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고 선량율 근접 및 온열치료 병용 삽입관의 제작과 특성

  • 추성실;김성규
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2003.09a
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    • pp.52-52
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    • 2003
  • 악성종양을 치료하는 방법중 방사선과 온열요법은 가장 강력한 치료방법으로 연구되어왔으며 이를 병용함으로 서 상승효과를 얻을 수 있다. 인체조직에 41$^{\circ}C$ 이상의 열을 가하면 세포질의 단백질변성으로 세포에 손상을 주어 세포가 사멸하게 되며 세포의 생존율은 가열시간 즉 열량에 따라 지수적으로 감소한다. 온열은 세포주기중 방사선 저항성이 매우 큰 DNA 합성시기와 산도가 높을 때 감수성이 매우 크기 때문에 방사선과 병용요법은 상호 상승효과를 가져온다. 이와 같이 온열을 이용한 악성종양의 치료가능성은 생물학적 기초연구와 임상시험에서 경이적인 효과를 얻을 수 있었으나 아직 까지 가열방법과 온도분포측정이 큰 과제로 남아있으며 주위건강조직의 가열을 피하면서 인체 깊은 곳에 존재하는 종양에만 집중 가열하는 방법인 삽입형 온열치료방법에 대한 연구가 집중되었다. 한편 방사선 치료방법은 주위 건강조직의 피폭을 최소로 줄이고 종양에만 집중 조사가 요구되며 자궁암, 유방암, 뇌암등 부피가 작고 집중적 치료를 요하는 종양은 방사성동위원소를 이용한 근접 삽입치료 (Brachyradiotherapy)가 큰 효과를 나타내고 있다 방사선과 온열의 병행 치료를 위하여 방사선 삽입 치료에 사용한 선원 삽입관을 그대로 두고 삽입관 속에 방사성 동위원소 대신 온열 전극을 넣어 열을 가하는 방사선 온열 병용치료방법을 고안하였으며 방사선과 온열병용에 사용할 최적 삽입관의 제작과 이에 따른 온도분포의 측정과 최적삽입방법을 결정하였다. 방사선 삽입치료용 폴리에찌렌 삽입관의 외부에 금박을 입혀 라디오파 첨극을 삽입할 때 서로 연결되도록 고안 제작함으로서 방사선 삽입치료와 자입식 온열치료를 동시에 만족하게 수행할 수 있는 병용삽입관 (Flexible thermoradiotherapy probes)을 제작하였다. 전도율이 큰 금박부위가 직접 조직에 접촉됨으로 라디오파의 전달이 용이하며 금박의 길이를 2 cm 에서 5 cm 로 구분제작 함으로서 종양의 크기와 모양에 따라 선택할 수 있도록 하였다. 라디오파를 이용한 온열분포의 측정은 인체조직과 전기적 특성이 비슷한 물질인 한천 팬텀 제작하여 사용하였으며 온도분포 측정은 열전대와 서머그람으로 시행하였다. 생체조직 내에서의 온도분포와 온열효과를 관찰하기 위하여 직접 개의 뇌를 이용하여 시행하였으며 4 개의 전극을 이용하여 43$^{\circ}C$로 50분간 가열하고 일주일후 개를 회생시켜 개 뇌에 대한 조직학적 검사를 시행하였다. 한편 팬텀 표면에서 중앙부로 안테나 길이가 2 cm 인 4 개의 전극을 1 cm 간격으로 정사각형이 되도록 삽입하여 가열하였을 때 90% 등온곡선이 반경 1.25의 원형으로 균일하게 분포되었고 종단면상 삽입관의 길이에 따라 균일한 온도분포가 이루어졌다. 전극을 2 cm 간격으로 삽일 하였을 때 90% 등온곡선이 1.75 반경으로 거의 4 각형의 균일한 분포를 얻었으나 전극의 간격이 증가하면 전도율이 떨어져서 전극 중심부에 불균일한 온도분포를 형성하였다. 동물실험에서 정상 개의 뇌 실질에 자입하여 직접 정방형의 중심을 43$^{\circ}C$로 유지하며 50분간 온열 요법을 시행한 후 관찰한 조직병리학적 소견은 liquefactive necrosis, pyknosis of neuronal element 및 polymorphonuclear leukocytes들의 회백질에서 급성기에 관찰되었고 liquefactive necrosis 주위에 lipid-laden macrophage들이 관찰됨이 공통적인 특정이었으며 후기변화로 괴사조직 주위로 신경교세포의 증식이 관찰되었다.

