• Journal of the Korean Society of Radiology
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• v.1 no.1
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• pp.17-23
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• 2007

Background: Cerebrovascular diseases are known to show different patterns of incidence among regions and races. Therefore, it is very important to determine the incidence pattern of a specific area in order to diagnose, treat and prevent cerebrovascular diseases. The objective of the present study is to analyze quantitatively the incidence ratios of hemorrhagic and ischemic cerebrovascular diseases by season, by gender and by age. Methods: The subjects of this study were 1603 patients hospitalized for hemorrhagic or ischemic cerebrovascular diseases at the Department of Neurosurgery or the Department of Neurology of a University Hospital. Statistical analysis of data used Excel 2003 of Microsoft, and t-test was conducted using ORIGIN 6.0 of MICROCAL. Results: In the subjects, the incidence ratios of hemorrhagic and ischemic cerebrovascular diseases for four years, the period of this research, were 38.55% and 61.45%, respectively. The mean and standard deviation of age when hemorrhagic cerebrovascular diseases occurred were 58.20 and 12.60, respectively, and the percentages of subjects in their 40s, 50s, 60s and 70s were all around 20%. On the contrary, the mean and standard deviation of age when ischemic cerebrovascular diseases occurred were 65.01 and 13.59, respectively. The average age of patients with ischemic cerebrovascular diseases was older than that of patients with hemorrhagic brain diseases, and the percentages of those in their 60s, 70s and 80s were 15.53%, 37.06% and 27.72%, respectively. The season when hemorrhagic cerebrovascular diseases appeared most frequently was winter, which was followed by summer, spring and autumn. The season when hemorrhagic cerebrovascular diseases appeared most frequently was spring, which was followed by summer, winter and autumn. Conclusions: In this study, the incidence rates of hemorrhagic and ischemic cerebrovascular diseases were 38.55% and 61.45%, showing the rising percentage of ischemic cerebrovascular diseases. For making adequate prevention and disease control plans, it is considered necessary to make a long-term epidemiological investigation of cerebrovascular diseases.

• Journal of Chest Surgery
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• v.33 no.11
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• pp.869-875
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• 2000

배경: 뇌혈관계 합병증은 관상동백우회술 후 발생하는 사망률 중 10% 이상을 차지하는 치명적인 질환이다. 최근들어 고령 환자, 고혈압, 당뇨병 등이 병발하고 고 위험군에 대한 수술이 증가하면서 뇌혈관계 합병증은 오히려 증가하고 있다. 본 연구는 관상동맥우회술을 받은 환자의 의무기록을 조사하여 관상동맥우회술 후 발생되는 뇌혈관계 질환의 위험 인자를 밝히고자 한다. 대상 및 방법: 1991년 3월부터 1999년 7월 사이에 관상동맥우회술을 받은 185명을 조사하여, 뇌혈관계 합병증의 위험 인자들을 통계적으로 검증하였다. 결과: 뇌혈관계 합병증의 유병율은 7.57%(14명)였으며 이중 5예는 사망하였다. 동 기간 중 전체 사망은 11예이므로 사망자의 45.5%가 뇌혈관계 합병증으로 사망한 것이다. 통계적의의가 있는 뇌혈관계 합병증 위험 인자로는 수술 후 부정맥(p=0.0064), 기왕의 뇌혈관계 병력(p=0.0090), 체외순환시간(p=0.0181), 대동맥의 동맥경화(p=0.03575) 및 당뇨병(p=0.0452) 등이었다. 경동맥협착이 동반되어 경동맥 혈관내막 절제술(carotid endarterectomy)을 동시에 시술한 경우는 2예였으나, 뇌혈관계 합병증은 발생하지 않았다. 75세 이상의 고령환자는 3명이었으며 모두 뇌혈관계 합병증은 발생하지 않았다. 결론: 관상동맥우회술 후 발생하는 뇌혈관계 질환과 통계적으로 유의한 위험요인은 수술 후 부정맥, 뇌혈관이상의 기왕력, 체외순환시간, 대동맥궁의 동맥경화, 당뇨 등이었다.

