화시키는 효과가 있으나 스트레스 호르몬 반응을 변화시키는 데 있어서 주파수에 따른 유의한 차이가 있다는 것을 의미한다.

• Journal of Digital Convergence
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• v.15 no.2
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• pp.411-419
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• 2017

This study was to investigate whether a trunk correction taping plus scapular setting exercises has an effect on trunk muscle activation and trunk balance and upper extremity function in patients with stroke. Twenty stroke patients were randomly divided into a trunk correction taping with scapular setting exercise group (n=10) and a scapular setting exercise group (n=10), and each group performed given interventions for 30 minutes for 4 weeks. In the experimental group, there were significant increases in muscle activation, K-TIS, and MFT (p<.05), and a significant improvement was detected in K-TIS and MFT compared to the control group (p<.05). This study suggests that a trunk correction taping with scapular setting exercises was more effective on trunk muscle activation, trunk balance, and upper extremity function in stroke patients compared to a scapular setting exercise. It could be clinically more significant if the change in the onset time of muscle activity is confirmed in the further researches.

• Journal of Digital Convergence
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• v.16 no.7
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• pp.511-516
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• 2018

This study examined the effectiveness of a short thumb splint and a glove type splint which combined features of a fitness glove in order to improve hand function and performance of functional task after traumatic brain injury. One subject with traumatic brain injury participated in this study and wore a short thumb splint and customized glove type splint. His hand function was significantly improved when comparing to that of not using those splints. In addition, using the glove type splint was more significant to perform functional tasks than using the short thumb splint. The findings of this study identified that hand function of people with traumatic brain injury was improved by using those splints as an occupational therapy service and it is necessary to adapt the customized splints according to the personal characteristics.

• Journal of the Korean Crystal Growth and Crystal Technology
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• v.10 no.4
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• pp.330-336
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• 2000

Effects of microstructure and indentation stress on fracture behavior of glass-infiltrated alumina composite for dental restorative application were investigated by the Hertzian and Vickers indentation method. Indentation stress-strain curve of glass-infiltrated alumina has showed the quasi-plastic behavior - deviation from linearity at high stress and the classical Hertzian cone crack, which could be confirmed the subsurface damage micrographs using bonded-interface specimen technique. The indentation stress-strain curves for the starting preforms are strongly dependent on porosity and microstructure of the preforms. On the other hand, the curves for the infiltrated composites are relatively insensitive to these factors. The failure of composite is originated at quasi-plastic deformation region. Damage and fracture behavior due to Hertzian stress field is theoretically examined, so that the indentation stress field plays a great role in material degradation. After Hertzian indentation annealing processing changes fracture behavior of alumina composite, so that stress field in material is healed through annealing.

• Journal of Sasang Constitutional Medicine
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• v.13 no.1
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• pp.61-69
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• 2001

사상의학적 견지에서 태음인(太陰人)의 중풍, 치매와 같은 신경계질환에 다용되고 있는 열다한소탕(熱多寒少湯)은 최근에 그 임상적 효과를 뒷받침할 다각적인 연구들이 이루어지고 있음에도 불구하고 그 정확한 약리학적 기전에 대해서는 밝혀지지 않고 있다. 본 연구에서는 인간성상세포를 이용하여 열다한소탕(熱多寒少湯)이 substance P (SP)와 lipopolysaccharide (LPS)에 의해 유도되는 다양한 세포활성물질의 분비량의 조절을 검토함으로써 열다한소탕(熱多寒少湯)의 약리기전을 면역학적 측면에서 보다 세밀하게 살펴보고자 하였다. 열다한소탕(熱多寒少湯) 수침액은 인간 뇌 성상세포로 부터 LPS와 SP의 동시자극에 의해 생성되는 세포활성물질중 interleukin (IL)-1, IL-4, IL-6 및 tumor necrosisfaccor-${\alpha}$ (TNF-${\alpha}$)의 분비를 농도의존적으로 억제했다. 그러나 interferon-${\gamma}$ (IFN-${\gamma}$) 및 IL-2의 분비 조절에는 영향을 미치지 않았다. 그리고 항 IL-$1{\beta}$ 항체에 의해 SP 유도성 TNF-${\alpha}$ 분비의 증가가 억제되기 때문에 IL-1은 TNF-${\alpha}$ 증가를 매개하는 역할을 하는 것으로 사료된다. 이상의 결과는 열다한소탕(熱多寒少湯)에 의한 급성기 중풍환자 치료 효과가 뇌 성상세포로부터 분비되는 세포활성물질의 조절과 밀접한 관련성이 있다는 것을 암시하고 있다.