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In Vivo Dosimetry with MOSFET Detector during Radiotherapy (방사선 치료 중 MOSFET 검출기를 이용한 체표면 선량측정법)

  • Kim Won-Taek;Ki Yong-Gan;Kwon Soo-Il;Lim Sang-Wook;Huh Hyun-Do;Lee Suk;Kwon Byung-Hyun;Kim Dong-Won;Cho Sam-Ju
    • Progress in Medical Physics
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    • v.17 no.1
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    • pp.17-23
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    • 2006
  • In Vivo dosimetry is a method to evaluate the radiotherapy; it is used to find the dosimetric and mechanical errors of radiotherapy unit. In this study, on-line In Vivo dosimetry was enabled by measuring the skin dose with MOSFET detectors attached to patient's skin during treatment. MOSFET dosimeters were found to be reproducible and independent on beam directions. MOSFET detectors were positioned on patient's skin underneath of the dose build-up material which was used to minimize dosimetric error. Delivered dose calculated by the plan verification function embedded in the radiotherapy treatment planning system (RTPs), was compared with measured data point by point. The dependency of MOSFET detector used in this study for energy and dose rate agrees with the specification provided by manufacturer within 2% error. Comparing the measured and the calculated point doses of each patient, discrepancy was within 5%. It was enabled to verify the IMRT by using MOSFET detector. However, skin dosimetry using conventional ion chamber and diode detector is limited to the simple radiotherapy.

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The Taoist Ideology of Psychoanalytic Psychology and the Future Development Trend of Art Therapy (정신분석 심리학의 도교사상과 예술치료의 미래 발전 트렌드)

  • Li Huisshu
    • The Journal of the Convergence on Culture Technology
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    • v.9 no.2
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    • pp.437-444
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    • 2023
  • With the development of modern society, society provides people with a quick and convenient life, but it also causes anxiety, depression, other psychological and mental illnesses, so art can also be used as a way and path to treating psychological disorders. Art therapy is a creative method of delivery used in therapy, resulting from the fusion of art and psychotherapy. Art is a service and public art activity, mainly aimed at solving human psychological problems, providing nonverbal expression and communication opportunities, and treating psychological and psychological entanglement by improving emotion, stability, and indirectly inappropriate behavior through multi-disciplinary convergence. Art therapy, as an independent discipline, began in Europe in the 3rd and 40th centuries and was mainly influenced by two psychologists, Sigmund Freud and Carl (Gustav Jung). We Starting with the theoretical foundation of psychoanalysis, this paper explores the effectiveness of modern people's psychotherapy, analyzes the similarities between the two ideas, explores the application of art therapy and the development of science and technology, and provides the public with various ways of art therapy and the validity of science and technology.

Clinical results of arthroscopic meniscal repair according to joint stability (반월상 연골의 관절경적 봉합시 관절안정성에 따른 결과)

  • Kyung Hee-Soo;Ihn Joo-Chul;Baek Seung-Hoon
    • Journal of the Korean Arthroscopy Society
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    • v.6 no.1
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    • pp.37-42
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    • 2002
  • Purpose : The purpose of this study was to evaluate the results of arthroscopic meniscal repair according to joint stability. Materials and Methods : Twenty cases were reviewed, which had underwent arthroscopic meniscal repair. The mean age was 32.3 years old. The mean follow-up period was 59.7 months. Menisci that had underwent complete repair of associated ligament injuries (8cases, Sa) and menisci that had no associated ligament injury (9 cases, Sb) were classified as stable group (S), and the others (3 cases) as unstable group (U). Also stable group was divided into acute and chronic group. The result was evaluated with Lysholm score and IKDC method. The statistical analysis was done using Wilcoxon rank sum test and Fisher's exact test (p<0.05). Results : Group Sa had $87.5\%$ satisfactory and Lysholm score was 90.9. Group U had $66.7\%$ satisfactory, and Lysholm score was 77.7. Group Sb had $89.9\%$, satisfactory and Lysholm store was 91.4. In acute group $91.7\%$ was satisfactory, Lysholm score 92.5, in chronic group $80\%$ was satisfactory, Lysholm score 88.6. Conclusion : Joint stability was important factor for the outcome of meniscal repairs. So, it is desirable to repair meniscus injury early and the repair of associated ligament injuries should be performed together.