• Proceeding of EDISON Challenge
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• 2017.03a
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• pp.631-634
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• 2017

뇌혈관은 평상시 뇌조직의 필요량보다 더 많은 혈류를 수송할 능력을 가지고 있는데 이를 뇌혈관 혈류예비력이라 한다. 뇌혈관이 특정한 요인에 의해 협착이 생기면 뇌관류압이 감소하는데 이를 보상하기 위해 뇌세동맥의 내경을 확장시켜 뇌혈류를 유지하도록 하는 것이다. 따라서 예비력이 낮은 사람일 경우 협착으로 인해 혈관 내경이 좁아져 있다면 운동이나 스트레스 상황에서 뇌졸증 내지 뇌허혈의 위험이 증가된다. 따라서 본 연구팀은 컴퓨터 시뮬레이션을 통해 뇌혈관 협착으로 인한 예비능 감소를 예측하였다. 이를 위해 환자의 MRA 영상 이미지를 영역화하여 3차원 격자를 생성하였으며 생성된 환자 맞춤 모델을 대상으로 전산유체해석을 진행하였다. 그리고 가상 협착을 모델에 적용하여 뇌혈관 협착률과 예비능의 관계를 분석했다.

• Journal of radiological science and technology
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• v.33 no.3
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• pp.223-230
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• 2010

The purpose of this study was to utilize Magnetic Resonance Imaging (MRI) and Magnetic Resonance Angiography (MRA) to analyze intracerebral regional distributions (hot spot) of ischemic cerebrovascular diseases which were characterized by stenosis and occlusion cerebral vasculature, except for cerebrovascular diseases induced by rupture of cerebral vasculature in terms of Korean people's cerebrovascular diseases, so that it could apply the findings of analysis to clinical practices. This study focused only on analyzing intracerebral regional distributions of ischemic cerebrovascular diseases that are characterized by stenosis and occlusion cerebral vasculature, because there are different etiologic mechanisms of ischemic cerebrovascular diseases like hemorrhagic cerebrovascular diseases (caused by rupture of cerebral vasculature) and cerebral infarction (induced by atheromatous arteriosclerosis). As a result, this study could come to the following findings of analysis: 1. According to sex ratio analysis, it was found that male group comprised larger portion of total 626 subjects in this study than female one (55.0% > 45.0%). 2. According to analysis on actual intracerebral regional distributions of ischemic cerebrovascular diseases, it was found that most subjects (37.5 %) were attacked by such diseases on the right side of cerebral vasculature, which was followed by left side of cerebral vasculature (35.1%) and bilateral cerebral vasculature (27.3%) respectively. 3. According to analysis on actual intracerebral regional distributions of ischemic cerebrovascular diseases, it was found that internal carotid artery (ICA) comprised the largest portion (38.9%) of those distributions, which was followed by middle cerebral artery (MCA, 35.7%), posterior cerebral artery (PCA, 13.4%), anterior cerebral artery (ACA, 6.0%) and vertebral artery (VA, 3.3%) respectively. 4. It was found that there was no subject attacked by any disease on A-com region, and there was only one male subject attacked by cerebrovascular diseases on P-com region. 5. It was found that female group was more susceptible to the attack of cerebrovascular diseases on MCA region than male one (54.6% > 42.2%), which means significant differences depending upon sex on statistical basis ($x^2$ = 9.64, p < .01). 6. It was found that male group was more susceptible to the attack of cerebrovascular diseases on ICA region (56.4% > 46.8%), which means significant differences depending upon sex on statistical basis ($x^2$ = 5.71, p < .05). 7. Moreover, it was also found that male group was more susceptible to the attack of cerebrovascular diseases on BA region (2.3% > 0.4%), which means significant differences depending upon sex on statistical basis ($x^2$ = 4.25, p < .05). 8. However, it was found that there was not any significant difference in intracerebral vasculature-specific distributions of cerebrovascular diseases depending on age of subjects, and stenosis comprised larger portion of cerebrovascular diseases than occlusion.

