• Sleep Medicine and Psychophysiology
• /
• v.8 no.2
• /
• pp.121-128
• /
• 2001

Objectives: In narcoleptic patients diagnosed with ICSD (international classification of sleep disorders, 1990) criteria, nocturnal polysomnography, and MSLT (multiple sleep latency test), we tried to find characteristic features of quantitative electroencephalography (QEEG) in a wakeful state. Methods: We compared eight drug-free narcoleptic patients with sex- and age-matched normal controls, using computerized electroencephalographic mapping technique and spectral analysis. Absolute power, relative power, interhemispheric asymmetry, interhemispheric and intrahemispheric coherence, and mean frequency in each frequency band (delta, theta, alpha and beta) were measured and analyzed. Results: Compared with normal controls, narcoleptic patients showed decrease in monopolar interhemispheric coherence of alpha frequency bands in occipital ($O_1/O_2$), parietal ($P_3/P_4$), and temporal ($T_5/T_6$) areas and beta frequency band in the occipital ($O_1/O_2$) area. Monopolar intrahemispheric coherences of alpha frequency bands in left hemispheric areas ($T_3/T_5$, $C_3/P_3$ & $F_3/O_1$) decreased. Decrease of monopolar interhemispheric asymmetry of delta frequency band in the occipital ($O_1/O_2$) area was also noted. The monopolar absolute powers of beta frequency bands decreased in occipital ($O_2,\;O_z$) areas. Conclusion: Decreases in coherences of narcoleptic patients compared with normal controls may indicate fewer posterior neocortical interhemispheric neuronal connections, and fewer left intrahemispheric neuronal connections than normal controls in a wakeful state. Therefore, we suggest that abnormal neurophysiological sites of narcolepsy may involve complex areas such as neocortex and subcortex as well as the brainstem.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
• /
• 1998.04a
• /
• pp.81-88
• /
• 1998

두 문자열의 동일성 판단과 뇌파와의 관계가 탐색되었다. 피험자들은 컴퓨터의 화면에 나타나는 두 문자열의 동일성 여부를 판단하여 반응 키를 누르는 과제를 수행하였으며, 이화 동시에 피험자들의 뇌파가 기록되었다. 긍정 반응과 부정 반응 시의 뇌파를 비교한 결과, 좌측 전두엽 부위의 theta파, slow alpha파, fast alpha파 그리고 우측 전두엽 부위의 theta파 그리고 우측 전두엽 부위\ulcorner theta파 등이 긍부정 반응에 따라서 유의한 차이를 보였다.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
• /
• 2000.04a
• /
• pp.91-96
• /
• 2000

본 연구는 이러한 뇌파 바이오피드백 원리를 적용하여 뇌파를 유도하고 유도된 상태에 대한 피드백을 제공함으로써 사용자 스스로 자신의 뇌파 상태를 조절하도록 하는 장치로 개발된 Q0jump 시스템의 효과성을 밝히고자 하였다. 연구 방법에 있어서 뇌파 측정 장비와 Q-jump를 동시에 측정함으로써 Q-jump 시스템의 타당성을 검증하였으며, 또한 뇌파유도 프로그램을 사용하여 그 효과성을 입증하려 했다. 그 결과 Q-jump 시스템과 뇌파 측정장비에서 얻어진 결과가 유의한 상관을 가짐을 보았다. 상대적 출현량에 있어서 뇌파 유도프로그램을 사용했을 때, 전두엽 부분에서 slow alpha 는 유의한 증가를, fast beta는 유의한 감소를 나타냈다. 후속 연구에 있어서는 통제집단을 이용한 보다 면밀한 검증 연구가 필요하다.

• Clinical and Experimental Pediatrics
• /
• v.51 no.8
• /
• pp.861-867
• /
• 2008

Purpose : We carried out this study to determine if there is any difference in the occurrence rate of the epileptiform discharge between awake EEG and sleep EEG and if there are any factors influencing on the occurrence rate of EEG. Methods : This study included 178 epileptic children who had visited neurology clinic of the department of pediatrics, Pusan National University Hospital from July 2005 to July 2006. The medical and EEG records of these children who had had both awake EEG and sleep EEG were reviewed. We analysed the occurrence rate of the epileptiform discharge between awake EEG and sleep EEG. We investigated the related clinical factors which included sex, seizure types, underlying causes, age at first seizure, antiepileptic drug (AED) medication, age at recording, and background activity. Results : Among 178 epileptic children, 91 patients (51.1%) showed epileptiform discharge in awake or sleep states, 10 patients (11.0%) abnormal only in awake, 40 patients (44.0%) abnormal only in sleep, 41 patients (45.0%) abnormal in both awake EEG and sleep EEG. The occurrence rate of sleep EEG was 81 of 178 patients (45.5%) which was more than that of the awake EEG (28.7%) (P<0.001). The occurrence rate of sleep EEG is more than that of the awake EEG regardless of sex and underlying causes. But there is no significant difference from awake EEG and sleep EEG in finding the epileptiform discharge in the patient with generalized seizure, younger than 5 years old at first seizure, younger than 10 years old at recording, no antiepileptic medication, and abnormal background activity. Conclusion : The sleep EEG is thought to be more helpful in the diagnosis of childhood epilepsy.