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Endoscopic Submucosal Dissection for Simultaneous Presence of GIST and Submucosal Tumor Type MALT-Lymphoma on the Stomach ? (동시에 발견된 위장관 간질 종양과 점막하 종양 형태의 MALT 림프종의 내시경 치료)

  • In Kyung Yoo;Hoon Jai Chun;Yoon Tae Jeen;Bora Keum;Eun Sun Kim;Hyuk Soon Choi;Seung Joo Nam
    • Journal of Digestive Cancer Research
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    • v.2 no.1
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    • pp.24-27
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    • 2014
  • A 42-year-old female was referred to our department after find out submucosal tumor type lesion on cardia at local clinics. She experienced no specific symptom. On gastroscopy, two distinct neoplasms were detected. One of which was located in the cardia anterior wall of the stomach with the size of 2.0×1.1 cm, and the other one was localized in the cardia posterior wall of the stomach and its size was 1.5×1.2 cm. We performed endoscopic submucosal dissection. Pathological evaluation revealed the diagnosis of gastrointestinal stromal tumor (GIST) at the cardia anterior wall and malignant lymphoma from the mass localized cardia posterior wall of the stomach. We would like to report these rare synchronous tumors which were successfully treated by endoscopic resection in the same patient

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Study of Validity and Reliability of the Korean Translation Version of the Sensory Processing and Self-Regulation Checklist (SPSRC) (한글판 감각처리 및 자기조절 체크리스트(SPSRC)의 타당도와 신뢰도 연구)

  • Kim, Ye-Eun;Lee, Hye-Rim;Lee, Sun-Min
    • The Journal of Korean Academy of Sensory Integration
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    • v.21 no.3
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    • pp.27-38
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    • 2023
  • Objective : This study aims to verify the validity and reliability of the Korean version of the Sensory Processing and Self-Regulation Checklist (SPSRC) for children with and without autism spectrum disorder. Methods : The Pearson product-moment correlation coefficient was calculated using Short Sensory Profile (SSP) to verify concurrent validity. Construct validity was verified by comparing the sensory processing ability and self-regulation ability of the two groups. Cronbach's α was calculated in the case of internal consistency for reliability verification, and the test-retest reliability was verified through the Pearson correlation coefficient. Results : Based on the verification of the concurrent validity, the Korean version of SPSRC and SSP showed a statistically significant correlation (p < 0.01). The construct validity was found to have a statistically significant difference between the two groups in the area and sub-items of the Korean version of SPSRC (p < 0.001). For the internal consistency, Cronbach's α ranged from 0.700 to 0.975. The test-retest reliability showed that the correlation coefficient ranged from 0.937 to 0.997. Conclusion : The Korean version of SPSRC was confirmed to be an evaluation tool with high validity and reliability. It is expected to be used as an evaluation tool for planning treatment goals in clinical trials and as a meaningful basis for future research.

