• Title/Summary/Keyword: 동시치료

Search Result 1,159, Processing Time 0.032 seconds

Concurrent Validity of the Self-Report and Proxy-Report Versions of a Health-Related Quality of Life Measure: A Focus Group Study (초등학교 아동과 보호자에게 적용한 삶의 질 평가도구의 동시타당도 연구: 표적집단 파일럿연구)

  • Choi, Bongsam
    • The Journal of Korean Academy of Sensory Integration
    • /
    • v.21 no.2
    • /
    • pp.45-57
    • /
    • 2023
  • Objective : The purpose of this study was to investigate the concurrent validity of the self- and proxy-report versions of the KIDSCREEN-10 quality of life questionnaire. Methods : A total of nine children and nine parents were selected to represent a cohort registered for a school-based wellness program. Two versions of the KIDSCREEN-10 questionnaire (self- and proxy reports) were administered to the children and their parents. The Rasch rating scale model was applied to determine the dimensionality and item difficulty of the two versions of the questionnaire. Moreover, the item-person matching map and Spearman's rho were compared to confirm the concurrent validity of the two versions. Results : All items, except four items (i.e., autonomy, home life, concentration/learning, and peers/social support), fit the Rasch rating scale model of the children's self-report version of the questionnaire. With regard to the parent's proxy-report version, two items misfit the model. While the items of the self- and proxy-report versions showed similar item difficulties, the parents had a tendency to be more severe in their ratings than the children. The correlation between the two versions was relatively low (Spearman's rho = .533, p > .05). The scatterplots between the two versions showed differences in the item difficulties of the physical and psychological well-being and self-perception items. Conclusion : These findings suggest that the three identified items should be taken into consideration when measuring children's health-related quality of life using the KIDSCREEN-10 questionnaire.

The Role of Primary Radiotherapy for Squamous Cell Carcinoma of the Suprag1ottic Larynx (성문상부 상피세포암에서의 근치적 방사선치료의 역할)

  • Kim, Won-Taek;Kim, Dong-Won;Kwon, Byung-Hyun;Nam, Ji-Ho;Hur, Won-Joo
    • Radiation Oncology Journal
    • /
    • v.18 no.4
    • /
    • pp.233-243
    • /
    • 2000
  • Purpose : First of all, this study was performed to assess the result of curative radiotherapy and to evaluate different possible prognostic factors for squamous cell carcinoma of the supraglottic larynx treated at the Pusan National University Hospital. The second goal of this study was by comparing our data with those of other study groups, to determine the better treatment policy of supraglottic cancer in future. Methods and Material : Thirty-two patients with squamous cell carcinoma of the supraglottic larynx were treated with radiotherapy at Pusan National University Hospital, from August 1985 to December 1996. Minimum follow-up period was 29 months, Twenty-seven patients (84.4$\%$) were followed up over 5 years. Radiotherapy was delivered with 6 MV photons to the primary laryngeal tumor and regional iymphatics with shrinking field technique. Ail patients received radiotherapy under conventional fractionated schedule (once a day). Median total tumor dose was 70.2 Gy (range, 55.8 to 75.6 Gy) on primary or gross tumor lesion. Thirteen patients had Induction chemotherapy with cisplatln and 5-fluorouracil (1-3 cycles). Patient distribution, according to the different stages, were as follows: stage I, 5/32 (15.6$\%$): stage II, 10/32 (31.3$\%$); stage III, 8/32 (25$\%$): stage IV, 9/32 (28.1$\%$). Results :The 5-year overall survival rate of the whole series (32 patients) was 51.7$\%$. The overall survival rate at 5-years was 80$\%$ in stage I, 66.7$\%$ in stage II, 42.9$\%$ in stage III, 25$\%$ in stage IV (p=0.0958). The S-year local control rates after radiotherapy were as fellows: stage I, 100$\%$; stage II, 60$\%$ stage III, 62.5$\%$; stage IV, 44.4$\%$ (p=0.233). Overall vocal preservation rates was 65.6$\%$, 100% In stage I, 70% in stage II, 62.5$\%$ In stage III, 44.4$\%$ in stage IV (p=0.210). There was no statistical significance in survival and local control rate between neoadjuvant chemotherapy followed by radiotherapy group and radiotherapy alone group. Severe laryngeal edema was found in 2 cases after radiotllerapy, emergent tracheostomy was done. Four patients were died from distant metastsis, . three in lung, one in brain. Double primary tumor was found in 2 cases, one in lung (metachronous), another in thyroid (synchronous). Ulcerative lesions were revealed as unfavorable prognostic factor ( p=0.0215), and radiation dose (more or less than 70.2 Gy) was an important factor on survival (p=0.002). Conclusion : The role of radiotherapy treatment of supraglottic carcinoma is to important factor on survival and to preserve the laryngeal function. Based on our data and other studies, early and moderately advanced supragiottic carcinomas could be successfully treated with either consewative surgery or radiotherapy alone. Both modalities showed similar results in survival and vocal preservation. For the advanced cases, radiotherapy alone is Inadequate for curative aim and surgery combined with radiotherapy should be done in operable patients. When patients refuse operation or want to preserve vocal function, or for the patients with inoperable medical conditions, combined chemoradiotherapy (concurrent) or altered fractionated radiotherapy with or without radiosensitizer should be taken into consideration in future.

