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Development of a Core management Algorithm for Optimal Design of AMBIDEXTER Transient Cores (AMBIDEXTER 천이노심 설계최적화를 위한 노심관리 알고리즘 개발)

  • Yu, Geuk-Jong;Sin, Dong-Hun;So, Sun-Gyu;Lee, Yeong-Jun;Kim, Jin-Seong;O, Se-Gi
    • Proceedings of the Korean Nuclear Society Conference
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    • 2004.10a
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    • pp.99-100
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    • 2004
  • AMBIDEXTER-NEC의 천이노심은 $^{Nat}Th$$^{Nat}U$의 주입만으로 전 출력의 Break-even 노심에 도달하기위한 중간 단계이다. 선행연구에서 수행한 전 출력노심인 평형노심의 핵종수밀도에 도달하기 위해서 평형노심에서의 기저물질, 잠재핵분열성물질, 핵분열물질의 수밀도를 각 SEU-기반, Pu-기반, ADS-기반에서 그대로 유지하여 초기노심을 구성하였다. 또 각 시나리오에 대해 최대첨두출력과 원자로의 안전성을 고려해 Excess Reactivity를 5mk 내에서 초기노심을 결정하였다. 각 노심은 주 핵분열성물질 $^{235}U$, $^{239}Pu$$^{233}U$의 핵반응단면적 특성에 따라 평균 전환율이 각각 0.95, 0.83 및 1 .21 로서 핵연료물질의 적절한 선택만으로도 전환로, 연소로 및 증식로로 설계할 수 있음을 보여준다. 이러한 $Th/^{233}U$, U/Pu 핵연료주기를 사용하는 AMBIDEXTER-NEC 용융염핵연료 원자로의 초기노심에서 시작한 천이노심은 평형노심에장전할 충분한 $^{233}U$ 양을 확보해야 하므로 천이노심의 목표는 평형노심 $^{233}U$의 요구량에 최소한의 기간에 가장 적은 외부주입을 통해 도달하는 것이다. 천이노심에서 임계가 유지되는 AMBIDEXTER-NEC 원자로시스템의 3군 핵종변환 코드인 HELIOS-SQUID-AMBIBURN 체제를 개발하였고 그림 1.에 나타내었다. 이 알고리즘은 각 초기노심 중원소의 미시단면적, 중원소를 제외한 원소들의 거시단면적, 임계도를 만족하는 중성자속 및 외부주입율을 계산하여 SQUID 및 AMBIBURN 입력자료를 제공한다. 또한 일정시간 중원소의 핵종농도, 외부주입율과 중성자속이 일정하다는 가정 하 에 반복수행 하고 SEU-기반과 Pu-기반의 경우에는 각각 핵변환을 거쳐 재순환되는 $^{233}U$$^{239}Pu$의 양을 바로 주입하는 최대재순환 경우와 평형노심 요구 장전량에 이를 때까지 시설 내 저장하는 최소재순환 경우로 상황을 모사하였다. 그림 2 는 각 시나리오별 초기노심에서부터 200FPD까지 단위 용융염 체적당 $^{233}U$의 수밀도 시간변화를 나타낸 것이다. 그림을 보면 50일 이후부터는 수밀도의 변화가 일정한 기울기를 보이고 있고 재처리공정에서 $^{233}Pa$를 분리하는 최소재순환의 경우에는 최대재순환보다 2-3%정도에 지나지않아 그림에서 나타내지않았다. SEU-기반 및 Pu-기반에서 $^{233}U$의 증가율이 각각 2.54E+13, 2.81E+13 #/cc/d 로 Pu 기반이 조금 더 큰 증가율을 나타내고 있지만 평형노심 농도 1.04E+20 #/cc/d 에 도달하기 위해서는 두 경우 모두 매우 긴 시간이 걸릴 것을 예상할 수 있다. 요컨대 250MWth AMBIDEXTER-NEC가 평형노심을 이루기 위해 필요로 하는 $^{233}U$을 생산하는데 제안한 SEU-기반, Pu-기반 시나리오는 천이노심주기기간이 전형적인 원자로 수명 3-40년 보다 매우 큰 것으로 나타났다. 따라서 장전될 $^{233}U$의 확보를 위한 최적옵션은 초기노심부터 ADS와 같은 외부생산시설로부터 전량을 공급 받아 운전하는 것이라 판단된다.