Studies on Ringworm in Military Horses 1. Clinical Observations and Therapeutic Experiments (군마(軍馬)에 발생(發生)한 윤선(輪癬)에 관한 연구(硏究) I. 임상증례보고(臨床症例報告) 및 치료시험(治療試驗) 성적(成績))

  • Kim, Man Young;Kang, Yung Bai
    • Korean Journal of Veterinary Research
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    • v.13 no.2
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    • pp.165-170
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    • 1973
  • 1972년 여름, 사관생도(士官生徒) 승마교육용(乘馬敎育用)으로 육군사관학교(陸軍士官學校) 군마대(軍馬隊)에서 사육(飼育)하고 있는 승마용(乘馬用) 마필(馬匹)(오스트레일리아 및 일본산(日本産))과, 군용마(軍用馬)로서의 개발시험(改發試驗)에 공시중(供試中)인 제주도산(濟州道産) 재내마필(在來馬匹)에 발생(發生)한 14예(例)의 피부사상균성(皮膚絲狀菌性) 윤선(輪癬)을 대상(對象)으로 그 치료시험(治療試驗)을 실시(實施)하였던 바, 다음과 같은 결론(結論)을 얻었다. 임상증례(臨床症例) 관찰(觀察) (1) 초기증상(初期症狀) 발현(發現)은 군마고유번호(軍馬固有番號) 15번(番), 마명(馬名) 거상(巨象)(원명(原名) Shane)의 이마 및 이근부(耳根部) 견부(肩部)에 직경(直徑) 3cm 정도(程度)의 원형(圓型) 병소(病巢)가 나타났으며, 곧 이어 다른 마필(病巢)에 산발적(散發的)으로 발생(發生)했다. 발생률(發生率)은 31.8%(군마(軍馬) 44%, 조랑말 15.8%)로서 지난해 군부대(軍部隊) 목장(牧場)에서 집단발생(集團發生)했던 Bovine Ringworm의 발생률(發生率)(56.4%)보다 낮았다. (2) 증상(症狀)은 원형발진(圓型發疹) 및 양감(痒感), 가피형성(痂皮形成), 피모탈낙(皮毛脫落), 농포형성(膿疱形成) 및 신모발생등(新毛發生等)의 순(順)으로 진행(進行)했으며 환축(患畜)과 접촉(接觸)하는 사람에게도 감염(感染)하는 인축공통전염병(人畜共通傳染病)의 일종(一種)이었다. (3) 품종(品種) 및 성별(性別), 연령에 따른 유의성(有意性)은 인정(認定)할 수 없었다. 치료시험(治療試驗) 결과(結果) (1) 본병(本病)은 Ichthammol이나 Undecylenic Acid 처리(處理)에 있어서 치료효과(治療效果)를 나타냈다. (2) 상기(上記)한 항사상균제 처리(處理)와 동시(同時)에 Hydrccortisone의 보조요법(補助療法)을 실시(實施)하였을때, 약효(藥效)가 빨리 나타나고 치료기일(治療期日)도 단축(短縮)되었다. (3) 본증(本症)은 조기(早期)에 발견(發見) 치료(治療)해야하며 일반적(一般的)으로 완치(完治)하는데 장기간(長期間)을 요(要)하였다.

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A case report on acquired torticollis (후천성(後天性) 사경증(斜頸症) 환자(患者) 치험(治驗) 1례(例))

  • Won, Ho-Young;Lee, Dong-Won;Choi, Eun-Jung;Kim, Kyong-Soo;Kim, Eun-Jung
    • Journal of Oriental Neuropsychiatry
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    • v.14 no.1
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    • pp.141-147
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    • 2003
  • Objectives : The symptom of torticollis caused by abnormal contraction in cervical muscles, is easily found among those who get much stress physically and mentally in modern society. Due to this disease, the patients suffer not only from psychologic distress for appearance but also from functional disorder. Therefore, this case is to look for the effective treatment and understandings on the spasmodic torticollis. Methods : Herb medicine is used Guibi-tang(歸脾湯), Heosu-san(回首散), Hyangso-san(香蘇散) and Samul-tang(四物湯). Manipulation therapy is used stretching and meassage technique on cervical muscles. Self exercise of cervical and lumbosacral muscles, physical therapy with ultra sound carried out. Result and Conclusion : Acquired spasmodic torticollis effectively is treated with herb medicine, manipulation, exercise and physical therapy.