• 건강소식
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• v.9 no.12 s.85
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• pp.10-12
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• 1985

뇌혈관 장애로 인한 질환을 일컫는 총칭으로서 뇌혈관에 순환장애가 일어나 갑자기 의식장애와 함께 반신불수를 초래하는 급격한 뇌혈관병을 뇌졸중이라고 말하며, 구미에서는 ‘벼락같은 강타’를 받았다는 ‘Stroke나 Apoplexy'라하고 한국에서는 옛날부터 ’바람 맞았다‘는 뜻으로 중풍이라고도 말한다.

• The Monthly Diabetes
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• s.156
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• pp.24-27
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• 2002

모든 인체의 조직과 장기는 혈액순환을 통해 산소와 영양을 공급받고 노폐물을 배출하여 정상적인 기능과 활동을 유지하고 있다. 특히 뇌의 크기가 1300g 정도로서 무게로는 전체의 2$\%$정도밖에 안되지만 혈류의 20$\%$정도를 공급받을 만큼 매우 중요한 기관으로, 뇌는 뇌혈관을 통하여 지속적으로 산소와 영양을 공급받아야 정상적인 활동을 할 수 있다. 노인에서 증가하고 있는 고혈압, 당뇨병 등과 같은 만성질환은 여러 장기의 혈관에 동맥경화증을 유발하며, 특히 뇌혈관에 동맥경화증이 생기게 되면 혈관이 막혀 뇌혈류가 차단되어 뇌경색증이 발생하거나 뇌혈관이 터지게 되어 뇌출혈이 발생하게 된다. 이러한 뇌혈관의 급격한 변화로 뇌조직의 손상으로 인한 갑작스러운 신경마비 증상이 나타나게 되는데 이러한 증상을 통틀어 뇌졸중 또는 중풍이라고 한다.

• Journal of the Korean Society of Radiology
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• v.7 no.4
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• pp.293-299
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• 2013

The aim of this study is to investigate the correlation cerebrovascular disease factors in police officers, to provide basic data for a systematic and effective resource management of police officers in the future. This study was conducted on police officers who visited the national police hospital and who underwent MRI for the diagnosis of cerebrovascular diseases. In study result, the probability of cerebrovascular disease was 1.63 times higher in patients with a hypertension. And, the probability of cerebrovascular disease was 1.95 times higher in patients with a Cardiovascular disease. Beside, the probability of cerebrovascular disease was 0.54 times higher in patients with a drinking. And, the probability of cerebrovascular disease was 0.32 times higher in patients with a high homocysteine level.

• Journal of the Korean Society of Radiology
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• v.13 no.4
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• pp.495-502
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• 2019

A typical cerebrovascular disease among cerebrovascular diseases is vascular diseases such as cerebral infarction, cerebral hemorrhage, cerebral aneurysm, cerebrovascular stenosis. If the disease occurs and causes cerebral damage, it may be difficult to recover completely. So that, Must continue to perform health care through examination early. In particular, Because most cerebrovascular disease examining use radiation equipment and Thus this study was to find out how to select about the optimal examining method and X-ray dose decrease method among different examining method though comparison and analysis for the entrance surface dose (ESD) on cerebrovascular examining with Trance Femoral Cerebral angiography (TFCA) and Cerebral Computed Tomographic Angiography (CCTA). Also, want to find out how to select about the optimal examining method for worried patient that contrast medium side effect though measuring and evaluating for contrast usage. Data were collected from 70 patients (43 males and 27 females) who underwent CCTA at Yeosoo region hospital from June 2018 to December 2018 and 61 patients (34 males and 27 females) who underwent TFCA at Pyeongtaek region hospital from June 2018 to November 2018. ESD analysis method collected retrospective data though M-view and PACS PLUS program, Used contrast usage measuring method did reality measuring method. In the analysis using SPSS, the ESD of TFCA was $245.74{\pm}71.91$, which was $32.05{\pm}7.74$ lower than the dose of $277.79{\pm}79.65$ of CCTA ESD, and statistically significant at t = 3.249, p = 0.017 (p<0.05). As a result of the comparison of the total amount of contrast agent, the mean contrast agent used in TFCA was $55.05{\pm}17.68ml$, which was about 14.95 smaller than the amount of contrast agent used in CCTA, and statistically significant t = -4.548, p<0.001. In conclusion, the ESD of TFCA was statistically significantly lower than that of CCTA, and also the used contrast usage was significantly tiny than that of CCTA. Therefore, Select the method to increase the utilization of TFCA for cerebral disease examining, we can consider X-ray dose decrease method at the same time as to decrease side effect of contrast medium.

