• 제목/요약/키워드: 김현옥

검색결과 99건 처리시간 0.028초

인간 골수 기질세포 이종이식이 백서의 축삭절단 안와하 신경 재생에 미치는 효과 (XENOTRANSPLANT OF HUMAN BONE MARROW STROMAL CELLS; EFFECT ON THE REGENERATION OF AXOTOMIZED INFRAORBITAL NERVE IN RATS)

  • 박은진;김은석;김진만;김현옥;염광원
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
    • /
    • 제31권3호
    • /
    • pp.239-247
    • /
    • 2005
  • This study demonstrated that xenogenic human marrow mesenchymal stem cells (hMSCs) could elicit the regeneration of the sensory nerve after axotomy in the adult rats infraorbital nerves without immunosuppression. For this, we evaluated the behavioral testing for functional recovery of the nerve and histological findings at weeks 3 and 5 compared to controls. Xenogenic hMSCs did not evoke any significant inflammatory or immunologic reaction after systemic and local administrations. HMSCs-treated rats exhibited significant improvement on sensory recovery tested with von Frey monofilaments. At 5 postoperative weeks, in the hMSCs treated nerve, expression of myelin basic protein (MBP), neurofilament (NF) at the site of axotomy was higher than control. And mRNA expression of neurotropin receptor Trk precursor (TrkPre), nerve growth factor receptor (NGFR) and neuropeptide (NPY) in trigeminal ganglion were also higher. The number of myelinated nerve at distal stump and cells in trigeminal ganglion were higher in hMSC treated rats. So it was supposed that transplanted MSCs contributed to reducing post-traumatic degeneration and production of neurotrophic factors. Immunofluorescence labeling showed small portion of hMSCs (<10%) expressed a phenotypic marker of Schwann cell (S-100). Xenogenic or allogenic mesenchymal stem cells might have immune privileged characteristics and useful tool for cell based nerve repair.

일 지역 초등학생의 성문제 행동 (The Sexual Problem Behavior of the Primary School Students in a Region)

  • 김현옥;박광숙;전미숙
    • Child Health Nursing Research
    • /
    • 제13권4호
    • /
    • pp.486-494
    • /
    • 2007
  • Purpose: This study was executed to investigate the route of the sexual knowledge acquisition and the sexual problem behavior of primary school students in a region. Method: The subjects of this research who were primary school 5, 6 grade students of 990 people were chosen at random in big cities, small towns and rural areas in Jeonbuk province. Result: The route of the sexual knowledge acquisition was through taking lesson & teacher in the school(40.6%), the peer group or senior member(26.1%), internet(15.3%), parents(10.0%), and multimedia(8.0%). The domain of the sexual problem behavior showed sexual impulse 3.8%, sexual violence 3.7%, masturbation 2.7%, voyeur 1.8%, prostitution 0.8%, transvestism 0.5%, exhibitionism 0.1%. The sexual problem behavior experienced by 5.0% or more of the subjects showed the experience of another person's compulsory touching on their body, the embrace desire and the kiss desire with opposite sexual friend. And the biggest sexual problem behavior of the subjects was sexual violence and sexual impulse to opposite sexual friend. The experience rate of the 6 grade was higher than that of the 5 grade (p<.05) and the male students' experience rate of another person's compulsory touching on their body showed higher than that of the female students(p<.05). Conclusion: The author through these findings suggests that systematic programs and curriculum should be developed for sexual problem behavior prevention.

