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CLINICAL MANAGEMENT OF ECTODERMAL DYSPLASIA : A CASE REPORT (외배엽 이형성증 환자의 임상적 치험례)

  • Oh, So-Hee;Kwon, Soon-Won;Kim, Jong-Soo;Kim, Yong-Kee;Lim, Hun-Song
    • Journal of the korean academy of Pediatric Dentistry
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    • v.27 no.2
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    • pp.222-228
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    • 2000
  • Ectodermal dysplasia is a hereditary disease characterized by a congenital dysplasia of one or more ectodermal structures and their accessory appendages. At least 120 subtypes of ectodermal dysplasia have been reported. The disease is usually transmitted as an X-linked recessive trait in which the gene is carried by the female and manifested in the male. Hypohidrotic ectodermal dysplasia is manifested as a triad of defects that include hypohidrosis, hypotrichosis and hypodontia. The characteristic facial features consist of asteatosis, onchodysplasia, sparse and fine blond hair, prominent forehead, a depressed nasal bridge, thick everted lips. The patient may suffer from dry skin, hyperthermia and unexplained high fever as a result of the deficiency of sweat glands. This case report presents detailed procedures of rehabilitating functional and esthetic defect of a 6-year-old boy with hypohidrotic ectodermal dysplasia along with the review of relevant literatures.

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LEUKOCYTE ADHESION DEFICIENCY TYPE I: CASE REPORT (Leukocyte adhesion deficiency type I 환자의 치험례)

  • Yoon, Eun-Young;Lee, Nan-Young;Lee, Sang-Ho
    • Journal of the korean academy of Pediatric Dentistry
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    • v.36 no.4
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    • pp.586-590
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    • 2009
  • Leukocyte adhesion deficiency is rare inherited defect on phagocytic function resulting lack of leukocyte cell surface expression of $\beta2$ integrin molecule that are essential for leukocyte adhesion to endothelial cells and chemotaxis. Clinical features of patients with leukocyte adhesion deficiency type I include recurrent necrotic infection of the skin mucous membranes, and intestinal tract with septicemia, and omphalitis arising from delayed umbilical cord separation. Oral manifestations are severe progressive periodontitis with alveolar bone loss, periodontal pockets, and partial and total premature loss of the deciduous and permanent dentitions. We report a case of leukocyte adhesion deficiency type I in a 5-year-old child with severe periodontitis. In order to prevent local and systemic infection, we controlled periodontal disease with periodic oral prophylaxis. Oral swabs and blood cultures were perfomed for suspected infection, so that optimal measures were taken through the use of appropriate antibiotics.

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Effects of Human Plasma Lipid Transfer Protein on the Distribution of Lipids Between Lipoprotein Fractions of Rat Plasma (인체의 혈장에서 분리한 지질전이단백질이 흰쥐의 혈장 Lipoprotein 의 지질분포에 미치는 영향)

  • 최영선
    • Journal of Nutrition and Health
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    • v.19 no.5
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    • pp.296-303
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    • 1986
  • Rat lipoprotein-deficient plasma possessed a lipid tramsfer inhibitory activity when it was added to purified human plasma lipid transfer protien, while it lacked a lipid transfer activity. Incubation of whole rat plasma with partially purified human lipid transfer protein resulted in big changes in lipid distribution of rat plasma lipoproteins. There w was a 4-fold increase in cholesteryl ester(CE) and 4 47 % reduction in triglyceride(TG) in very low density lipoproteins after 2싹lour incubation. In high density lipoprotein $2(HDL_2)$ there was a 9­fold increase in TG and 33 % reduction in CEo HDL3 had 82 % reduction in CE. The result indi­c cates that the absence of the lipid transfer activity in rat plasma can be ascribed not to the inability of rat lipoproteins to serve as substrates but to the lack of 야Ie lipid transfer protein in rat plasma. Th­e erefore, species differences in lipid transfer betwe­e en lipoproteins should be taken into consideration to interpret results of studies on lipoprotein m.eta­b bolism using rats.