  • PDF

A Study on Portable Multi Electrical Cupping System (휴대용 멀티 전동 부항 시스템에 관한 연구)

  • Kim, Jong-Chan;Yang, Chul-Oh;Ban, Kyeong-Jin;Lee, Kwang-Eui;Kim, Chee-Yong
    • Journal of Korea Multimedia Society
    • /
    • v.15 no.2
    • /
    • pp.250-257
    • /
    • 2012
  • Recently oriental medicine has become a new issue in the global medical field because of increasing demands for the treatment of old people. Western medical equipment is becoming popular with big companies related to IT, communication and medical treatment. But globalization of oriental medicine techniques is inadequate due to lack of knowledge about oriental medicine. The cupping equipment has great growth potential because it is easy for old people to use the equipment. The purpose of this paper is to promote the portable multi electrical cupping system. The system may be used by patients themselves without any help from others. By using many cupping cups at the same time and regulating the timer and vacuum pressure. The patient can decrease itching and relax the hardened muscles. The system is expected to grow in the future as oriental medicine will be in high demand in aging society with IT convergence industry.

Analysis on Operation of Anti-Virus Systems with Real-Time Scan and Batch Scan (실시간스캔과 배치스캔을 갖춘 안티바이러스시스템의 운영 분석)

  • Yang, Won Seok;Kim, Tae-Sung
    • The Journal of Korean Institute of Communications and Information Sciences
    • /
    • v.38B no.11
    • /
    • pp.861-869
    • /
    • 2013
  • We consider an information system where viruses arrive according to a Poisson process with rate ${\lambda}$. The information system has two types of anti-virus operation policies including 'real-time scan' and 'batch scan.' In the real-time scan policy, a virus is assumed to be scanned immediately after its arrival. Consequently, the real-time scan policy assumes infinite number of anti-viruses. We assume that the time for scanning and curing a virus follows a general distribution. In the batch scan policy, a system manager operates an anti-virus every deterministic time interval and scan and cure all the viruses remaining in the system simultaneously. In this paper we suggest a probability model for the operation of anti-virus software. We derive a condition under which the operating policy is achieved. Some numerical examples with various cost structure are given to illustrate the results.

