• Journal of Chest Surgery
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• v.39 no.7 s.264
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• pp.544-548
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• 2006

Background: The purpose of this study is to evaluate the validity of a combined high saphenous vein division and sclerotherapy without sacrificing saphenous vein for varicose vein. Material and Method: Between August 2004 and October 2005, 70 limbs in 50 patients were treated by a combined high saphenous vein division and sclero-therapy. The operative indication is valvular incompetence of femoral-saphenous or popliteal-saphenous junction. Patients received local anesthesia and were treated by a combined high saphenous vein division, ligation of incompetent perforating vein and $1{\sim}3%$ sclerosant. Patients received 1 day hospitalization and applied in com-pression stocking for 6 weeks. Patients followed after 1 week, 1 and 3 months. Result: Mean age of patients was $50{\pm}11$. The female was more common. 8 patients was no symptom, another 42 patients complained of pain, heaviness and fatigue of limbs. The symptoms of varicose vein disappeared 1 month after the procedure in all symptomatic patients. 8 patients needed a adjuvant sclerotherapy for residual varicose vein on 1 week after the procedure. There were only minor complications such as hematoma (1), wound infection (1), thrombophlebitis (20), skin blister (10), hyper-pigmentation (1), and skin ulcer (1). Conclusion: We concluded that a combined high saphenous vein division and sclerotherapy without sacrificing saphenous vein for varicose vein is simple, less invasive, economical, and effective treatment for primary varicose vein, and it has a special advantage that saphenous vein can be used as a bypass conduit later. The method was selective in old aged patients.

• The Journal of the Convergence on Culture Technology
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• v.1 no.2
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• pp.85-89
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• 2015

It has been reported that cerebral disease is the most leading to death as a single disease even though next to cancer in the most important cause of death in the country. Even if patients maintain a life without death, it will have to suffer from side effects such as hemiplegia and language disorders. In this paper, the symptoms and treatment of cerebral infarction cases are described through the medical dramas (The Third Hospital, The Brain) and movie (Amur). Even if there is the same stroke each drama or movie, depending on the previous history or current physical condition of the patient knew which treatment the law is different.

• Journal of Food Hygiene and Safety
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• v.9 no.3
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• pp.169-174
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• 1994

This stydy was performed to investigate the inhibitory effect of bovine milk on the atherosclerotic rats. Eighty male rats of 5-weeks of age were divided into 4 groups, control, active treatment control fed the atherogenic feed, and skim milk and whole milk groups fed powdered skim or whole milk mixed with the atherogenic feed and observed for 13 weeks. Growth, clinical and pathological changes of the rats were examined. Rats of the 4 groups did not show significant difference of feed intake and weight gain. The level of serum cholesterol, high density lipoprotein cholesterol (HDL-cholesterol) fraction, and inorganics between skim milk and whole milk groups were not significantly different though significant difference was shown between active treatment control and milk groups. Milder calcification and nearosis in aorta, heart and kidney and fat degeneration in liver were seen in the milk groups than were in active treatment control. Marked difference, however, was not found between the skim milk and whole milk groups. Both powdered skim and whole milks could have a helpful effect of vitamin D2-and -cholesterol-induced atherosclerosis in rats.

• Journal of Pharmacopuncture
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• v.11 no.3
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• pp.55-66
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• 2008

Objective&Methods: The purpose of this study is to observe the effects of HK-1000 Herbal-acupuncture solution at GB34(Yangleungchean) on hyperlipidemia and arteriosclerosis in rats. The author performed several experimental items to analyze the levels of various components and enzymes in serum, urine and liver, as well as the histological change of liver and aorta. Results: 1. HK-1000 herbal-acupuncture infusion increased the cell viability rate, DPPH radical scavenging activity and HMG-CoA reductase inhibition rate in rat liver cells. 2. The levels of total cholesterol, free cholesterol, LDL-cholesterol, phospholipid in serum and AI(atherogenic index) were decreased, and the ratio of HDL to TCL(HDL/TCL) and the level of TG in serum were increased as compared with those of the control group. 3. In the HK-1000 group, serum AST and ALT were significantly lower than those of the HG group and saline group. 4. Hepatic GSH and catalase activities were significantly increased as compared with those of the saline group. Conclusions: From the above results, it is suggested that HK-1000 herbal-acupuncture at GB34 has a therapeutic effect on hyperlipidemia and arteriosclerosis.

