• Title/Summary/Keyword: 기초의학

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Effects of the Modified Fasting Therapy Using Gamrosu and Herbal Medicine on Changes of Body Compositions in Women: Case Series (한약을 결합한 감로수 절식요법이 여성의 체성분 변화에 미치는 영향: 증례보고)

  • Baek, Seon-Eun;Park, Eun-Ji;Kim, Hae-Won;Yoo, Jeong-Eun
    • Journal of Korean Medicine for Obesity Research
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    • v.18 no.2
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    • pp.152-158
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    • 2018
  • The purpose of this study was to investigate the effects of modified fasting therapy using Gamrosu and herbal medicine on the changes of body compositions in women. We analyzed the medical records of 11 patients, who carried out modified fasting therapy at Dunsan Korean Medicine Hospital of Daejeon University. Body compositions (body weight, body mass index, body fat mass, skeletal muscle mass, basal metabolic rate, extracellular water ratio, abdominal circumference, thickness of abdominal subcutaneous fat, visceral fat area) were reviewed before and after modified fasting therapy. The body composition values (body weight, body mass index, body fat mass, skeletal muscle mass, basal metabolic rate, extracellular water ratio, abdominal circumference, thickness of abdominal subcutaneous fat, visceral fat area) decreased after modified fasting therapy. Results from this investigation showed that modified fasting therapy using Gamrosu and herbal medicine has positive effects on changes of body compositions.

Effect of Seomaeyakssuk (Artemisia argyi H.) Extracts on Anti-pruritic Activities (항가려움증 활성에 섬애약쑥(Artemisia argyi H.) 추출물이 미치는 영향)

  • Lee, Hea-Jin;Lim, Hyun-Ji;Lim, Mi-Hye
    • Journal of the Korean Applied Science and Technology
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    • v.38 no.5
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    • pp.1292-1301
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    • 2021
  • The purpose of this study was to investigate the anti-pruritic activities such as cell viability and pruritus-related factor using seomaeyakssuk (Artemisia argyi H.; Seomaeyakssuk) extract on MC/9 (mouse mast cell line). Seomaeyakssuk was extracted from hot distilled water. Cell viability was assessed using MTT assay on MC/9 cells. Anti-pruritic activities were measured through changes in the levels of transcription factor (IL4 and IL31) on MC/9 cells. In addition, the expression of linked proteins and histamine was measured. The results confirmed that significant cytotoxicity does not appear in the concentration range of 25, 50, and 100 ㎍/㎖. The levels of IL4 was reduced to 12% (25 ㎍/㎖), 26% (50 ㎍/㎖) and 61% (100 ㎍/㎖). Also, level of IL31 was decreased 33% (50 ㎍/㎖) and 36% (100 ㎍/㎖). In the case of proteins levels decreased significantly IL-4 34%/69% and IL-31 36%/37% at 50 ㎍/㎖ and 100 ㎍/㎖. Histamine decreased by 22, 58% and 61%, respectively, at concentrations of 25, 50, and 100 ㎍/㎖. This results shows possibility of ADD as raw material in anti-pruritic products.

Molecular epidemiologic trends of norovirus and rotavirus infection and relation with climate factors: Cheonan, Korea, 2010-2019 (노로바이러스 및 로타바이러스 감염의 역학 및 기후요인과의 관계: 천안시, 2010-2019)