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Recent Advances in Cancer Diagnosis: On an Overview of Diagnostic Cytopathologic Modalities and Ancillary Techniques (세포병리학적 기초에 의한 암진단의 발전: 진단방법과 보조기법)

  • Kim, Ki-Tai;Ham, Eui-Keun
    • The Korean Journal of Cytopathology
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    • v.7 no.1
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    • pp.1-11
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    • 1996
  • From the concepts of cellular pathology and of exfoliative cytology, as elucidated by Virchow and Papanicolaou respectively in the late 19th and early 20th century, have evolved the primary methods for the diagnosis of cancer today. From Papanicolaou's concept of exfoliative cytology developed fine needle aspiration biopsy in the early 1960's, this has become a major diagnostic procedure and has contributed to a significant reduction in open biopsies and, therefore, to medical cost-effectiveness immunobiochemical techniques provided us with a supplement to cancer diagnosis in the 1980's. The immunoperoxidase method, using monoclonal antibodies, is applied primarily as an ancillary measure to elucidate the nature of cancers The availability of specific monoclonal antibodies has greatly facilitated the identification of cell products or surface markers. For example, antibodies directed against intermediate filaments have proved to be of value in determining the histogenesis oi poorly differentiated neoplasms. Tumor markers may serve as biochemical indicators of the presence of a neoplasm. They can be detected In plasma and other body fluids. Their concentration can be applied as a diagnostic test, for monitoring the clinical course of known cancer, and as a screening measure to detect certain cancers in a population at risk. Flow cytometry is a useful tool for distinguishing several cell characteristics, such as the immunophenotype of leukemia-lymphoma cells, the DNA content of neoplastic cells, and cell proliferation rate. Molecular biologic techniques provided a giant step for the management of cancer patients encompassing diagnosis, prognostic evaluation, and therapy. Nucleic acid hybridization techniques are utilized as Southern, Northern, and dot blots and in situ hybridization. Molecular biology and its techniques may bring a blight new horizon for understanding cancer biology and in designing therapy on the basis of gene manipulation.

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Research on Immune Enhancing Effect and Safety of Wasong (Orostachys japonicus) Extract: Study Protocol for a Single Center, Randomized, Double-blind, Placebo-controlled, Clinical Trial (와송 추출물의 면역기능 개선 효과 및 안전성 연구: 단일기관, 무작위배정, 이중눈가림, 위약대조 비교, 임상연구 프로토콜)

  • Choi, Jin Yong;Choi, Jun Yong;Lim, Hyun Woo;Kim, Jeong;Kim, So Yeon;Han, Chang Woo
    • Herbal Formula Science
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    • v.25 no.2
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    • pp.135-143
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    • 2017
  • Objectives : This trial aimed to determine if Wasong (Orostachys japonicus) extract can enhance immune system and is safe enough to be approved as a health functional food. Methods : Total 62 people, aged 45 and older, will be recruited to participate in a randomized, double-blind, placebo-controlled clinical trial. This study will compare Wasong extract and placebo. Wasong group will take 1g of Wasong extract, once a day, for 8 weeks. Placebo group will take 1g of crystalline cellulose as placebo, once a day, for 8 weeks. Outcomes will be measured at the baseline, the end of 4th week, and 8th week. Primary outcomes are the ratio of NK cells/total lymphocytes and the ratio of T-helper cells/T-suppressor cells. Secondary outcomes are total white blood cell count, the ratio of neutrophils, lymphocytes, and monocytes in total leukocytes, the ratio of total T cells, T-helper cells, T-suppressor cells, and B cells to lymphocytes, the amount of blood IgM, IgG, IgA, and cytomegalovirus (CMV) IgG, and blood metabolite target &global analysis. Results : This trial was approved by institutional review board of Pusan National University Korean Medicine Hospital (registry number: 2016006), and registered in Clinical Research information Service, one of WHO International Clinical Trials Registry Platform (registry number: PRE20161006-002). Recruitment opened in February 2017 and is supposed to be completed by August 2017. The result is expected to be published by June 2018. Conclusion : This trial will provide clinical information to determine the efficacy and safety of Wasong in enhancing immune system of middle-aged and older people.

