• Journal of Korean Physical Therapy Science
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• v.27 no.3
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• pp.12-24
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• 2020

Purpose: This study was to investigate effects of aerobic exercise based korean traditional dance on vascular health, muscle strength and balance in the elderly with dementia. Design: Quasi-experiment design. Methods: Forty-two elderly participated in this study. All subjects were assigned experimental group (n=21), control group (n=21). Data were collected March to September 2019. Subjects in the experimental group performed aerobic exercise based korean traditional dance(three times a week, 30-50 minutes session, 24 sessions). Data were analyzed using descriptive statistics, Chi-square test, Fisher's exact test, independent t-test with the SPSS version 25.0 Results: The experimental group showed significantly increased vascular health (p<0.05), upper extremity strength (p=.022), dynamic balance (p=.026) compared to the control group. Conclusion: These results suggest that aerobic exercise based koran traditional dance is recommend a regular exercise program to enhance on vascular health, muscle strength and balance in the elderly with dementia.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.8
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• pp.449-455
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• 2018

This study was conducted to analyze the correlation between changes in white matter and homocysteine concentration through brain computed tomography of healthy 50-75 year old subjects without stroke or dementia history. We studied 722 out of 900 patients who underwent health screening at one hospital from 2016 to 2017. Based on the medical records, retrospective studies were conducted and analyzed using SPSS. A chi-square test, T-test and univariate logistic regression analysis were used for analysis. After the subjects were divided into the group with and without white matter changes, the population characteristics were analyzed. The mean age, homocysteine concentration and prevalence of hypertension and diabetes were higher and the duration of education was shorter in the group with white matter changes. In the group with white matter changes, the population increased as homocysteine concentration increased. When the odds ratio was compared based on the lowest group (Q1), age [p<0.001], hypertension [p<0.001] and hyperhomocysteinemia [p=0.021] were risk factors for white matter changes. We also identified modifiable risk factors such as hypertension and hyperhomocysteinemia to prevent complications of white matter changes. However, there has been no report of risk for the each causes of hyperhomocysteinemia and relationship between white matter changes and homocysteine concentration in Koreans. Therefore, large scale prospective studies are needed to better understand this topic.

• Journal of Life Science
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• v.13 no.5
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• pp.692-698
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• 2003

This study was designed to investigate the effects of ethyl acetate (EtOAc) fraction of pine (Pinus densiflora Sieb et Zucc) needle on membrane fluidity (MF), basal and induced oxygen radical (BOR and IOR), lipid peroxide (LPO) and oxidized protein (OP) as a oxidative stress, and lipofuscin (LF) in brain membranes of Sprague-Dawley (SD) rats. Male SD rats were fed basic diets (control) and experimental diets (EtOAc-25, EtOAc-50 and EtOAc-100) for 45 days. MF was significantly increased (about 10%) in mitochondria of EtOAc-100 group. BOR and IOR formations in mitochondria were significantly inhibited (about 9∼10% and 17∼24%, respectively) in EtOAc-50 and EtOAc-100 groups, while BOR and IOR formations in microsomes were significantly inhibited (about 12∼17% and 12∼16%, respectively) in EtOAc-50 and EtOAc-100 groups compared with control group. LPO levels in mitochondria and microsomes were significantly inhibited (about 9∼l2% and 12∼19%, respectively) in EtOAc-50 and EtOAc-100 groups, whereas significant difference between OP or LF levels and control group in these membranes could not be obtained. These results suggest that administrations of ethyl acetate fraction of pine needle may play an effective role in an attenuating an oxidative stress and in increasing membrane fluidity.