• KIPS Transactions on Computer and Communication Systems
• /
• v.12 no.2
• /
• pp.77-84
• /
• 2023

Dengue virus transmission is a viral infection disease between humans and Aedes mosquitoes. Dengue is ubiquitous throughout the tropics and subtropical zones, where 1/3 of the global population live. The weather in Korea is also changing to subtropical weather, resulting in increased vulnerable Korean population to dengue virus transmission. It is important to control and prevent the dengue risk with track-recording & monitoring system. It is also required to have the control system to treat and monitor dengue patients with various cases such as regions, ages, genders according to the track-record of the disease. In this paper, we developed a Dengue Control & Prevention System, which can monitor and control dengue outbreaks in real-time with in-vitro diagnostic devices. Dengue Control & Prevention System is composed of in-vitro diagnostic device, which is a fluorescent immunoassay, and real-time monitoring system. In the future, we expect that our Dengue Control & Prevention System can be upgraded to have various disease information from Korea Disease Control and Prevention Agency for government policies and diseases control in Korea.

• Iberoamérica
• /
• v.21 no.2
• /
• pp.1-23
• /
• 2019

This study analyzes how the health program is implemented by political and economic factors in the case of Minga Ambiental program in Paraguay. In the field of critical medical anthropology, the practice of health care programs explains that socio-cultural and political and economic factors can be the main variables besides the primary purpose of preventing and eradicating the disease. In the same vein, this study also analyzed how community-based health programs operate by various external factors. As a result, the Minga Ambiental program is a health program called Dengue Fever, which has been tended to be sustained and expanded by various actors, including politicians and corporations in countries and communities, despite concerns about effectiveness. In this case, this study found that health programs can be operated by political and economic relations different from their original purpose, and are intertwined in various social contexts by various actors in constructing health programs.

• 건강소식
• /
• v.11 no.12 s.109
• /
• pp.40-41
• /
• 1987

• Pediatric Infection and Vaccine
• /
• v.20 no.2
• /
• pp.98-104
• /
• 2013

Dengue fever is an important health problem for international travelers to all endemic areas. The steadily increasing numbers of tourists visiting endemic areas raise the risk of exposure, and imported dengue cases are increasingly observed in nonendemic area. Dengue has a wide spectrum of clinical presentations, often with unpredictable clinical evolution and outcome. While most patients recover following a self-limiting, non-severe clinical course, a small proportion progress to severe disease such as dengue hemorrhagic fever or dengue shock syndrome. Therefore, it is important to suspect dengue fever in every febrile patient returning from the tropics. Whenever it is suspected, a quick diagnosis and adequate managements are essential to avoid complications. We report two cases of imported dengue fever in Korean children presenting with fever, headache, nausea, and rash.

• The Journal of the Korea Contents Association
• /
• v.19 no.2
• /
• pp.259-268
• /
• 2019

Dengue virus is a typical mosquito-borne virus, and the half of the world's population is exposed to infection. Dengue virus causes relatively mild symptoms such as dengue fever. However, when not treated properly, it is known to cause severe symptoms such as dengue hemorrhagic fever and dengue shock syndrome with a mortality rate of over 20%. Development of dengue virus detection technology is very important because it is reported that early diagnosis of dengue fever can lower the mortality rate to less than 1%. In this study, patent search related to dengue virus detection technology was conducted in Korea, USA, Europe, Japan, and China. The quantitative analysis of 69 validated patents from the searched patents was conducted by country, year, and patent holder. In addition, in-depth analysis was carried out by classifying into three categories: molecular diagnostics, immuno-diagnostics, and cell culture-based diagnostics from all validated patents. From these results, we analyzed the patent trend related to dengue virus detection and dengue fever diagnosis technology and discussed the features and limitations of molecular diagnostics and immuno-diagnostics at present level. Furthermore, we discussed the direction of technology development and future prospects to overcome limitations.

• Proceedings of the Korea Information Processing Society Conference
• /
• 2020.11a
• /
• pp.1031-1033
• /
• 2020

최근 지구온난화에 따른 기온 및 강수량 증가 등으로 인해 모기 개체 수가 증가함에 따라 말라리아, 일본뇌염, 뎅기열 등 모기를 통해 전파되는 질병에 감염병의 위험률도 높아지고 있어 머신러닝기반 기후 데이터를 활용하여 모기 개체 수를 예측할 수 있는 모델을 제안하였다.