Relationship among User's Security Need Sufficiency, Customer Satisfaction and Life Satisfaction in Electronic Security System (기계경비시스템 이용자의 안전욕구충족과 이용만족 및 생활만족의 관계)

  • Kim, Chan-Sun
    • The Journal of the Korea Contents Association
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    • v.9 no.7
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    • pp.257-267
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    • 2009
  • This study aims at diagnosing the relationship among user's security need Sufficiency, customer satisfaction and life satisfaction in electronic security system. For the achievement of this study selected electronic security system users in Seoul as a population for about 25 days from June 20$^{th}$, 2008 to July 15$^{th}$, 2008, segmented. This study selected 378 peoples by distributing 400 unities in total for each 80 peoples throughout purposive sampling method. The final 302 samples were used in statistics. Collected data was analyzed based on the aim of this study using SPSSWIN 16.0, and factor analysis, reliability analysis, stepwise multiple regression analysis and path analysis were used as statistic techniques to analyze. The conclusions are the followings; First, The higher bodily, environmental, mental, informational, and physical security need the more body and property protection satisfaction and facility customer satisfaction. The higher bodily, environmental, and mental security need the more employee service satisfaction. Second, The higher bodily, environmental, informational, and physical security need are perceived, the more influence is marked with life satisfaction and security life satisfaction. Third, The higher personal and property protection, facility, and employee service satisfaction the more security life satisfaction. Also, the higher customer service and personal and property protection satisfaction are perceived, the more influence is marked with life satisfaction. Fourth, Security need sufficiency has little influence on life satisfaction directly, but it has high influences on life satisfaction through customer satisfaction of electronic security system.

Growth Variation among the Different Populations of Sea Urchin, Pseudocentrotus depressus (분흥성게의 지역별 개체군 성장에 관한 연구)

  • CHUNG Sang-Chul;NATSUKARI Yutaka
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.28 no.4
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    • pp.421-427
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    • 1995
  • To know the variation in the growth of the sea urchin, Pseudocentrotus depressus according to their localities, three different populations including the culture populations, the released populations, and the wild populations were investigated using the cluster analysis. For this purpose, pigment banding pattern on the genital plate was used as an age character. The population composed of the same year class was born between September 25th and October 5th every year. The population of 9 to 10 months old had no $r_1,\;whereas\;r_1$, was observed in the population of either 1 year and 10 or 11 months old, and both $r_1,\;and\;r_2$ in the population of either 2 year and 9 or 10 months old. Therefore, $r_1,\;and\;r_2$ radius were regarded as an annual ring. Growth in the culture populations was much better than that In either the released or the wild populations. However, when the cultured populations composed of 8 to 12 mm in test diameter was released to the shove near a culture farm, its growth appeared to be similar to that of the wild Populations. The wide distribution patterns of test diameter measured from the same year class of both the cultured and the wild populations were probably due to either long spawning period or growth differences between individuals. Except Yamaguchi and Cheju populations, the move closely located populations showed the more similar growth pattern. However, the growth of Cheju population appeared to be similar to that of Aba, Mogi, Toishi rather than Kasiwazima although Cheju Island was more closely located with Kasiwazima than other localities. In addition, the population of Yamaguchi, located at the highest latitute, revealed the similar growth pattern to that of Nomozaki, located at the lowest latitute.