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A study on the optimization of manufacturing processes of double wall bellows for dual fuel engine II - Optimization of welding process - (Dual Fuel 엔진용 이중관 벨로우즈 제작 공정의 최적화에 관한 연구 II - 용접공정의 최적화 -)

  • Kim, Pyung-Su;Kim, Jong-Do;Song, Moo-Keun
    • Journal of Advanced Marine Engineering and Technology
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    • v.40 no.6
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    • pp.504-509
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    • 2016
  • Production processes of double wall bellows can be roughly categorized into two steps. In the first step, inner and outer bellows are made of STS316L in austenite stainless steel due to their excellent formability and corrosion resistance. In the second step, the double wall bellows are manufactured using the welding method with both the inner and outer bellows. The microstructure and defects of each weldment are observed to ensure the reliability of bellows since weldment is a highly vulnerable part, which can crack and fracture when bellows are formed or used. In this study, optimum welding conditions were derived from the analysis of microstructure and inspection of weldment of bellows that were produced using various welding procedure. Moreover, the mechanical properties were evaluated through hardness measurement of substrate, weldment and the heat-affected zone.

사이클 화학 기상 증착 시스템에 의해 제조된 다층 무기 박막의 유기 발광 다이오드 박막 봉지

  • Lee, Jun-Hyeok;Min, Seok-Gi;Han, Yeong-Gi;An, Jae-Seok;Choe, Beom-Ho
    • Proceedings of the Korean Vacuum Society Conference
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    • 2014.02a
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    • pp.397.2-397.2
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    • 2014
  • 유기 발광 다이오드 (OLED)의 상용화를 위해 해결해야할 기술적 문제 중하나는 장수명이다. OLED에 적용된 유기물 층은 수분과 산소에 취약하여 소자 수명을 단축하는 요소로 작용하는데, 이를 해결하기 위해 유기물을 보호하며, 유기물 내로 침투되는 수분과 산소를 제어하기 위한 보호 층의 증착이 필수적이다. 필수적이다. 본 연구에서는, 사이클 화학 기상 증착법(C-CVD)을 이용하여 SiN/SiCN/SiN 구조의 무기 박막을 증착하여 유기물 보호층으로서의 적용 가능성을 제시하고자 한다. 이 때 각층의 두께는 각 각 10 nm이다. 증착된 다층 무기 박막은 비정질 상으로 수분 침투 보호막으로서 적당하다. 다층 무기 박막의 수분에 대한 저항성은 칼슘을 이용한 투과도 변화를 이용하여 측정하였다. 칼슘을 이용한 투과도 측정을 위해 고분자 PEN 필름위에 칼슘을 60nm 두께로 증착 시키고, 이어서 무기물인 SiN/SiCN/SiN의 다층 박막을 확산 방지층으로 증착 하였다. 제작된 소자는 온도 $85^{\circ}C$, 상대습도 85%의 가혹 조건에서 시간에 따른 표면 변화 및 투과도의 변화를 측정하였다. SiN/SiCN/SiN 구조를 갖는 무기 박막 층의 투습도는 3000시간까지는 $3.2{\times}10-5g/m/day$를 유지하였다. 이는 OLED 소자의 상용화를 위한 요구 조건에 근접한 값이다. 그러나 투습도는 측정 시간이 6000시간이 지난 후에 급격 증가하는데 이것은 30nm 두께의 SiN/SiCN/SiN의 확산 방지층에 임계 수명이 존재 한다는 것을 의미 한다고 할 수 있다. C-CVD 기술에 의해 제조된 다층 무기 박막 보호 층의 경계면에서 각 층간의 intermixing 현상이 관측되었으며, 이는 무기물 층의 결함과 핀 홀을 통해 내부로 확산 되는 수분의 침투 경로를 효과적으로 제어할 수 있는 방법이다. 본 연구 결과는 유연 기판 상에 제작된 OLED 소자에 적용 가능한 기술로서 소자 수명의 연장 뿐만 아니라 경량화에도 기여할 수 있는 기술이다.

