• The Journal of the Korea Contents Association
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• v.16 no.1
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• pp.295-307
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• 2016

The purpose of this study was to examine the awareness and knowledge of school organizational members about peridontal diseases, their belief in the diseases, attitude and periodontal health in an effort to provide some information on how to ensure successful oral health education and incremental dental care. The subjects in this study were the selected patients who visited school dental clinics. Their ideas of periodontal diseases and periodontal health were analyzed to determine the influential factors. They got a mean of 2.77 in awareness of the epidemiologic characteristics of periodontal diseases, 2.97 in knowledge on the initial symptoms of gingivitis, 2.90 in awareness of the causes of periodontal diseases, 2.95 in awareness of the prevention and treatment of peridontal diseases, and 3.04 in belief in periodontal diseases and attitude. Thus, they had a good understanding and knowledge of periodontal diseases, and they had the right belief and the right attitude as well. They scored relatively lower in several items of periodontal diseases: awareness of tooth loss caused by aging, awareness of the relationship of food to the prevention and occurrence of periodontal diseases, the relationship between toothbrushing time and gingival health, the right toothbrushing method and the right way of dental care.

• Korean Journal of Adult Nursing
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• v.29 no.1
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• pp.41-50
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• 2017

Purpose: The purpose of this study was to identify and compare the factors influencing attitude toward one's own aging among Korean middle-aged adults and the elderly. Methods: A cross sectional study was performed with a total sample of 70 middle-aged adults and 64 elderly reside in two metropolitan areas. Data were collected from August 2015 to November 2015 using the Perceived Health Status Scale, the Health Locus of Control Scale and the Attitude Toward own Aging (ATOA) Scale. The statistics used include percentage, t-test, Pearson's correlation coefficient, and multiple regression. Results: Mean age for each age group were about 52 and 76 years old for middle-aged adults and the elderly respectively. A considerable proportion of all participants reported a negative attitude toward aging. Perceived health status was the common factor influencing attitude toward one's own aging in both age groups. Middle-aged adults identified presence of chronic illness and internal health locus of control as important factors. In contrast, the elderly reported that education and others-dependent health locus of control such as powerful others had a significant impact on ATOA. Each regression model explained 31% and 55% of the total variance of ATOA among middle-aged adults and among the elderly. Conclusion: Both middle-aged adults and the elderly with low perceived health status are at risk of negative ATOA's. The type health locus of control need to be identified and utilized based on individuals' tendency to improve positive ATOA. That is, middle-aged adults might need reinforcement of their self-will whereas the elderly might need enhancement of social support and network of family and healthcare providers.

• Journal of muscle and joint health
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• v.29 no.3
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• pp.218-227
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• 2022

Purpose: This study aimed to describe the current level of physical activity (PA) and to explore the relationships between self-efficacy for PA, perceived health status (PHS), attitudes toward aging, ego-integrity and PA in community-dwelling older Koreans. Methods: A total of 164 participants were recruited from community centers, churches, and senior welfare centers in Korea. With questionnaires, a survey was conducted from June 3rd to 22th, 2016. Data were analyzed with descriptive statistics, independent t-test, one-way ANOVA and Pearson's correlation coefficient using SPSS/WIN 22.0 program. Results: The mean amount of total PA was 5,295.33±6,272.38 MET/min/week. The number of subjects engaged in vigorous, moderate, and low-intensity activities were 87 (53.0%), 45 (27.4%), and 32 (19.5%), respectively. Overall, physical activities were different according to the presence of spouse (t=-2.79, p=.006) and the presence of housemate (t=2.03, p=.044). The mean scores of self-efficacy for PA, PHS, attitudes towards aging, and ego-integrity were 17.16±4.45, 9.00±2.41, 68.12±9.28 and 51.62±7.59, respectively. There were significant positive correlations between overall PA and self-efficacy for PA (r=.34, p<.001), PHS (r=.23, p=.003), attitudes towards aging (r=.26, p=.001). Conclusion: Specific programs to promote physical activities in addition to continuous education for improving self-efficacy for PA, PHS, and attitudes towards aging in community-dwelling older adults are needed.