• Pediatric Infection and Vaccine
• /
• v.27 no.2
• /
• pp.140-146
• /
• 2020

Dengue fever (DF) is endemic throughout tropical and subtropical regions; however, it is not endemic in Korea. Imported infectious diseases should be suspected when encountering returned travelers with non-specific symptoms such as fever, rash, and headache. Persistent vomiting, abdominal pain, hemorrhagic tendency, hepatic enzyme abnormalities, and proteinuria are risk factors for the development of severe DF in a patient with DF. Severe hyperglycemia is also known to be related to poor prognosis in acute illness, and with certain underlying diseases that present with hyperglycemia, such as diabetes, it is related to the progression of severe DF. We report a DF case with severe hyperglycemia in an adolescent returning from India. Pediatric DF cases reported in Korea were also reviewed.

• Proceedings of the Korea Contents Association Conference
• /
• 2015.05a
• /
• pp.225-226
• /
• 2015

뎅기 바이러스는 전 세계적으로 빠르게 확산되고 있는 모기 매개 바이러스이다. 현재까지 4가지의 혈청형이 알려져 있는 뎅기 바이러스는 뎅기열, 뎅기 출혈열과 뎅기 쇼크증후군 등을 유발한다. 현재 뎅기 바이러스가 전 세계적으로 확산되고 있음에도 불구하고 확실한 치료제나 백신이 없기 때문에 초기 진단이 매우 중요하다. 아열대기후로 진입하는 우리나라에서도 흰줄숲모기가 자주 발견되기 때문에 이 질병으로부터 결코 자유롭지가 않다. 바이러스 감염을 진단하기 위한 진단키트를 개발하기 위해서는 타깃 유전자 부위 선정이 매우 중요하기 때문에 본 연구에서는 먼저 생명정보학을 기반으로 뎅기 바이러스만을 특이적으로 검출할 수 있는 항월결정부위를 예측하고 진단키트에 적용하고자 하였다. 4가지 유형의 뎅기 바이러스 유전자들을 찾고, ProtScale Tool 프로그램으로 친수성(hydrophilicity), 접근성(acc -essibility), 유연성(flexibility), 회전(${\beta}-turns$) 등의 특성을 분석하여 항원결정부위를 선정하였다. 이 항원결정부위를 이용하여 단일클론항체를 제작하였으며 향후 진단키트로의 적용 가능성을 확인하였다.

• KOREAN POULTRY JOURNAL
• /
• v.36 no.7 s.417
• /
• pp.96-101
• /
• 2004

사람들이 모기를 싫어하는 이유는 많다. 모기는 사람과 가축에 각종 병원체를 옮기며, 또한 많은 스트레스를 주고, 이로 인한 정신적인 피해가 크기 때문이다. 가축에서는 가축이 수면을 제대로 취하지 못하게 하고, 질병을 일으켜서 경제적인 피해를 입히기도 한다. 모기로 인해 육계는 성장이 늦어지고, 산란계에서는 산란율이 떨어진다. 사람이 모기에 물리게 되면 간지럽고, 빨갛게 붓는 피부 알러지가 생기고, 잠잘 때 윙윙 소리를 내어 수면을 방해한다는 점, 그로 인한 불쾌감, 정신적 스트레스 등의 피해를 입는다. 그러나 무엇보다도 모기가 주는 가장 큰 피해는 각종 질병을 옮기고 다닌다는 것이다. 모기로 인해 옮겨지는 병으로는 뇌염(encephalitis), 마랄리아(malaria), 상피병(filaria), 황열병(yellow fever), 뎅기열(dengue fever) 등을 들 수 있다. 그 중에서도 국내에서 발병하는 병은 일본뇌염(Japanese encephalitis), 말라리아, 상피병 등이 알려져 있다. 가축에서 오는 모기 매개 질병은 소의 아까바네병, 유행열, 이바라기병 및 츄잔병, 아이노바이러스 감염증 등이 있고, 돼지에서는 사람에게 뇌염을 일으킬 수 있는 돼지일본뇌염이 있고 닭에서는 닭류코사이토준병이 있다.

• The Korean Journal of Mycology
• /
• v.43 no.2
• /
• pp.77-87
• /
• 2015

Insects are commonly infected by fungal diseases and are mostly susceptible to them. Increasing levels of insecticide resistance has recently become an issue for control programs; thus, research has focused on mosquito control using entomopathogenic fungi, including fungal pathogens such as Beauveria bassiana, Metarhizium anisopliae, and Lagenidium giganteum. Review discusses entomopathogenic fungi related to control programs for mosquito transmitted vector-borne diseases such as dengue, filariasis, malaria, and yellow fever, and how to use entomopathogenic fungi for mosquito control.