• Title/Summary/Keyword: 기초대사

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Influencing Factors of the Metabolic Index and Cardiovascular Risk Factors on Depressive and Non-depressive Groups in the Vulnerable Diabetic Elderly Women (취약계층 당뇨병 여성노인의 대사증후군지표와 심혈관 위험정도가 우울증상 여부에 미치는 요인)

  • Sung, Kiwol
    • Journal of Korean Biological Nursing Science
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    • v.21 no.2
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    • pp.123-132
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    • 2019
  • Purpose: The purpose of this study was to identify influencing factors of metabolic index and cardiovascular risk factors, on depressive and non-depressive groups, in vulnerable diabetic elderly women. Methods: Participants were 137 vulnerable diabetic elderly women, using health centers in D city. Data were collected through interviews September though December 2017. The metabolic index was measured using National Cholesterol Education Program-Adult Treatment Panel III (NCEP-ATP III), and cardiovascular risk factors were measured using Framingham Risk Score (FRS). Depressive and non-depressive groups were divided by the score of Geriartric Depress Scale Short Korea Version (GDSSF). Collected data were analyzed using a x2 test, independent t-test, and binary logistic regression, with the SPSS/WIN 25.0 program. Results: Vulnerable diabetic elderly women, did not exercise in the depressive groups, and had higher triglyceride (TG), total cholesterol (TC) and larger waists, than in the non-depressive group. Results show that lack of exercise (OR= 6.30), is the highest risk factor, influencing the depressive symptom in vulnerable diabetic elderly women. Conclusion: These results suggest that to reduce depressive symptom levels among vulnerable diabetic elderly women, nursing interventions are needed to increase exercise and decrease TG, TC, and waist size, particularly in improving exercise of vulnerable diabetic elderly women.

Identification of Key Metabolites Involved in Quantitative Growth of Pinus koraiensis (잣나무의 생장특성과 관련있는 주요 대사물질 인자 구명)

  • Lee, Wi Young;Park, Eung-Jun;Han, Sang Urk
    • Journal of Korean Society of Forest Science
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    • v.101 no.4
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    • pp.640-647
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    • 2012
  • A metabolomic study was conducted to identify key metabolic components, which are correlated with the growth of 4-year-old Pinus koraiensis seedlings harvested at actively height growing season (May 18th). Among 105 individual metabolites identified by GC/MS analysis, alanine, threonine, oleic acid, and butanoic acids were negatively correlated with both height and weight of 4-year-old seedlings, while malic acid, xylose, glucose, d-turanose and inositol had positive correlation with various growth parameters. During the actively growing season, the concentrations of both amino acids and organic acids in the main stem of Superior seedling group were lower but the photosynthates such as mono-saccharide and sucrose were higher than in other seedling groups such as Intermediate and Inferior. Interestingly, d-turanose, an analogue of sucrose that is not metabolized in higher plants but used as carbon source by many organisms including numerous species of bacteria and fungi, showed the highest correlation (r=0.896, p<0.001) with height of 4-year-old seedlings, indicating that possible interaction with mycorrhizal organisms. Therefore we suggest that several metabolites selected in this study may be used as metabolic markers for complex traits in P. koraiensis.

The Effect of 12weeks Pilates Mat Exercise on Body Composition and Lipid Metabolism in Obese Middle-aged Women (12주간 필라테스 매트 운동이 비만중년여성의 신체구성 및 지질대사에 미치는 영향)

  • Baek, Soon-Gi
    • Journal of Industrial Convergence
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    • v.18 no.5
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    • pp.108-117
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    • 2020
  • This study aims to provide basic data for maintaining and promoting health of obese middle-aged women who are interested in various chronic diseases such as cardiovascular disease and coronary artery disease by comparing and analyzing the effect on body composition and lipid metabolism through a 12-week Pilates mat exercise program for obese middle-aged women. This study targeted middle-aged women residing in Gyeonggi-do A, who are obese middle-aged women in their 40s and 50s with a body fat ratio of 30% or more, and had no regular exercise in the past three months. Obese middle-aged women(n=19) were divided into two groups, the Pilates mat exercise program group(n=9) and the control group(n=10), conducting exercise for 60 minutes three times a week for 12 weeks. As a result of analysis, the exercise group had a positive effect on body weight, skeletal muscle mass, body fat mass, body fat percentage, and BMI in body composition, but not in the control group. In the lipid metabolism, the exercise group had a positive effect on TC, TG, HDL-C, LDL-C, and FFA, but not in the control group. These results suggest that the 12-week Pilates mat exercise program conducted in this study is an exercise program that can prevent cardiovascular and chronic diseases in obese middle-aged women.