  • Oh, Eun Ju;Kim, Jang Mook;Kim, Jae Kyung
    • Journal of Digital Convergence
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    • v.18 no.12
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    • pp.425-434
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    • 2020
  • Background: Viral infection outbreaks are emerging public health concerns. They often exhibit seasonal patterns that could be predicted by the application of big data and bioinformatic analyses. Purpose: The purpose of this study was to identify trends in diarrhea-causing viruses such as rotavirus (Gr.A), norovirus G-I, and norovirus G-II in Cheonan, Korea. The identified related factors of diarrhea-causing viruses may be used to predict their trend and prevent their infections. Method: A retrospective analysis of 4,009 fecal samples from June 2010 to December 2019 was carried out at Dankook University Hospital in Cheonan. Reverse transcription-PCR (RT-PCR) was employed to identify virus strains. Information about seasonal patterns of infection was extracted and compared with local weather data. Results: Out of the 4,009 fecal samples tested using multiplex RT-PCR (mRT-PCR), 985 were positive for infection with Gr.A, G-I, and G-II. Out of these 985 cases, 95.3% (n = 939) were under 10 years of age. Gr.A, G-I, and G-II showed high infection rates in patients under 10 years of age. Student's t-test showed a significant correlation between the detection rate of Gr.A and the relative humidity. The detection rate of G-II significantly correlated with wind-chill temperature. Conclusion: Climate factors differentially modulate rotavirus and norovirus infection patterns. These observations provide novel insights into the seasonal impact on the pathogenesis of Gr.A, G-I, and G-II.

Comparison of CT Image Performance with or without Tin Filter based on Blind Image Quality Evaluation Method (블라인드 품질 평가 방법을 사용한 주석필터 사용 유무에 따른 CT 영상 특성 비교)

  • Shim, Jina;Lee, Youngjin
    • Journal of the Korean Society of Radiology
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    • v.15 no.3
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    • pp.301-306
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    • 2021
  • The use of tin filters as a way to reduce the medical radiation in computed tomography (CT). However, due to the changed X-ray spectrum with the use of tin filters, disease diagnosis could be affected because it appears as images of different impressions from previous images. Therefore, this study evaluates the changes in images when using tin filter and high pitch in chest low-dose CT. In this study, images were acquired in groups of three for comparison. Group 1 did not apply to tin filter, and used the existing pitch 0.8. Group 2 used a tin filter, pitch 0.8, Group 3 used a tin filter, and pitch 2.5. To compare the image quality, the natural image quality evaluator (NIQE) and the blind/referenceless image quality evaluator (BRISQUE) were used among the blind quality evaluation factors depended on a no-reference basis. As a result, the NIQE values were low in the order of Group 1, Group 3, and Group 2. BRISQUE values were low in the order of Group 3, Group 2 and Group 1. This study confirms the superiority of images of tin filter and high pitch techniques in chest low-dose CT, which is considered to be a fundamental study for acquiring accurate images of patients with difficult breathing control.

Development and Validation of the Parental Role Responsibilities Scale (부모의 양육 역할 책임 척도 개발 및 타당화 연구)

  • Hwang, Ock-Kyeung;Jung, Youn-Ah;Song, Mi-Ryoung;Myung, Jun-Hee
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.2
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    • pp.440-451
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    • 2021
  • The purpose of this study is to develop and validate the parental roles and responsibilities for young children. A survey was conducted on 301 parents with children attending preschools. The parental roles and responsibilities scale were determined from a total of 60 items and 11 sub-factors based on the criteria for goodness, validity, and reliability of items (i.e., factor load ≥ 0.5; AVE ≥ 0.5; CR ≥ 0.7; Cronbach's alpha ≥ 0.7). The parental roles and responsibilities scale include 'hygiene management' (4 items), 'physical activities' (6 items), 'survival and health care' (6 items), 'cognitive development' (5 items), 'emotional stability' (5 items), 'social skills' (6 items), 'social norms and values' (7 items), 'physical environment' (5 items), 'protection' (5 items), 'family community consciousness and family tradition' (4 items), and 'the role and responsibility of parents for childcare institutions' (7 items). It is significant that the indicators on the parental roles and responsibilities for young children were developed and verified to fit the situation in Korea. Findings will help identify the characteristics of parental role responsibilities and serve as a basis for efficient communication between parents and preschoolers.parental role responsibilities and serve as a basis for efficient communication between parents and preschools.

