• The Korea Journal of Herbology
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• v.27 no.6
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• pp.115-122
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• 2012

Objectives : This study evaluated activities and ingredient contents concerning extracts according to extraction solvents of Insampaedok-san (IS, Renshen bai du-san). Methods : The herbal constituents of IS were extracted with water and 70% ethanol at $100^{\circ}C$ for 2 hr. Using the HPLC system, the six ingredient contents of different solvent extracts of IS were analyzed. The nitric oxide (NO), prostaglandin $E_2$ ($PGE_2$) production and proinflammatory cytokines were measured in RAW264.7 cells stimulated with lipopolysaccharide (LPS). The macrophage-derived chemokine (MDC/CCL22) and regulated on activation normal T-cell expression and secreted (RANTES/CCL5) production were measured in HaCaT and BEAS-2B cells stimulated tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$) and interferon-${\gamma}$ (IFN-${\gamma}$). The activities of glycerol-3-phosphate dehydrogenase (GPDH) and leptin level were measured in 3T3-L1 cells. Results : The calibration curves showed good linearity ($r^2$=1.0000) for different concentration ranges. The contents of liquiritin, naringin, hesperidin, neohesperirin and glycyrrizin in 70% ethanol extracts of IS were relatively higher than that of water extract, however the content of ferulic acid in 70% ethanol and water extract of IS were similar. The extraction solvents of water and 70% ethanol were evaluated inhibitory effect on the production of NO, $PGE_2$, TNF-${\alpha}$ and IL-6 in RAW 264.7 cells. Their extractions were inhibitory effect on production of MDC/CCL22 and RANTES/CCL5 in HaCaT cell and BEAS-2B cell, respectively. In addition, evaluated reduced on GPDH activity and leptin level in 3T3-L1 preadipocyte cell. Conclusions : Our results suggest that IS extracts were inhibitory effects of disease such as inflammation, allergies and obesity.

• Resources Recycling
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• v.17 no.6
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• pp.50-56
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• 2008

A polypropylene fraction collected from the stream of post-consumer plastics was pyrolyzed. The aim of this study is to observe the dependence of yield of BTEX-aromatics normally used as solvent on the reaction temperature. To reach the goal, three experiments were carried out at different temperature between 650 and $700^{\circ}C$, using a fluidized bed reactor that shows an excellent heat transfer. In the experiments, product gases were used as a fluidizing medium to maximize the amount of BTEX-aromatics at fixed flow rate and feed rate during the pyrolysis. Oil, gas and char were obtained as product fractions. Product gases were analyzed with GCs(TCD, FID) and with a GC-MS system for qualitative analysis. For an accurate analysis of product oil, the product oil was distilled under vacuum, and separated the distillation residues from oil fractions that were actually analyzed with a GC-MS system. As the reaction temperature went higher, the content of BTEX-aromatics increased. The maximal yield of BTEX-aromatics was obtained at $695^{\circ}C$ with a value of about 30%. The main compounds of product gas were $CH_4$, $C_2H_4$, $C_2H_6$, $C_3H_6$, $C_4H_{10}$ and the product gas had an higher heating value about 45MJ/kg. It could be used as a heat source for a pyrolysis plant or for other fuel applications.

• Journal of agricultural medicine and community health
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• v.33 no.3
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• pp.316-323
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• 2008

= ABSTRACT = Objectives : Incheon metropolitan city has set a model program of community partnership for hypertensive or diabetic patients detection and follow-up since 2005. This study examines the effects of the model on the compliance and the control of blood pressure or blood sugar level Methods : Telephone-surveys were done for 140 persons selected from 408 patients who were detected newly as hypertensive or diabetic patients at Gangwha-Gun and Seo-Gu in Incheon between January 1st and August 31th in 2006, and finally completed in 110 patients(78.6%). Survey questionnaires included socio-demographic(age, gender, and educational level), health behavioral (smoking, drinking, physical activity, and diet), and therapy-related (registration state, compliance, blood pressure or blood sugar control) variables. Odds ratio and 95% CI were derived from logistic regression model. Results : Registered group exhibited high compliance and well managed blood pressure or blood sugar level. The odds ratio of registration were 5.55(95% CI:1.83~16.89) for compliance and 3.78(95% CI:1.43~9.99) for blood pressure or blood sugar control after adjusting for age, gender, disease, and area Conclusions : It is independently related to compliance and blood pressure or blood sugar control whether the patient is registered or not. To control hypertension or diabetes mellitus in terms of compliance and control state, a community-based registration program through community partnership could be a powerful tool.