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Basal slip (0001)1/3<1120> dislocation in sapphire ($\alpha$-Al$_2$O$_3$) single crystals Part I : recombination motion (사파이어($\alpha$-Al$_2$O$_3$) 단결정에 있어 basal slip (0001)1/3<1120>전위 Part I : 재결합거동)

  • Yoon, Seog-Young
    • Korean Journal of Materials Research
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    • v.11 no.4
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    • pp.278-282
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    • 2001
  • The recombination motion of Partial dislocations on basal slip (0001) 1/3<1120> in sapphire ($\alpha$-Al$_2$$O_3$) single crystals was investigated using the four-point bending test with the prism plane (1120) samples. These bending experiments were carried but in the temperature range from $1200^{\circ}C$ to $1400^{\circ}C$ at various engineering stresses 90MPa, 120MPa, and 150MPa. During these tests it was shown that an incubation time was needed for basal slip to be activated. The activation energy for the incubation time was 5.6-6.0eV in the temperature range from $1200^{\circ}C$ to $1400^{\circ}C$. The incubation time is believed to be related to recombination of climb dissociated partial dislocations via self-climb. In addition, these activation energies are nearly same as those for oxygen self-diffusion in $Al_2$$O_3$ (approximately 6.3 eV). Thus, the recombination of the two partial dislocations would be possibly controlled by oxygen diffusion on the stacking fault between the partials.

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Proactive Network Optimizer for Critical Applications (크리티컬한 응용을 위한 능동형 네트워크 최적화기)

  • Park, Bongsang;Park, Pangun
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.22 no.9
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    • pp.1250-1256
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    • 2018
  • Recently, wireless networks are becoming an important infrastructure for the critical large-scale applications such as cyber-physical systems and next generation industrial automations. However, the fundamental performance uncertainty of wireless networks may incur the serious instability problem of the overall systems. This paper proposes the proactive network optimizer to guarantee the application demands without any real-time link monitoring information of the networks. In particularly, the proposed proactive optimizer is the cross-layer approach to jointly optimize the routing path and traffic distribution in order to guarantee the performance demand within a maximum k number of link faults. Through the simulations, the proposed proactive network optimizer provides better robustness than the traditional existing reactive networks. Furthermore, the proactive network does not expose to the major weakness of the reactive networks such as the performance degradation due to the erroneous link monitoring information and the network reconfiguration cost.

A Developer Recommendation Technique Based on Topic Model and Social Network (토픽 모델과 소셜 네트워크를 이용한 개발자 추천방법)

  • Yang, Geunseok;Zhang, Tao;Lee, Byungjeong
    • Journal of KIISE:Software and Applications
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    • v.41 no.8
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    • pp.557-568
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    • 2014
  • Recently, software projects have been increasing and getting complex. Due to the large number of submitted bug reports, developers' workload increases. Generally in bug triage process, the triagers assign the bug report to fixer (developer) in order to resolve the bug. However, bug reports have been reassigned to other developers because fixers are not suitable. This is why the triagers did not correctly check and understand the bug report and decide the appropriate developers to fix the bug. This results in increase of developers' time and efforts in software maintenance. To resolve these problems, in this paper, we propose a novel method for developer recommendation based on topic model and social network. First, we build a basis of topic(s) from bug reports. Next, when a new bug report (test data set) comes, we select the most similar topic(s) and extract the participated developers from the topic(s). Finally, by applying social network, we analyze the developers' behavior (comment and commit activity) and recommend the appropriate developers. In this paper we compare our work with related studies through performance experiments on open source projects. The results show that our approach is more effective than other studies in bug triage.