Age-Dependent Progesterone Metabolism in the Rat Brain (쥐 뇌의 progesterone대사에 미치는 연령의 효과)

  • Han, Beom-Ku;Park, In-Ho;Jo, Do-Hyun
    • Applied Biological Chemistry
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    • v.38 no.1
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    • pp.37-41
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    • 1995
  • The effect of age on the metabolism of progesterone was studied in the rat brain. Metabolic activity was more active in minced tissues than total homogenates. The activity of progesterone $5{\alpha}-reductase(s)$ was increased during postnatal periods(between 5 and 14 days after birth) and thereafter steadily decreased up to the one-fourth level of the fetus. When $5{\alpha}-dihydroprogesterone$ was incubated with brain tissues of various ages, the change in the activity of $3{\alpha}-hydroxysteroid$ oxidoreductase$(3{\alpha}-HSOR)$ was similar to that of $5{\alpha}-reductase(s)$. These results suggest that the reduced formation of total $5{\alpha}-reduced$metabolites was due to the decreased activities of $5{\alpha}-reductase(s)$ and $3{\alpha}-HSOR$. However the level of $3{\beta}-HSOR$ remained constant regardless of the age.

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Effect of Temperature and Body Size on Oxygen Consumption and Ammonia Excretion of Oyster, Crassostrea gigas (굴, Crassostrea gigas의 대사율에 미치는 수온 및 개체크기의 영향)

  • Shin, Yun-Kyung;Hur, Young-Baek;Myeong, Jeong-In;Lee, Sik
    • The Korean Journal of Malacology
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    • v.24 no.3
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    • pp.261-267
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    • 2008
  • The tendency of metabolism in oyster, Crassostrea gigas, was investigated in relation to the water temperature and salinity. Oxygen consumption and ammonia excretion were measured and O:N ratio were calculated according to the water temperature from February 2007 to September 2008 and body size. The relationship between oxygen consumption and body weight has been examined in C. gigas. The weight-specific oxygen consumption rate (mg $O_2$/g/h) varied inversely with size. Oxygen consumption and ammonia excretion increased with an increase in water temperature. O:N ratio measured in this study ranged from 8 to 40 under ordinary sea water and the ratio was 8 at $25^{\circ}C$ and 16 at $10^{\circ}C$. This indicates that oyster mainly use the protein as the primary catabolic substrate during gametogenesis. Lower O:N ratio in winter suggests that oysters have to meet their energy demand by metabolizing protein to survive in stressful conditions such as low temperature and lack of sufficient food supply. This studies will provide the basic data for oyster culture farm in assessing the carrying capacity and sustainable management.

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Studies on Requirement Calorie and Nutrient Intake of College Women Students in Korea (Part 1) (韓國女子大學生의 要求 Calorie 量과 榮養素攝取量에 對한 調査硏究 (第 1 報))

  • Hyun Ki Lee
    • Journal of the Korean Chemical Society
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    • v.8 no.3
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    • pp.93-97
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    • 1964
  • In order to know the Korean college women students expended calorie and nutritional status, a time study and a dietary survey were carried out for ten days, in January 1962, of 28 women students in Pusan Teachers College. (1) Average age of the subjects was 20 years, the height 157.1cm, weight 51. 75kg. and surface area 1.5m$^2$. (2) The structure of their expended energy, in average, was 1303 Cal for basal metabolism, 1563 Cal for quite metabolism, 469Cal for action metabolism and 2032 Cal for spended energy. While their ingested energy was 1880 Cal, which was 152 Cal less than the expenditure. (3) Their in take of protein, iron, vitamin B$_1$ and C were found more than the amount required, while calorie, fat, carbohydrate. calcium, Vitamin A and B$_2$ were less than the amount.

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Inhibitory Effects of Fungal Metabolites Isolated from Foodstuffs on the Growth of Human Cancer Cell Lines (식품유래 곰팡이 대사산물의 항암효과)

  • Im, Hyo-Gwon;Yu, Mi-Hee;Chung, Duck-Wha;Lee, In-Seon
    • Korean Journal of Food Science and Technology
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    • v.38 no.2
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    • pp.262-267
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    • 2006
  • Inhibitory effects of fungal metabolites isolated from foodstuffs on growth of human cancer cell lines were evaluated. Isolated strains were divided into four classes based on color (aerial, reverse), shape, and growth speed. Fungal metabolites extracted with ethyl acetate were investigated for their growth inhibition on six kinds of human cancer cells by MTT assay. Ethyl acetate extract showed high growth inhibition against all cancer cells tested, with D4 exhibiting the strongest growth inhibition effects against Kato III, AGS, Hepa1c1c7, and MDA-MB-231 cancer cells. These results suggest ethyl acetate extract from fungal metabolites as effective natural cancer therapeutic material.