• Journal of Soil and Groundwater Environment
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• v.13 no.2
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• pp.62-69
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• 2008

In this study physicochemical characteristics and stability of various manganese coated sands (MCS) prepared with different methods were evaluated. In addition, removal efficiencies of As(III) by each MCS were compared. Four different MCSs were used; B-MCS prepared by baking method, W&D-MCS prepared by wetting and dry method, NMCS prepared during the water treatment process and Birm which is a commercial MCS widely used for the removal iron and manganese. The manganese content in each MCS was following order: Birm (63,120 mg/kg) > N-MCS (10,400 mg/kg) >W&D-MCS (5,080 mg/kg) > B-MCS (2,220 mg/kg). Birm showed the least solubility (% basis) in acidic conditions. As(III) oxidation efficiency of B-MCS was continuously increased as the solution pH decreased. While As(III) oxidation efficiency of N-MCS and Birm was minimum around neutral pH. The increased As(III) oxidation efficiency above neutral pH for N-MCS and Birm could be due to the competitive adsorption of $Mn^{2+}$, which was produced from reduction of $MnO_2$, onto the surface of aluminum and manganese oxides.

• Journal of the Korean Geotechnical Society
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• v.28 no.3
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• pp.15-23
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• 2012

An internal friction angle, which is one of strength parameters of granular soils, can be obtained from direct shear tests or triaxial tests. The result of traixial tests can be influenced by various experimental conditions such as confining pressure, shearing rate, specimen diameter and height, and end constraint. In this study, undrained and drained shearing behaviors of Nakdong River sand were investigated for loose (Dr = 40%) and dense (Dr = 80%) specimens with 5, 7, and 10 cm in diameter. Friction angles such as undrained total stress friction angle, undrained effective stress friction angle, and drained friction angle obtained from Mohr's stress circle slightly increased and then decreased as a diameter of a specimen increased from 5, 7 to 10 cm, regardless of relative densities. The difference between friction angles caused by different specimen size was at maximum 4.5 degrees for undrained total stress friction angle of dense specimen. In most cases, there was little difference between friction angles of large and small specimens, which was less than 2 degrees. The difference between an effective friction angle from undrained tests and a drained friction angle from drained tests was at maximum 7 degrees for loose samples but negligible for dense samples.

• Korean Journal of Environment and Ecology
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• v.26 no.3
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• pp.374-381
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• 2012

In this study, ecological characteristics of Zacco platypus population in Lake Hoengseong region, including the up-and downstream in Lake, were investigated from April to November, 2010. The results compared with regional dynamics of Z. platypus population showed a dominant population among the other fish population, and also upstream has relatively high as 1,707 (78.70%) individuals than those of other sites. The regression coefficient (b) in relation to length-weight on Z. platypus population were 3.28 which appeared relatively a stabilized habitat condition in Lake Hoengseong region and 3.28 at the upstream and 3.10 in Lake Hoengseong and 3.09 at the downstream. Condition factor on Z. platypus population in Lake Hoengseong region showed stabilized population as 0.003 value, and especially the condition factors at the upstream were relatively higher than those at the downstream and Lake Hoengseong, indicate that Z. platypus population at the upstream displayed to be maintained as the most good condition in relation to trophic states. As a results of compared with body size on Z. platypus population, was investgated as highly distribute between 30~50mm and 70~90mm at upstream; 60~80mm in Lake Heongseong; 70~100mm at downstream, respectively. As a results, Z. platypus population at the upstream among Lake Hoengseong region displayed the most stabilized growth condition, and Z. platypus population were inhabitable in lotic and lentic environments based on good habitat condition.

