• Title/Summary/Keyword: 대사 경로

Search Result 501, Processing Time 0.029 seconds

여름철의 모돈의 사양관리

  • Jang, Won-Gyeong
    • The Korea Swine Journal
    • /
    • v.10 no.6 s.106
    • /
    • pp.57-61
    • /
    • 1988
  • 여름철 모돈의 사육환경은 고온과 과습에 주의하고 사료 섭취와 단백질 이용 효율 및 대사효율이 저하하기 때문에 지방을 사료에 첨가해야 한다. 특히 하절기에는 번식을 피하는 것이 좋으며, 일년중 번식계절을 세우는 것이 생산효율을 증대시킨다.

  • PDF

Research trends, applications, and domestic research promotion stratigies of metabolomics (대사체학의 연구 동향, 응용 및 국내 연구 활성화 방안)

  • Kim, So-Hyun;Yang, Seung-Ok;Kim, Kyoung-Heon;Kim, Young-Suk;Liu, Kwang-Hyeon;Yoon, Young-Ran;Lee, Dong-Ho;Lee, Choong-Hwan;Hwang, Geum-Sook;Chung, Myeon-Woo;Choi, Ki-Hwan;Choi, Hyung-Kyoon
    • KSBB Journal
    • /
    • v.24 no.2
    • /
    • pp.113-121
    • /
    • 2009
  • As one of the new areas of 'omics' technology, there is increasing interest in metabolomics, which involves the analysis of low-molecular-weight compounds in cells, tissues, and biofluids, and considers interactions within various organisms and reactions of external chemicals with those organisms. However, metabolomics research is still at a fundamental stage in Korea. Therefore, the purpose of this study was to establish a strategic long-term plan to revitalize the national metabolomics approach and obtain the elementary data necessary to determine a policy for effectively supporting metabolomics research. These investigations clarified the state of metabolomics study both in Korea and internationally, from which we attempted to find the potentiality and fields where a metabolomics approach would be applicable, such as in medical science. We also discuss strategies for developing metabolomics research. This study revealed that promoting metabolomics in Korea requires cooperation with metabolomics researchers, acquisition of advanced technology, capital investment in metabolomics approach, establishment of metabolome database, and education of metabolome analysis experts. This would reduce the gap between the national and international levels of metabolomics research, with the resulting developments in metabolomics having the potential to greatly contribute to promoting biotechnology in Korea.

Menthol biosynthesis pathway in Mentha piperita suspension cells (박하(Mentha piperita) 세포 현탁배양에서 멘톨생합성 경로)

  • Park, Si-Hyung;Chae, Young-Am;Lee, Hyong-Joo;Kim, Soo-Un
    • Applied Biological Chemistry
    • /
    • v.36 no.5
    • /
    • pp.358-363
    • /
    • 1993
  • The metabolic capability of the cultured cells of peppermint was tested with whole intact cells by feeding appropriate exogenous substrates to the suspension cultures. Conversion of (-)-limonene into any other monoterpenes was not observed with the suspension cultures. (+)-Pulegone was converted into (+)-isomenthone and (-)-menthone, and (-)-menthone into (-)-menthol. The experiments confirmed that the suspension retained most of the menthol biosynthesis pathway in the cell except for a few loci. (-)-Isopiperitenone was transformed into (+)-pulegone, piperitenone, (-)-7-hydroxyisopiperitenone and two unidentified products.

  • PDF

Enzymatic and Genetic Aspects of Glyoxalase I in Microorganisms (미생물에 있어서 글리옥살라아제 I의 효소학적, 유전학적 고찰)

  • 이해익
    • Microbiology and Biotechnology Letters
    • /
    • v.18 no.1
    • /
    • pp.103-108
    • /
    • 1990
  • The enzymatic studies on the methylglyoxal metabolism in yeast and bacterial cells indicated that organisms are equipped with the common and manifold systems for the detoxification of methylglyoxal. Among these systems, the glyoxalase I is the most important route for methylglyoxal detoxification. The molecular structure of glyoxalase I is apparently distinct from the enzyme sources, and zinc ion is an essential cofactor in enzyme activity. The gene for Pseudomonas putida glyoxalase I functioned as a scavenger of methylglyoxal and regulated the cell size of the bacterium. Comparison of the nucleotide sequence of the P. putida glyoxalase I gene with the N-terminal amino acid sequence of the purified enzyme revealed that the N-terminal methionine residue was removed after translation. Possible physiological role of glyoxalase I was also discussed.

  • PDF