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Relationship among User's Security Need Sufficiency, Customer Satisfaction and Life Satisfaction in Electronic Security System (기계경비시스템 이용자의 안전욕구충족과 이용만족 및 생활만족의 관계)

  • Kim, Chan-Sun
    • Proceedings of the Korea Contents Association Conference
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    • 2009.05a
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    • pp.614-619
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    • 2009
  • This study aims at diagnosing the relationship among user's security need Sufficiency, customer satisfaction and life satisfaction in electronic security system. For the achievement of this study selected electronic security system users in Seoul as a population for about 25 days from June 20th, 2008 to July 15th, 2008, segmented Han river based in 5 areas and extracted 1 dong per each area. This study selected 378 peoples by distributing 400 unities in total for each 80 peoples throughout purposive sampling method. The final 302 samples were used in statistics. Collected data was analyzed based on the aim of this study using SPSSWIN 16.0, and factor analysis, reliability analysis, stepwise multiple regression analysis and path analysis were used as statistic techniques to analyze. The conclusions are the followings; First, The higher bodily, environmental, mental, informational, and physical security need the more body and property protection satisfaction and facility customer satisfaction. The higher bodily, environmental, and mental security need the more employee service satisfaction. Second, The higher bodily, environmental, informational, and physical security need are perceived, the more influence is marked with life satisfaction and security life satisfaction. Third, The higher personal and property protection, facility, and employee service satisfaction the more security life satisfaction. Also, the higher customer service and personal and property protection satisfaction are perceived, the more influence is marked with life satisfaction. Fourth, Security need sufficiency has little influence on life satisfaction directly, but it has high influences on life satisfaction through customer satisfaction of electronic security system.

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High Conversion Gain Millimeter-wave Monolithic Subharmonic Mixer With Cascode Harmonic Generator (Cascode형 하모닉 발생기를 이용한 고변환이득 특성의 밀리미터파 단일칩 Subharmonic 믹서)

  • An, Dan;Kim, Sung-Chan;Sul, Woo-Suk;Han, Hyo-Jong;Lee, Han-Shin;Uhm, Won-Young;Park, Hyung-Moo;Kim, Sam-Dong;Rhee, Jin-Koo
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.40 no.5
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    • pp.197-203
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    • 2003
  • In this paper, we have presented millimeter-wave high conversion gain quadruple subharmonic mixers adopting the cascode harmonic generator The subharmonic mixers were successfully integrated by using 0.1 ${\mu}{\textrm}{m}$ GaAs pseudomorphic HEMTs(PHEMTs) and coplanar waveguide(CPW) structures. Measured output of 1st, 2nd and 4th harmonics of the fabricated cascode 4th harmonic generator are -21.42 dBm, -32.65 dBm and -13.45 dBm, respectively, for an input power of 10 dBm at 14.5 GHz. We showed that the highest conversion gain of 3.4 dB has obtained thus far at a LO power of 13 dBm from the fabricated subharmonic mixers. The millimeter-wave subharmonic mixer also ensure a high degree of isolation showing -53.6 dB in the LO-to-IF and -46.2 dB in the LO-to-RF, respectively, at a frequency of 14.5 GHz. The high conversion gain achieved in this work is the first report among the millimeter-wave subharmonic mixers.

A Study on Clutter Rejection using PCA and Stochastic features of Edge Image (주성분 분석법 및 외곽선 영상의 통계적 특성을 이용한 클러터 제거기법 연구)

  • Kang, Suk-Jong;Kim, Do-Jong;Bae, Hyeon-Deok
    • Journal of the Institute of Electronics Engineers of Korea SC
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    • v.47 no.6
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    • pp.12-18
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    • 2010
  • Automatic Target Detection (ATD) systems that use forward-looking infrared (FLIR) consists of three stages. preprocessing, detection, and clutter rejection. All potential targets are extracted in preprocessing and detection stages. But, this results in a high false alarm rates. To reduce false alarm rates of ATD system, true targets are extracted in the clutter rejection stage. This paper focuses on clutter rejection stage. This paper presents a new clutter rejection technique using PCA features and stochastic features of clutters and targets. PCA features are obtained from Euclidian distances using which potential targets are projected to reduced eigenspace selected from target eigenvectors. CV is used for calculating stochastic features of edges in targets and clutters images. To distinguish between target and clutter, LDA (Linear Discriminant Analysis) is applied. The experimental results show that the proposed algorithm accurately classify clutters with a low false rate compared to PCA method or CV method

An Analysis on the Repeated Error Patterns in Division of Fraction by Elementary Students (초등학생들이 분수의 나눗셈에서 보이는 반복적 오류 분석)