• Korean Journal of Veterinary Research
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• v.33 no.3
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• pp.443-454
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• 1993

Shiga-like toxin-II(SLT-II)-producing Escherichia coli 0157 : H7 strain B2387이 분비하는 SLT-II가 gnotobiotic자돈에서의 뇌혈관 병변을 일으키는 pathogenesis에 관해서 실험을 했다. 제왕절개 수술로 태어난 자돈들을 두 그룹으로 나누어서, 한 그룹에는 SLT-II 중화항체를 포함한 혈청을 구강을 통해서 수동면역을 시키고, 또다른 한 그룹에는 SLT-II 중화항체가 포함되어 있지 않은 혈청을 구강을 통해서 수동면역시켰다. 24시간후 두 그룹 모두에게 SLT-II producing Escherichia coli O157 : H7 strain B2387를 구강으로 접종했다. SLT-II 중화항체가 포함되어 있지 않은 혈청으로 수동면역시킨 그룹의 자돈들은 설사와 맹결장염, 신경증상, 뇌혈관병변을 일으키고, plasma의 prostacyclin의 level이 증가했다. 하지만 SLT-II 중화항체가 포함되어 있는 혈청으로 수동면역시킨 그룹의 자돈들은 설사와 맹결장염은 유발했지만, 신경증상과 뇌혈관병변은 관찰되지 않았고, prostacyclin의 level도 증가하지 않았다. 이런 실험결과는 SLT-II 중화항체는 뇌혈관병변은 방어하지만 맹결장염은 방어하지 못한다는 의미를 나타내며, prostacylin의 증가는 뇌혈관의 endothelium의 병변을 의미한다.

• Proceedings of the Korea Contents Association Conference
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• 2016.05a
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• pp.423-424
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• 2016

본 연구는 30대, 40대 남성 근로자의 심뇌혈관질환 인식, 예방에 대한 태도, 건강행위 간의 관계를 알아보고, 건강행위에 미치는 영향요인을 파악하여 30,40대 남성 근로자의 건강행위를 증진키기 위한 기초 자료를 제공하기 위하여 시도되었다. 연구대상자는 G도 J, S시에 소재한 회사에 근무하는 30대, 40대 남성 근로자를 대상으로 하였으며, 자료 수집은 심혈관질환 인식, 뇌혈관질환 인식, 예방에 대한 태도, 건강행위 도구를 통하여 설문 조사하였다. 자료 분석은 SPSS Win 21.0 프로그램을 이용하여 분석하였다. 연구결과 대상자의 평균 평점은 심혈관질환 인식 정도는 17.99점, 뇌혈관질환 인식 정도는 5.21점, 예방에 대한 태도는 3.95점, 건강행위 정도는 2.82점으로 나타났다. 대상자의 심혈관질환 인식, 뇌혈관질환 인식, 예방에 대한 태도는 건강행위와 양의 상관관계가 있는 것으로 나타났다. 대상자의 건강행위에 영향을 미치는 요인으로 결혼상태, 심혈관질환 인식 순이었으며, 전체 설명력은 14.6%이었다. 본 연구를 바탕으로 심뇌혈관질환 예방을 위한 건강행위의 교육적 시사점과 후속연구에 대한 제언을 하였다.