• Korean Journal of Health Education and Promotion
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• v.32 no.5
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• pp.33-42
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• 2015

Objectives: It has been found that health promotion interventions are effective to decrease morbidity among older people. The acceptability of interventions are, however, still troublesome for achievement of efficacy of health promotion interventions. The current study examines the effects of age identity and attitude toward aging on the use of health promotion programs among older people. Methods: Data from the Survey of Living Conditions of Korean Older Persons were used. Logistic regression models were tested using a nationally representative sample of 9,461 community-dwelling older individuals who are 65 years old and over. Results: Older individuals who have younger age identity and more negative attitude toward aging were less likely to use health promotion programs, after adjusting the effects of other predisposing, enabling, and need factors such as demographic characteristics and personal health characteristics. Conclusions: Strategies for mitigating the possible effects of age identity and attitude toward aging on the acceptability of health promotion programs are also discussed.

• Journal of Life Science
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• v.27 no.12
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• pp.1515-1522
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• 2017

Most people have a desire to live longer. According to ancient Chinese and Korean mythology, Dongfang Shuo (Dongbang Sahk) lived for 18,000 years. According to a WHO report, the average longevity of humans has extended from 50-odd years in the 1960s to 75-85 years in 2016. Parabiosis, the joining to circulatory systems of two animals, was described as early as the 1860s. It provides a powerful experimental model to investigate the effects of one animal on its partner animal in vivo. Research on reverse aging is an immensely popular in parabiosis studies. In this review, the origin of the parabiosis model and important historical findings based on parabiosis models are presented. Surprising and debated discoveries in aging research are also introduced. Using heterochronic parabiosis of connecting circulatory systems of a young mouse and old mouse, various groups claim to have identified a reverse aging factor, growth differentiation factor 11 (GDF11), which was significantly reduced in blood of old mice. Although the potential existence of any one factor or factors that could reverse aging remains to be confirmed, studies have shown that the parabiosis model is powerful enough to detect reverse aging factors.

• Journal of Life Science
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• v.29 no.10
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• pp.1071-1079
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• 2019

In this study, we investigated the antioxidant and anti-aging activities of Schisandra chinensis seed fractions by adding them to UVB-irradiated HaCaT cells and analyzing the suppression of matrix metalloproteinases (MMPs). An electron-donating assay, ABTS radical scavenging assay, and hydrogen peroxide scavenging assay showed that the ethyl acetate fraction of S. chinensis seed (SCEAf) has scavenging activities. A collagenase inhibition activity assay showed that SCEAf had inhibitory effects of over 92.3% at $500{\mu}g/ml$ concentration. An MTT assay was performed to determine the cytotoxicity of SCEAf in HaCaT cells and the results showed that SCEAf increased cellular viability in a concentration-dependent manner. In addition, SCEAf was found to increase the viability of cells irradiatged by UVB $50mJ/cm^2$. To examine the anti-aging effects of SCEAf on HaCaT cells irradiated with UVB $50mJ/cm^2$, the expression of MMP-1 and -3 was analyzed by Western blotting and reverse-transcription polymerase chain reaction. The results showed that MMP-1 and -3 proteins and mRNA levels were downregulated in a concentration-dependent manner in response to SCEAf. These results suggest that SCEAf can prevent aging and alleviate aging symptoms by inhibiting collagenase activity in skin keratinocytes damaged by UVB. Therefore, S. chinensis seeds may have the potential for use as functional ingredients with anti-aging effects in the cosmetic and food industries.

• Journal of Korea Foresty Energy
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• v.21 no.2
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• pp.25-33
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• 2002

One of the critical problems to preserve books and documents in libraries and archives is the deterioration. Some of previous results showed that the major cause of paper deterioration was the acid-catalyzed hydrolysis of the cellulose in paper fibres and aging rate of acidic paper was faster than that of alkaline paper. Therefore, It is necessary to remove the acid in the paper for reducing the rate of paper deterioration. It has been reported to extend the useful life of acidic paper by three to five times. Recently, It has been recognized the need for an effective method of deacidifying large quantities of books and document. However, in the previous many reports little attention was paid to the effect of paper additives. In this paper, We carried out experiment about the effect of additives on paper aging and the effect of deacidification by the gaseous ethanolamines (monoehtanolamine, diethanolamine, triehtanolamine). In result, it was found that the strength of aging was in the order of the alum＋rosin＞alum ＞AKD＞ control and the rate of deacidification was in the order of the monoethanolamine＞diethanolamine＞triethanolamine. The treatment with the gaseous ethanolamines caused decreasing of brightness and dropping of fold endurances. However, deacidification by combination treatment of the various gaseous ehtnaolamines prevented from decreasing of brightness and dropping of folding endurances.

