• Proceedings of the KIEE Conference
• /
• 2011.07a
• /
• pp.2037-2038
• /
• 2011

피부에 나타나는 난치성 질환인 백반증은 심리적인 위축감을 주어 정상적인 생활에 지장을 줄 수 있는 질병이다. 이에 따라서 본 연구에서는 피부에 나타나는 백반증의 진행 상태를 판단하기 위하여 L*a*b* 컬러 공간으로 변환된 피부 영상에 Otsu 임계값 설정 기법을 적용하여 백반증의 발병 영역을 자동으로 판별하는 알고리즘을 제안하였다.

• The Microorganisms and Industry
• /
• v.19 no.1
• /
• pp.33-36
• /
• 1993

세포성장 조절물질 탐색기술 개발 분야의 연구는 학문적으로는 세포성장 조절물질의 작용기작 규명에 의한 유전병의 병리기전, 암의 병리학적인 원인규명과 면역현상의 이해를 통한 생명과학의 기초연구 증진을 이룩할 것이며 세포성장 조절인자의 유전자를 분리하여 유전자 치료법(gene therapy)에 이용하거나 이들 유전자를 발현벡타를 이용해 과발현시켜 난치성 유전병의 치료에 이용하는 등의 임상실험에 활용할 수 있다. 산업적으로는 이들 연구결과를 활용한 신규 항암제 및 면역 조절제 개발기술의 수준 향상에 따른 생물 신의약 개발 분야에서 국제경재력을 제고시키는데 큰 역할을 할 것으로 기대된다.

• Proceedings of the Korean Society of Veterinary Pathology Conference
• /
• 2002.11a
• /
• pp.66-79
• /
• 2002

The basic treatments - Epithelial ＆ stromal debridement with a swab or diamond burr. - Possible placement of a collagen shield or nictitans flap. - Topical treatment with Adequan IM diluted in artificial tears : 1 ml Adequan + 4 ml tears : One drop four times daily. - Topical treatment with an antibiotic drop : Three times daily - 5％ sodium chloride ointment : Four times daily. If inflammation is severe - Topical treatment with nonsteroidal agent : Four times daily (Voltaren, Ocufen, or Profenyl) - Cyclosporine A (Optimmune) : Twice daily Healing time - Healing typically occurs rapidly - Fluorescein negative : 7-10 days - Vascular keratitis : Often several months

• Journal of the korean veterinary medical association
• /
• v.41 no.10
• /
• pp.918-928
• /
• 2005

체세포 핵이식을 통한 정상인과 환자 체세포 유래의 다능성 인간배아 줄기세포주 확립 및 응용 - 체세포 핵이식을 통한 다능성 인간 배아 줄기세포주 확립의 기술적 측면 - 인간배아줄기세포의 분화 : 발생생물학적 접근 및 세포치료에 대한 전망 - 마우스 배아줄기세포 기능들의 호르몬 조절 - 간엽줄기세포를 이용한 골조직 공학 - 조혈모세포의 재생 - 제대혈 유래 간엽줄기세포를 이용한 세포치료 - 난치성 혈액종양질환에서 수지상세포를 이용한 세포면역치료법 확립

• 보건세계
• /
• v.40 no.5 s.441
• /
• pp.6-11
• /
• 1993

초치료나 재치료를 막론하고 결핵환자치료의 대원칙은 첫째. 의사가 적절한 처방을 내리고 둘째. 환자가 적절한 처방을 정해진 기간동안 중단 없이 규칙적으로 복용하는 것이다. 의사와 환자가 각자의 원칙을 잘 지킨다면 초치료 때에도 치료에 실패하여 난치성 환자가 되는 경우가 많이 줄어들 것이다. 그러나 원칙은 간단하여도 그것을 실행한다는 것은 매우 어렵다. 더구나 초치료 때 보다도 재치료 때가 더욱 어렵다. 왜냐하면 의사의 입장에서는 초치료에 실패한 환자에게 적절한 재치료 처방을 하기가 꽤 까다롭고, 환자의 입장에서는 적절한 처방이라도 초치료처방 보다 치료기간이 더 길며 부작용 발생도 더 많은 재치료처방을 중단 없이 규칙적으로 복용하는 것이 상당히 어렵기 때문이다.

