• Journal of the Korean Society of Radiology
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• v.84 no.4
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• pp.964-969
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• 2023

Guillain-Barré syndrome (GBS) is an immune-mediated demyelinating polyneuropathy characterized by progressive, ascending, and symmetrical paralysis. It is known to be triggered by an antecedent infection or vaccination. Recently, GBS development following coronavirus disease 2019 (COVID-19) vaccination has been reported. Cranial neuropathies in typical GBS patients usually involve the facial and the lower cranial nerves (from IX to XII). We report a rare case of multiple cranial neuropathies involving trigeminal, abducens, and facial nerves in a patient who developed GBS following COVID-19 vaccination on the basis of obvious MRI features.

• The Journal of the Society of Stroke on Korean Medicine
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• v.19 no.1
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• pp.55-62
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• 2018

A patient with right upper limb weakness was diagnosed with idiopathic polyneuropathy and received a series of Korean Medicine including acupuncture, electroacupuncture, bee venom acupuncture, and administration of herbal medicine BacJung-hwan for 17 days of hospitalization period. The progression of the weakness was measured by Hand grip tester, neuralgia and numbness were measured by the NRS(Numerical Rating Scale) scores. After treatment, the right grip strength improved from 12kg to 35kg and the right upper limb neuralgia of the NRS5 was improved to NRS2. The present case study suggests that the potential effects of Korean Medicine treatment for idiopathic polyneuropathy.

• The Monthly Diabetes
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• s.259
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• pp.26-28
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• 2011

당뇨병은 주로 미세혈관계에 문제를 일으키는 대표적인 전신 질환으로 눈에 영향을 끼치는 질환 중에서는 가장 중요한 질환이라 할 수 있다. 당뇨병으로 인해 발생할 수 있는 눈의 합병증에는 대표적으로 당뇨망막병증이 있으며 백내장, 녹내장, 뇌신경 마비, 각막 질환 등이 있다.

• Annals of Clinical Neurophysiology
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• v.6 no.1
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• pp.48-51
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• 2004

The occurrence of polyneuropathy in association with monoclonal gammopathy of undetermined significance (MGUS) is quite common. However, reports of MGUS associated cranial neuropathies are rare. A 63 year-old women was presented with diplopia and swallowing difficulty. Neurological examination showed limitation of abduction of right eye, right peripheral facial palsy, decreased hearing and gag reflex, left side deviation of uvula, and decreased DTR. Sensorimotor polyneuropathy were observed with elctrophysiological studies. Protein and immunoelectrophoresis revealed IgG ${\kappa}$monoclonal gammopathy. She was treated with intravenous immunoglobulin and steroid, and her symptoms and signs were improved. This case suggested that she had sensorimotor polyneuropathy and multiple cranial neuropathies associated with IgG ${\kappa}$MGUS.

• Journal of the Korean neurological association
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• v.35 no.4
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• pp.244-246
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• 2017

• Journal of Acupuncture Research
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• v.25 no.1
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• pp.211-219
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• 2008

목적 : 전통적으로 태충($LR_3$)과 양릉천($GB_{34}$)은 운동기능과 관련된 질환에 사용되어 왔다. 우리는 두뇌에 신경독을 주입하여 파킨슨병 쥐모델을 제작하였고, 쥐는 운동기능이 손상되고 도파민성 신경세포가 선택적으로 소멸하였다. 병증 모델 쥐에게 태충과 양릉천에 자침한 결과 운동기능이 개선되고 신경세포보호효과가 나타남을 관찰한 바 있다. 이에 실제로 태충과 양릉천에 자침하여 운동기능과 관련된 추체외로 영역에서 신경의 활성화가 나타나는지를 fMRI를 통하여 관찰하였다. 방법 : 자침은 수기침을 선택하였으며, 혈위는 (1) 태충, (2) 양릉천, (3) 태충+양릉천의 세군데를 설정하였고, 자침에 대한 대조자극으로 피부자극을 채택하였다. fMRI 스캐너는 3T를 사용하였고 뇌신경 활성화의 신호는 BOLD(blood-oxygen-level dependant)를 관찰하였다. 두뇌에서 관찰부위는 중뇌를 중심으로 추체외로로 한정하였다. 결과 : 태충에 자침하였을 때 두뇌의 substantia nigra, subthalamic nucleus, red nucleus, pons 등이 활성화 되었다. 양릉천에 자침하였을 때 substantia nigra, subthalamic nucleus, caudate nucleus, thalamus가 활성화 되었다. 태충과 양릉천에 동시에 자침하였을 때는 substantia nigra, subthalamic nucleus, red nucleus, globus pallidus가 활성화되었다. 대조자극에 의해서는 위의 영역들이 활성화되지 않았다. 결론 : 태충, 양릉천, 태충+양릉천 자극은 대뇌에서 추체외로 영역을 활성화시키며 특히 substantia nigra의 활성화는 파킨슨병과 같은 질환의 조절가능성을 시사한다.

• The Journal of Internal Korean Medicine
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• v.42 no.5
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• pp.958-966
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• 2021

Objective: This study investigated the effectiveness of bee venom acupuncture for a diabetic neuropathy patient. Methods: A diabetic neuropathy patient received twenty-one bee venom acupuncture treatments for a total of 99 days. The Neuropathy Pain Scale (NPS) was used to evaluate the weekly peak pain during the treatment period. Results: After the treatments, the NPS scores improved, and the frequencies of peak pain decreased. Conclusions: This clinical case indicates that bee venom acupuncture combined with Korean medicine may be effective for treating diabetic neuropathy patients.

• Journal of Oral Medicine and Pain
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• v.34 no.2
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• pp.197-205
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• 2009

The purpose of this study was to investigate the treatment pattern of patients with neuropathic pain (NeP) in Korea through computerized database of Health Insurance Review and Assessment Service (HIRAS) over three years' period from 2003 to 2005. The results showed that the numbers of treatment visits were the highest for diabetic neuropathy (DN), followed by postherpetic neuralgia (PHN) and trigeminal neuralgia (TN) in order. Top 3 specialties for treatment visits due to NeP conditions were neurology, neurosurgery and anesthesiology. While cost of a treatment visit was higher in anesthesiology and emergency clinics compared to other clinics, there was a tendency to increase costs for visits to clinics of rehabilitation medicine and family medicine over the three years. Cost of dental visits was relatively high for TN, atypical facial pain (AFP) and atypical odontalgia (AO). Surgeries frequently applied to patients with NeP were sympathetic plexus or ganglion block, block of peripheral branch of spinal nerve and cranial nerve or its peripheral branch block. Most common prescribed medication were anticonvulsants, anti-inflammatory analgesics and anti-psychotic drugs while anti-inflammatory analgesics were overwhelmingly frequently prescribed for AO and glossodynia. Based on the results of this study, NeP disorders more relevant to dentists were AO, TN and AFP, TN of which seems to be the most important in terms of patients' number and cost for treatment visits. This indicates that dentists, especially oral medicine specialists should actively participate in management of TN, AO and AFP and share relevant information with patients and community.