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조신(調神)을 통한 질병(疾病) 치료(治療) 연구(硏究) (I) -관어이조신치료질병적연구(關於以調神治療疾病的硏究)(I)-

  • Jeong, Ho-Jin;Baek, Yu-Sang;Jeong, Chang-Hyeon
    • Journal of Korean Medical classics
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    • v.18 no.4 s.31
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    • pp.27-43
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    • 2005
  • 통과대(通過對)${\ulcorner}$내경(內經)${\lrcorner}$ 중출현적조신적개념급용조신치병적방법적연구(中出現的調神的槪念及用調神治病的方法的硏究), 득출여하결론(得出如下結論): 조신이양생지의(調神以養生之意), 용우지금(用于至今). ${\ulcorner}$내경(內經)${\lrcorner}$중신지의(中神之意), 우기표현위여우주자연지신(尤其表現爲與宇宙自然之神)[천신(天神)]상응적인체지신(相應的人體之神)[인신(人神)]상(上), 즉천인상응적사상교위돌출(卽天人相應的思想較爲突出) 형신상호관계상(形神相互關係上), 재유지형신합일적사상적동시(在維持形神合一的思想的同時), 비기양형경가중시어조신(比起養形更加重視於調神). 재양생방면(在養生方面), 조신의조시간급공간(調神依照時間及空間), 분위사시조신화오장신조신(分爲四時調神和五臟神調神). ${\ulcorner}$소문(素問).사기조신대론(四氣調神大論)${\lrcorner}$적요지시이사시출현적자연계적변화규율(的要旨是以四時出現的自然界的變化規律), 응대청정적우주정신래수련신심(應對淸靜的宇宙精神來修練身心). ‘이념요법(移念療法)’시통과개변재인체오장내정기적운행위치(是通過改變在人體五臟內精氣的運行位置), 진행치료적방법(進行治療的方法). 기내용개괄료기타각종정신요법(其內容槪括了其他各種精神療法). 대지언고론요법적한의학해석(對至言高論療法的韓醫學解釋), 불시이이유오행혹음양이론작위의거(不是以已有五行或陰陽理論作爲依據), 이시가종사상의학중조도. 기원인시사상의학적출발점(其原因是四象醫學的出發點), 불시이단순적육체무병작위기목적(不是以單純的肉體無病作爲其目的). 저일점(這一點), 종명확지표현재수세보원적성명사단론중(從明確地表現在壽世保元的性命四端論中). 대생리병리독특적유심론관(對生理病理獨特的唯心論觀), 시이제마선생탁월관점(是李濟馬先生卓越觀点). 한방음악치료초월료이행동주의심리학위중심(韓方音樂治療超越了以行動主義心理學爲中心), 발전기래적기유적음악요법적국한성(發展起來的旣有的音樂療法的局限性), 약여약물(若與藥物), 침구치료병용(鍼灸治療倂用), 불근가이치료신경정신질환(不僅可以治療神經精神疾患), 환가이치료기타각종신체질환(還可以治療其他各種身體疾患). 기공시이응신(氣功是以凝神), 의수(意守), 의념등표현(意念等表現), 작위기주요조신방법적일종수신법(作爲其主要調神方法的一種修身法).

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A New Bot Disinfection Method Based on DNS Sinkhole (DNS 싱크홀에 기반한 새로운 악성봇 치료 기법)

  • Kim, Young-Baek;Youm, Heung-Youl
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.18 no.6A
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    • pp.107-114
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    • 2008
  • The Bot is a kind of worm/virus that can be used to launch the distributed denial-of-service(DDoS) attacks or send massive amount of spam e-mails, etc. A lot of organizations make an effort to counter the Botnet's attacks. In Korea, we use DNS sinkhole system to protect from the Botnet's attack, while in Japan "so called" CCC(Cyber Clean Center) has been developed to protect from the Botnet's attacks. But in case of DNS sinkhole system, there is a problem since it cannot cure the Bot infected PCs themselves and in case of CCC there is a problem since only 30% of users with the Botnet-infected PCs can cooperate to cure themself. In this paper we propose a new method that prevent the Botnet's attacks and cure the Bot-infected PCs at the same time.