  • PDF

감마나이프 수술 환자의 정위적 틀 고정을 위한 침윤 마취 시 통증 완화 중재의 효과 (The Effect of Pain Relieving Intervention During Infiltration among Gamma Knife Surgery Patients for Stereotactic Frame Fixation)

  • 장영준;김현옥
    • 대한간호학회지
    • /
    • 제48권2호
    • /
    • pp.221-231
    • /
    • 2018
  • Purpose: This study aimed to compare the effects of three interventions on pain, blood pressure, and pulse rate during infiltration anesthesia in patients about to undergo gamma knife surgeries. Methods: The three interventions employed in a university-affiliated Hospital in J City, South Korea were as follows: EMLA cream plus Vapocoolant spray (Vapocoolant, n=30), EMLA cream plus 10.0% Lidocaine spray (Lidocaine, n=30), and EMLA cream only (EMLA, n=30). The equivalent control-group pre test - post test study design was used. Pain was assessed subjectively using the numeric rating scale (NRS) and objectively using a Galvanic Skin Response (GSR) tester. NRS scores were assessed after infiltration anesthesia and the GSR was assessed during infiltration anesthesia. Blood pressure and pulse rate were assessed twice: before and after infiltration anesthesia. Data were collected between August 3, 2016 and March 24, 2017. Results: NRS scores after infiltration anesthesia and the GSR during infiltration anesthesia were significantly lower in the Vapocoolant group than in the Lidocaine and EMLA groups (F=13.56, p<.001 and F=14.43, p<.001, respectively). The increase in systolic blood pressure (F=4.77, p=.011) and in pulse rates (F=4.78, p=.011) before and after infiltration anesthesia were significantly smaller in the Vapocoolant group than in the Lidocaine and EMLA groups; however, no significant differences were observed in diastolic blood pressures (F=1.51, p=.227). Conclusion: EMLA cream plus Vapocoolant spray was the most effective intervention to relieve pain and to lower increase in systolic blood pressure and pulse rate caused by infiltration anesthesia for stereotactic frame fixation. Thus, application of Vapocoolant spray in addition to EMLA cream is highly recommended as a nursing intervention for patients undergoing gamma knife surgeries.

Geant4를 활용한 국제우주정거장 내의 조직등가비례계수기 모의 실험 (SIMULATION OF THE TISSUE EQUIVALENT PROPORTIONAL COUNTER IN THE INTERNATIONAL SPACE STATION WITH GEANT4)

  • 표정현;이재진;남욱원;김성환;김현옥;임창휘;박귀종;이대희;박영식;문명국
    • 천문학논총
    • /
    • 제27권3호
    • /
    • pp.81-86
    • /
    • 2012
  • The International Space Station (ISS) orbits the Earth within the inner radiation belt, where high-energy protons are produced by collisions of cosmic rays to the upper atmosphere. About 6 astronauts stay in the ISS for a long period, and it should be important to monitor and assess the radiation environment in the ISS. The tissue equivalent proportional counter (TEPC) is an instrument to measure the impact of radiation on the human tissue. KASI is developing a TEPC as a candidate payload of the ISS. Before the detailed design of the TEPC, we performed simulations to test whether our conceptual design of the TEPC will work propertly in the ISS and to predict its performance. The simulations estimated that the TEPC will measure the dose equivalent of about 1:1 mSv during a day in the ISS, which is consistent with previous measurements.

도시지역의 토지피복유형이 지표면온도에 미치는 영향: 경기도 일산 신도시를 중심으로 (Effect of the Urban Land Cover Types on the Surface Temperature: Case Study of Ilsan New City)

  • 김현옥;염종민
    • 대한원격탐사학회지
    • /
    • 제28권2호
    • /
    • pp.203-214
    • /
    • 2012
  • 콘크리트와 아스팔트가 상당 부분을 차지하는 도시의 물리적인 환경은 도시열섬효과를 일으키는 주요 원인이며, 일차적으로 토지이용 또는 토양피복에 따른 지표면온도의 상승으로 나타난다. 본 연구에서는 도시의 토지피복유형이 지표면온도에 미치는 영향을 공간해상도가 다른 MODIS, Landsat ETM+과 RapidEye 위성영상을 사용하여 비교 분석해 보았다. 연구대상지인 일산 신도시지역의 지표면온도는 토지 이용에 따라 뚜렷이 구분되는 패턴을 보여주었는데 건폐율이 높은 저층단독주택지구보다 건폐율이 낮고 녹지율이 높은 고층 아파트단지의 지표면온도가 현저히 낮게 나타났다. 토지피복유형과의 관계는 건물이나 도로 등 도시화지역의 면적이 증가할수록 기후존의 지표면온도가 증가하고, 식생과 수면, 그림자 지역의 면적이 늘어날수록 지표면온도는 떨어진다. NDVI와 지표면온도 사이에도 음의 선형상관관계가 나타나지만, 계절적 영향을 배제하기 어렵다는 단점이 있다.