• Journal of Periodontal and Implant Science
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• v.33 no.2
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• pp.179-191
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• 2003

Since periodontal infections are suggested as risk factors for the development of cardiovascular diseases, the present study was performed to evaluate the T cell immune responses specific to Pophylomonas gingivalis(P. gingivalis) heat shock protein(hsp) 60 and T-cell and B-cell epitope specificities for P. gingivalis hsp60 in atherosclerosis. Anti-P, gingivalis IgG antibody titers were elevated in all patients. We could establish P. gingivalis hsp-specific T cell lines from the atheroma lesions, a mixture of $CD4^+$ and $CD8^+$ cells producing the cytokines characteristic of both Th1 and Th2 subsets. of 108 overlapping synthetic peptides spanning whole P. gingivalis hsp60 molecule, ten peptides with common epitopes specificities for both T-cell and B-cell were identified. it was concluded that P. gingivalis hsp60 might K involved in the immunoregulatory process of atherosclerotic diseases with epitope specificities.

• Journal of Periodontal and Implant Science
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• v.35 no.1
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• pp.1-8
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• 2005

Bacterial heat shock protein has been one of the components that are responsible to induce autoimmune disease mechanisms in the pathogenesis of atherosclerosis due to high level of homology in sequence with human counterpart. This mechanism may explain how bacterial infectious disease, such as periodontal disease, might contribute to the acceleration of the disease process of atherosclerosis. Porphyromonas gingivalis which is a major periodontal pathogenic bacterial species, has been implicated as one of the pathogenic bacteria playing the role in this context. The present study has been performed to evaluate the anti-atherosclerotic effect of adoptive transfer of Porphyromonas gingivalis heat shock protein epitope-specific T cell lines into severe combined immunodeficiency (SCID) mice. Peptide no. 15 with amino acid sequence VKEVASKTND-specific T cell line was selected for the transfer. When experimental atherosclerosis was induced in SCID mice adoptively transferred either by the T cell lines (experimental group) or by non-specific mouse T cells (control group), there was no significant difference in the severity and extent of the atherosclerosis induced by hypercholesterol diet.

• Culinary science and hospitality research
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• v.5 no.2
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• pp.59-89
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• 1999

본 연구는 기존의 삼계탕재료에 해동피와 갈근의 축출액을 넣어서 조리를 하여 특성변화와 기호도를 검토하고자 4주령(28일)의 부로일러 종 50수 각 처리구당 해동닭 15수, 삼계탕 15수, 일반닭 15수씩 총 3개 처리구에 배치하여 상품개발을 위한 실험결과를 요약하면 다음과 같다. 영양분석에서 단백질은 해동닭이 작게는 10.07%~11.08%까지 높게 분석되었고 지방은 해동닭이 삼계탕보다는 0.04% 더 많으며 일반닭보다는 4.65%나 작았다. 특히 적육(Red-meat)에서는 다른 흰살(White-meat) 고기의 닭고기에서는 우리인체에 중요한 작용을 하는 생체의 성장기능, 번식기능과 치료효과의 동맥경화증, 혈전억제 효과가 있다고 하는 불포화지방산(Omega-polyunsaturated fatty acide, 3, 6)( $\omega$-3, 6)을 함유하고 있어 지속적인 식도락가의 사랑을 받을 것으로 예측된다. 회분함량도 상대적으로 많으며 수분도 조리의 특성상 증발하지 못한 관계로 그대로 있어 수분과 조리로 인하여 손실되는 영양상태를 그대로 유지할 수가 있었다. 관능테스트에서는 <그림2-1, 2, 3>과 <표 2-10>에서 분석결과를 보듯이 제일 중요한 점은 고객의 기호도라 볼 수 있겠다. 시각적인 면만 약간 개선된다면 정말로 말할 수 없을 정도로 흡족한 상품이라 할 수 있겠다. 해동닭이 후각 90%, 맛 97%, 조직도 83%, 만족도 97%를 보면 그 누가 훌륭한 상품이라고 하지 않겠는가 하는 아쉬움을 가지며 시각적인 면도 해동피, 갈근, 황기, 인삼, 밤, 마늘, 대추, 은행, 생강, 고추 등 고객의 관심도가 높은 의 한약재료가 들어가는 것을 안다면 그리 문제가 되지 않는다고 보며 단지 문제가 있다면 우리 국민 의식이 가공식품에 대한 인식전환과 시기적인 환경, 국민소득 12,000불대의 시대에 맞는 상품이기를 바란다.