A Convergence Study of the Research Trends on Stress Urinary Incontinence using Word Embedding (워드임베딩을 활용한 복압성 요실금 관련 연구 동향에 관한 융합 연구)

  • Kim, Jun-Hee;Ahn, Sun-Hee;Gwak, Gyeong-Tae;Weon, Young-Soo;Yoo, Hwa-Ik
    • Journal of the Korea Convergence Society
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    • v.12 no.8
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    • pp.1-11
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    • 2021
  • The purpose of this study was to analyze the trends and characteristics of 'stress urinary incontinence' research through word frequency analysis, and their relationships were modeled using word embedding. Abstract data of 9,868 papers containing abstracts in PubMed's MEDLINE were extracted using a Python program. Then, through frequency analysis, 10 keywords were selected according to the high frequency. The similarity of words related to keywords was analyzed by Word2Vec machine learning algorithm. The locations and distances of words were visualized using the t-SNE technique, and the groups were classified and analyzed. The number of studies related to stress urinary incontinence has increased rapidly since the 1980s. The keywords used most frequently in the abstract of the paper were 'woman', 'urethra', and 'surgery'. Through Word2Vec modeling, words such as 'female', 'urge', and 'symptom' were among the words that showed the highest relevance to the keywords in the study on stress urinary incontinence. In addition, through the t-SNE technique, keywords and related words could be classified into three groups focusing on symptoms, anatomical characteristics, and surgical interventions of stress urinary incontinence. This study is the first to examine trends in stress urinary incontinence-related studies using the keyword frequency analysis and word embedding of the abstract. The results of this study can be used as a basis for future researchers to select the subject and direction of the research field related to stress urinary incontinence.

Quality Evaluation of the Occupational Therapy Guidelines for Stroke (뇌졸중 작업치료 지침의 질 평가)

  • Lee, Eun-Young;Han, Dae-Sung;Park, Ji-Hyuk
    • Therapeutic Science for Rehabilitation
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    • v.10 no.3
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    • pp.57-69
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    • 2021
  • Objective : The purpose of this study was to identify occupational therapy guidelines for patients with stroke according to the clinical guidelines, and to investigate the quality and characteristics of the identified guidelines. Methods : This involved a review of domestic and foreign rehabilitation treatment guidelines from 2008 to 2019. These guidelines were searched using, the search terms: 'stroke', 'guideline', 'practice guideline', 'recommendation', 'protocol compliance', 'practice guideline', and 'stroke guidelines'. Results : A total of 708 papers were identified from the search. Eight guidelines met the selection criteria and were included in this review. The selected guidelines were developed in Canada, Australia, the United States, the United Kingdom, and Korea. One of the eight guidelines was occupational therapy guidelines, and the other seven were rehabilitation guidelines. The guidelines were categorized into a total of 36 topics, including 28 guidelines for stroke rehabilitation in Australia, 24 guidelines for the British and American Heart Association, and 23 guidelines for stroke rehabilitation developed in Korea. Conclusion : In this study, the guidelines for occupational therapy for existing stroke patients were identified, and the quality and characteristics of the guidelines were compared. The results of this study will provide important basic data for the development of occupational therapy guidelines for stroke in the future.

Image Evaluation Analysis of CT Examination for Pedicle Screw Insertion (척추경 나사못 삽입술 CT검사의 영상평가 분석)