WAP-EPO 유전자 도입 형질전환돼지의 계대번식시 유전자 전이효율에 관한 연구

  • 이연근;박진기;민관식;성환후;임기순;양병철;김광식;김진회;장원경
    • Proceedings of the KSAR Conference
    • /
    • 2001.03a
    • /
    • pp.14-14
    • /
    • 2001
  • 본 연구는 생명공학 관련 기술개발에 의하여 신소재 물질을 생산하고 사람에게 안전하고 생리활성이 높은 고가의 의료용 단백질 생산기술을 체계화하며 형질전환 가축을 이용한 유용물질 생산에 따른 산업화와 부가가치의 극대화에 그 목적이 있다. 유즙으로 사람의 빈혈치료제인 EPO(Erythropoietin)를 분비할 수 있는 형질전환돼지를 생산하기 위하여 WAP(Whey Acidic Protein) Promoter(2.6kb) 하류에 사람의 조혈촉진유전자(EPO: 2.6kb)를 연결시켜 미세주입용 재조합 벡터(WAP-EPO : 약 7.8kb)를 구축하였다. 구축된 재조합 벡터를 1세포기 수정란에 약 2ng/ul 농도로 미세주입한 다음 외과적 방법으로 이식하였다. 이식 후 분만 모돈으로부터 생산된 자돈의 꼬리조직을 이용 게놈DNA를 추출하고 PCR 검정을 한 결과, 유즙으로 사람의 빈혈치료제를 생산할 수 있는 유전자가 도입된 형질전환돼지 $\boxDr$새롬이$\boxUl$ (♂)를 확인하였다. 또한 이렇게 꼬리조직으로부터 확인된 새롬이의 혈액과 정액을 채취, 게놈 DNA를 추출하여 외래 유전자 삽입여부를 PCR 방법으로 검정한 결과 꼬리조직과 마찬가지로 혈액 및 정액에서도 외래유전자가 삽입되었음을 확인할 수 있었다. 이렇게 생산된 형질전환돼지 $\boxDr$새롬이$\boxUl$를 이용 계대번식을 통한 F$_1$ 산자의 생산과 유전자 전이율을 확인하기 위하여 $\boxDr$새롬이$\boxUl$정액을 이용한 인공수정을 실시하였다. 인공수정은 1999년 7월 1일부터 2000년 9월 8일 까지 총 78두의 모돈을 이용하였으며, 그 중 21두의 모돈이 분만하여 인공수정에 의한 분만율은 26.92%로 나타났다.(Table Omitted) Table 1에서와 같이 새롬이 정액을 이용한 인공수정에 의해 형질전환된 F$_1$ 자돈의 형질전환율은 17.98%로 나타났으며, 32두의 형질전환자돈 중 8두(암:4두, 수:4두)는 분만과 동시에 폐사하였거나 사육중 폐사하여 현재 24두(암:12두, 수:12두)가 생존하여 F$_1$ 간 교배계획에 의해 사육되고 있다. 이 중 암컷 4두는 현재 F$_2$ 자돈 생산과 함께 유즙내로 사람 빈혈치료제의 분비 유무를 검정중에 있으며, FISH 법에 의한 외래 유전자 삽입 검정을 확인 중에 있다.

  • PDF

Anatomy, Biomechanics and Physical Examination of Foot and Ankle (족부 및 족관절의 해부학, 생역학 및 신체 검사)

  • Hur, Chang-Yong;Kim, Hak Jun
    • The Journal of Korean Orthopaedic Ultrasound Society
    • /
    • v.3 no.1
    • /
    • pp.32-37
    • /
    • 2010
  • Ultrasonographic diagnosis and treatment in Orthopaedic fields had been widely used. Sonographic diagnosis and treatment of foot and ankle is convenient because of anatomical characteristics. The knowledge of the anatomy and biomechanics in foot and ankle area can help to diagnose and treat the disease around foot and ankle. 28 bone and many tendons, ligaments and muscles are consist of ankle and foot joint and the coordinative relation among these structures can allow the dual function, weight bearing and locomotion of ankle and foot during gait cycle. Foot and ankle have small room for many structures, so systemically physical examination is essential for diagnosis. Accurate understanding of foot and ankle anatomy and biomechanics could be helpful to using ultrasonograph.

  • PDF

The Effect of Reminiscence Therapy on Communication Ability of Elderly Patient With Alzheimer's Dementia (회상하기 프로그램이 알츠하이머 노인의 의사소통 능력에 미치는 영향)