지체 및 뇌병변 장애인의 보건 복지 서비스 요구도 조사 (A Study on the Needs of Health & Community Services Among the Disabled at Home in Rural Areas)

  • 김현옥;정경화
    • 지역사회간호학회지
    • /
    • 제18권3호
    • /
    • pp.480-491
    • /
    • 2007
  • Purpose: This study was to investigate the needs of health & community services among the disabled at home in rural areas. Methods: The subjects were 146 persons with disabilities living in J-gun. The questionnaire was based on the needs of 8 categorical services. Data were analyzed using frequency, percentage, mean, standard deviation, minimum, maximum, t-test, one-way ANOVA and Scheffe test. Results: Among the respondents, 27.4% visited the public health center in community for rehabilitation therapy. The average score of need was $2.62{\pm}.79$: education services $(2.92{\pm}1.05)$; medical services $(2.81{\pm}.82)$ nursing care services $(2.75{\pm}1.08)$; connection services $(2.62{\pm}1.20)$;, housing services $(2.60{\pm}1.09)$; emotional services $(2.41{\pm}1.03)$; other services $(2.24{\pm}1.06)$; and support of self-sustenance service $(1.92{\pm}1.15)$. The items in highest need were medical checkup (70.7%), medication (62.1%), traditional oriental therapy (60.4%) and physical therapy (58.9%), and those of lowest need were device repair (8.7%) and guidance of facility admission (7.1%). Needs were significantly different according to age (F=4.751. p=.001), employment status (t=2.108, p=.037) and medical fee payer (F=5.061, p=.002). Conclusion: The needs of education & medical services were relatively high. Demographic factors were statistically significant in determining needs. For the disabled at home in rural areas, more various services or programs should be executed based upon the needs and characteristics of based upon the needs and characteristics of the subjects.

  • PDF

초등학생의 비만과 관련된 지식, 태도, 행태에 관한 연구 (Knowledge, Attitude and Behavior Related to Obesity in Elementary School Children)

  • 이명하;김현옥;형희경;김희선
    • 지역사회간호학회지
    • /
    • 제18권3호
    • /
    • pp.469-479
    • /
    • 2007
  • Purpose: This study was carried out to investigate the knowledge of obesity and exercise , attitude to dietary habits and exercise, and physical activities and exercise in elementary school children to provide basic data for obese programs. Methods: The subjects were 850 elementary school children of grade 3-6 in C City and data were collected with a questionnaire. Results: Higher grade, female and overweight children recorded a higher knowledge score than lower grade, male and normal weight children. As for attitude to dietary habit, lower grade and female children had more positive attitude than higher grade and male children. Overweight children were more aware of the seriousness of exercise than normal weight children. In physical activity, lower grade and male children were higher than higher grade and female children. The more interested the children's family were in exercise, the higher score of physical activity they showed. Conclusion: In planning education for preventing obesity, it should give consideration to lower glade and male children. In addition, education for changing dietary habit attitude must be extended to higher grade and male children as well. It is effective to develop and apply physical activity improvement programs in the cooperation and involvement of their families.