• Journal of the Korean Society for Library and Information Science
• /
• v.49 no.1
• /
• pp.443-464
• /
• 2015

This study examined the feasibility of using EEG signals and ERP P3b for extracting video key-frames based on users' cognitive responses. Twenty participants were used to collect EEG signals. This research found that the average amplitude of right parietal lobe is higher than that of left parietal lobe when relevant images were shown to participants; there is a significant difference between the average amplitudes of both parietal lobes. On the other hand, the average amplitude of left parietal lobe in the case of non-relevant images is lower than that in the case of relevant images. Moreover, there is no significant difference between the average amplitudes of both parietal lobes in the case of non-relevant images. Additionally, the latency of MGFP1 and channel coherence can be also used as criteria to extract key-frames.

• Clinical and Experimental Pediatrics
• /
• v.51 no.3
• /
• pp.286-292
• /
• 2008

Purpose : We performed EEG and PET on children with epilepsy concomitantly in order to evaluate the effects of epileptiform and non-epileptiform discharge of EEG on glucose metabolism. Methods : Seventy three children with epilepsy who had PET and EEG simultaneously were included in our study. The subjects were classified in two ways: (1) based on the frequency of epileptiform discharge and (2) the severity of non-epileptiform discharge. We evaluated the clinical aspects of their seizures, the severity of focal slow waves during the interictal period with the frequency of spikes or sharp waves in order to compare with the PET results. Results : The subjects were divided by the frequency of epileptiform discharge, with 13 in the no/rare group, 7 in the occasional group, and 53 children in the frequent group. The concordant rates with PET in each group were 0%, 42.9%, and 67.9%, respectively, showing high correlations with the frequency of epileptiform discharge (P<0.05, r=0.491). The subjects as divided by the severity of non-epileptiform discharge were 15 in the no group, 25 in the infrequent group, 17 in the intermediate group, and 16 in the continuous group. The concurrence rates with PET for each group were 13.3%, 52.0%, 64.7%, and 68.8%, respectively, also showing a high correlation with the severity of non-epileptiform discharge (P<0.05, r= 0.365). Conclusion : Epileptiform discharge and non-epileptiform discharge in EEG showed a certain association with hypometabolism in PET. We recommend EEG to reduce false lateralization and to localize lesions in cases of high frequency and severity.

• The Journal of the Korea institute of electronic communication sciences
• /
• v.13 no.2
• /
• pp.481-486
• /
• 2018

In this paper, we aimed to analysis EEG signals related to the relativity between musical stimuli and human brain activity for the arithmetical calculation and present the experimental results. We use two kinds of musical stimuli, one is a sedative tendency music and the other is a stimulative tendency music. The SMR wave and Mid-beta wave are analyzed because of the concentration. In our results, the sedative tendency music is not more interfere with human brain activity for the arithmetical calculations than the stimulative tendency music.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.16 no.6
• /
• pp.3760-3768
• /
• 2015

This study was to examine the correlation of Personality and EEG. Personality test and EEG of the 40 team leader of a business enterprise were carried out at the same time and the correlation of test results were analyzed. Personality test was done by Big 5 and brain waves were measured by 2-Channel EEG System at Fp1 and Fp2. The analysis showed a positive correlation between the Big 5 agreeableness and SRQ(Self Regulation Quotient) relaxation status which is related with alpha rhythm, and showed a negative correlation between the Big 5 openness and SRQ concentration status which is related with low_beta rhythm. It means that the personality is closely correlated with human brain cortex activation and can be checked by brainwave analysis.