• Journal of Life Science
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• v.28 no.3
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• pp.331-338
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• 2018

Melanin is a polymer substance that plays an important role in the determination of hair growth and skin color in vivo. However, melanin, which is over-produced by reactive oxygen species, is known to cause stains, freckles, and hypercholesterolemia, which are associated with aging. Previous studies have shown that polyphosphate, one of the components of Rhynchosia Nulubilis, inhibits skin aging induced by ultraviolet rays. The aim of this study is to investigate the direct effect of Rhynchosia Nulubilis ethanolic extract (RNEE) on melanin synthesis. In this study, RNEE showed no antioxidative effects on scavenging activity of DPPH radical in addition to reducing power. The cytotoxicity of RNEE was increased in a dose-dependent manner in an MTT assay. In addition, RNEE increased tyrosinase activity and melanin synthesis in DOPA-oxidation experiments. RNEE did not promote the conversion L-DOPA into melanin in live cells, but melanin production was promoted in the RNEE-treated group after H2O2 pretreatment compared to the control group in which melanin production was reduced by treatment with H2O2. In addition, RNEE increased the expression level of tyrosinase related protein-2 (TRP-2) and increased the expression level of tyrosinase related protein-1 (TRP-1) at a concentration of $16{\mu}g/ml$. In particular, it was found that RNEE increased the expression level of SOD-3, by which superoxide anion is converted to hydrogen peroxide, higher than the control and ${\alpha}$-MSH used as a positive control at a concentration of more than $16{\mu}g/ml$. The results suggest that RNEE can induce melanogenesis related to black hair.

• Korean Journal of Food Science and Technology
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• v.50 no.6
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• pp.653-659
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• 2018

In this study, we investigated the antioxidant activities and anti-aging efficacy in terms of suppression of matrix metalloproteinases (MMPs) in UVB-irradiated HaCaT cells by adding the ethanol extracts of Josaengheogchal (JE) and Shintoheug rice (SRE). In the electron-donating ability and ABTS radical-scavenging assays, we observed that both JE and SRE had scavenging activities and in a collagenase inhibition assay, both extracts showed inhibition effects of over 73% at $1,000{\mu}g/mL$ concentration. The expression of MMP-1 and -3, when the extracts were treated with UVB $50mJ/cm^2$, irradiated human HaCaT keratinocytes, was analyzed by western blotting and reverse-transcription polymerase chain reaction (RT-PCR). The results showed that MMP-1 and -3 proteins and mRNAs were downregulated in a concentration-dependent manner in response to both extracts. Therefore, we expect that these compounds have a potential for the use as functional ingredients with anti-aging effects in the cosmetic and food industries.

• Journal of Physiology & Pathology in Korean Medicine
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• v.34 no.6
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• pp.279-284
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• 2020

The theory of "eccentric diseases are generally due to phlegm (怪病多屬痰)" means that phlegm is a major cause for intractable diseases including cerebrovascular accident, depression, insanity, and shock from strange things or evil sprint. It has been a key foundation for the diagnosis and treatment of phlegm in traditional Korean medicine. However, the origin of the theory is not clear and controversial. In this study, we critically reviewed the origin and developing process of the theory in the viewpoints of philology and pathology in Korean medicine. Wang Yin-Jun (王隱 君) did not claim that eccentric diseases are generally due to phlegm in Taidingyangshengzhu-lun (泰定養生主論). The miscitation by following medical literature caused the misunderstanding in the meaning of Taidingyangshengzhu-lun, that phlegm can cause variable symptoms and signs. In the Ming dynasty, some poor medical doctors had tended to diagnose any difficult case as phlegm syndrome and to use Kuntan-huan (滾痰丸) as a standard herbal formula for treating phlegm syndrome. However, the tendency to categorize delicate cases easily to phlegm syndrome is not desirable. Besides, the tendency to use Kuntan-huan as a basic formula for the phlegm syndrome might cause diverse and severe adverse effects. Thus, we cannot accept the theory of eccentric diseases is generally due to phlegm without a doubt. In conclusion, this theory might be a valuable aphorism in terms of considering the possibility of the secondary pathologic factors including phlegm and blood stasis which should be considered first in case of intractable diseases.