• Journal of Genetic Medicine
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• v.7 no.1
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• pp.24-36
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• 2010

Colorectal cancer is one of the most steeply increasing malignancies in Korea. Among 398,824 new patients recorded by the Korea Central Cancer Registry between 2003 and 2005, 47,915 cases involved colorectal cancers, accounting for 12.0 % of all malignancies. In 2002, total number of colorectal cancer cases had accounted for 11.2 % of all malignancies. Hereditary syndromes are the source of approximately 5% to 15% of overall colorectal cancer cases. Hereditary colorectal cancers are divided into two types: hereditary nonpolyposis colorectal cancer (HNPCC), and cancers associated with hereditary colorectal polyposis, including familial adenomatous polyposis (FAP), Peutz-Jeghers syndrome, juvenile polyposis, and the recently reported hMutYH (MYH)-associated polyposis (MAP). Hereditary colorectal cancers have unique clinical features distinct from sporadic cancer because these are due to germline mutations of the causative genes; (i) early age-of-onset of cancer, (ii) frequent association with synchronous or metachronous tumors, (iii) frequent association with extracolonic manifestations. The management strategy for patients with hereditary colorectal cancer is quite different from that for sporadic cancer. Furthermore, screening, genetic counseling, and surveillance for at-risk familial member are also important. A well-organized registry can plays a central role in the surveillance and management of families affected by hereditary colorectal cancers. Here, we discuss each type of hereditary colorectal cancer, focusing on the clinical and genetic characteristics, management, genetic screening, and surveillance.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.8 no.2
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• pp.420-429
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• 2004

It has been needed diagnosis technology of the EFG(Electro Functio Gram) measurement concept which is incorporated characteristic of modern science and biomedical engineering, because function abnormality diagnosis can't diagnose with visualization instruments or clinical pathology. The general diagnosis system(EFG system) has been developed to use basic diagnosis instrument that has reappearance, reliance and convenience using the functio diagnosis technology, in the field of western/oriental medicine. Also, we improved sticking electrode and simultaneous measurement method of the limbs 8CH, head 2CH to diagnose body circulation of Qi and acupoints for Oriental Medicine diagnosis/therapy. The result of clinical for adult man 20 persons, the EFG system can diagnose state of 12 meridians and autonomic nervous system. Therefore, in this paper, we designed of oriental medicine diagnosis system by bio-electric response with materialized H/W and S/W for 12 meridians state diagnosis of human body and system construction of the EFG.

• Journal of radiological science and technology
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• v.28 no.1
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• pp.9-12
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• 2005

In this study, film type radiation sensor tips are fabricated for remote sensing of X or g-ray with inorganic scintillators and plastic optical fiber. The visible range of light from the inorganic scintillator that is generated by X and g-ray is guided by the plastic optical fiber and is measured by optical detector and power-meter. It is expected that the fiber-optic radiation sensor which is possible to be developed based on this study is used for remote, fast and exact sensing of X or g-ray because of its characteristics such as very small size, light weight and no interference to electromagnetic fields.

• Journal of Chest Surgery
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• v.38 no.6 s.251
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• pp.434-437
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• 2005

Since the operative mortality rate of the Acute aortic dissection has been reducing, a more extensive primary repair of the dissected aorta is preferred for acute aortic dissection to reduce the needs of secondary procedures. We performed a total aortic arch replacement with distal stent-grafting in acute type A aortic dissection. The patient was a 50-years old man. He recovered from the operation and was followed up for 7 months. The pseudolumen in the descending aorta was obliterated with the stent.

• Journal of Chest Surgery
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• v.39 no.4 s.261
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• pp.335-339
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• 2006

Benign metastasizing leiomyoma (BML) is a rare entity, characterized by the occurrence of multiple smooth muscle nodules in the lung with histologically benign leiomyoma, Both the uterine and pulmonary tumors have been found to express estrogen and progesterone receptors, which suggest that the pulmonary lesions represented metastases from leiomyoma. We experienced a 41-year-old female patient with BML and report here with the literature review.