• Korean Journal of Biological Psychiatry
• /
• v.21 no.4
• /
• pp.151-160
• /
• 2014

Objectives Prenatal testosterone is known to influence both cerebral laterality and 2nd to 4th digit ratio (2D : 4D). Epigenetic changes are thought to play some role in it. We studied sex-related differences between 2D : 4D and cerebral laterality in patients with schizophrenia and controls to examine the effects of prenatal testosterone in the development of schizophrenia. Methods Forty one men (18 schizophrenic patients and 23 controls) and 40 women (17 schizophrenic patients and 23 controls) were recruited from one psychiatric hospital in Korea. The 2D : 4D and electroencephalographic (EEG) coherence in 19 channels (66 pairs of interhemispheric coherence and 54 pairs of intrahemispheric coherence) were measured. The sex-related statistical analyses between 2D : 4D and EEG coherence in controls and patients with schizophrenia were performed using multiple regression. Results In male patients, the relationship between 2D : 4D and right intrahemispheric EEG coherence showed mainly positive correlation in delta and theta frequency bands, while it showed negative correlation in male controls. In female patients, the relationship between 2D : 4D and interhemispheric EEG coherence showed stronger positive correlation in alpha and beta frequency bands, while it showed weaker positive correlation in female controls. Conclusions Low prenatal testosterone may play certain roles in altered correlation between 2D : 4D and cerebral laterality in schizophrenia and the development of schizophrenia by epigenetic mechanism.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
• /
• 1998.11a
• /
• pp.158-162
• /
• 1998

향에 의해 유발되는 감성에 대한 중추신경계 및 자율신경계의 반응의 변화를 측정하기 위해 안정시키는 향과 각성시키는 향을 사용하여 주관적 평가와 동시에 시행하였다. 안정시키는 향으로 1% Lavendar 향을 사용하였고, 각성시키는 향으로 0.8% Jasmin 향을 사용하였으며, 안정상태를 향자극 전후에 측정하여 대조군으로 사용하였다. 중추신경계의 지표로 뇌파측정을 하였고 뇌파의 전극은 international 10-20 system에서 4 채널을 사용하였으며, 자율신경계의 지표로는 심전도, heart rate, 피부저항, 피부온도를 기록하였다. 뇌파의 분석은 Fast Fourier Transform analysis의 power spectra로 하였고, 그 frequency bands는 theta(4-8Hz), alpha(8-l3Hz), beta(14-30Hz)로 하였다 또한 심전도를 이용하여 심전도 상의 연속적인 R-R peak간 시간간격을 시계열 데이터로 재구성한 Heart rate variability 분석도 하였다. HRV 분석을 보다 정확히 할 수 있도록 호흡이 심전도에 미치는 영향을 제거하기 위하여 호흡을 분당 20회로 일정하게 하였다 생체신호 측정과 동시에 실시한 주관적 검사에서 lavendar 향은 친숙하게, jasmin 향은 활기차고 상쾌하고 유쾌하게 평가되었다. 뇌파 분석에서 lavendar 향을 주었을 때 theta의 증가 양상을 보였으며, Jasmin 향을 주었을 때는 모든 채널에서 beta 파의 증가 양상을 보였다. 또한 HRV 분석 결과 부교삼신경의 활동성이 부각되는 HF/LF의 값이 lavendar에서는 대조 자극보다 높게 나타났으며, jasmin에서는 대조자극보다 낮은 값이 나타나는 경향을 보였다. 결론적으로 안정과 각성의 후각 자극으로 인한 감성의 변화를 뇌파와 자율신경계 등의 생체지표로 관찰할 수 있었다.정하는 감성요인의 차이를 알 수 있었으며 또한 essential oil에서는 성별 차이가 없는데 반해 페르몬 향의 경우 성별의 차이를 나타내었다.. 방법을 타액과 혈청내 testosterone 농도 측정에 응용하여 RIA의 결과와 비교하여 본 바 상관관계가 타액에서 r=0.969, 혈청에서 r=0.990으로 두 결과가 잘 일치하였다. 본 실험에서 측정된 한국인 여성의 타액내 testosterone농도는 107.7$\pm$12.0 pmol／l이었고, 남성의 타액내 농도는 274.2$\pm$22.1 pmol／l이었다. 이상의 결과로 보아 본 연구에서 정립된 EIA 방법은 RIA를 대신하여 소규모의 실험실에서도 활용할 수 있을 것으로 사려된다.또한 상실기 이후 배아에서 합성되며, 발생시기에 따라 그 영향이 다르고 팽창과 부화에 관여하는 것으로 사료된다. 더욱이, 조선의 ${\ulcorner}$구성교육${\lrcorner}$이 조선총독부의 관리하에서 실행되었다는 것을, 당시의 사범학교를 중심으로 한 교육조직을 기술한 문헌에 의해 규명시켰다.nd of letter design which represents -natural objects and was popular at the time of Yukjo Dynasty, and there are some documents of that period left both in Japan and Korea. "Hyojedo" in Korea is supposed to have been influenced by the letter design. Asite- is also considered to have been "Japanese Letter Jobcheso." Therefore, the purpose of this study is to loo