  • Hwang, Hyung-Suk;Im, In-Chul
    • Journal of the Korean Society of Radiology
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    • v.16 no.2
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    • pp.131-139
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    • 2022
  • The purpose of this study was to insert a pedicle screw into a pig thoracic vertebrae, a general CT scan(Non MAR), and a thoracic axial image obtained with the Metallic Artifact Reduction for Orthopedic Implants (O-MAR) to reduce artifacts. The image obtained by reconstructing the algorithm (Standard, Soft, Bone, Detail) was used using the image J program. Signal to noise ratio(SNR) and contrast to noise ratio(CNR) were compared and analyzed by obtaining measured values based on the given equation. And this study was to investigate tube voltage and algorithm suitable for CT scan for thoracic pedicle screw insertion. As a result, when non-MAR was used, the soft algorithm showed the highest SNR and CNR at 80, 100, 120, and 140 kVp, On the other hand, when MAR was used, the standard algorithm showed the highest at 80 kVp, and the standard and soft algorithms showed similar values at 100 kVp. At 120 kVp, the Soft and Standard algorithms showed similar values, and at 140 kVp, the Soft algorithm showed the highest SNR and CNR. Therefore, when comparing Non-MAR and MAR, even if MAR was used, SNR and CNR did not increase in all algorithms according to the change in tube voltage. In conclusion, it is judged that it is advantageous to use the Soft algorithm at 80, 100, 120, and 140 kVp in Non MAR, the Standard algorithm at 80 and 100 kVp in MAR, and the Soft algorithm at 120 and 140 kVp. This study is expected to serve as an opportunity to further improve the quality of images by using selective tube voltage and algorithms as basic data to help evaluate images of pedicle screw CT scans in the future.

Evaluation of 3D Printing Filaments for Radiation Shielding using High Density Polyethylene and Bismuth (고밀도 폴리에틸렌과 비스무트를 이용한 3D 프린팅용 방사선 복합필라멘트 개발 및 차폐능력 평가)

  • Park, Ki-Seok;Kim, Dong-Hyun
    • Journal of the Korean Society of Radiology
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    • v.16 no.3
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    • pp.233-240
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    • 2022
  • Research on the presence or absence of radiation shielding for FDM-type filaments has recently begun to be studied, but filaments with shielding capabilities are not sold in Korea, and not studies yet. Therefore, in this research, we will use HDPE (High Density Polyethylene) as a base material, select bismuth as a reinforcing material to manufacture a composite filament, evaluate the shielding ability, and provide basic data for the development of a radiation shielding composite material using 3D printing.A filament is produced by mixing Bismuth with an effective atomic number 83 with HDPE of PE series and adjusting the content of Bismuth to 20% wt, 30% wt, 40% wt. Compounded filaments were evaluated for their physical properties and shielding capabilities by ASTM evaluation methods. As the bismuth content increases, the density, weight, and tensile strength increase, and the shielding capacity is confirmed to be excellent. As a result of the radiation shielding capacity evaluation, it was confirmed that HDPE (80%) + Bi (20%) showed a shielding rate of 82% at 60 kV and a shielding rate of up to 94% or more at 40% bismuth content. In this study, we confirmed that it was possible to produce a radiation shield that is lighter than the metal particle-containing filaments. Furthermore, that have been shield radiation by using HDPE + Bi filaments, and radiation in the medical and radiation industries. The possibility of using it as a shielding complex was confirmed.

A Study on the Modern Implication and Religious Value of Medicine Buddha Faith (약사여래 신앙의 현대적 의미와 신앙적 가치 고찰)

  • Kim, Jung-Suk
    • The Journal of the Korea Contents Association
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    • v.22 no.6
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    • pp.428-438
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    • 2022
  • The purpose of this study was to examine the modern implication and religious value of the Medicine Buddha faith. Accordingly, the theoretical background of Medicine Buddha faith was reviewed based on various literature, including Bhaisajyaguru Sutra, a representative literature on Medicine Buddha, and the two key goals of Medicine Buddha faith were set up and analyzed. As a result of this study, the modern implication and religious value of the Medicine Buddha faith were presented as follows. First of all, it is the modern implication of the Medicine Buddha faith. First, the Medicine Buddha faith promotes a shift in the perspective that disease is the subject of healing, not treatment. Second, the Medicine Buddha faith expands diseases not only to medical diseases but also to disabilities and makes them an object of healing. Third, the Medicine Buddha faith promotes healing through performance that strengthens the positivity of the mind. Next is the religious value of the Medicine Buddha faith. First of all, the Medicine Buddha faith has strong religious acceptance. Second, the Medicine Buddha faith is characterized by being accepted by modern people beyond religion and sect. Based on the results of this study, this study made suggestions to improve the quality of life of modern people suffering from pain in their daily lives due to diseases and unnatural death.