• Annals of Clinical Neurophysiology
• /
• v.9 no.2
• /
• pp.105-107
• /
• 2007

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.30 no.3
• /
• pp.250-257
• /
• 2017

Objectives : The purpose of this study is to know the effect of Korean medical treatments with Improvement of Intestinal Bacillus on prurigo nodularis. Methods : We treated a patient with prurigo nodularis with Korean Medicine and probiotic therapy. After treatment, we measured the change of nodule, itching and Intestinal Bacillus. Results & Conclusions : Symptoms of prurigo nodularis were improved remarkably. Nodule was reduced and itching was removed. Intestinal Bacillus were improved. Thus Korean medical treatments with Improvement of Intestinal Bacillus are effective on prurigo nodularis.

• Clinical and Experimental Pediatrics
• /
• v.49 no.9
• /
• pp.987-990
• /
• 2006

Intravenous immunoglobulin (IVIG) infusion is an effective therapy for acute Kawasaki disease (KD). Nonetheless, approximately 10 percent to 20 percent of patients have persistent or recrudescent fever despite IVIG treatment, leading to a higher risk for coronary artery aneurysms (CAA). This unresponsiveness may pose a challenge to the clinicians. Tumor necrosis $factor-{\alpha}$ levels are elevated in the acute phase of the disease, especially in patients who develop CAA. We report a 10-month-old male with KD who failed to respond to multiple doses of IVIG and methylprednisolone and who then was treated with infliximab (5 mg/kg single dose). After infliximab treatment, he became afebrile with normalization of inflammatory markers and no further progression of CAA.

• Korean Journal of Psychosomatic Medicine
• /
• v.5 no.2
• /
• pp.205-213
• /
• 1997

The aim of this study is to find the relationship between interictal psychiatric symptoms and seizure-related variables such as structural changes, regional interictal perfusion changes, the number of interictal epileptic discharges and the presence of accompanying generalized tonic clonic seizure(GTC). The subjects were 75 patients (47 males : mean age $28.3{\pm}7.7$) with intractable epilepsy, Interictal psychiatric symptoms were rated by Symptom Checklist-90-R(SCL-90-R). Each of 4 seizure variables was measured by MRI, $^{99m}TC-HMPAO$ SPECT and the prolonged EEG monitoring. The mean SCL-90-R subscale T-scores and the ratio of the patients with definite psychiatric symptoms(T-score > 65 at any one subscale of SCL-90-R) were compared among the groups with different seizure variables. Demographic variables and clinical variables were not statistically different among the groups with different seizure variables. The patients with right mesial temporal sclerosis had higher mean SCL-90-R scores for obsessive compulsive symptom, interpersonal sensitivity, depression, hostility and psychotic symptoms than the patients with left mesial temporal sclerosis, and they also showed higher ratio of definite psychiatric symptoms. The presence of interictal epileptic discharges was related with higher T-scores of paranoid subscale. The areas of hypoperfusion, the presence of the GTC, and other clinical seizure variables showed no significant influences on the mean SCL-90-R subscale T-scores. from these results, the authors speculated that interictal subictal epileptic dischrages may be related with psychiatric symptoms of the intractable epileptic patients, especially with right mesial temporal sclerosis.

• Journal of Chest Surgery
• /
• v.42 no.6
• /
• pp.785-788
• /
• 2009

Many patients with upper abdominal organ cancers, including pancreatic cancer, suffer from severe pain, and various methods and techniques have been used for relieving this pain. We present here two cases of patients with pancreatic cancer and they were both successfully relieved of their abdominal pain by performing video-assisted thoracoscopic sympathectomy and splanchnicectomy. This minimally invasive procedure offers promise in carefully selected patients with severe pain from pancreatic cancer and other conditions.