• Korean Journal of Ichthyology
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• v.24 no.3
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• pp.160-166
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• 2012

Egg development and early life history of the endangered Korean freshwater fish, Microphysogobio koreensis, was investigated to get a basic information for establishing its conservation strategy. The matured adult fishes were sampled at Imsil-gun, Jeollabuk-do, Korea in May 1 2012 and artificially fertilized. The fertilized eggs were spherical, separated demersal and $1.8{\pm}0.14mm$ in diameter. The hatching of the embryo began at about 29 hours after fertilization under water temperature of $23^{\circ}C$. The newly hatched pre-larvae were average $2.2{\pm}0.48mm$ in total length. At 4 days after hatching, the post-larvae were $3.6{\pm}0.55mm$ in total length and york sac was completely absorbed. At 20 days after hatching, their fin rays were formed and finally the larvae entered juvenile stage and grew up to $6.5{\pm}0.77mm$ in total length. At 60 days after hatching, the total length reached $24.4{\pm}1.71mm$, and the band patterns of he head and lateral side were similar to adult fish. Based on this study, the fertilized eggs of M. koreensis hatched more quickly and the pre-larvae length was also smaller, compared with related species.

• Tuberculosis and Respiratory Diseases
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• v.44 no.1
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• pp.183-190
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• 1997

Tocolytics are agents widely used in the treatment of premature labor to inhibit uterine contractions. Ritodrine is most commonly used tocolytic agent and acts by increasing intracellular cyclic adenosine monophosphate, which decreases the activity of myosin light-chain kinase, the rate-limiting enzyme in the signal network leading to contraction. Physiologic effects associated with the use of ritodrine are due to their effect on bera-l as well as beta-2 receptors. Some of maternal complications of therapy are rachycardia, hyperglycemia, hypokalemia, lactic acidosis, myocardial ischemia, and pulmonary edema. Tocolytics induced pulmonary edema is a serious complication that can lead to marternal death, although infrequent, The incidence varies from 0.5% to 5% of those receiving these agents. Predisposing factors include the concommitant use of corticosteroid, twin gestation, fluid overload (particularly with saline), and anemia. Several mechanisms have been postulated, but the pathogenesis is uncertain. It is suggested that both types of mechanism, hydrostatic and permeability induced, might be involved. The association of tocolytic therapy with pulmonary edema appears to be unique to the pregnant state, because this complication has never been reported in asthmatic patients exposed to high dosages. We report a case of tocolytic induced pulmonary edema developed in 24 hours after delivery.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.28 no.1
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• pp.1-8
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• 2015

In this paper, computational evaluation method for fatigue crack growth rate(FCGR) based on material viscoplastic-damage model is proposed. Viscoplastic-damage model expressing material constitutive behavior of 7% nickel steel is introduced and is implemented into commercial finite element analysis(FEA) code, ABAQUS, as a user defined material subroutine(UMAT) for application in the FEA environments. Verification of developed UMAT and material parameters of material model are carried out by uniaxial tensile test simulations of 7% nickel steel. Moreover, jump-in-cycles procedure and rearrangement of critical damage are employed and also implemented to the ABAQUS UMAT for fatigue damage analysis. Typical FCGR test results such as relationship between crack length and number of cycles and relationship between da/dN and ${\Delta}K$ could be obtained from FCGR test simulation using developed UMAT and these results are compared with experimental results in order to verify of proposed computational method.

• Journal of the Korean Geosynthetics Society
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• v.12 no.4
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• pp.11-19
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• 2013

Recently despite the development of analysis program and construction technologies, collapse at the many earth retaining wall construction site of the structure due to the economic and human damage has occurred. The results of geothechnical investigation studies field, it was found to differ from the results of the original design. There may be errors parameters calculated from the results of ground investigation in such a case. And it can be estimated that it is irrational to behavior analysis of the earth retaining wall were analyzed by utilizing the parameters. And in this study, parameters that affect the earth retaining wall the correlations were analyzed using elasto-plastic method. Analysis method was changed various parameters (cohesion, subgrade reaction coefficient, load condition) applied to the elasto-plastic method. And due to a change in the behavior of earth retaining wall materials were analyzed. As a result, the cohesion greatly affects the behavior of earth retaining wall materials in various parameters. For this reason, the results of the geothechnical investigation, confirmation of the actual ground is very important in the design of the earth retaining wall. And, calculating accurate and reasonable of the cohesion of the various parameters is very important.