An Analysis for the Adjustment Process of Market Variations by the Formulation of Time tag Structure (시차구조의 설정에 따른 시장변동의 조정과정 분석)

  • 김태호;이청림
    • The Korean Journal of Applied Statistics
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    • v.16 no.1
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    • pp.87-100
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    • 2003
  • Most of statistical data are generated by a set of dynamic, stochastic, and simultaneous relations. An important question is how to specify statistical models so that they are consistent with the dynamic feature of those data. A general hypothesis is that the lagged effect of a change in an explanatory variable is not felt all at once at a single point in time, but The impact is distributed over a number of future points in time. In other words, current control variables are determined by a function that can be reduced to a distributed lag function of past observations. It is possible to explain the relationship between variables in different points of time and to estimate the long-run impacts of a change in a variable on another if time lag series of explanatory variables are incorporated in the model specification. In this study, distributed lag structure is applied to the domestic stock market model to capture the dynamic response of the market by exogenous shocks. The Domestic market is found more responsive to the changes in foreign market factors both in the short and the long run.

Comparison of Growth Mode between GaAs and InAs Self Assembled Nanowire on Si(111) by Molecular Beam Epitaxy

  • Ha, Jae-Du;Park, Dong-U;Kim, Yeong-Heon;Kim, Jong-Su;Kim, Jin-Su;No, Sam-Gyu;Lee, Sang-Jun
    • Proceedings of the Korean Vacuum Society Conference
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    • 2012.02a
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    • pp.325-325
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    • 2012
  • 1차원구속 반도체인 nanowires (NWs)는 전기적, 광학적으로 일반 bulk구조와 다른 특성을 가지고 있어서 현재 많은 연구가 되고 있다. 일반적으로 NWs는 Au 등의 금속 촉매를 이용하여 성장을 하게 되는데 이때 촉매가 오염물로 작용을 해서 결함을 만들어서 bandgap내에 defect level을 형성하게 된다. 본 연구는 Si (111) 기판 위에 GaAs NWs 와 InAs NWs를 촉매를 이용하지 않고 성장 하였다. vapour-liquid-solid (VLS)방법으로 성장하는 GaAs NWs는 Ga의 droplet을 이용하게 되는데 Ga이 Si 기판위에 자연 산화막에 존재하는 핀홀(pinhole)로 이동하여 1차적으로 Ga droplet 형성하고 이후 공급되는 Ga과 As은 SiO2 보다 GaAs와 sticking coefficient 가 좋기 때문에 Ga drolept을 중심으로 빠른 선택적 성장을 하게 되면서 NWs로 성장을 하게 된다. 반면에 InAs NWs를 성장 할 시에 droplet 방법으로 성장을 하게 되면 NWs가 아닌 박막 형태로 성장을 하게 되는데 이것으로 InAs과 GaAs의 $SiO_2$와의 sticking coefficient 의 차이를 추측을 할 수 있다. InAs NWs는 GaAs NWs는 달리 native oxide를 이용하지 않고 InAs 과 Si 사이의 11.5%의 큰 lattice mismatch를 이용한다. 이종의 epitaxy 방법에는 크게 3종류 (Frank-van der Merwe mode, Stranski-Krastanov mode, Volmer-Weber mode)가 있는데 각기 다른 adatom 과 surface의 adhesive force로 나누어지게 된다. 이 중 Volmer-Weber mode epitaxy는 adatom 의 cohesive force가 surface와의 adhesive force보다 큰 경우 성장 되는 방식으로 InAs NWs 는 이 방식을 이용한다. 즉 droplet을 이용하지 않는 vapour-solid (VS) 방법으로 성장을 하였다. 이 때 In 의 migration을 억제하기 위해서 VLS mode 의 GaAs NWs 보다 As의 공급을 10배 이상 하였다. FE-SEM 분석 결과 GaAs NWs는 Ga droplet을 확인 할 수 있었고 InAs NWs는 droplet이 존재하지 않았다. GaAs와 InAs NW는 density와 length가 V/III가 높을수록 증가 하였다.

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