• Journal of the Korean Society of Food Science and Nutrition
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• v.23 no.1
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• pp.170-179
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• 1994

Atherosclerosis, a multifactorial disease, is closely related to lipid nutrition , Data from well known epidemiological studies including Seven Country , Framinghsam Study and several intervention trials have confirmed that serum cholesterol is the major risk factor and elevation of LDL-cholesterol level is most undesriable. On the basis of results concurring in that dietary saturated fat and cholesterol increase serum cholesterol while polyunsaturated fat decrease it, changes in serum choesterol level have been predicted by regression equations developed by Keys et al. and other investigators. Effects of individual fatty acids on the level of serum cholesterol have been further differentiated by chain length, cis-trans isomers and n-6 vs n-3 polyunsaturated fatty acids. Among them the effect of n-3 fatty acids has been well recogniaed as antiplatelet activity, thus reducing the incidence of atherosclerosis. Role of vitamin E in prevention of atherosclerosis has been evovled from works showing that LDL oxdiation stimulates formation of ateroma and also from epidemiologic studies. Dietary recommendations at present are : (ⅰ) 30 and 10 cal % as upper limit of total and saturated fat intakes, respectively (ⅱ) no more than 300 mg cholesterol/day, (ⅲ) 1-2 g of n-3 fatty acid/day and (ⅳ) some increase RDA of vitamin E which is 8-10 TE.

• Journal of Korean Medicine Rehabilitation
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• v.21 no.4
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• pp.269-279
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• 2011

Objectives: The purpose of this study was to investigate the clinical application of blood-letting therapy and oriental medicine with arteriosclerosis obliterans. Methods: The patient in this case had been already treated by anticoagulation, percutaneous transluminal angioplasty and thrombolysis. But these methods didn't work on patient and condition had gone bad. Finally the patient's left limb was about to be amputated. Patient did not wall to cut off her lower limb, so she visited us to find a way for treating and preserving her lower limb. A drastic treatment was necessary in this situation. We treated the patient with Korean traditional treatment. Specially excessive blood-letting therapy and oriental medicine helped the patient to decrease the pain, numbness and frigidity. Results: After treatment the chief complaint and accompanying symptoms were subsided and improved. And personal and social performance scale was increased. Conclusions: According to this study, Korean traditional treatment such as blood-letting therapy, and oriental medication is effective for the cure of arteriosclerosis obliterans. During this period, foot necrosis was delayed and amputation is not needed any more.

• Journal of the Korean Society of Food Science and Nutrition
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• v.23 no.2
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• pp.192-197
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• 1994

Effect of pine pollen and defatted pine pollen on lipid accumulation and metabolism in serum and liver were investigated with rats fed high fat-supplemented diets for 6 weeks. Concentrations of total lipid and total cholesterol in serum significantly decreased in the experimental groups (treated with pine pollen and defatted pine pollen) compared with the control group. Concentration of triglyceride in serum was remarkably lower than that of control group. This was similar to that of normal group. Concentration of glucose in serum was significantly lower in the experimental group. It was observed from photographs of hepatic tissue in rats that pine pollen inhibits the lipid accumulation induced by high fat diets.