A survey on daily physical activity level, energy expenditure and dietary energy intake by university students in Chungnam Province in Korea (충남지역 대학생의 신체활동수준, 에너지소비량 및 에너지섭취량 조사)

  • Kim, Sun Hyo
    • Journal of Nutrition and Health
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    • v.46 no.4
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    • pp.346-356
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    • 2013
  • This study investigated the daily physical activity level, energy expenditure, energy balance, and body composition and their relationship with university students. The participants were 130 male students ($19.5{\pm}0.5$ yrs) and 139 female students ($19.5{\pm}0.3$ yrs) at a university in Chungnam province. Physical activity level was evaluated by an equation based on 24 hr-activity record and dietary nutrient intake was evaluated using the food record method during a three-day period consisting of two week days and one weekend. Body composition was measured using Inbody 430 (Biospace Co., Cheonan, Korea). As a result, mean body mass index (BMI) of subjects indicated that they had normal weight, however mean body fat ratio was $19.1{\pm}5.4%$ for males and $28.4{\pm}5.0%$ for females, indicating that they had higher than normal weight. Daily mean physical activity level was 1.55 for males and 1.47 for females, which was regarded as 'low active', respectively. Females had more light activity than males (p<0.01). Daily mean energy expenditure was $2,803.5{\pm}788.9$ kcal/d for males and $1,915.4{\pm}510.2$ kcal/d for females (p<0.001). Daily mean dietary energy intake was $2,327.0{\pm}562.5$ kcal/d for males and $1,802.1{\pm}523.6/d$ for females (p<0.001), and daily mean energy balance was $-476.5{\pm}955.9$ kcal/d for males and $-113.3{\pm}728.1$ kcal/d for females (p<0.01). Daily mean dietary intake of protein, vitamins, and minerals, except Ca, satisfied recommended nutrient intake. Daily energy expenditure was positively related to body weight (p<0.01), BMI (p<0.01), and fat free mass ratio (p<0.05), but was negatively related to body fat ratio (p<0.01). In conclusion, subjects had a negative energy balance and low physical activity. They had a normal weight by BMI but had a more fat than normal weight by body fat ratio. This appears to be related to their low physical activity. Thus, nutrition education should be provided for university students in order to increase their physical activity for maintenance of normal weight by body composition and health promotion.

Cell Biological Studies on Brain Formation at the Early Stage of Chick Embryogenesis (초기계배의 뇌 형성에 관한 세포 생물학적 연구)

  • 최임순;주충노;최춘근;김재원;주상옥
    • The Korean Journal of Zoology
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    • v.29 no.3
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    • pp.215-233
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    • 1986
  • The effect of tryptophan on brain formation at the early stage of chick embryo has been investigated morphologically using electron microscope. The electron micrographs of cerebral cortex cells of $5\\sim10$ day old chick embryo, which received 1.0mg of tryptophan showed that the irregularity, evagination and disruption of nuclear membrane and nuclear chromatin condensation, nucleolar chromatin margination and segragation. Hypertrophy of stalks, vesicles, and vacuoles can be seen and dilation and vesiculation of rough endoplamic reticulum and polysome disaggregation occured. Protein and RNA levels and the activity of several enzymes such as lactate dehydrogenase, succinate dehydrogenase, malate dehydrogenase and glucose 6-phosphate dehydrogenase of tryptophan administered group were significantly lower than those of control group suggesting that the tryptophan administration depressed protein biosynthesis resulting in the decrease of enzyme activity. It was found that serotonin content of egg yolk which has been incubated for 10 days were as much as three times that of control egg yolk. It is not clear whether the increase of serotonin content might inhibit intracellular yolk granule degradation which might result in malformation of chick embryo, but it is likely that tryptophan administration might depress protein biosynthesis, consequently, the enzyme biosynthesis would be impaired. This might give rise to improper development of chick embryo.

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The Utilization of Mutton Fat, Tallow, and Lecithin in the Broilers (육계에서의 양지, 우지 및 레시친의 이용)

  • 고태송;오세정;김춘수
    • Korean Journal of Poultry Science
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    • v.6 no.2
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    • pp.83-90
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    • 1979
  • In order to evaluate the effect of lipids on the utilization of the energy and Protein of the diet, the isocaloric and isoprotein diets added with mutton fat, tallow, and lecithin at the levels of two percent and five percent were prepared. The growth of chicken and the feed efficiency were observed on hatched chicken which were fed a commercial diet for the first week, with starters for the next four weeks, and with finisher diets for the last three weeks respectively during the eight weeks of the experiment. Growth rate, feed efficiency, and average body weight gain per day were similar among the chicken fed diets containing various lipids or at the levels of two percent and five percent. The metabolizable energy of the diets was found to be from 2.713kcal to 3.059kcal per gram, and the metabolizability of the gross energy was from 62 percent to 70 percent. Also the metabolizability of basal diet was higher as compared with the diets containing lipids. And the lower energy utilization was found in the broilers fed diets containing five percent lipids than those of two percent, showing not significant difference between them. Daily metabolizable energy of three week old birds ranged from 132kca1 to 168kcal which resulted in also a tendency of lower values in the five percent diets. And daily retained nitrogen of birds ranged from 0.631 gr to 0.738 gr, which showed an increasing tendency on the birds fed five percent mutton fat and tallow in comparison with those of two percent. But the lecithin brought about a reverse tendency. The digestibility of crude fats was found to be from 48 percent to 76 percent, but not significant difference among diets plus lipids or at the levels of two percent and five percent. The birds fed five percent mutton fat and tallow showed a tendency of lower digestibility as. compared with those fed two percent, but the similar results were found between two percent and five percent lecithin fed to the birds. Then, it was tentatively concluded that the effect of the mutton fat on the energy and protein utilization was similar to tallow but resulted different tendency with lecithin.

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