  • Kim, Soo-Jung;Chang, Hyun-Jin
    • Therapeutic Science for Rehabilitation
    • /
    • v.9 no.4
    • /
    • pp.21-31
    • /
    • 2020
  • Objective : Reminiscence program is a method to restore psychological stability for the elderly having dementia, and at the same time it makes the aged with dementia express themselves correctly by helping them to recollect their past life memories. The purpose of this study was to investigate the effects on communication ability in applying the reminiscence program to elderly patients with Alzheimer's dementia. Methods : The subject were 4 patients whose Alzheimer's dementia of moderate. This experiment was designed with pre-stage, treatment-stage, post-stage. The reminiscence therapy was compose of reminiscence activities of their live; in their childhood, adolescence, adulthood, and senescence. The therapy was delivered 30 times for 15 weeks. Results : The result of the study were as follows. First, after reminiscence therapy, recognition ability was improved. Second, after reminiscence therapy, emotional side was improved. Third, after reminiscence therapy, communication ability was improved. Conclusion : In this study, the reminiscence therapy had a positive effect on the improvement of communication skills among the elderly with Alzheimer's dementia. Based on the reminiscence therapy, it is thought to be very helpful in improving the communication ability of the elderly with dementia in the future.

A Study on the Development of a Program to support VFSS by using Deeplearning (딥러닝을 활용한 VFSS를 도와주는 프로그램 개발 연구)

  • Choi, Dong-gyu;Jang, Jong-Wook
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
    • /
    • 2018.10a
    • /
    • pp.58-61
    • /
    • 2018
  • In Korea, current medical technology is the highest level in the world. As a result, many doctors have specialized knowledge of various disorders or diseases, and are proceeding in a better way. With such high medical technology, it is possible to increase the probability of success of surgery to provide high reliability to patients. Rehabilitation is also a form of medical treatment that reduces the side effects that occur after surgery that is done for quick cure. However, the situation in this section is slightly different. There are moves to develop rehabilitation devices and operations, but most of them are now dependent on foreign technology. Rehabilitation therapy, which we commonly know, is dominated by behavior. However, it is also a kind of rehabilitation to find out how much the patient's symptoms are improved or recovered. In this paper, we have studied the development of a program by using the Deeplearning method in order to detect the problem of the food swallowing operation by the severity.

  • PDF

Research of 6MeV electron dose distribution (Electron therapy에서의 dose distribution에 관한 연구)

  • Je Jae Yong;Park Chul Woo;Jin Sung Jin;Park Eun Tae
    • 대한방사선치료학회:학술대회논문집
    • /
    • 2005.06a
    • /
    • pp.27-32
    • /
    • 2005
  • Electron is used for the treatment of skin cancer, breast cancer, and head and neck cancer in clinic. Our study is performed to check the isodose distribut ion in source surface distance(SSD) and source bolus distance(SBD) setup, nipple influence to isodose distribution of electron, junctional area isodose variation of photon and electron field. Dosimetry is carried out with phantom, acryl, and film as the same condition of treatment setup. $8\%$ of isodose difference is noted with the surface distance(SSD) and source bolus distance(SBD) setup. To reduce the influence of nipple. corresponding volume of bolus should be removed. And bolus covering all the electron field reduced hot and cold spot of junctional area of photon.

  • PDF

A Case of Pulmonary Paragonimiasis with Chronic Abdominal Pain and Erythematous Rash in a 6-year-old Girl (만성 복통과 발진을 주소로 내원한 6세 여아에서 진단된 폐흡충증 1예)

  • Kim, Ju Young;Park, Min Kyu;Lee, Yong Ju;Huh, Sun;Cho, Ky Young
    • Pediatric Infection and Vaccine
    • /
    • v.25 no.1
    • /
    • pp.54-59
    • /
    • 2018
  • Pleural paragonimiasis is uncommon in the pediatric population and therefore can be challenging to diagnose. This is a case of a 6-year-old girl with pleural effusion who had been having intermittent persistent epigastric pain and erythematous rash on the face, hands, and arms for 6 months. Exudative pleural effusion with prominent eosinophils and serum eosinophilia were observed. As patient showed high immunoglobulin M (IgM) titers against Mycoplasma pneumoniae, she was treated with antibiotics; however, the pleural effusion did not improve during hospitalization. Despite showing negative stool ova and cyst results, patient's serum and pleural effusion were positive for Paragonimus westermani-specific IgGs on enzyme-linked immunosorbent assay. Respiratory symptoms, pleural effusion, and skin symptoms improved after praziquantel treatment.