  • PDF

전단교통사고에 의한 광범위 간장손상 - 보존치료 1례 (Extensive Blunt Hepatic Injury due to Cross-over Traffic Accident - A Case Report of Conservative Management)

  • 장인석;김성환;이정은;김종우;최준영;신일우;김현옥
    • Journal of Trauma and Injury
    • /
    • 제27권3호
    • /
    • pp.84-88
    • /
    • 2014
  • The severity of blunt hepatic injury correlates with internal organ damage. We experienced a patient, who had an extensive crushed liver injury. The patient was a 28-year-old man, who was involved in a traffic accident in which a wheel ran over his right upper abdomen. A grade V severe hepatic laceration was diagnosed with computed tomography. His vital signs were stable, so we could wait for times with conservative management. Bile leakage led to biloma and bile spillage into the peritoneal space. Selective percutaneous drainage was needed to control the several biloma. After four months of conservative management, could the patient was discharged in good condition.

대한수혈학회 창립 30주년을 기념하며 (History of the Korean Society of Blood Transfusion and Blood Services in Korea)

  • 조한익;서동희;김현옥
    • 대한수혈학회지
    • /
    • 제23권2호
    • /
    • pp.97-106
    • /
    • 2012
  • The Korean Society of Blood Transfusion (KSBT) was established in Seoul in 1982 by a group of physicians of clinical pathology (currently laboratory medicine), internal medicine, paediatrics, anaesthesiology, and surgery, who were members of the Korean Society of Hematology, in which they had been actively engaged as transfusion specialists. However, these physicians were dissatisfied with the lack of public recognition of blood transfusion and the unrealistic blood service system and therefore attempted to build an influential organization for improvement of blood services and transfusion medicine. The mission of the KSBT is to advance the science and practice of transfusion medicine. The KSBT advocates for education and research in the fields of transfusion medicine and for safe blood in blood services. The inaugural KSBT conference, with approximately 50 participants, was held in November, 1982; since then, annual conferences and educational workshops have been held regularly once or twice a year. Currently, the KSBT has approximately 800 members, who are practitioners of blood transfusion (holders of M.D.) or staff members of blood services (holders of other professional degrees). The Society also publishes the Korean Journal of Blood Transfusion (first issue published in 1990) and guidelines for blood services. A Society web site (http://www.transfusion.or.kr) was started in 2001, with the hope of increasingly providing information and feedback to members on a real-time basis. The KSBT has been an active participant in international activities. In 1995, the KSBT hosted the Sixth ISBT Western Pacific Regional Congress in Seoul and will host the $33^{rd}$ ISBT Congress in Seoul in 2014. Since its inauguration, the KSBT has had key roles not only in education and research in the fields of transfusion medicine but also in development of safe-blood services during the last 30 years.

간호대학생의 학업적 자기효능감이 학업성취도에 미치는 영향: 전공만족도의 매개효과 (Academic Achievement of Nursing College Students according to Academic Self-efficacy: The Mediating Effect of Major Satisfaction)

  • 김주연;김현옥;이명하
    • Child Health Nursing Research
    • /
    • 제25권2호
    • /
    • pp.205-213
    • /
    • 2019
  • Purpose: The purpose of this study was to examine the mediating effect of major satisfaction in the relationship between academic self-efficacy and academic achievement among nursing students. Methods: Data were collected from 142 nursing students from March 5 to March 9, 2018, and the collected data were analyzed using SPSS version 21.0 for Windows. Results: Academic self-efficacy had a significant effect on both major satisfaction (${\beta}=.31$, p<.001), and academic achievement (${\beta}=.43$, p<.001). The parameter of major satisfaction was found to have a significant effect on the dependent variable, academic achievement (${\beta}=.22$, p=.007), and the independent variable, academic self-efficacy, also had a significant effect on academic achievement (${\beta}=.39$, p<.001). Thus, major satisfaction was found to have a partial mediating effect on the relationship between academic self efficacy and academic achievement. The Sobel test showed that the path of the academic achievement and academic self efficacy variables was significantly mediated by major satisfaction (Z=2.99, p=.003). Conclusion: Academic self-efficacy was found to affect academic achievement, and major satisfaction was found to play a partial mediating role in the relationship between academic self efficacy and academic achievement.