  • Kim, Kyung-Mi;Kang, Wan
    • Education of Primary School Mathematics
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    • v.11 no.1
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    • pp.1-19
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    • 2008
  • This study analyzed the repeated error patterns in division of fraction by elementary students through observation of their test papers. The questions for this study were following. First, what is the most changable thing among the repeated error patterns appeared in division of fraction by elementary students? Second, what is the most frequent error patterns in division of fraction by elementary students? First of all, the ratios of incorrect answers in division of fraction by general students were researched. This research was the only one time. The purpose was to know what kind of compositions in the problems were appeared more errors. Total 554 6th grade students(300 boys and 254 girls) from 6 elementary schools in Seoul are participated in this research. On the basis of this, the study for analysis began in earnest. 5 tests made progress for about 4 months. Total 181 6th grade students(92 boys and 89 girls) from S elementary school in Seoul were participated in this. After each test, to confirm the errors and to classify them were done. Then the repeated error patterns were arranged into 4 types: alpha, beta, gamma and delta type. Consequently, conclusions can be derived as follows. First, most students modify their errors as time goes by even though they make errors about already learned contents. Second, most students who appeared errors make them continually caused a reciprocal of natural number in the divisor when they calculate computations about '(fraction) $\div$ (natural number)'. Third, most students recognize that the divisor have to change the reciprocal when they calculate division of fraction through they modify their errors repeatedly.

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The Clinical study in 83 cases for colorectal cancer patients on the effects by Hangamdan(抗癌丹) (항암단(抗癌丹)을 투여(投與)한 대장암(大腸癌) 환자(患者) 83례(例)에 대한 임상보고(臨床報告))

  • Lee, Yong-Yeon;Seo, Sang-Hoon;Yoo, Hwa-Seung;Choi, Woo-Jin;Cho, Jung-Hyo;Lee, Yeon-Weol;Son, Chang-Kyu;Cho, Chong-Kwan
    • THE JOURNAL OF KOREAN ORIENTAL ONCOLOGY
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    • v.6 no.1
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    • pp.165-180
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    • 2000
  • Clinical studies were carried out 83 cases of patients with colorectal cancer treated by Hangamdan(抗癌丹) from January 1th 1998 to September 30th 2000. The results were summarized as follows; 1. Distribution of those attached by colorectal cancer, by sex, showed that Male is more then Female, by age, showed that the number of fifties is majority. 2. Distribution of diagnostic stage, in descending order; stage III(53%, top), stage IV(45.8%). 3. The effects of maintenance and improvement in the symptoms with traditional oriental therapy(83.3%) and combined treatment of western and oriental therapy(92.1%) were observed. The effects of the symptoms were as follows: diarrhea(37.3%), abdominal pain (25.3%), general body weakness(22.9%), nausea(20.5%) and etc. in orders. 4. Analysis of hematology attached by colorectal cancer, maintenance and increasing of WBC(89.9%), RBC(74.7%), Hgb(81.1%), Platelet(92.4%) were observed. After taken Hangamdan, the safety of the liver and kidney were as follows; maintenance and decreasing of AST(85.9%), ALT(94.8%), GTP(87.5%), Creatinine(90.9%) were observed. 5. of IL-12 and $IFN-\gammer$ attached by colorectal cancer, increasing of IL-12(53.3%), IFN-{\gammer}(80%)$) were observed. 6. Analysis of QOL attached by colorectal cancer, maintenance and improvement of combined treatment of western and oriental therapy(89.6%), traditional oriental therapy(83.3%) were observed. 7. Analysis of survival in patients with IV stage of colorectal cancer, above 7 months(18.4%), 12 months(65.8%). 8. Analysis of antitumor effects, maintenance of traditional oriental therapy(83.3%) and maintenance and improvement of combined treatment of western and oriental therapy(80.5%) were observed. Analysis of tumor marker attached by colorectal cancer, maintenance and decreasing of CEA(78.8%) were observed. 9. Analysis of curative valuation, maintenance and improvement of traditional oriental therapy(83.3%), combined treatment of western and oriental therapy(72.7%) were observed. From the above results, it is suggested that Hangamdan has significant effects of antitumor and immune activity, also could be usefully applied for colorectal cancer patients by combination with western therapy or alone.

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